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showing 10 items of 7305 documents

Osteonecrosis of the jaws in patients assuming oral bisphosphonates for osteoporosis: A retrospective multi-hospital-based study of 87 Italian cases

2013

Abstract Background Bisphosphonates (BPs) are currently the chief drugs for the prevention/treatment of osteoporosis; one of their adverse effects is the osteonecrosis of the jaw (BRONJ). The primary endpoints of this multi-center cross-sectional study are: i) an observation of the clinical features of BRONJ in 87 osteoporotic, non-cancer patients; and ii) an evaluation of their demographic variables and comorbidities. Methods 87 BRONJ patients in therapy for osteoporosis with BPs from 8 participating clinical Italian centers were consecutively identified and studied. After BRONJ diagnosis and staging, comorbidities and data relating to local and drug-related risk factors for BRONJ were col…

medicine.medical_specialtyTime FactorsMultivariate analysisHeart DiseasesOsteoporosisSettore MED/50 - Scienze Tecniche Mediche ApplicateAdministration OralMandibleOsteonecrosis jawHospital based studyAdrenal Cortex HormonesRisk FactorsSettore MED/28 - Malattie OdontostomatologicheInternal medicineDiabetes MellitusInternal MedicinemedicineHumansIn patientRisk factorOral bisphopshonateAdverse effectOsteoporosis PostmenopausalAgedRetrospective StudiesAged 80 and overAlendronateBone Density Conservation AgentsDiphosphonatesbusiness.industryLiver DiseasesIncidence (epidemiology)Age FactorsMiddle Agedmedicine.diseaseSurgeryCross-Sectional StudiesItalyOral bisphopshonates; Osteonecrosis jaws; OsteoporosisHypertensionMultivariate AnalysisOsteoporosisBisphosphonate-Associated Osteonecrosis of the JawFemaleOsteonecrosis of the jawbusiness
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Successful transcatheter aortic valve-in-valve implantation in a patient having a chronic type A aortic dissection

2017

medicine.medical_specialtyTranscatheter aortic030204 cardiovascular system & hematologyTranscatheter Aortic Valve Replacement03 medical and health sciencesImaging Three-Dimensional0302 clinical medicineInternal medicineHumansMedicineAgedAortic dissectionAortic Aneurysm Thoracicbusiness.industryAngiographyAortic Valve Stenosis030229 sport sciencesmedicine.diseaseEchocardiography DopplerValve in valveAortic ValveHeart Valve ProsthesisChronic DiseaseCardiologyFemaleTomography X-Ray ComputedCardiology and Cardiovascular MedicinebusinessEuropean Heart Journal
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Normal Doppler Reference Values of the Pericallosal Artery

2015

Purpose: To provide the normal reference values of the Doppler flow of the pericallosal artery in relation to gestational age from 18 to 41 weeks of gestation. Materials and Methods: The pericallosal artery (PCA) was studied in 466 normal pregnancies. The pulsed Doppler evaluation of the pericallosal artery was done in A3 and A4 segments, and records from PI, RI and Vmax were studied. Results: The resistance index of the pericallosal artery in A3 / A4 segments exhibits a plateau from 18 to 31 weeks of gestation. After 31 weeks, a marked decrease becomes apparent. The pulsatility index of the pericallosal artery in A3 / A4 segments shows a plateau until 36 weeks of gestation. During the fina…

medicine.medical_specialtyUltrasonography Doppler TranscranialHemodynamicsGestational AgeUltrasonography PrenatalCorpus Callosumsymbols.namesakeText miningPregnancyReference ValuesInternal medicineHumansMedicineRadiology Nuclear Medicine and imagingFetusPregnancybusiness.industryInfant NewbornGestational ageAnatomyCerebral ArteriesPericallosal Arterymedicine.diseaseCross-Sectional Studiesmedicine.anatomical_structurePulsatile FlowReference valuesCardiologyVascular resistancesymbolsGestationFemaleVascular ResistancebusinessNuclear medicineDoppler effectUltraschall in der Medizin - European Journal of Ultrasound
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Intravesical Treatment of Superficial Urinary Bladder Tumours with Adriamycin

