Search results for "Sensory Systems"

showing 10 items of 793 documents

A randomized trial of intravitreal bevacizumab vs. ranibizumab for myopic CNV.

2014

AIMS: The aim was to compare the efficacy of intravitreal therapy with bevacizumab and ranibizumab for choroidal neovascularization (CNV) in pathologic myopia (PM). METHODS: This was a prospective multicenter randomized nonblinded trial. RESULTS: In seven centers, 78 eyes were randomized 1:1 to treatment with bevacizumab (group B, 40 eyes) or ranibizumab (group R, 38 eyes) given with an "on demand" regimen (PRN). The mean follow-up was 19 months (SD 2, range 12-24). The mean BCVA at baseline was 0.60 logMAR (20/80 Snellen equivalent, Seq) and 50 letter score (ls). Mean final BCVA was 0.51 LogMAR (20/63 Seq) and 57 ls (p = 0.0009 and p = 0.0002, respectively). In group B, mean basal BCVA was…

MaleVascular Endothelial Growth Factor AVisual Acuity/drug effectsVisual acuitygenetic structuresVisual AcuityAngiogenesis Inhibitorslaw.inventionBevacizumab/therapeutic use0302 clinical medicineRandomized controlled triallawMyopiaMedicineProspective StudiesProspective cohort studyPathological myopiaAged 80 and overMiddle AgedSensory SystemsBevacizumabVascular endothelial growth factor AChoroidal neovascularizationIntravitreal InjectionsMyopia DegenerativeFemalemedicine.symptommedicine.drugAdultmedicine.medical_specialtyBevacizumabNeuroscience(all)CNVBevacizumab; CNV; Pathological myopia; Ranibizumab.Antibodies Monoclonal HumanizedRanibizumab/therapeutic use03 medical and health sciencesCellular and Molecular NeuroscienceOphthalmologyRanibizumabVascular Endothelial Growth Factor A/antagonists & inhibitorsHumansAngiogenesis Inhibitors/therapeutic useIntravitreal bevacizumabAgedpathological myopia CNV bevacizumab ranibizumabSettore MED/30 - Malattie Apparato Visivobusiness.industryTherapeutic effectChoroidal Neovascularization/drug therapyeye diseasesChoroidal NeovascularizationOphthalmologyRegimen030221 ophthalmology & optometryMyopia Degenerative/drug therapysense organsRanibizumabbusiness030217 neurology & neurosurgeryFollow-Up StudiesGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
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RESOLVING AMBIGUITIES IN ORIENTATION, MOTION, AND DEPTH DOMAINS

1992

Three different perceptual systems—orientation, motion, and depth—can recover a global perceptual organization from spatially correlated random multielement patterns. In all three cases the global structure composed of random elements is evaluated by mechanisms performing measurements in the energy domain within appropriately defined local space—time areas. The selective increase in energy of one fraction of the elements may dramatically change the whole perceptual organization of the stimulus. In specially devised patterns one and the same element can belong to two or more separate perceptual organizations, the perceptual salience of one of which can be reinforced by a luminance increment…

MaleVision Disparitymedia_common.quotation_subjectDecision MakingExperimental and Cognitive PsychologyStimulus (physiology)Luminance050105 experimental psychologyMotion03 medical and health sciences0302 clinical medicineArtificial IntelligenceOrientationPerceptionHumans0501 psychology and cognitive sciencesGlobal structuremedia_commonDepth PerceptionCommunicationbusiness.industry05 social sciencesSpace perceptionPattern recognitionAmbiguityPerceptual salienceSensory SystemsOphthalmologyPattern Recognition VisualStimulus luminanceSpace PerceptionVisual PerceptionFemaleArtificial intelligencebusinessPsychology030217 neurology & neurosurgery
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Is Ranibizumab effective in stopping the loss of vision for Choroidal Neovascularization in Pathologic Myopia? A Long Term Follow-up Study

2010

Aim To assess the efficacy and safety of ranibizumab in the treatment of choroidal neovascularisation (CNV) caused by pathologic myopia (PM). Design Prospective, multicentre, interventional case series. Methods 40 eyes of 39 consecutive patients with PM and CNV were treated with ‘on demand’ intravitreal injection of ranibizumab 0.5 mg. Final best corrected visual acuity (BCVA) and its change from baseline were the main outcome measures. Changes in optical coherence tomography (OCT) central retinal thickness (CRT) were a secondary outcome. Results Mean age was 53±13 years and mean refractive error –13.5±6.5 D. Median follow-up was 13.3±2 (range 12–18) months. Fifteen eyes (37.5%) had previou…

