Search results for "Science research"

showing 10 items of 45 documents

Development of an Agile Requirements Risk Prioritization Method : A Design Science Research Study

2023

The practice of information systems development (ISD) has changed during the past two decades from very structured approaches to agile ISD methods. However, many methods available for managing requirements-related risks in the literature follow the structured way of doing ISD. If any, few methods offer solutions to prioritize requirements risks for agile ISD projects based on recognizing requirements-related risks and patterns to mitigate these. To fill this gap in the literature, we apply the design science research methodology to develop an agile requirements risk prioritization method together with industry experts (n=54) in Finland and New Zealand in a multi-year study. The method was d…

ketterät menetelmätjärjestelmäsuunnitteludesign science researchagile requirements risk prioritization methodriskienhallintainformation systems developmentvaatimuksettietojärjestelmät
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DESIGN PRINCIPLES OF COLLABORATIVE LEARNING SPACE CONNECTING TEACHERS AND REFUGEE CHILDREN - A DESIGN SCIENCE RESEARCH STUDY

2020

Learning the German language is one of the most critical challenges for refugee children in Germany. It is a prerequisite to allow communication and integration into the educational system. To solve the underlying problem, we conceptualized a set of principles for the design of language learning systems to support collaboration between teachers and refugee children, using a Design Science Research approach. The proposed design principles offer functional and non-functional requirements of systems, including the integration of open educational resources, different media types to develop visual and audio narratives that can be linked to the cultural and social background. This study also illu…

learning technologyoppimisympäristöoppiminenkotoutuminen (maahanmuuttajat)Refugeestorytelling for kidsDesign elements and principleslapset (ikäryhmät)Collaborative learningoppimisalustatSpace (commercial competition)collaborative OERmaahanmuuttajatavoimet oppimateriaalitintergenerational learningsaksan kieliMathematics educationchildren refugeeopetusteknologiaDesign science researchSociologykielen oppiminenpakolaisetoppimateriaaliEDULEARN Proceedings
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The Design Towards a Collaborative Subscription Service : The Case of The Finnish Newspaper Industry

2020

The newspaper industry is challenged with its business models. To stabilize revenues, publishers opted for digital subscriptions for generating additional revenue streams. However, digital subscriptions showcase limited success. News aggregator platforms may promise publishers a pool of paying readers. But platform fees and the loss of customer relationships enact barriers among publishers to join. This study proposes a software prototype based on design science research to address the aforementioned shortcomings by deriving design principles for a collaborative subscription service. Building on the strategic alliance, digital platform and business model literature, this research aims to id…

liiketoimintamallitKnowledge managementComputer sciencekehittämistutkimus02 engineering and technologykustantajatBusiness modelDesign sciencecomputer.software_genreNewspaperNews aggregator020204 information systems0502 economics and business0202 electrical engineering electronic engineering information engineeringRevenueStrategic allianceverkkopalvelutService (business)alustatalousbusiness.industrydesign science05 social sciencescollaborationnewspaper Industrydigital platformverkkoliiketoimintabusiness modelkustannusalaDesign science researchsanomalehdetohjelmistoliiketoimintaprototypebusinesscomputer050203 business & management
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Apoptotic-like Leishmania exploit the host´s autophagy machinery to reduce T-cell-mediated parasite elimination

2015

Apoptosis is a well-defined cellular process in which a cell dies, characterized by cell shrinkage and DNA fragmentation. In parasites like Leishmania, the process of apoptosis-like cell death has been described. Moreover upon infection, the apoptotic-like population is essential for disease development, in part by silencing host phagocytes. Nevertheless, the exact mechanism of how apoptosis in unicellular organisms may support infectivity remains unclear. Therefore we investigated the fate of apoptotic-like Leishmania parasites in human host macrophages. Our data showed--in contrast to viable parasites--that apoptotic-like parasites enter an LC3(+), autophagy-like compartment. The compartm…

log.ph logarithmic phaseT-LymphocytesApoptosisMACS magnetic-associated cell sortingMacrophageMFI mean fluorescence intensityLeishmaniasisMOI multiplicity of infectionanti-inflammatoryLeishmaniaeducation.field_of_studyPhagocytesCFSE carboxyfluorescein succinimidyl esterTGFB transforming growth factorAcquired immune systemapoptotic-like LeishmaniaPS phosphatidylserinehuman primary macrophagesCell biologyβ; TT tetanus toxoidCorrigendumProgrammed cell deathautophagyPopulationAntigen presentationANXA5 annexin VBasic Science Research PapersBiologyPhagocytosisCM complete mediumMAP1LC3/LC3 microtubule-associated protein 1 light chain 3AnimalsHumansMHC major histocompatibility complexIF immunofluorescenceeducationMolecular Biologyimmune evasionPBMCs peripheral blood mononuclear cellsT-cell proliferationIntracellular parasiteMacrophagesstat.ph stationary phaseAutophagyLm LeishmaniaCell BiologyLeishmaniabiology.organism_classificationIL interleukinLAP LC3-associated phagocytosisLAPhMDM human monocyte derived macrophageAutophagy
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Research Perspectives: Reconsidering the Role of Research Method Guidelines for Interpretive, Mixed Methods, and Design Science Research

