Search results for "Screen"

showing 10 items of 1374 documents

Routine HCV PCR screening of blood donations to identify early HCV infection in blood donors lacking antibodies to HCV

2001

BACKGROUND: Detection of early hepatitis C infection of blood donors is still a major problem for blood transfusion. Common anti-HCV screening assays show differences in sensitivity and specificity. The often mild symptoms of acute hepatitis C also cause difficulties in the identification of early HCV infection. The feasibility and efficacy of routine screening of blood donations for HCV RNA were investigated. STUDY DESIGN AND METHODS: Blood donations (n = 251,737) were screened for HCV RNA over 4 years. RNA extraction, amplification, and detection were done by two commercial HCV PCR kits (HCV Cobas Amplicor and HCV Cobas Amplicor 2.0, Roche Diagnostics). Screening was done by pool testing …

Blood transfusionmedicine.medical_treatmentHepacivirusImmunologyBlood DonorsHepacivirusPolymerase Chain ReactionSensitivity and SpecificitySerologymedicineHumansMass ScreeningImmunology and AllergyAspartate AminotransferasesMass screeningbiologybusiness.industryvirus diseasesAlanine TransaminaseHematologyHepatitis CHepatitis C Antibodiesbiology.organism_classificationmedicine.diseaseHepatitis CVirologydigestive system diseasesImmunologybiology.proteinFeasibility StudiesRNA ViralRNA extractionViral diseaseAntibodybusinessFollow-Up StudiesTransfusion
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The preventive care of medication-related osteonecrosis of the jaw (MRONJ): a position paper by Italian experts for dental hygienists

2022

Abstract Purpose The prevention and early diagnosis of medication-related osteonecrosis of the jaw (MRONJ) is fundamental to reducing the incidence and progression of MRONJ. Many in the field believe that dental hygienists should play an integral role in primary and secondary MRONJ prevention. However, to date, very few publications in the literature have proposed standardised MRONJ protocols, which are dedicated to dental hygienists. The aim of this study was to provide guidance to the health care providers managing MRONJ. Methods The expert opinion in this study was developed by dental hygienists from the main Italian technical-scientific associations (Italian Dental Hygienists Associatio…

Bone Density Conservation AgentsDiphosphonatesOsteonecrosis of the jawRisk factorsOncologyDental hygienistsIncidencePreventionHumansDental hygienists; MRONJ; Osteonecrosis of the jaw; Periodontal screening score; Prevention; Risk factorsBisphosphonate-Associated Osteonecrosis of the JawPeriodontal screening scoreMRONJSupportive Care in Cancer
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Near-infrared emitting fluorescent homobimetallic gold(I) complexes displaying promising in vitro and in vivo therapeutic properties

2021

International audience; Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method based on the combination of two agents that have no effect when applied individually: 10B and thermal neutrons. Exclusively, the combination of both produces an effect, whose extent depends on the amount of 10B in the tumor but also on the organs at risk. It is not yet possible to determine the 10B concentration in a specific tissue using non-invasive methods. At present, it is only possible to measure the 10B concentration in blood and to estimate the boron concentration in tissues based o…

Boron Compoundsinorganic chemicalsCell SurvivalInfrared RaysAntineoplastic Agents01 natural sciencesMiceStructure-Activity Relationship03 medical and health sciencesOptical imagingCoordination ComplexesIn vivoDrug DiscoveryTumor Cells CulturedAza-bodipyAnimalsHumans[CHIM]Chemical SciencesNir fluorescenceComputingMilieux_MISCELLANEOUSCell ProliferationFluorescent Dyes030304 developmental biologyPharmacologyAza CompoundsMice Inbred BALB C0303 health sciencesDose-Response Relationship DrugMolecular Structure010405 organic chemistryChemistryOptical ImagingOrganic ChemistryNear-infrared spectroscopyNeoplasms ExperimentalGeneral MedicineFluorescenceIn vitro3. Good health0104 chemical sciencesBiophysicsGoldDrug Screening Assays AntitumorCancer cell lines
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P1475Impact of automatic screening and parasternal rights positions in the eligibility of patients with hypertrophic cardiomyopathy for subcutaneous …

2020

Abstract Background A high percentage of failures in the detection of QRS and T wave in patients (pts) with hypertrophic cardiomyopathy (HCM) have been reported. This finding would prevent them from being eligible for an implantable subcutaneous automatic defibrillator (S-ICD). However, recently 2 changes in the detection have been proposed, automatic screening and the use of right parasternal position of the lead.  The aim of our work was to study if the elegibility proportion of patients  was increased with both 2 advacements. Methods We included 31 patients (18 male)with a diagnosis of HCM and at least 1 risk factor for sudden death, in follow-up at the outdoor clinic of of 2 cardiology …

Brachial Plexus Neuritismedicine.medical_specialtySupine positionScreening testbusiness.industryHypertrophic cardiomyopathymedicine.diseaseSudden deathParasternal linePhysiology (medical)Internal medicinemedicineCardiologyImplantCardiology and Cardiovascular MedicinebusinessEP Europace
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Age, Health Beliefs and Breast Cancer Screening Program Participation in Valencian Community, Spain

