Search results for "Screen"
showing 10 items of 1374 documents
Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining
2012
Purpose: The aim of this study was to demonstrate that modern data mining tools can be used as one step in reducing the labor necessary to produce and maintain systematic reviews. Methods: We used four continuously updated, manually curated resources that summarize MEDLINE-indexed articles in entire fields using systematic review methods (PDGene, AlzGene, and SzGene for genetic determinants of Parkinson disease, Alzheimer disease, and schizophrenia, respectively; and the Tufts Cost-Effectiveness Analysis (CEA) Registry for cost-effectiveness analyses). In each data set, we trained a classification model on citations screened up until 2009. We then evaluated the ability of the model to class…
Decagram-Scale Synthesis of Multicolor Carbon Nanodots: Self-Tracking Nanoheaters with Inherent and Selective Anticancer Properties
2022
Carbon nanodots (CDs) are a new class of carbon-based nanoparticles endowed with photoluminescence, high specific surface area, and good photothermal conversion, which have spearheaded many breakthroughs in medicine, especially in drug delivery and cancer theranostics. However, the tight control of their structural, optical, and biological properties and the synthesis scale-up have been very difficult so far. Here, we report for the first time an efficient protocol for the one-step synthesis of decagram-scale quantities of N,S-doped CDs with a narrow size distribution, along with a single nanostructure multicolor emission, high near-infrared (NIR) photothermal conversion efficiency, and sel…
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives
2014
A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…
Test R-W jako trafne narzędzie w badaniach przesiewowych z zakresu psychologii pracy
2018
The R-W test is a tool examining the speed and accuracy of thinking used in labor psychology. It is described as a tool „filled with the intellectual component”, however, there is no validation data in the literature confirming that the R-W test exam some aspect of intellectual abilities. To fill this gap, validation studies were conducted. In the fi rst one, conducted on a group of drivers (N=105), the R-W test relationship with the complex reaction time, attention, as well as the participants level of education were revealed. In study 2 conducted on a group of students (N=150) the relationship between the R-W test and fl uid intelligence, perceptivity and attention, as well as anxiety as …
Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy
2015
ABSTRACT A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla KPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla KPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla KPC-3 ::Tn 4401a caused by intramolecular transposition events were detected in the plasmid.
Techno-economic pre-feasibility study of wind and solar electricity generating systems for households in Central Finland
2014
The objective of this work is to investigate the viability of a wind, PV or hybrid wind-PV system supplemented with battery storage for electricity production to meet the electricity consumption of a typical household apartment in Central Finland. The assessment criteria for the analysis were cost of energy and total net present cost of each system configuration. We selected the Hybrid Optimization Model for Electric Renewables (HOMER) software, RETScreen, and PVsyst in our analysis and finally only HOMER was considered for performing system optimization analysis because of the creditability of its results. A PV-battery system is recognized as the most economically feasible option in our si…
Associations of near work time, watching TV, outdoors time, and parents' myopia with myopia among school children based on 38-year-old historical dat…
2021
Purpose To study the prevalence and risk factors of myopia with data from a questionnaire study conducted in 1983 among Finnish school children. Methods School children (n = 4 961) from the 1st, 5th and 8th grades of school (7-, 11- and 15-year-olds) in Central Finland were screened for vision followed by a questionnaire, which was returned by 4 352 (87.7%) participants. Myopia was categorized based on the questionnaire. Items concerned daily time spent on near work and outdoor activities, excluding time spent at school, watching TV and parental myopia and the associations of myopia with these factors were studied. Results The prevalence of myopia was 3%, 15% and 27% among the 7-, 11- and 1…
Urban Screens in Turin and Milan: Design, Public Art and Urban Regeneration
2009
Urban screen e media architecture e l'esperienza mediale nello spazio urbano. Il saggio analizza nello specifico gli esempi dell'urban screen in piazza Duomo a Milano e le esperienze di light design urbano e screen informativi a Torino.
Revisiting a Previously Validated Temperament Test in Shelter Dogs, Including an Examination of the Use of Fake Model Dogs to Assess Conspecific Soci…
2019
This study assessed the feasibility and reproducibility of a previously validated temperament test (TT) for shelter dogs. The test was developed to measure dog behaviour in the kennel, and traits of sociability towards people and other dogs, docility to leash, playfulness, cognitive skills, and reactivity. We introduced the use of differently sized fake dogs to check their appropriateness in correctly assessing sociability to dogs to broaden its applicability (as the original study used real stimulus dogs). We hypothesised that dogs&rsquo
“If you can’t stand the meat, stay out of the kitchen” : Translation of verbal humour in television series Coupling
2009
Suurin osa Suomessa näytettävistä televisio-ohjelmista on vieraskielisiä. Monet näistä ohjelmista ovat komedioita, joissa huumori usein perustuu sanaleikkeihin ja verbaaliseen huumoriin. Tästä syystä on tärkeää kiinnittää huomiota näiden televisio-ohjelmien suomenkielisiin käännöksiin. Tämän tutkimuksen tarkoituksena on selvittää, millä tavoin kääntäjät selviytyvät hankalista ja usein mahdottomista sanaleikeistä sekä kulttuuriin liittyvästä huumorista. Tarkoituksena on myös ottaa selvää, mitä eri strategioita kääntäjä käyttää hankalaa vitsiä kääntäessään. Tämän tutkimuksen aineistona käytettiin brittiläistä komediaohjelmaa Paritellen, koska samankaltaisia tutkimuksia on aiemmin tehty amer…