Search results for "Self-healing hydrogels"

Poly(N-isopropylacrylamide) and Copolymers: A Review on Recent Progresses in Biomedical Applications.

2017

The innate ability of poly(N-isopropylacrylamide) (PNIPAAm) thermo-responsive hydrogel to copolymerize and to graft synthetic polymers and biomolecules, in conjunction with the highly controlled methods of radical polymerization which are now available, have expedited the widespread number of papers published in the last decade—especially in the biomedical field. Therefore, PNIPAAm-based hydrogels are extensively investigated for applications on the controlled delivery of active molecules, in self-healing materials, tissue engineering, regenerative medicine, or in the smart encapsulation of cells. The most promising polymers for biodegradability enhancement of PNIPAAm hydrogels are probably…

E-beam irradiation and UV photocrosslinking of microemulsion-laden poly(N-vinyl-2-pyrrolidone) hydrogels for ‘‘in situ’’ encapsulation of volatile hy…

2011

Gelled microemulsions are the subject of considerable scientific and commercial interest. Many efforts are currently devoted to improving their toxicological profile and functioning as biocompatible diffusion barrier for the controlled delivery of hydrophobic compounds. In the present investigation, a non-ionic polymeric surfactant was chosen to generate an oil-in-water microemulsion of a model fragrance in the presence of poly(N-vinyl-2-pyrrolidone) (PVP). The microemulsion was then subjected to either electron-beam or UV-irradiation to induce free-radical crosslinking of PVP at low temperature and in the absence of crosslinking agents, catalysts and initiators. Irradiation conditions with…

Dynamic Model Metallo‐Supramolecular Dual‐Network Hydrogels with Independently Tunable Network Crosslinks

2020

Hydrogel films engineered in a mesoscopically ordered structure and responsive to ethanol vapors

2014

Abstract Responsive hydrogels filling the interstitial spaces of photonic crystals can form mesoscopically structured materials, which exhibit reversible shifts in the Bragg diffracted light as a response of environmental changes. These materials can be used to generate chemical or biochemical sensors. The present work reports on the synthesis and characterization of ethanol responsive hydrogels that can be used in the design of novel breathalyzers. The dynamic mechanical behavior of the macroscopic hydrogels and their swelling features in the presence of different liquids or vapors have been investigated to orientate the choice of the best responsive material and curing process. The swelli…

Smart hydrogels for novel optical functions

2007

Nanocomposites of inherently conductive polyaniline (PANT) within a highly hydrophilic polyvinyl alcohol (PVA) based hydrogel have been produced by coupling a conventional dispersion chemical oxidative polymerization to a subsequent high energy irradiation step, in order to convert the polymer stabilizing the aqueous dispersion, namely the PVA, into a highly water swollen hydrogel incorporating the PANT particles. The incorporation of the electroactive and "pH-sensitive" polymer into a transparent and highly permeable hydrogel matrix has been pursued as a route to the development of a novel class of potentially biocompatible, smart hydrogels that can respond to changes of the surrounding en…

Connectivity Defects and Collective Assemblies in Model Metallo‐Supramolecular Dual‐Network Hydrogels

2019

Reversible Modulation of Elasticity in Fluoroazobenzene-Containing Hydrogels Using Green and Blue Light.

2017

Hydrogels are soft materials that have found multiple applications in biomedicine and represent a good platform for the introduction of molecular switches and synthetic machines into macromolecular networks. Tuning their mechanical properties reversibly with light is appealing for a variety of advanced applications and has been demonstrated in the past; however, their activation typically requires the use of UV light, which displays several drawbacks related to its damaging character and limited penetration in tissues and materials. This study circumvents this limitation by introducing all-visible ortho-fluoroazobenzene switches into a hydrophilic network, which, as a result, can be activat…

Energy Consumption for the Desalination of Salt Water Using Polyelectrolyte Hydrogels as the Separation Agent

2017

The energy consumption for a novel desalination approach using charged hydrogels under externally applied pressure is experimentally measured and calculated. The salt separation is based on a partial rejection of mobile salt ions caused by the fixed charges inside the polyelectrolyte network. Self-synthesized and commercial poly(acrylic acid) hydrogels are used to study the desalination performance in reference to sodium chloride solutions within the concentration range of 0.1–35 g L−1. The influence of various synthetic parameters, such as the degree of crosslinking (DC) and the size and shape of the particles, is investigated. Furthermore, the effect of process parameters including the am…

Micro- to Nanoscale Bio-Hybrid Hydrogels Engineered by Ionizing Radiation

2021

Bio-hybrid hydrogels consist of a water-swollen hydrophilic polymer network encapsulating or conjugating single biomolecules, or larger and more complex biological constructs like whole cells. By modulating at least one dimension of the hydrogel system at the micro- or nanoscale, the activity of the biological component can be extremely upgraded with clear advantages for the development of therapeutic or diagnostic micro- and nano-devices. Gamma or e-beam irradiation of polymers allow a good control of the chemistry at the micro-/nanoscale with minimal recourse to toxic reactants and solvents. Another potential advantage is to obtain simultaneous sterilization when the absorbed doses are wi…

Equivalences between refractive index and equilibrium water content of conventional and silicone hydrogel soft contact lenses from automated and manu…

2007

PURPOSE: The purpose of the present study was to develop mathematical relationships that allow obtaining equilibrium water content and refractive index of conventional and silicone hydrogel soft contact lenses from refractive index measures obtained with automated refractometry or equilibrium water content measures derived from manual refractometry, respectively. METHODS: Twelve HEMA-based hydrogels of different hydration and four siloxane-based polymers were assayed. A manual refractometer and a digital refractometer were used. Polynomial models obtained from the sucrose curves of equilibrium water content against refractive index and vice-versa were used either considering the whole range…