Search results for "SUPPLEMENTATION"

Modulating carbohydrate-based hydrogels as viscoelastic lubricant substitute for articular cartilages

2017

Viscosupplementation is a therapeutic approach for osteoarthritis treatment, where the synovial fluid, the natural lubricant of the joints, is replaced by viscoelastic solutions with rheological properties comparable or better than the starting material. This study presents the development of an innovative platform for viscosupplementation, based on the optimization of polysaccharide-based colloidal hydrogel, aiming to reduce on-site enzyme degradation and enhance the possibility of hyaluronic acid substitution with alternative biomaterials. Catanionic vesicles are proposed as physical crosslinker that can guarantee the formation of a 'soft', tunable network, offering a dual-therapeutic app…

Nutraceuticals and functional foods for the control of plasma cholesterol levels. An intersociety position paper

2018

Current evidence shows that cholesterol management either reduces the likelihood of cardiovascular disease (CVD) or slows down its progression. Hence, it is important that all health professionals make appropriate use of all the available intervention strategies to control risk factors: from dietary improvement and positive lifestyle changes to the use of functional foods, food supplements, and drugs. This review examines the effect of the most frequently occurring cholesterol-lowering substances in functional foods or in supplements across Europe, namely plant sterols and stanols, monacolin K found in red yeast rice, berberine and beta-glucans. We conclude that currently available suppleme…

Protein supplements consumption: a comparative study between the city centre and the suburbs of Palermo, Italy

2014

Background: Protein supplements are extensively used among commercial gym users and athletes. Although demographic information amongst such consumption has been poorly investigated. The aim of this study is to compare protein supplement consumption in commercial gym users, both from the city centre and the suburbs of Palermo, Italy. Methods: A face-to-face questionnaire has been administered to 561 subjects. 207 from the city centre (CC) and 354 from the suburbs (SB) of Palermo, Italy. Protein supplement consumption, frequency of use and association with other dietary supplements has been investigated. Subsequently frequency distribution has been used for demographic assessment. Results: 30…

Effects of protein supplementation in fitness world: A 12-week cross-over studio

2020

The aim of this project was to evaluate the effect of isolated protein supplementation in young amateur athletes. Sixteen subjects aged between 20 and 30 were recruited for this study. Before to start sports performance was assessed at T0, in all subjects, using physical performance test and evaluated body composition. Therefore, the subjects were randomly assigned in two groups (group A and B) of 8 subjects each. The group A start to intake 30 g of protein powder diluted in water after each training session (3 times a week) for six weeks (T0) whilst the group B was the placebo. After 6 weeks (T1), the measurement were repeated for all subjects and the group A became placebo and the group B…

n-3 polyunsaturated fatty acids and HER2-positive breast cancer: interest of the fat-1 transgenic mouse model over conventional dietary supplementati…

2013

Overexpression of the tyrosine kinase receptor ErbB2/HER2/Neu, occurs in 25%-30% of invasive breast cancer (BC) with poor patient prognosis. Even if numerous studies have shown prevention of breast cancer by n-3 fatty acid intake, the experimental conditions under which n-3 fatty acids exert their protective effect have been variable from study to study, preventing unifying conclusions. Due to confounding factors, inconsistencies still remain regarding protective effects of n-3 polyunsaturated fatty acids (PUFA) on BC. When animals are fed with dietary supplementation in n-3 fatty acids (the traditional approach to modify tissue content and decrease the n-6/n-3 ratio) complex dietary intera…

Calcium in the prevention of postmenopausal osteoporosis: EMAS clinical guide

2017

Abstract Introduction Postmenopausal osteoporosis is a highly prevalent disease. Prevention through lifestyle measures includes an adequate calcium intake. Despite the guidance provided by scientific societies and governmental bodies worldwide, many issues remain unresolved. Aims To provide evidence regarding the impact of calcium intake on the prevention of postmenopausal osteoporosis and critically appraise current guidelines. Materials and methods Literature review and consensus of expert opinion. Results and conclusion The recommended daily intake of calcium varies between 700 and 1200 mg of elemental calcium, depending on the endorsing source. Although calcium can be derived either fro…

Perspective: Protein Supplementation in Frail Older Persons: Often Necessary but Not Always Sufficient

2013

COMMENTARY TO THE LETTER TO THE EDITOR

2011

mrh.2011.0274 Auteur(s) : Mario Barbagallo mabar@unipa.it, Ligia J Dominguez Geriatric Unit, Dept. of Internal Medicine and Emergent Pathologies, University of Palermo, Italy Correspondence: M. Barbagallo Dear Editor, We thank Dr Kisters for his comments; we agree with the potentiality of magnesium supplementation in the management of hypertension. However, although our data show the effectiveness of magnesium supplementation to improve endothelial vascular function [1], we would be more [...]

Hyperhomocysteinemia and Cardiovascular Risk: Effect of Vitamin Supplementation in Risk Reduction

2010

Abstract Homocysteine is a sulfur-containing aminoacid produced during metabolism of methionine. Since 1969 the relationship between altered homocysteine metabolism and both coronary and peripheral atherotrombosis has been known; in recent years experimental evidences have shown that elevated plasma levels of homocysteine are associated with an increased risk of atherosclerosis and cardiovascular ischemic events. Several mechanisms by which elevated homocysteine impairs vascular function have been proposed, including impairment of endothelial function, production of Reactive Oxygen Species (ROS) and consequent oxidation of low-density lipids. Folic acid and B vitamins, required for remethyl…

Food provisioning alters infection dynamics in populations of a wild rodent

2015

While pathogens are often assumed to limit the growth of wildlife populations, experimental evidence for their effects is rare. A lack of food resources has been suggested to enhance the negative effects of pathogen infection on host populations, but this theory has received little investigation. We conducted a replicated two-factor enclosure experiment, with introduction of the bacteriumBordetella bronchisepticaand food supplementation, to evaluate the individual and interactive effects of pathogen infection and food availability on vole populations during a boreal winter. We show that prior to bacteria introduction, vole populations were limited by food availability.Bordetella bronchisept…