Search results for "Self-Assembly"

showing 10 items of 438 documents

Stabilization of unilamellar catanionic vesicles induced by β-cyclodextrins: A strategy for a tunable drug delivery depot.

2018

The limited stability of catanionic vesicles has discouraged their wide use for encapsulation and controlled release of active substances. Their structure can easily break down to form lamellar phases, micelles or rearrange into multilamellar vesicles, as a consequence of small changes in their composition. However, despite the limited stability, catanionic vesicles possess an attractive architecture, which is able to efficiently encapsulate both hydrophobic and hydrophilic molecules. Therefore, improving the stability of the vesicles, as well as the control on unilamellar structures, are prerequisites for their wider application range. This study focuses on the impact of β-cyclodextrins fo…

3003DepotPharmaceutical Science02 engineering and technology010402 general chemistry01 natural sciencesMicelleDiffusionSurface-Active AgentsDrug Delivery SystemsCyclodextrinLamellar structureUnilamellar Liposomeschemistry.chemical_classificationCatanionic vesiclesCyclodextrinChemistryCetrimoniumVesiclebeta-Cyclodextrinstechnology industry and agricultureTemperatureSodium Dodecyl SulfateCatanionic vesicles; Cyclodextrin; Diffusion; NMR; Self-assembly; 3003Self-assembly021001 nanoscience & nanotechnologyCatanionic vesicleControlled releaseNMR0104 chemical sciencesChemical engineeringSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoDrug deliveryCetrimonium Compoundslipids (amino acids peptides and proteins)Self-assembly0210 nano-technologyInternational journal of pharmaceutics
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Buildup of Ultrathin Multilayer Films by a Self-Assembly Process: II. Consecutive Adsorption of Anionic and Cationic Bipolar Amphiphiles and Polyelec…

1991

We have recently reported on the consecutive physisorption of anionic and cationic bipolar amphiphiles onto charged surfaces, adsorbed out of aqueous solutions [1]. Here, we extend our previous concept to multipolar compounds such as polyelectrolytes. In contrast to the bipolar amphiphile system, it is not necessary to separate single charges by a rigid unit, when the polyelectrolyte is adsorbed from sufficiently concentrated solutions. In this case the physisorbed layer does not bind with all ionic groups to the surface and exposes free ionic groups at the new film/solution interface. Therefore a polyelectrolyte layer can replace a layer of bipolar amphiphiles in the consecutive buildup of…

AdsorptionAqueous solutionMaterials scienceChemical engineeringGeneral Chemical EngineeringMonolayerAmphiphileIonic bondingNanotechnologySurface chargeSelf-assemblyPolyelectrolyteBerichte der Bunsengesellschaft für physikalische Chemie
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Self-assembly of colloidal micelles in microfluidic channels.

2016

The self-assembly of amphiphilic Janus colloids in microfluidic channels is studied using hybrid molecular dynamics simulations with fully resolved hydrodynamic interactions incorporated through the multi-particle collision dynamics algorithm. The simulations are conducted at a density and temperature where the Janus particles spontaneously self-assemble into spherical micelles to minimize the interface between the solvophobic caps and the surrounding solvent. In confined systems, this contact area can also be reduced by aggregation at the channel walls. Indeed, a sizable fraction of free particles and small clusters with three and four members are found at the walls when the microfluidic c…

Aggregation numberChemistryJanus particlesNanotechnology02 engineering and technologyGeneral Chemistry010402 general chemistry021001 nanoscience & nanotechnologyCondensed Matter PhysicsHagen–Poiseuille equation01 natural sciencesMicelle0104 chemical sciencesMolecular dynamicsChemical physicsSelf-assemblyJanus0210 nano-technologySolvophobicSoft matter
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Surfactant self-assembling in gas phase: electrospray ionization- and matrix-assisted laser desorption/ionization-mass spectrometry of singly charged…

2005

The self-assembling of sodium bis (2-ethylhexyl) sulfosuccinate (AOT) in gas phase has been investigated by electrospray ionization- and matrix-assisted laser desorption/ionization mass spectrometry. Large surfactant clusters with an aggregation number close to that found in apolar media have been observed either as positive or negative ions. Moreover, the marked predominance of singly charged species as well as preliminary theoretical calculations strongly suggest an aggregate structure characterized by an internal hydrophilic core hosting the extra charge surrounded by an apolar shell constituted by the surfactant alkyl chains. This structure is similar to that of the more familiar revers…

Aggregation numberChemistrygas-phase self-assemblyElectrospray ionizationsurfactantESI-MS and ESI-MS/MSAnalytical chemistryMass spectrometryMicelleMALDI-MSIonMatrix-assisted laser desorption/ionizationPulmonary surfactantIonizationSpectroscopyJournal of mass spectrometry : JMS
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Organized assemblies of magnetic clusters

2003

Abstract In this work we have explored the possibilities to create layered organizations of the Mn 12 single-molecule magnets using the Langmuir–Blodgett technique or attaching these clusters onto a metal surface by preparing self-assembled monolayers (SAMs). In the first part we discuss the use of the Langmuir–Blodgett (LB) technique in order to obtain organized magnetic films formed by monolayers of these clusters. Two strategies have been used with this aim. The first one consists of mixing Mn 12 acetate or benzoate derivatives with an amphiphile, while the second procedure is based on the use of Mn 12 derivatives specifically designed to form LB films. An alternative method is that of p…

