Search results for "Senso"
showing 10 items of 4750 documents
Index-based triangulation method for efficient generation of large three-dimensional ultrasonic C-scans
2018
The demand for high-speed ultrasonic scanning of large and complex components is driven by a desire to reduce production bottlenecks during the non-destructive evaluation (NDE) of critical parts. Emerging systems (including robotic inspection) allow for the collection of large volumes of data in short time spans, compared to existing inspection systems. To maximise throughput, it is crucial that the reconstructed inspection datasets are generated and evaluated rapidly without loss of detail. This requires new data visualisation and analysis tools capable of mapping complex geometries while guaranteeing full coverage. This paper presents an entirely new approach for the visualisation of thre…
Decreasing dietary linoleic acid promotes long chain omega-3 fatty acid incorporation into rat retina and modifies gene expression
2011
International audience; Age-related macular degeneration (AMD) may be partially prevented by dietary habits privileging the consumption of ω3 long chain polyunsaturated fatty acids (ω3s) while lowering linoleic acid (LA) intake. The present study aimed to document whether following these epidemiological guidelines would enrich the neurosensory retina and RPE with ω3s and modulate gene expression in the neurosensory retina. Rat progenitors and pups were fed with diets containing low or high LA, and low or high ω3s. After scotopic single flash and 8-Hz-Flicker electroretinography, rat pups were euthanized at adulthood. The fatty acid profile of the neurosensory retina, RPE, liver, adipose tis…
Oro-gustatory perception of dietary lipids and calcium signaling in taste bud cells are altered in nutritionally obesity-prone Psammomys obesus.
2013
Since the increasing prevalence of obesity is one of the major health problems of the modern era, understanding the mechanisms of oro-gustatory detection of dietary fat is critical for the prevention and treatment of obesity. We have conducted the present study on Psammomys obesus, the rodent desert gerbil which is a unique polygenic natural animal model of obesity. Our results show that obese animals exhibit a strong preference for lipid solutions in a two-bottle test. Interestingly, the expression of CD36, a lipido-receptor, in taste buds cells (TBC), isolated from circumvallate papillae, was decreased at mRNA level, but remained unaltered at protein level, in obese animals. We further st…
The Lipid-Sensor Candidates CD36 and GPR120 Are Differentially Regulated by Dietary Lipids in Mouse Taste Buds: Impact on Spontaneous Fat Preference
2011
BACKGROUND: Recent studies in rodents and humans suggest that the chemoreception of long-chain fatty acids (LCFA) in oral cavity is involved in the spontaneous preference for fatty foods and might contribute to the obesity risk. CD36 and GPR120 are LCFA receptors identified in rodent taste bud cells. The fact that CD36 or GPR120 gene inactivation leads to a decrease in the preference for lipids raises the question of the respective role(s) played by these gustatory lipid-sensor candidates. METHODOLOGY/PRINCIPAL FINDINGS: Using a combination of biochemical, nutritional and behavioural studies in wild-type, CD36(+/-)and CD36(-/-) mice, it was found that: 1°) CD36 and GPR120 display different …
Oro-sensory perception of dietary lipids: new insights into the fat taste transduction.
2009
The sense of taste informs the organism about the quality of ingested food. Five basic taste modalities, e.g., sweet, sour, bitter, salty and umami have so far been identified. Recent compelling evidence from rodent and human studies raise the possibility for an additional sixth taste modality devoted to the perception of lipids. Recent studies strongly suggest that lingual CD36, being implicated in the perception of dietary fat, may act as a gustatory lipid sensor. Knocking down of CD36 gene decreases the spontaneous preference for long chain fatty acids (LCFA) in mice subjected to a free choice situation. Lingual CD36, after activation by LCFA, is able to trigger specific signalling mecha…
Data Compression Approach for Long-Term Monitoring of Pavement Structures
2019
Pavement structures are designed to withstand continuous damage during their design life. Damage starts as soon as the pavement is open to traffic and increases with time. If maintenance activities are not considered in the initial design or considered but not applied during the service life, damage will grow to a point where rehabilitation may be the only and most expensive option left. In order to monitor the evolution of damage and its severity in pavement structures, a novel data compression approach based on cumulative measurements from a piezoelectric sensor is presented in this paper. Specifically, the piezoelectric sensor uses a thin film of polyvinylidene fluoride to sense the ener…
3D Integration : towards high-performance innovative imaging sensors
2017
Nowadays, CMOS image sensors are almost exclusively architectured around analog pixels. A transition to purely digital pixels would significantly improve the performances of imagers. Unfortunately, such an approach is difficult to consider because it causes an oversized and unusable pixel for the consumer market. One of the promising ways to solve this problem of pixel integration is to think not only in 2D dimensions, but in 3D dimensions by distributing the different functionalities on several interconnected wafers.Thus, the work presented in this manuscript describes the design of a purely digital image sensor in CMOS 3D-IC 130 nm Tezzaron technology. This sensor is architectured around …
A low power interface circuit design for a CMOS based smart optical sensor
2012
In this paper, a CMOS interface circuit as part of an optical sensor-based microsystem for pH monitoring applications is presented. The proposed circuit is capable of processing a voltage signal produced by the light transducer and generating 8-bit digital outputs representing the color information (i.e. wavelength). A resolution of 8 different colors has been achieved as a proof of concept and can easily be extended to a higher number of colors without a major modification in the architecture. The proposed interface circuit is a mixed-signal solution that consists of analog as well as digital building blocks along with a light transducer. It can be used as a portable and non-intrusive opti…
ALICE forward rapidity upgrades
2017
Two forward rapidity upgrades of the ALICE apparatus at the LHC are presented: the Muon Forward Tracker (MFT) and the Fast Interaction Trigger (FIT). Their designs are driven by physics performance studies, which have been done using MC simulations. Several prototypes have been tested. Currently the detector design phase has ended. The final layouts, geometries and expected performance figures are presented. The latest developments from the test of the prototypes are discussed. The MFT will improve the performance of the ALICE Muon Spectrometer by adding vertexing capabilities to the system. The elementary component of the MFT is a Monolithic Active Pixel Sensor (MAPS), using the TowerJazz …
Update on the TowerJazz CMOS DMAPS development for the ATLAS ITk
2019
The upgrade of the ATLAS tracking detector for the High-Luminosity Large Hadron Collider at CERN requires the development of novel radiation hard silicon sensor technologies. For the de- velopment of depleted CMOS sensors for ATLAS we combined small electrodes with minimal capacitance and advanced processing for fully depleted active sensor volume to achieve radiation hard CMOS sensors in line with ATLAS ITk specifications. Based on initial studies on the prototype sensor “TowerJazz Investigator” we have now developed, produced and tested a first full-size depleted CMOS sensor based on the 180nm TowerJazz imag- ing process, the so-called “MALTA” sensor. The sensor combines special low-noise…