Search results for "Sensor"

showing 10 items of 4594 documents

Ocular pulse amplitude in patients with open angle glaucoma, normal tension glaucoma, and ocular hypertension.

2002

Intraocular pressure (IOP) is not a fixed constant value but rather has pulsatile components associated with cardiac action. The SmartLens dynamic observing tonometer (odc, Ophthalmic Development Company AG, Zurich, Switzerland) can measure and record simultaneously IOP and ocular pulse amplitude (OPA). It was the aim of this study to evaluate OPA in patients with primary open angle glaucoma (POAG) and high IOP, normal tension glaucoma (NTG), and ocular hypertension (OHT). Furthermore, the authors examined whether there were any correlations with blood pressure.80 subjects were divided into four groups (n=20): 20 patients each with POAG, NTG, and OHT and 20 volunteers without any ocular pat…

AdultMaleIntraocular pressuremedicine.medical_specialtyOpen angle glaucomagenetic structuresOcular PathologyOcular hypertensionGlaucomaBlood PressureCellular and Molecular NeuroscienceTonometry OcularOphthalmologyNormal tension glaucomaMedicineHumansIntraocular PressureAgedAged 80 and overbusiness.industryAge FactorsGlaucomaMiddle Agedmedicine.diseaseSensory Systemseye diseasesLow Tension GlaucomaOphthalmologyBlood pressureFemaleOcular Hypertensionsense organsbusinessGlaucoma Open-AngleScientific CorrespondenceThe British journal of ophthalmology
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Medium-term visual, refractive, and intraocular stability after implantation of a posterior chamber phakic intraocular lens to correct moderate to hi…

2011

To evaluate the medium-term refractive and visual outcomes and the complications after implantation of a silicone posterior chamber phakic intraocular lens (PC pIOL) for moderate to high myopia.Oftalmar, Medimar International Hospital, Alicante, Spain.Retrospective case series.Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, and intraocular pressure were evaluated during a medium-term follow-up. Postoperative complications were also studied.The study enrolled 35 eyes (mean preoperative spherical equivalent [SE] -10.25 diopters [D] ± 3.19 [SD]) of 20 patients with a mean age of 31.83 ± 8.87 years and a mean follow-up of 57.34 ± 9.24 months. The mean UDVA improved…

AdultMaleIntraocular pressuremedicine.medical_specialtyPhakic Intraocular LensesVisual acuitygenetic structuresVisual AcuityPhakic intraocular lensRefraction OcularMedium termYoung AdultPostoperative ComplicationsLens Implantation IntraocularOphthalmologyMedicineHumansDioptreIntraocular PressureRetrospective Studiesbusiness.industryHigh myopiaPosterior Eye SegmentMiddle AgedRefractioneye diseasesSensory SystemsPosterior chamber phakic intraocular lensOphthalmologyTreatment OutcomeMyopia DegenerativeSurgeryFemalemedicine.symptombusinessFollow-Up StudiesJournal of cataract and refractive surgery
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Healon5 versus Viscoat during cataract surgery: intraocular pressure, laser flare and corneal changes

2000

Background: The use of a viscoelastic substance facilitates cataract surgery. Healon 5 is a new viscoelastic product with special rheological properties. We evaluated the postoperative effect of Viscoat and Healon5 on intraocular pressure (IOP), central corneal thickness (CCT), endothelial cell counts and laser flare. Methods: Forty-eight eyes of 48 patients undergoing routine phacoemulsification followed by foldable IOL implantation were enrolled. Either Healon5 or Viscoat was used according to a block- randomization scheme. The aspiration technique was standardized. IOP, CCT, endothelial cell counts and laser flare were compared pre- and postoperatively. Statistical analysis was performed…

AdultMaleIntraocular pressuremedicine.medical_specialtyRandomizationgenetic structuresmedicine.medical_treatmentEye diseaseCell CountIntraocular lensAqueous HumorPhotometryCellular and Molecular NeuroscienceLens Implantation IntraocularCorneaOphthalmologymedicineHumansProspective StudiesHyaluronic AcidIntraocular PressurePhacoemulsificationbusiness.industryChondroitin SulfatesEndothelium CornealPhacoemulsificationCataract surgerymedicine.diseaseeye diseasesSensory SystemsDrug CombinationsOphthalmologymedicine.anatomical_structureQuartileFemalesense organsbusinessChondroitinGraefe's Archive for Clinical and Experimental Ophthalmology
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Intraocular pressure after excimer laser myopic refractive surgery