1980

Personal experience resulted in the observation that intravesical Adriamycin (ADM) is effective in some patients with multiple or diffuse papillary bladder tumours. A review of the literature shows that similar results have been obtained elsewhere, especially in Japan and Sweden. The response rate was higher if single doses of at least 50 mg were employed. Intravesical instillations of ADM appear to be valuable also in the treatment of carcinoma in situ and in prophylactic treatment after transurethral resection (TUR) of papillary bladder tumours.

medicine.medical_specialtyUrinary bladderbusiness.industryCarcinoma in situUrologymedicine.diseaseResectionNeck of urinary bladderTransitional cell carcinomaIntravesical treatmentmedicine.anatomical_structureIntravesical instillationmedicinebusinessProphylactic treatment
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Adriamycin Permeability of the Rat Bladder under Different Conditions

1983

Abstract Fifty female Sprague-Dawley rats were treated with 1.4 or 2.4 mg. adriamycin intravesically. Radioimmunological measurement of serum concentrations were performed up to 3 hours post-instillation in normal bladder mucosa, cystitis, and after electrocoagulation, under different filling conditions, as well as with the use of a detergent (Tween 80). The serum concentrations achieved were markedly higher after electrocoagulation or cystitis; altogether they reached only 1/6,000 of the instilled concentration. These studies on the rat bladder suggest that perioperative instillation of adriamycin to prevent recurrence is not contraindicated shortly before or after transurethral resection …

medicine.medical_specialtyUrologymedicine.medical_treatmentUrinary BladderUrologyPolysorbatesPermeabilityElectrocoagulationAbsorptionResectionCystitisElectrocoagulationmedicineAnimalsRat Bladderbusiness.industryRats Inbred StrainsPerioperativeSerum concentrationRatsSurgeryDoxorubicinPermeability (electromagnetism)Normal bladderFemalebusinessJournal of Urology
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Direct Oral Anticoagulants versus Vitamin K Antagonists in Patients Aged 80 Years and Older.

2021

The effectiveness of direct oral anticoagulants (DOAC) is non-inferior to vitamin K antagonists (VKA) to treat atrial fibrillation and venous thromboembolism (VTE). In this cross-sectional study, we compared older persons taking DOACs to those taking VKAs. We included ambulatory individuals ≥80 years, affiliated to Mutualité Sociale Agricole of Burgundy, who were refunded for a medical prescription in September 2017. The demographic conditions, registered chronic diseases (RCD), and number and types of prescribed drugs were compared in the DOAC group and VKA group. Of the 3190 included individuals, 1279 (40%) were prescribed DOACs and 1911 (60%) VKAs. Individuals taking VKAs were older than…

medicine.medical_specialtyVitamin KDigoxinmedicine.drug_classHealth Toxicology and MutagenesisAdministration Oral030204 cardiovascular system & hematologyVitamin kdirect oral anticoagulantsArticle03 medical and health sciences0302 clinical medicineInternal medicineAtrial FibrillationMedicineHumans030212 general & internal medicineMedical prescriptionAgedAged 80 and overbusiness.industryAnticoagulantanticoagulantPublic Health Environmental and Occupational HealthRFurosemideAnticoagulantsAtrial fibrillationVenous Thromboembolismmedicine.diseaseaged 80 and overvitamin K antagonistsCross-Sectional StudiesHeart failureAmbulatoryMedicineFemalebusinessmedicine.drugInternational journal of environmental research and public health
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Normative values for musculoskeletal- and neuromotor fitness in apparently healthy Norwegian adults and the association with obesity: a cross-section…

2016

Background Up-to-date research on musculoskeletal- and neuromotor fitness (MSMF) is lacking. The aims of the present paper were to a) establish normative values of MSMF by gender and age, and b) to assess how much of the variance in MSMF can be explained by obesity in adults. Methods A random selection of 726 Norwegians (20–65 years) participated in a national cross-sectional study. Muscular endurance, muscular strength, explosive power, flexibility and balance were assessed in addition to waist circumference (WC). Results Females displayed significantly higher scores compared to males on muscular endurance of the back extensors and on the flexibility tests (p < 0.001). Males displayed sign…

medicine.medical_specialtyWaistSports medicineCross-sectional studyPhysical fitnessPhysical Therapy Sports Therapy and Rehabilitation030204 cardiovascular system & hematologyPhysical strengthmuscular power03 medical and health sciences0302 clinical medicinemedicineOrthopedics and Sports MedicineBalance (ability)business.industryRehabilitationpublic health030229 sport sciencesreference valuesmedicine.diseaseObesitymobilityfatnessPeer reviewmuscular fitnessPhysical therapyphysical fitnessneuromuscular fitnessbusinessResearch Article
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Effect of Olympic Weight Category on Performance in the Roundhouse Kick to the Head in Taekwondo

