Search results for "SYSTEMS"

showing 10 items of 11952 documents

Auswirkungen eines neuen Wassersystems auf nosokomiale Kolonisierung oder Infektion mit Pseudomonas aeruginosa

2016

Aim: We aimed to study the impact of new water systems, which were less contaminated with P. aeruginosa, on the incidence of healthcare-associated P. aeruginosa cases (colonizations or infections) in care units that moved to a different building between 2005 and 2014. Methods: Generalized Estimated Equations were used to compare the incidence of P. aeruginosa healthcare-associated cases according to the building. Results: Twenty-nine units moved during the study period and 2,759 cases occurred in these units. No difference was observed when the new building was compared with older buildings overall. Conclusion: Our results did not support our hypothesis of a positive association between wat…

0301 basic medicinelcsh:Public aspects of medicineTrinkwassersystem030106 microbiologylcsh:Rlcsh:QR1-502lcsh:Medicinelcsh:RA1-1270030501 epidemiology610 Medical sciences; Medicineinfection controllcsh:MicrobiologyArticlenosokomiale Infektionen3. Good healthInfektionskontrolle03 medical and health sciences[ SDV.MHEP.MI ] Life Sciences [q-bio]/Human health and pathology/Infectious diseaseswater systemshealthcare-associated infectionsddc: 610[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesNosocomial infectionsPseudomonas aeruginosa0305 other medical scienceGMS Hygiene and Infection Control
researchProduct

Taxonomic Classification for Living Organisms Using Convolutional Neural Networks

2017

Taxonomic classification has a wide-range of applications such as finding out more about evolutionary history. Compared to the estimated number of organisms that nature harbors, humanity does not have a thorough comprehension of to which specific classes they belong. The classification of living organisms can be done in many machine learning techniques. However, in this study, this is performed using convolutional neural networks. Moreover, a DNA encoding technique is incorporated in the algorithm to increase performance and avoid misclassifications. The algorithm proposed outperformed the state of the art algorithms in terms of accuracy and sensitivity, which illustrates a high potential f…

0301 basic medicinelcsh:QH426-470Taxonomic classificationADNCodificació Teoria de laBiologyBioinformaticsMachine learningcomputer.software_genreDNA; genes; taxonomic classification; convolutional neural networks; encodingConvolutional neural networkArticle03 medical and health sciences0302 clinical medicineBiologia -- ClassificacióEncoding (memory)convolutional neural networksGeneticstaxonomic classificationSensitivity (control systems)genesGenetics (clinical)ta113Biology -- Classificationbusiness.industryBiological classificationCoding theoryDNAencodinglcsh:Genetics030104 developmental biologyGenes030220 oncology & carcinogenesisEncodingConvolutional neural networksArtificial intelligenceCoding theorybusinesscomputerGens
researchProduct

An Industrial Automation Course: Common Infrastructure for Physical, Virtual and Remote Laboratories for PLC Programming

2018

<span style="font-family: 'Times New Roman',serif; font-size: 10pt; mso-fareast-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: DE; mso-bidi-language: AR-SA;">This work describes the development of a teaching strategy to leverage current simulation tools and promote learning of industrial automation systems. Specifically, Programmable Logic Controller (PLC) programming in an industrial automation course. We propose an infrastructure where it is possible to work with physical, virtual and mixed laboratories</span>

0301 basic medicinelcsh:T58.5-58.64Computer sciencebusiness.industrylcsh:Tlcsh:Information technologyIndustrial Automation Teaching On-line Education OPC-UA Virtual Laborato-ry Virtual commissioning PLC programmingGeneral EngineeringProgrammable logic controllerAutomationlcsh:TechnologyEnsenyament virtual03 medical and health sciences030104 developmental biologyTheoryofComputation_MATHEMATICALLOGICANDFORMALLANGUAGESLeverage (statistics)businessSoftware engineeringIndustrial automation systemsAutomatitzacióInternational Journal of Online Engineering (iJOE)
researchProduct

Cross-modal interactions as a strategy to enhance salty taste and to maintain liking of low-salt food: a review.

