Search results for "Saline"

showing 10 items of 261 documents

Pro-Inflammatory Cytokines in Elective Flap Surgery

2006

Surgical trauma releases inflammatory mediators such as pro-inflammatory cytokines. In this prospective, controlled, randomized trial we investigated the release of pro-inflammatory cytokines and monocyte/macrophage activation in patients scheduled for breast reconstruction after mastectomy. Patients were allocated to one of three surgical procedures, differing in complexity and in the need for implants used for reconstruction.Thirty mastectomized women underwent delayed breast reconstruction with the lateral thoracodorsal flap (LTD), the latissimus dorsi flap (LD), or the pedicled transverse rectus abdominis muscle flap (TRAM). Blood samples for TNF, IL-6, IL-8, neopterin, C-reactive prote…

Adultmedicine.medical_specialtyBreast ImplantsMammaplastymedicine.medical_treatmentSiliconesBreast NeoplasmsInflammationNeopterinSurgical FlapsProinflammatory cytokineLeukocyte Countchemistry.chemical_compoundHumansMedicineProspective StudiesSalineMastectomyAgedInterleukin-6Tumor Necrosis Factor-alphabusiness.industryInterleukin-8NeopterinMiddle AgedSurgeryPlastic surgeryC-Reactive ProteinCytokinechemistryCytokinesFemaleSurgerymedicine.symptombusinessBreast reconstructionBiomarkersMastectomyJournal of Surgical Research
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Comparison of the effect of ginger and aloe vera mouthwashes on xerostomia in patients with type 2 diabetes: A clinical trial, triple-blind

2021

Background Ginger and aloe vera are two medicinal herbs mostly used to produce mouthwash. This study aimed to compare the effects of ginger and aloe vera mouthwashes on the xerostomia in patients referred to Bandar Abbas diabetes clinic (Iran). Material and Methods In this triple-blind clinical trial, three groups (n=35 patients in each group) were studied. One group was given aloe vera mouthwash, the other group used ginger mouthwash, and the control group was only given normal saline. All the mouthwashes were used 20 ccs three times daily for 14 consecutive days. The symptoms and severity of xerostomia were measured before and after the intervention by the questionnaire proposed by Fox et…

Adultmedicine.medical_specialtymedicine.medical_treatmentMouthwashesType 2 diabetesGingerIranXerostomiaAloe veralaw.inventionMcNemar's testbone regenerationstomatognathic systemRandomized controlled triallawInternal medicineDiabetes mellitusHumansMedicineIn patientthird molarxenograftAloeGeneral DentistrySalineUNESCO:CIENCIAS MÉDICASAgedtooth extractionOral Medicine and Pathologybiologybusiness.industryResearchMiddle Agedbiology.organism_classificationmedicine.diseaseClinical trialDiabetes Mellitus Type 2OtorhinolaryngologySurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Tolerability and efficacy of high-dose furosemide and small-volume hypertonic saline solution in refractory congestive heart failure

2000

Thirty patients aged 65-85 years, with refractory New York Heart Association (NYHA) class IV congestive heart failure (CHF) were treated with an intravenous infusion of furosemide (250-2000 mg/d) and small-volume hypertonic saline solution (150 mL of 1.4-4.6% NaCl) twice a day for 6 to 12 days. A daily fluid oral intake of 1000 mL and previous cardiac therapy were maintained. Clinical signs and symptoms of CHF, such as dyspnea, edema and weakness, improved, as did severity of illness as defined by NYHA class. The infusion was well tolerated. After a 12-month follow-up, 24 patients (80%) were alive and in the NYHA class assigned on discharge from the hospital. This therapeutic combination is…

Aged 80 and overHeart FailureMaleSaline Solution HypertonicAged; Aged 80 and over; Diuretics; Female; Furosemide; Heart Failure; Humans; Infusions Intravenous; Italy; Male; Saline Solution Hypertonic; Statistics Nonparametric; Survival RateStatistics NonparametricSurvival RateItalyFurosemideDiureticHumansFemaleInfusions IntravenouDiureticsInfusions IntravenousHumanAged
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Ethological analysis of morphine withdrawal with different dependence programs in male mice.