MaleVisual Acuity/drug effectsRefractive errorgenetic structuresEye diseaseVisual AcuityVision disorderProspective StudiesFluorescein AngiographyMedicine(all)Neovascularisationmedicine.diagnostic_testAntibodies MonoclonalDrugsDiabetic retinopathyMiddle AgedFluorescein angiographySensory SystemsChoroidal neovascularizationmedicine.anatomical_structureMyopia DegenerativeIntravitreal InjectionsFemaleMyopia Degenerative/complicationsmedicine.symptomTomography Optical Coherencemedicine.drugAdultmedicine.medical_specialtyAntibodies Monoclonal HumanizedAntibodies Monoclonal/administration & dosageCellular and Molecular NeuroscienceRanibizumabOphthalmologymedicineHumansAgedbusiness.industryChoroidChoroidal Neovascularization/drug therapyOff-Label Usemedicine.diseaseChoroidal Neovascularizationeye diseasesOphthalmologyChoroidsense organsRanibizumabaged 80 and overbusinessFollow-Up Studies
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Comparing oculomotor efficiency and visual attention between drivers and non-drivers through the Adult Developmental Eye Movement (ADEM) test: A visu…

2021

Objective The objective of this study was to assess and compare drivers’ and non-drivers’ outcomes in the Adult Developmental Eye Movement test (ADEM), a visual-verbal test that measures the time needed to read series of numbers in both a vertical and horizontal reading pattern. A set of driving parameters (i.e., experience, risk exposure, and day and night perceived difficulty) and demographic variables (i.e., age, gender, and academic level) were considered as potential predictors of the test performance. Methods For this cross-sectional study, 302 healthy subjects (age range 20 to 86 years old) completed a self-reported questionnaire aimed at retrieving data on the independent variables…

MaleVisual acuityEye MovementsLightVisionPhysiologyVisual SystemEpidemiologySensory PhysiologyVisual AcuitySocial SciencesAudiology0302 clinical medicineSociologyAtencióSurveys and QuestionnairesTask Performance and AnalysisMedicine and Health SciencesPsychologyAttentionmedia_commonVisual ImpairmentsAged 80 and overMultidisciplinary05 social sciencesQRMiddle AgedSensory SystemsTest (assessment)OftalmologíaMedicineSensory PerceptionFemalemedicine.symptomPsychologyResearch ArticleAdultAutomobile Drivingmedicine.medical_specialtymedia_common.quotation_subjectScienceEducationYoung Adult03 medical and health sciences0502 economics and businessLinear regressionmedicineOptometríaHumansVisual attentionVisióSet (psychology)Educational AttainmentNight VisionVision OcularAged050210 logistics & transportationVariablesCognitive PsychologyBiology and Life SciencesEye movementSaccadic maskingOphthalmologyCross-Sectional StudiesAge GroupsMedical Risk FactorsPeople and PlacesCognitive SciencePerceptionPopulation Groupings030217 neurology & neurosurgeryNeuroscience
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Visual function comparison of 2 aspheric multifocal intraocular lenses

2011

To compare visual function after bilateral implantation of the multifocal Lentis Mplus LS-312 with a nonrotational symmetrical design (copolymer aspheric) or the Acrysof Restor SN6AD1 +3.0 D (hybrid aspheric) intraocular lens (IOL).Fernández-Vega Ophthalmological Institute, Oviedo, Spain.Comparative case series.Six months postoperatively, corrected distance visual acuity (CDVA), distance-corrected near visual acuity (DCNVA), the defocus curve, and photopic and mesopic contrast sensitivity with and without glare were measured.The mean CDVA was 0.02 ± 0.06 (SD) with the copolymer aspheric IOL and -0.06 ± 0.05 logMAR with the hybrid aspheric IOL (P=.07) and the mean DCNVA, 0.10 ± 0.06 and -0.0…

MaleVisual acuityPseudophakiagenetic structuresMesopic visionmedicine.medical_treatmentmedia_common.quotation_subjectVisual AcuityIntraocular lensGlareContrast SensitivityLens Implantation IntraocularmedicineHumansContrast (vision)Prospective StudiesMathematicsmedia_commonLenses IntraocularPhacoemulsificationGlare (vision)Middle AgedMultifocal intraocular lenseye diseasesSensory SystemsOphthalmologyVisual functionOptometryFemaleSurgerysense organsmedicine.symptomPhotopic visionJournal of Cataract and Refractive Surgery
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Contrast sensitivity loss in the peripheral visual field following laser in situ keratomileusis.