2004

BACKGROUND: Age has a significant bearing on health beliefs related to participating in breast cancer screening programs. This study is aimed at analyzing the breast cancer-related beliefs and attitudes influencing screening program participation among different age groups. METHODS: In a transversal study, a comparison is drawn between the health-related beliefs of a group of women participating in a screening program and a group of non-participating women, taking into account three age ranges (under age 50 (N = 279), 50-60 age range (N = 463), and over age 60 (N = 271). RESULTS: Some variables significantly differ between the participating and non-participating women solely in certain subg…

Breast cancer screeningBreast cancerAge groupsmedicine.diagnostic_testCross-sectional studybusiness.industryAttendanceMedicineGeneral MedicineMammography screeningbusinessmedicine.diseaseDemographyRevista Española de Salud Pública
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Mammogram segmentation by contour searching and massive lesion classification with neural network

2004

The mammography is the most effective procedure for an early diagnosis of the breast cancer. In this paper, an algorithm for detecting massive lesions in mammographic images will be presented. The database consists of 3762 digital images acquired in several hospitals belonging to the MAGIC-5 collaboration. A reduction of the surface under investigation is achieved, without loss of meaningful information, through segmentation of the whole image, by means of a ROI Hunter algorithm. In the following classification step, feature extraction plays a fundamental role: some features give geometrical information, other ones provide shape parameters. Once the features are computed for each ROI, they …

Breast cancerMassive lesion classificationContour searchingMammography X ray screens MIAS databaseRegion-of-interest (ROI)
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Can 3D Digital Breast Tomosynthesis (DBT) improve breast malignant pathology detection? A case-to-case imaging comparison between 3D DBT and 2D Mammo…

2014

Learning objectives Background Findings and procedure details Conclusion Personal information References

Breast Mammography Digital radiography Screening Computer Applications-3D eLearning Cancer Education and traininggenetic structuresComputer Applications-3DeducationEducation and trainingDigital radiographyScreeningeLearningBreastMammographyCancer
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Cancer screening and health system resilience: Keys to protecting and bolstering preventive services during a financial crisis

2012

The aim of this paper is to elucidate the rationale for sustaining and expanding cost-effective, population-based screening services for breast, cervical and colorectal cancers in the context of the current financial crisis. Our objective is not only to promote optimal delivery of high-quality secondary cancer prevention services, but also to underline the importance of strengthening comprehensive cancer control, and with it, health system response to the complex care challenges posed by all chronic diseases. We focus primarily on issues surrounding planning, organisation, implementation and resources, arguing that given the growing cancer burden, policymakers have ample justification for e…

BudgetsCancer ResearchEconomic growthNational Health ProgramsCost-Benefit Analysismedia_common.quotation_subjectPopulationPublic policyContext (language use)Population healthFinancial managementPredictive Value of TestsNeoplasmsPreventive Health ServicesCancer screeningHumansMass ScreeningOrganizational ObjectivesMedicinePolicy Makingeducationmedia_commoneducation.field_of_studyGovernmentEvidence-Based Medicinebusiness.industryHealth PolicyEnvironmental resource managementHealth Care CostsHealth PlanningEconomic RecessionOncologyPractice Guidelines as TopicPsychological resiliencebusinessDelivery of Health CareEuropean Journal of Cancer
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Remembered, Read and Experienced Time in Virtual Text (= Tempo lembrado, lido e experienciado no texto virtual)

2015

In this article I will scrutinize Screen (2002, by WARDRIP-FRUIN & al.), a literary work set and experienced in a CAVE Virtual Reality environment, especially from the perspective of its temporal aspects. There are obvious themes of remembering, forgetting and textually constructing the past in this work, but most notably, Screen emphasizes the temporality of the reading act itself. I will analyze this highly special work in relation to the remembered, read, and bodily experienced time, and thus, attempt to better understand both the notion of fictive time and the temporality of fiction. peerReviewed

CAVEfictional timescreenvirtual textvirtuaalitodellisuus
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Catumaxomab: a bispecific trifunctional antibody.

2009

The trifunctional bispecific monoclonal antibody catumaxomab has two binding specificities directed at epithelial cell adhesion molecule (EpCAM) and the T-cell antigen CD3. With its Fc-fragment, catumaxomab additionally binds accessory cells such as dendritic cells, macrophages and natural killer cells. The trifunctional approach thus leads to unrestricted but specific killing of epithelial tumor cells by major histocompatibility complex without the need for preactivation or external costimulation. The tumor-associated antigen EpCAM is strongly expressed in carcinomas of various origins including colon, rectum, ovarian, gastric, esophagus, lung, pancreas, breast and head and neck. Expressio…

CD3CatumaxomabAntineoplastic AgentsMajor histocompatibility complexchemistry.chemical_compoundAntigenAntigens NeoplasmNeoplasmsAntibodies BispecificMedicineAnimalsHumansPharmacology (medical)PharmacologybiologyBispecific monoclonal antibodybusiness.industryDrug Administration RoutesModels ImmunologicalEpithelial cell adhesion moleculeGeneral MedicineTrifunctional antibodychemistrybiology.proteinCancer researchAntibodyDrug Screening Assays Antitumorbusinessmedicine.drugDrugs of today (Barcelona, Spain : 1998)
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