2001

The aim of this study was to determine whether intraocular pressure (IOP), as measured by Goldmann applanation or non-contact tonometry, shows systematic changes in patients who have undergone photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK). IOP was measured by central Goldmann and non-contact tonometry in 54 patients pre and post-PRK, and in 43 patients pre- and post-LASIK. An interval of 12 months was allowed after surgery. Patients were selected to have one of four specific initial values of refractive error (-2.5, -5.0, -7.5 and -10.0 D). Fellow unoperated eyes were used as controls. A paired Student's t-test and a one-way ANOVA test were used for statistical a…

AdultMaleIntraocular pressuremedicine.medical_specialtyRefractive errorgenetic structuresmedicine.medical_treatmentEye diseaseKeratomileusis Laser In SituContext (language use)KeratomileusisPhotorefractive KeratectomySensitivity and SpecificityTonometry OcularRefractive surgeryOphthalmologyMyopiamedicineHumansIntraocular PressureAnalysis of Variancebusiness.industryLASIKmedicine.diseaseeye diseasesSensory SystemsPhotorefractive keratectomySurgeryOphthalmologyFemaleLasers Excimersense organsbusinessOptometryOphthalmic and Physiological Optics
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Risk factors of ocular hypertension and glaucoma. The Casteldaccia Eye Study.

1994

A case-control study was planned as a part of the Casteldaccia Eye Study in order to investigate about risk factors of ocular hypertension and glaucoma. Cases were 44 subjects with glaucoma or intraocular pressure of 24 mm Hg or more. Controls were 220 subjects with intraocular pressure of 20 mm Hg or less and no signs of glaucoma. A number of environmental, behavioral, systemic and ocular variables were studied. Among the others we investigated the following: sunlight exposure, smoking, alcohol intake, pregnancies, systemic hypertension, diabetes, use of corticosteroids, refractive status, anterior chamber depth, lens nuclear sclerosis, iris color and texture. After univariate analysis the…

AdultMaleIntraocular pressuremedicine.medical_specialtygenetic structuresEye diseaseOcular hypertensionGlaucomaRisk FactorsPhysiology (medical)OphthalmologymedicineHumansRisk factorIntraocular PressureAgedAged 80 and overNuclear sclerosisbusiness.industryCase-control studyOdds ratioMiddle Agedmedicine.diseaseeye diseasesSensory SystemsOphthalmologyItalyCase-Control StudiesChronic DiseaseFemaleOcular Hypertensionsense organsbusinessGlaucoma Open-AngleDocumenta ophthalmologica. Advances in ophthalmology
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Intraocular pressure after small incision cataract surgery: temporal sclerocorneal versus clear corneal incision.

2001

To compare intraocular pressure (IOP) after phacoemulsification and foldable intraocular lens (IOL) implantation using a temporal sclerocorneal or clear corneal incision.Department of Ophthalmology, Johannes Gutenberg-University, Mainz, Germany.One hundred patients (100 eyes) with cataract having phacoemulsification with posterior chamber IOL implantation were randomly assigned to receive a temporal sclerocorneal or clear corneal tunnel incision. Intraocular pressure was measured preoperatively and 6 hours, 1, 2, and 3 days, and 5 months postoperatively. Statistical significance was determined by nonparametric group comparisons using 2-sample random Wilcoxon tests.Six hours postoperatively,…

AdultMaleIntraocular pressuremedicine.medical_specialtygenetic structuresmedicine.medical_treatmentIntraocular lensCataractCorneaLens Implantation IntraocularCorneaOphthalmologymedicineHumansMinimally Invasive Surgical ProceduresProspective StudiesSclerocorneaIntraocular PressureAgedAged 80 and overPhacoemulsificationbusiness.industryPhacoemulsificationCataract surgeryMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryScleraOphthalmologymedicine.anatomical_structureSurgeryFemalesense organsbusinessSurgical incisionScleraJournal of cataract and refractive surgery
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Falsely elevated intraocular pressure due to increased central corneal thickness

1999

PURPOSE: To evaluate whether ocular hypertensive subjects have a higher central corneal thickness than other individuals. METHODS: In this prospective study, 48 subjects with ocular hypertension, 63 patients with open-angle glaucoma, 56 nonglaucomatous patients with diabetes mellitus, and 106 control subjects were evaluated. Corneal thickness was measured by ultrasound pachymetry, and intraocular pressure was determined by Goldmann applanation tonometry. RESULTS: Central corneal thickness was significantly higher in the ocular hypertensive subjects, mean +/- S.D., 592+/-39 microm, than in the patients with glaucoma (536+/-34 microm), the nonglaucomatous patients with diabetes mellitus (550+…