2012

Effect of Olympic Weight Category on Performance in the Roundhouse Kick to the Head in Taekwondo In taekwondo, kick performance is generally measured using impact force and time. This study aimed to analyse performance in the roundhouse kick to the head according to execution distance between and within Olympic weight categories. The participants were 36 male athletes divided into three categories: featherweight (n = 10), welterweight (n = 15) and heavyweight (n = 11). Our results show that taekwondo athletes in all weight categories generate a similar relative impact force. However, the results indicate that weight has a large impact on kick performance, particularly in relation to total r…

medicine.medical_specialtyWeight CategoriesbiologyAthletesHead (linguistics)execution distanceTotal responsetaekwondo combatPhysical Therapy Sports Therapy and Rehabilitationbiology.organism_classificationbiomechanicsbody massPhysical medicine and rehabilitationSection I – KinesiologyPhysiology (medical)medicineSimulationResearch ArticleJournal of Human Kinetics
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Associations of physical activity, fitness, and body composition with heart rate variability–based indicators of stress and recovery on workdays: a c…

2014

Background. The purpose of this study was to investigate how physical activity (PA), cardiorespiratory fitness (CRF), and body composition are associated with heart rate variability (HRV)-based indicators of stress and recovery on workdays. Additionally, we evaluated the association of objectively measured stress with self-reported burnout symptoms. Methods. Participants of this cross-sectional study were 81 healthy males (age range 26–40 y). Stress and recovery on workdays were measured objectively based on HRV recordings. CRF and anthropometry were assessed in laboratory conditions. The level of PA was based on a detailed PA interview (MET index [MET-h/d]) and self-reported activity class…

medicine.medical_specialtyWorking hoursCross-sectional studyPSYCHOSOCIAL STRESSHRVPhysical activityphysical activityRATE DYNAMICSEXERCISEBurnoutToxicologyBody compositionBody fat percentagerecoveryBMIRecoveryInternal medicinemedicineHeart rate variabilityBody fat percentageCardiorespiratory fitnesskehonkoostumusWork stress2. Zero hungercardiorespiratory fitnessPhysical activitybusiness.industryResearchPublic Health Environmental and Occupational HealthFAT DISTRIBUTIONMENCardiorespiratory fitnesswork stressAnthropometrybody fat percentage3142 Public health care science environmental and occupational healthtyöaikaRISK-FACTORSBURNOUTPhysical therapyWEIGHTbusinessOBESE WOMENSafety ResearchBody mass indexAUTONOMIC ACTIVITYJournal of Occupational Medicine and Toxicology
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Definition of the Rectum An International, Expert-based Delphi Consensus

2019

Mini: A radiological, anatomic distinction between the rectum and sigmoid colon was agreed by consensus of international experts in rectal cancer using the Delphi Technique. Use of this landmark, “the sigmoid take-off,” may harmonize efforts in research and clinical practice to improve patient outcomes. Background: The wide global variation in the definition of the rectum has led to significant inconsistencies in trial recruitment, clinical management, and outcomes. Surgical technique and use of preoperative treatment for a cancer of the rectum and sigmoid colon are radically different and dependent on the local definitions employed by the clinical team. A consensus definition of the rectum…

medicine.medical_specialtyanatomyRESECTIONConsensusDelphi TechniqueColorectal cancerAttitude of Health PersonnelDelphi methodRectumMesorectumGUIDELINESdigestive system03 medical and health sciencesAll institutes and research themes of the Radboud University Medical Center0302 clinical medicineColon SigmoidCOLONTumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14]MANAGEMENTmedicineHumansPREOPERATIVE RADIOTHERAPYmedicine.diagnostic_testbusiness.industryRectal NeoplasmsGeneral surgeryRectumSigmoid colonMagnetic resonance imagingSigmoid functionmedicine.diseaseCANCERdigestive system diseasessigmoidmedicine.anatomical_structure030220 oncology & carcinogenesisRadiological weapon030211 gastroenterology & hepatologySurgerybusinessPOSTOPERATIVE CHEMORADIOTHERAPYMRIAnnals of Surgery
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