2021

Information systems (IS) scholars have proposed guidelines for interpretive, mixed methods, and design science research in IS. Because many of these guidelines have also been suggested for evaluating what good or rigorous research is, they may be used as a checklist in the review process. In this paper, we raise the question: To what extent do research guidelines for interpretive, mixed methods, and design science research offer evidence that they can be used to evaluate the quality of research. We argue that scholars can use these guidelines to evaluate what good research is if there is compelling evidence that they lead to certain good research outcomes. We use three well-known sets of gu…

mixed methodsNoticeComputer sciencebusiness.industrydesign sciencemetodologiaInternet privacyresearch guidelinestietojärjestelmätiedeDesign sciencePermissionComputer Science Applicationstheory of scientific methodologyServertutkimusmenetelmätInformation systemtieteenteoriainterpretive researchDesign science researchbusinessCitationPublicationInformation SystemsJournal of the Association for Information Systems
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On enriching requirements engineering work using icons

2014

ohjelmistosuunnitteluiconvaatimusmäärittelykuvakkeetdesign science researchkuvallinen viestintävisualisointiohjelmistotuotantovaatimustenhallintarequirements engineeringkulttuurienvälinen viestintäsidosryhmätviestintä
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Social Science Research in Southeast Asia : the Challenges of Studying Parliamentary Institutions

2019

This paper introduces the challenges of studying parliamentary institutions in Southeast Asia. My focus of research is in three countries’ institutions: national parliaments of Indonesia, Malaysia and Singapore. While in Southeast Asia, it is widely known that studying issues of politics and institutions face challenges – compared to studying culture, for example, this view is arguably no longer valid, however with certainqualification.The comparison of parliamentary tradition between three countries – based on observation of the plenary session - reveals that the effectiveness of parliamentary works is related to parliamentary procedure, and even to the culture of work in the countries. Pa…

procedureparliamentlcsh:H53poliittiset instituutiotParliamentmedia_common.quotation_subjectpolitical cultureFace (sociological concept)Parliamentary procedurelcsh:JQ1-6651Public administrationSocial Science Research Southeast Asia Parliament Procedure Political Culture Indonesia Malaysia SingaporeSoutheast asiaPoliticsPolitical scienceInstitutionmedia_commonlcsh:Social sciences and state - Asia (Asian studies only)SingaporeparlamentitMalaysiapoliittinen kulttuuriMalesiaSoutheast Asiapolitiikantutkimuslcsh:History of Asialcsh:Political institutions and public administration - Asia (Asian studies only)lcsh:DS1-937Work (electrical)Indonesiasocial science researchPolitical cultureKaakkois-Aasia
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The Design Science Research Process : A Model for Producing and Presenting Information Systems Research

2006

The authors design and demonstrate a process for carrying out design science (DS) research in information systems and demonstrate use of the process to conduct research in two case studies. Several IS researchers have pioneered the acceptance of DS research in IS, but in the last 15 years little DS research has been done within the discipline. The lack of a generally accepted process for DS research in IS may have contributed to this problem. We sought to design a design science research process (DSRP) model that would meet three objectives: it would be consistent with prior literature, it would provide a nominal process model for doing DS research, and it would provide a mental model for p…

process modelcase studydesign sciencedesign science research processrequirements elicitationrequirements engineeringinformation systems development
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Artificial intelligence centric scientific research on COVID-19 : an analysis based on scientometrics data

2023

AbstractWith the spread of the deadly coronavirus disease throughout the geographies of the globe, expertise from every field has been sought to fight the impact of the virus. The use of Artificial Intelligence (AI), especially, has been the center of attention due to its capability to produce trustworthy results in a reasonable time. As a result, AI centric based research on coronavirus (or COVID-19) has been receiving growing attention from different domains ranging from medicine, virology, and psychiatry etc. We present this comprehensive study that closely monitors the impact of the pandemic on global research activities related exclusively to AI. In this article, we produce highly info…

research analysiscomputer science researchComputer Networks and CommunicationsCOVID-19skientometriikkatekoälyartificial intelligencekoronaviruksetbibliometric analysisHardware and ArchitectureMedia TechnologypublicationsSoftwaretieteellinen julkaisutoimintacoronavirus researchbibliometriikka
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Advancing Design Science Research with Solution-based Probing

2019

We propose solution-based probing as an extension of action design research. The core idea is that researchers bring a prototype solution (probe) into one or more fields and explore to synthesize robust and generalizable design knowledge, along with knowledge of the phenomena and correlations we discover. We believe proposing solutions creates opportunities for researchers to innovate and to document the impact. In addition, solutions can be effective probes for advancing theory, in terms of design theories and in creating exploratory foundations for behavioral and causal theory. We illustrate solution-based probing with four exemplar studies in the areas governance of municipalities, polic…

solution-based probingsuunnitteludesign science research10009 Department of InformaticsteknologiaSystems engineeringorganisaatiotSociologyDesign science researchorganizational systemsratkaisut000 Computer science knowledge & systemsProceedings of the Annual Hawaii International Conference on System Sciences
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