AdultMaleIntraocular pressuremedicine.medical_specialtyprimary open-angle glaucomaAdolescentgenetic structuresEye diseaseOcular hypertensionGlaucomaCorneaCellular and Molecular NeurosciencePredictive Value of TestsCorneaOphthalmologyDiabetes mellitusHumansMedicineFalse Positive ReactionsProspective StudiesCorneal pachymetry[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory OrgansProspective cohort studyAgedUltrasonographyAged 80 and overmedicine.diagnostic_testdiabetesbusiness.industryMiddle Agedmedicine.diseaseSensory Systemseye diseasesSurgeryOphthalmologymedicine.anatomical_structureocular hypertensionFemalecentral corneal thicknesssense organsbusinessGlaucoma Open-Angle[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyintraocular pressure
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KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome

2015

Background Joubert syndrome (JBTS) and related disorders are defined by cerebellar malformation (molar tooth sign), together with neurological symptoms of variable expressivity. The ciliary basis of Joubert syndrome related disorders frequently extends the phenotype to tissues such as the eye, kidney, skeleton and craniofacial structures. Results Using autozygome and exome analyses, we identified a null mutation in KIAA0556 in a multiplex consanguineous family with hallmark features of mild Joubert syndrome. Patient-derived fibroblasts displayed reduced ciliogenesis potential and abnormally elongated cilia. Investigation of disease pathophysiology revealed that Kiaa0556-/- null mice possess…

AdultMaleK04F10.2KIAA0556MicrotubuleMicrotubulesRetinaMiceJoubert syndromeCerebellumAnimalsHumansAbnormalities MultipleExomeCiliaEye AbnormalitiesSensory disorders Radboud Institute for Molecular Life Sciences [Radboudumc 12]Caenorhabditis elegansChildCells CulturedAdenosine TriphosphatasesADP-Ribosylation FactorsResearchBrainMetabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6]Kidney Diseases CysticBasal BodiesPedigreeMice Inbred C57BLRenal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11]Basal bodyChild PreschoolMutationFemaleKataninMicrotubule-Associated ProteinsProtein BindingGenome Biology
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Intrastromal corneal ring segment implantation in paracentral keratoconus with coincident topographic and coma axis.

2012

To evaluate the efficacy, predictability, and safety of implantation of Ferrara-type intrastromal corneal ring segments (ICRS) for refractive correction of paracentral keratoconus.Fernández-Vega Ophthalmological Institute, Oviedo, Spain.Cohort study.Snellen uncorrected (UDVA) and corrected (CDVA) distance visual acuities and residual refractive errors were recorded before and 6 months after ICRS implantation for keratoconus. The tunnels for ICRS implantation were created with a femtosecond laser. The power vector and the Alpins method were used to analyze postoperative refractive outcomes.The study evaluated 56 eyes of 49 patients. The mean UDVA was 0.17 ± 0.14 (SD) preoperatively and 0.41 …

AdultMaleKeratoconusmedicine.medical_specialtygenetic structuresmedicine.medical_treatmentCorneal StromaVision DisordersVisual AcuityComa (optics)Power vectorKeratoconusRefraction OcularCohort StudiesProsthesis ImplantationYoung AdultOphthalmologymedicineHumansPolymethyl MethacrylateProspective StudiesAlpins methodAgedIntrastromal corneal ring segmentbusiness.industryCorneal TopographyProstheses and ImplantsMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologySurgeryFemalesense organsLaser TherapyCorneal ringbusinessJournal of cataract and refractive surgery
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Amplitudes of laser evoked potential recorded from primary somatosensory, parasylvian and medial frontal cortex are graded with stimulus intensity

2003

Intensity encoding of painful stimuli in many brain regions has been suggested by imaging studies which cannot measure electrical activity of the brain directly. We have now examined the effect of laser stimulus intensity (three energy levels) on laser evoked potentials (LEPs) recorded directly from the human primary somatosensory (SI), parasylvian, and medial frontal cortical surfaces through subdural electrodes implanted for surgical treatment of medically intractable epilepsy. LEP N2* (early exogenous/stimulus-related potential) and LEP P2** (later endogenous potential) amplitudes were significantly related to the laser energy levels in all regions, although differences between regions w…

AdultMaleLaser-Evoked PotentialsPainStimulus (physiology)Somatosensory systemFunctional LateralityNuclear magnetic resonanceSeizuresReaction TimemedicineNoxious stimulusHumansEvoked potentialElectrodesEvoked PotentialsAnterior cingulate cortexPain MeasurementBrain MappingChemistryLasersDose-Response Relationship RadiationSomatosensory CortexMiddle AgedFrontal LobeElectrophysiologyAnesthesiology and Pain Medicinemedicine.anatomical_structureNeurologySomatosensory evoked potentialFemaleNeurology (clinical)NeurosciencePain
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