2002

Abstract This work was performed to clarify the differences between a long or short development of morphine dependence as well as between a recently installed or a long-term dependence. Morphine withdrawal in rats is a well-characterized phenomenon but this is not so in mice. A study of the principal withdrawal signs have been performed in mice, evaluating their specificity and particular profile of appearance in each type of dependence. Mice were divided into two groups that received increasing doses of morphine every 24 h, three groups that received increasing doses of morphine twice a day for 3 days, and a control group that received saline. Naloxone-induced opiate withdrawal was evaluat…

AgonistMaleNarcoticsmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentPiloerectionMiceOpioid receptorInternal medicineNaloxoneTremorWeight LossmedicineAnimalsSalineBiological PsychiatryPharmacologyBehavior AnimalMorphinebusiness.industryAntagonistEthologyOpioid-Related DisordersSubstance Withdrawal SyndromeEndocrinologyAnesthesiaToxicityMorphinebusinessmedicine.drugProgress in neuro-psychopharmacologybiological psychiatry
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International variations in associations of allergic markers and diseases in children: ISAAC Phase Two

2009

To cite this article: Weinmayr G, Genuneit J, Nagel G, Bjorksten B, van Hage M, Priftanji A, Cooper P, Rijkjarv M-A, von Mutius E, Tsanakas J, Forastiere F, Doekes G, Garrido JB, Suarez-Varela MM, Braback L, Strachan DP, the ISAAC Phase Two Study Group. International variations in associations of allergic markers and diseases in children: ISAAC Phase Two. Allergy 2010; 65: 766–775. Abstract Background:  Circulating allergen-specific IgE (sIgE) and skin prick tests (SPT) are used to define atopy. Downregulation of local inflammatory responsiveness has been proposed to explain a low prevalence of positive SPTs in less affluent countries. We analysed the association between SPTs, total and all…

Allergyeducation.field_of_studybiologybusiness.industryImmunologyPopulationAeroallergenmedicine.diseaseImmunoglobulin Emedicine.disease_causeHypertonic salineAtopyWheezeImmunologymedicinebiology.proteinImmunology and Allergymedicine.symptombusinesseducationAsthmaAllergy
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Nasal Cellularity in 183 Unselected Schoolchildren Aged 9 to 11 Years

2002

Objective. Although rhinitis is extremely frequent in children, methods for assessing the severity of nasal inflammation produce results with wide variability and hence weak clinical significance. We designed this epidemiologic investigation to define the clinical usefulness of assessing nasal cellularity in children. Methods. We studied 183 of 203 eligible unselected schoolchildren who were aged 9 to 11 years and whose parents gave informed consent and completed a questionnaire on the history of atopic and respiratory symptoms. In all children, nasal swabs were obtained from both nostrils and eluted in saline and slides were prepared from cytospin preparations for staining and white cell c…

Allergymedicine.medical_treatmentRespiratory Tract DiseasesAnti-Inflammatory AgentsMucous membrane of noseLeukocyte CountneutrophilsFlunisolideAnti-Inflammatory Agents; Reproducibility of Results; Fluocinolone Acetonide; Skin Tests; Humans; Rhinitis; Child; Biopsy Needle; Exudates and Transudates; Leukocyte Count; Base Sequence; Respiratory Tract Diseases; Neutrophils; Nitrogen Oxides; Administration Intranasal; Nasal Mucosa; Breath TestsChildRespiratory Tract DiseaseSalineRhinitiSkin Testnasal cellularityBiopsy NeedleNeutrophilschoolchildrenExudates and Transudatesrespiratory systemExudates and TransudateNasal decongestantAnti-Inflammatory AgentFluocinolone AcetonideBreath TestsNasal SwabNitrogen Oxidesmedicine.symptomHumanmedicine.drugmedicine.medical_specialtyReproducibility of ResultNitrogen OxiderhinitisInternal medicineotorhinolaryngologic diseasesmedicineHumansAdministration IntranasalSkin TestsBase Sequencebusiness.industrynasal cellularity; neutrophils; rhinitis; allergy; schoolchildrenReproducibility of Resultsallergymedicine.diseaseNeutrophiliaNasal MucosaPediatrics Perinatology and Child HealthImmunologyNasal administrationbusinessPediatrics
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Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity

2002

AbstractProlonged exposure of 3T3 cells to 0.5 osM hypertonic medium induced the accumulation of hsp70 mRNAs. This increase in mRNA levels required active protein synthesis. A weak and transient activation of heat shock factor 1 (HSF1) was noted, but it was temporally uncoupled to the accumulation of the hsp70 mRNAs. Nuclear run-on assay and transfection experiments showed that hsp70 gene transcription was not affected by hypertonicity. ActD chase experiments showed that during hypertonic treatment, degradation of hsp70 mRNAs was markedly reduced. This effect did not appear to be a general phenomenon since the increase in mRNA level of another gene induced by hypertonicity (ATA2 transporter…