2019

Salt reduction in foods is becoming an important challenge to preserve population health from severe diseases as recommended by different health agencies worldwide. Among the reduction strategies already evaluated in order to lower sodium salt content in foods, the use of cross-modal interactions between taste and odour, regardless of saltiness, was revealed to be a very promising method to improve saltiness perception. Cross-modal odour-taste interaction, as means to enhance salty taste in foods, is reviewed. Salt-related odours can enhance salty taste in water solutions containing a low level of sodium chloride through odour-induced changes in taste perception. Odour-induced saltiness per…

0301 basic medicinelikingTastegenetic structuresmedia_common.quotation_subjectperceptionSodium Chloridesaltiness03 medical and health sciencesFood PreferencesPerceptionLow saltHumansFood scienceAromamedia_common030109 nutrition & dieteticsbiologydairy productsChemistrySalt reductionfood and beveragesTaste PerceptionGeneral Medicinebiology.organism_classificationflavourSodium salt[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry030104 developmental biologyFood systemscross-modal interactionsSalty taste[SDV.AEN]Life Sciences [q-bio]/Food and Nutritionpsychological phenomena and processesFood ScienceFoodfunction
researchProduct

mRNA-Based Vaccines

2021

Increases in the world’s population and population density promote the spread of emerging pathogens. Vaccines are the most cost-effective means of preventing this spread. Traditional methods used to identify and produce new vaccines are not adequate, in most instances, to ensure global protection. New technologies are urgently needed to expedite large scale vaccine development. mRNA-based vaccines promise to meet this need. mRNA-based vaccines exhibit a number of potential advantages relative to conventional vaccines, namely they (1) involve neither infectious elements nor a risk of stable integration into the host cell genome; (2) generate humoral and cell-mediated immunity; (3) are well-t…

0301 basic medicinemRNAinfectious diseaseImmunologyPopulationlcsh:MedicineComputational biologyReviewBiologylipid nanoparticles03 medical and health sciences0302 clinical medicineImmunityDrug DiscoverycancerPharmacology (medical)educationPharmacologyeducation.field_of_studylcsh:Rvaccine constructsdelivery systems030104 developmental biologyInfectious DiseasesInfectious disease (medical specialty)030220 oncology & carcinogenesisHealthy individualsVaccines
researchProduct

Fungal community assemblage of different soil compartments in mangrove ecosystem

2017

AbstractThe fungal communities of different soil compartments in mangrove ecosystem are poorly studied. We sequenced the internal transcribed spacer (ITS) regions to characterize the fungal communities in Avicennia marina root-associated soils (rhizosphere and pneumatophore) and bulk soil compartments. The rhizosphere but not pneumatophore soil compartment had significantly lower fungal species richness than bulk soil. However, bulk soil fungal diversity (Shannon diversity index) was significantly higher than both pneumatophore and rhizosphere soil compartments. The different soil compartments significantly affected the fungal community composition. Pairwise sample analyses showed that bulk…

0301 basic medicinemangrove ecosystemsNitrogenScienceBulk soilfungal communitiescomplex mixturesPlant RootsArticle03 medical and health sciencespneumatophoresSoiljuuristoBotanyDNA Ribosomal SpacerEcosystemEcosystemSoil MicrobiologyRhizospheremaaperäMultidisciplinarybiologyEcologyQmangrovetRFungiSoil chemistryeliöyhteisötSequence Analysis DNAbiology.organism_classificationCarbonekosysteemit (ekologia)030104 developmental biologyAvicennia marinaSoil waterRhizosphereMedicineSpecies richnessAvicenniarhizospheresienetSoil microbiologyMycobiomeScientific Reports
researchProduct

Text mining and expert curation to develop a database on psychiatric diseases and their genes

2017

Psychiatric disorders constitute one of the main causes of disability worldwide. During the past years, considerable research has been conducted on the genetic architecture of such diseases, although little understanding of their etiology has been achieved. The difficulty to access up-to-date, relevant genotype-phenotype information has hampered the application of this wealth of knowledge to translational research and clinical practice in order to improve diagnosis and treatment of psychiatric patients. PsyGeNET (http://www.psygenet.org/) has been developed with the aim of supporting research on the genetic architecture of psychiatric diseases, by providing integrated and structured accessi…