Alternative methodsCrystallographyChemistryGeneral Chemical EngineeringAmphiphileMonolayerNanotechnologyMagnetic filmsSelf-assembled monolayerGeneral ChemistrySelf-assemblyMolecular materialsLangmuir–Blodgett filmComptes Rendus Chimie
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How self-assembly of amphiphilic molecules can generate complexity in the nanoscale

2015

Abstract Given the importance of nanomaterials and nanostructures in modern technology, in the past decades much effort has been directed to set up efficient bottom up protocols for the piloted self-assembly of molecules. However, molecules are generally disinclined to adopt the desired structural organization because they behave according to their own specific intermolecular interactions. Thus, only some selected classes of chemical compounds are capable to lead to useful self-assembled structures. Amphiphiles, simultaneously possessing polar and apolar moieties within their molecular architecture, can give a wide scenario of possible intermolecular interactions: polar–polar, polar–apolar,…

Amphiphilic moleculeNanostructureStructural organizationChemistryNanomachinesNanotechnologyTop-down and bottom-up designLiving cellComplexitySelf-assemblyNanodevicesNanomachinesSelf-assemblyComplexityNanotechnologyColloid and Surface ChemistryNanotechnologySelf-assemblyNanodevices
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Self-assembly of 3,5-bis(ethoxycarbonyl)pyrazolate anions and ammonium cations of β-phenylethylamine or homoveratrylamine into hetero-double-stranded…

2009

Hydrogen-bonded double-stranded hetero-helices are formed when reacting sodium 3,5-bis(ethoxycarbonyl)pyrazolate with beta-phenethylammonium or homoveratrylammonium chloride, in which one of the strands is defined by the ammonium cations and the other one by the pyrazolate anions.

AnionsCircular DichroismSodiumOrganic Chemistrychemistry.chemical_elementHydrogen BondingCrystallography X-RayBiochemistryChlorideProtein Structure SecondaryQuaternary Ammonium Compoundschemistry.chemical_compoundchemistryPhenethylaminesPolymer chemistrymedicineOrganic chemistryAmmoniumSelf-assemblyBeta-PhenylethylaminePhysical and Theoretical ChemistryDouble strandedmedicine.drugOrganic & Biomolecular Chemistry
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Ion-Pairing Effects in the Self-Assembly of a Fluorescent Pseudorotaxane

2006

Herein we report on the self-assembly, in a low polarity solvent, of a pseudorotaxane species comprising binaphthyl-26-crown-8 (BN26C8) as the macrocyclic host and anthracenyl-benzylammonium as the threadlike positively charged guest (ABH+). Absorption and luminescence data reveal a very efficient energy transfer process occurring from the binaphthyl to the anthracene singlet excited states. The self-assembly is highly dependent on the nature of the counteranion confirming the crucial role played by it in the competition between the self-assembly process and the formation of ion pairs (ABH+X-). This behavior can be readily evidenced in dilute solutions from the analysis of the luminescence …

AnthraceneIon pairsRotaxanesPhotochemistryStereochemistryOrganic ChemistrySupramolecular chemistrySelf-assemblychemistry.chemical_compoundCrystallographyTRISPHATMolecular recognitionchemistryHexafluorophosphateddc:540Proton NMRSinglet stateMolecular recognitionPhysical and Theoretical ChemistryLuminescenceEuropean Journal of Organic Chemistry
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Self-assembly of 1- and 2-Dimensional Multicompartmental Arrays via the 2-Aminopyrimidine H-Bonding Motif and Selective Guest Inclusion

2000

Abstract The H-bond mediated self-assembly of aminopyrimidine substituted anthracene derivatives 4 and 5, respectively, generate 1- and 2-dimensional multicompartmental arrays in the solid state as revealed by X-ray crystallographic analysis. The derived ‘pigeon-hole’ lattice is defined by syn-coplanar positioning of anthracene moieties at a distance of ca. 7 A, allowing the formation of selective clathrate-type inclusion entities with guests of appropriate shape and size, in particular phenazine, which presents both structural and interactional complementarity. These data provide insight into the interplay of the different structural and interactional features of the molecular components t…

AnthraceneStereochemistryHydrogen bondOrganic ChemistryPhenazineSupramolecular chemistrySolid-stateCrystal engineeringBiochemistrychemistry.chemical_compoundCrystallographychemistryDrug DiscoverySelf-assemblyTetrahedron
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Supramolecular Antioxidant Assemblies of Hyperbranched Polyglycerols and Phenols

2014

AntioxidantPolymers and Plasticsmedicine.medical_treatmentOrganic ChemistrySupramolecular chemistryCondensed Matter Physicschemistry.chemical_compoundchemistryPolymer chemistryMaterials ChemistrymedicineOrganic chemistryPhenolsSelf-assemblyPhysical and Theoretical ChemistryMacromolecular Chemistry and Physics
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