Amino Acid Transport System ATranscription GeneticBiologyTransfectionMiceHeat Shock Transcription FactorsTranscription (biology)Heat shock proteinATA2 mRNAAnimalsHSP70 Heat-Shock ProteinsRNA MessengerHSF1HypertonicityMolecular BiologySaline Solution HypertonicMessenger RNAHeat shock proteinMRNA stabilizationTransfection3T3 CellsCell Biologyhsp70 mRNAMolecular biologyHsp70DNA-Binding ProteinsProtein BiosynthesisRNA stabilizationmRNA stabilizationTranscription FactorsBiochimica et Biophysica Acta (BBA) - Molecular Cell Research
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The excellent biocompatibility and negligible immune response of the titanium heterometallic MOF MUV-10

2021

The Ti-Ca heterometallic MOF MUV-10 exhibits good dispersibility in phosphate buffer and low phosphate-induced degradation in comparison to other MOF systems. It induces no cytotoxicity towards cells of the immune system and no inmune response, making it an attractive candidate for biomedical applications and demonstrating its safe use for other applications.

BiocompatibilityBiomedical Engineeringchemistry.chemical_elementBiocompatible Materials02 engineering and technology010402 general chemistry01 natural sciencesMiceImmune systemMaterials TestingAnimalsHumansGeneral Materials ScienceParticle SizeCytotoxicityMetal-Organic FrameworksTitaniumfungiPhosphate buffered salineImmunityGeneral ChemistryGeneral Medicine021001 nanoscience & nanotechnologyCombinatorial chemistry0104 chemical scienceschemistryDegradation (geology)Calcium0210 nano-technologyTitaniumJournal of Materials Chemistry B
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Prenatal cocaine exposure alters spontaneous and cocaine-induced motor and social behaviors.

2005

The abuse of cocaine in pregnant women could affect emotional behaviors in their descendents. The aim of this work was to evaluate the effects of prenatal cocaine exposure on spontaneous and cocaine-induced motor and social behaviors in mice. Three kinds of prenatal treatment were used: non-treated animals; mice treated daily with physiological saline during the last week of pregnancy; and finally, those treated with cocaine (25 mg/kg) during the same period. Behavioral studies took place on adult males, which were housed in two different conditions: grouped (non-aggressive), or isolated (aggressive). Cocaine-pretreated animals exhibited slight differences in spontaneous motor activity, but…

Biogenic AminesOffspringmedicine.drug_classmedicine.medical_treatmentPhysiologyMotor ActivityToxicologyCellular and Molecular NeuroscienceMiceDevelopmental NeuroscienceCocainePregnancymedicineAnimalsSocial BehaviorSalineBrain ChemistryPregnancyDose-Response Relationship DrugAggressionLocal anestheticPrenatal cocaine exposuremedicine.diseaseHousing AnimalStimulation ChemicalAnesthesiaPrenatal Exposure Delayed EffectsToxicityFemalemedicine.symptomPsychologySocial behaviorNeurotoxicology and teratology
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Compartmentalization of gypsum and halite associated with cyanobacteria in saline soil crusts

2016

The interface between biological and geochemical components in surface crust of a saline soil was investigated using X-Ray Diffraction (XRD), and variable pressure scanning electron microscopy (SEM) in combination with Energy Dispersive X-ray Spectrometry (EDS). Mineral compounds such as halite and gypsum were identified crystallized around filaments of cyanobacteria. A total of 92 genera were identified from the bacterial community based on 16S gene pyrosequencing analysis. The occurrence of the gypsum crystals, their shapes and compartmentalization suggested that they separated NaCl from the immediate microenvironment of the cyanobacteria, and that some cyanobacteria and communities of su…

Biomineralization0301 basic medicineCyanobacteriaGypsumbiomineralisationSettore AGR/13 - Chimica Agraria030106 microbiologychemistry.chemical_elementMineralogySulfur bacteriaSodium ChlorideBiologyengineering.materialCyanobacteriaCalcium SulfateApplied Microbiology and BiotechnologyMicrobiologySoil03 medical and health sciencesX-Ray DiffractionSoil crustRNA Ribosomal 16SSoil MicrobiologyMineralSulfur CompoundsEcologyMedicine (all)biology.organism_classificationSulfurchemistrySettore AGR/14 - PedologiaMicroscopy Electron ScanningengineeringsulfobacteriaSoil crustHaliteSoil microbiologySaline soilBiomineralizationFEMS Microbiology Ecology
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