Search results for "Satu"

Aliciklisko alfa-aminoskābju sintēze

2017

Aliciklisko α-aminoskābju sintēze. Stamberga D., zinātniskie vadītāji Dr.chem. Kauss V. un Dr.h.chem., prof. Zicmanis A. Maģistra darbs, 52 lappuses, 36 attēli, 4 tabulas, 48 literatūras avoti. Latviešu valodā. Maģistra darbā ir apskatītas dažādas bi- un tri-(ali)ciklisko α-aminoskābju sintēžu metodes, kā arī dots ieskats enantioselektīvā Dīlsa-Aldera ciklopievienošanās reakcijā biciklo[2.2.1]heptēna fragmenta sintēzei. Literatūras apskatā apkopota informācija par laika periodu no 1973. līdz 2017. gadam, izmantojot datubāzes SciFinder un Espacenet. Darba gaitā izstrādāta metode (R) un (S)-3-(adamantan-1-il)-2-((treš-butoksikarbonil)amino)propānskābju sintēzei četrās stadijās, (1R,2S,4S)-2-(…

Membrane fatty acid composition and fluidity are involved in the resistance to freezing of Lactobacillus buchneri R1102 and Bifidobacterium longum R0…

2015

International audience; Determinations of membrane fatty acid composition and fluidity were used together with acidification activity and viability measurements to characterize the physiological state after freezing of Lactobacillus buchneri R1102 and Bifidobacterium longum R0175 cells harvested in the exponential and stationary growth phases. For both strains, lower membrane fluidity was achieved in cells harvested in the stationary growth phase. This change was linked to a lower unsaturated-to-saturated fatty acid ratio for both strains and a higher cyclic-to-saturated fatty acid ratio for L. buchneri R1102 alone. These membrane properties were linked to survival and to maintenance of aci…

The droplet evaporation/condensation transition in a finite volume

2003

A fluid in the NVT ensemble at T less than the critical temperature T_c and rho = N/V somewhat in excess of rho_coex (density of the saturated gas in the gas-liquid transition) is considered. For V->infinity, a macroscopic liquid droplet coexists with surrounding saturated gas according to the lever rule. For finite V, droplets can only exist if they exceed a minimum size. A (rounded) first order transition of the system occurs when the droplet evaporates into the supersaturated gas.Simulation evidence for this transition is given for a Lennard-Jones model and interpreted by a phenomenological theory. At the transition, the chemical potential difference mu_t-mu_coex scales like L^(-d/(d+…

Insights on recent advances in lipid metabolism and related disorders.

2004

The effect of spent bleaching earth ageing process on its physicochemical and microbial composition and its potential use as a source of fatty acids …

2014

This study was aimed at investigating the physicochemical and microbiological changes that took place during the ageing process of spent bleaching earth in the presence of autochthonous microorganisms. Research material included fresh spent bleaching earth (SBE0) and the same material after 3 years of storage at the constant temperature of 20 °C, without aeration and moistening (SBE3). Changes in the chemical composition of analysed waste material were observed during its ageing process point to a spontaneous bioconversion of fat substance towards formation and/or release of free saturated fatty acids C16:0 and C18:0 (14.3 g 100 g(-1) D.M.), triterpenes (8.48 g 100 g(-1) D.M.), cholesterol …

Meiofauna ratios as environmental indicators in the profundal depths of large lakes.

1995

Two sets of samples from Lake Paijanne and one from Lake Ladoga were used to examine the relations between the meiofauna and environmental variables. The most obvious indicators of an unpolluted environment were, in order of importance, the true meiofauna/total meiofauna ratio, the proportion of Aeolosomatidae, the proportion of Harpacticoida (excluding C. staphylinus), the meiofauna/macrofauna biomass ratio, the proportion of Naididae and the A. crassa + P. schmeili/true meiofauna ratio. Conversely, the clearest indicators of a polluted environment were the proportion of resting stages of Cyclopinae, the Nematoda/non-resting Copepoda ratio, and the proportions of Tubificidae, Oligochaeta, …

Health benefits of pistachios consumption

2017

The health benefits of nuts, mainly in relation to the improvement of dysmetabolic conditions such as obesity, type 2 diabetes mellitus and the related cardiovascular diseases, have been widely demonstrated. Compared to other nuts, pistachios have a lower fat and caloric content, and contain the highest levels of unsaturated fatty acids, potassium, γ-tocopherol, phytosterols and xanthophyll carotenoids, all substances that are well known for their antioxidant and anti-inflammatory actions. This variety of nutrients contributes to the growing body of evidence that the consumption of pistachios improves health, leading to a greater potential of healthy antioxidant and anti-inflammatory activi…

Adrenic acid Δ4 desaturation and fatty acid composition in liver microsomes of spontaneously diabetic Wistar BB rats

1994

We examined the delta 4 (n-6) desaturation and the fatty acid composition of liver microsomes in the insulin-dependent spontaneously diabetic Wistar Bio-Breeding (BB) rat. The desaturation of adrenic acid to n-6 docosapentaenoic acid was decreased in the normo- and hyperglycemic diabetic rats. Insulin treatment with 1.0 IU. 100 g body weight-1 twice a day for 2 days restored the reduced activity during the hypoglycemic period. The pattern of responses was similar to that of linoleic acid delta 6 and dihomo-gamma-linolenic acid delta 5 desaturases, with a non-parallel relationship between the desaturation system and the glycemia. The microsomal fatty acid composition of BB rat liver reflecte…

Liver oleic acid biogenesis is impaired during the prehypertensive period in the spontaneously hypertensive rat.

2003

In the present study, we have investigated the liver microsomal stearic acid delta9 desaturation, and the fatty acid composition of liver microsomal total lipids in 10- and 30-day-old spontaneously hypertensive rats (SHRs), compared to the normotensive Wistar Kyoto (WKY) control rats. So as to avoid any influence related to the diet, the composition of the milk being different in SHR and WKY strains, the pups were suckled by adoptive normotensive female Wistar. After weaning, the 30-day-old rats were fed a standard commercial diet and then killed. Our results show lower liver microsomal delta9 desaturase activities in the 10- and 30-day-old SHR versus the WKY of the same age. The fatty acid…

High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition.

2011

OBJECTIVE Because of confounding factors, the effects of dietary n-3 polyunsaturated fatty acids (PUFA) on type 1 diabetes remain to be clarified. We therefore evaluated whether fat-1 transgenic mice, a well-controlled experimental model endogenously synthesizing n-3 PUFA, were protected against streptozotocin (STZ)-induced diabetes. We then aimed to elucidate the in vivo response at the pancreatic level. RESEARCH DESIGN AND METHODS β-Cell destruction was produced by multiple low-doses STZ (MLD-STZ). Blood glucose level, plasma insulin level, and plasma lipid analysis were then performed. Pancreatic mRNA expression of cytokines, the monocyte chemoattractant protein, and GLUT2 were evaluate…