0301 basic medicinemedia_common.quotation_subjectLibrary scienceMental disordersHealth informaticsGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicinePlatformExcellencePolitical scienceDatabases GeneticGeneticsData MiningHumansData miningData Curationmedia_commonGlobal burdenDisordersData curationbusiness.industryMental DisordersData science3. Good health030104 developmental biologyOriginal ArticleChristian ministryGeneral Agricultural and Biological Sciencesbusiness030217 neurology & neurosurgerySoftwareInformation Systems
researchProduct

Motives for buying local, organic food through English box schemes

2018

Purpose The purpose of this paper is to explain the growing interest of English consumers in local organic food sold through box schemes, by providing insights into the motives of customers of such schemes and examining the relationship with their awareness about problems of the agro-food system. Design/methodology/approach A mixed methods approach combined in-depth interviews with 22 box scheme customers with a quantitative survey of 416 consumers, analysed by means of principal component analysis and an ordered logit model. Findings Consumers of small local organic box schemes in England are both altruistically and hedonistically motivated. This includes a strong political motivation to …

0301 basic medicinemedia_common.quotation_subjectMarkets and tradeMixed methods approachSample (statistics)03 medical and health sciencesPolitics0502 economics and businessSettore AGR/01 - Economia Ed Estimo RuraleMainstreamLocal foodQuality (business)Alternative food networkMarketingmedia_commonQuantitative surveyMotivation030109 nutrition & dietetics05 social sciencesAwareneConsumer issuesPolitical consumerismOrganic farmingFood systemsBusiness Management and Accounting (miscellaneous)050211 marketingOrdered logitBusinessFood Science
researchProduct

Superagonistic CD28 stimulation induces IFN‐γ release from mouse T helper 1 cells in vitro and in vivo

2020

Like human Th1 cells, mouse Th1 cells also secrete IFN-γ upon stimulation with a superagonistic anti-CD28 monoclonal antibody (CD28-SA). Crosslinking of the CD28-SA via FcR and CD40-CD40L interactions greatly increased IFN-γ release. Our data stress the utility of the mouse as a model organism for immune responses in humans.

0301 basic medicinemedicine.drug_classImmunologyved/biology.organism_classification_rank.speciesCD40 LigandStimulationchemical and pharmacologic phenomenaBiologyMonoclonal antibodyLymphocyte Activation03 medical and health sciencesInterferon-gammaMice0302 clinical medicineImmune systemCD28 AntigensIn vivomedicineImmunology and AllergyAnimalsHumansSecretionddc:610CD40 AntigensModel organismved/biologyCD28Antibodies Monoclonalhemic and immune systemsTh1 CellsIn vitroCell biology030104 developmental biology030215 immunologySignal Transduction
researchProduct

Hepatic Steatosis Index in Acromegaly: Correlation with Insulin Resistance Regardless of the Disease Control

2018

Objective. In acromegaly, both lipotoxicity secondary to GH excess and insulin resistance have a significant impact on the liver. Ultrasonography has shown poor sensitivity in detecting hepatic steatosis and noninvasive methods have been proposed. We evaluated the hepatic steatosis index (HSI), a validated surrogate index of hepatic steatosis, and we correlated it with disease activity and insulin resistance. Design. Thirty-one patients with newly diagnosed acromegaly were studied at diagnosis and after 12 months of treatment with somatostatin receptor ligands. Methods. Glucose and insulin levels, surrogate estimates of insulin sensitivity, and hepatic steatosis through ultrasonography and …

0301 basic medicinemedicine.medical_specialtyArticle SubjectEndocrinology Diabetes and Metabolismmedicine.medical_treatment030209 endocrinology & metabolismGastroenterologylcsh:Diseases of the endocrine glands. Clinical endocrinologySettore MED/13 - EndocrinologiaCorrelation03 medical and health sciences0302 clinical medicineEndocrinologyInsulin resistanceInternal medicineAcromegalymedicinelcsh:RC648-665Endocrine and Autonomic SystemsSomatostatin receptorbusiness.industryhepatic steatosisInsulinmedicine.diseaseDisease control030104 developmental biologyLipotoxicitySteatosisbusinessResearch ArticleInternational Journal of Endocrinology
researchProduct