2007

We report a case of contrast sensitivity loss in the peripheral visual field following laser in situ keratomileusis (LASIK). A 50-year-old white man was referred to us for differences in visual perception in the peripheral field between the right eye, which had had LASIK, and the left eye, which was emmetropic. Linear meridional static perimetry was carried out in the 0- to 180-degree meridian using a Goldmann perimeter to assess the peripheral perimetric thresholds. There was a statistically significantly marked increased threshold in contrast sensitivity in the nasal and temporal fields from 40 degrees of eccentricity in the LASIK eye compared with that in the emmetropic eye. Eyes treated…

MaleVisual acuitygenetic structuresEye diseasemedicine.medical_treatmentKeratomileusis Laser In SituVision DisordersVisual AcuityEmmetropiaKeratomileusisContrast SensitivityMedicineHumansmedicine.diagnostic_testbusiness.industryLASIKCorneal TopographyMiddle AgedCorneal topographymedicine.diseaseeye diseasesSensory SystemsVisual fieldOphthalmologyMeridian (perimetry visual field)OptometryVisual Field TestsSurgerysense organsmedicine.symptomVisual FieldsbusinessJournal of cataract and refractive surgery
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Correlation of pupil size with visual acuity and contrast sensitivity after implantation of an apodized diffractive intraocular lens

2007

To determine whether pupil size is correlated with visual acuity and contrast sensitivity at all distances in eyes with an apodized diffractive intraocular lens (IOL).Private Clinic, Oviedo, Spain.Six months after surgery, the best corrected distance visual acuity, best distance-corrected near visual acuity, intermediate visual acuity, and distance contrast sensitivity under photopic (85 cd/m2) and mesopic (5 cd/m2) conditions were measured in 670 eyes of 335 consecutive patients who had implantation of the AcrySof ReSTOR Natural IOL (SN60D3, Alcon). Pupil diameters in distance vision were measured using a pupillometer.The logMAR best corrected distance acuity was significantly better with …

MaleVisual acuitygenetic structuresMesopic visionmedia_common.quotation_subjectmedicine.medical_treatmentAcrylic ResinsVisual AcuityIntraocular lensProsthesis DesignPupilContrast SensitivityCorrelationLens Implantation IntraocularHumansMedicineContrast (vision)Prospective Studiesmedia_commonLenses Intraocularbusiness.industryPupilMiddle Agedeye diseasesSensory SystemsOphthalmologyOptometryFemaleSurgerysense organsSpatial frequencymedicine.symptombusinessPhotopic visionJournal of Cataract and Refractive Surgery
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Direct costs of glaucoma and severity of the disease: a multinational long term study of resource utilisation in Europe

2005

International audience; Background: Resource utilisation and direct costs associated with glaucoma progression in Europe are unknown. As population progressively ages, the economic impact of the disease will increase. Methods: From a total of 1655 consecutive cases, the records of 194 patients were selected and stratified by disease severity. Record selection was based on diagnoses of primary open angle glaucoma, glaucoma suspect, ocular hypertension, or normal tension glaucoma; 5 years minimum follow up were required. Glaucoma severity was assessed using a six stage glaucoma staging system based on static threshold visual field parameters. Resource utilisation data were abstracted from the…

Maleage distributionOrganes des sensgenetic structuresOffice VisitsOcular hypertensionGlaucomaDiseaseintraocular hypertensionSeverity of Illness IndexIndirect costs0302 clinical medicineambulatory careNormal tension glaucomamiddle agedopen angle glaucoma80 and overMedicine030212 general & internal medicinepathophysiologystatistical significanceAged 80 and overeducation.field_of_studyadultdisease coursearticlehealth care costclinical trialHealth Care Costshealth care planningSensory Systems3. Good healthEuropeagedfemalepriority journalstatisticsHealth Resourcesdisease severityadult; aged; article; disease course; disease severity; Europe; female; follow up; general practitioner; glaucoma; health care cost; health care utilization; human; intraocular hypertension; major clinical study; male; medical record; open angle glaucoma; priority journal; statistical significance; visual field; age distribution; ambulatory care; clinical trial; drug cost; economics; health care planning; hospitalization; middle aged; multicenter study; pathophysiology; sex ratio; statistics; utilization review; Adult; Age Distribution; Aged; Aged 80 and over; Drug Costs; Europe; Female; Follow-Up Studies; Glaucoma; Health Care Costs; Health Resources; Humans; Male; Middle Aged; Office Visits; Severity of Illness Index; Sex Distribution; Visual Fieldshospitalizationvisual fieldWorld Viewsmedicine.medical_specialtyOpen angle glaucomadrug costPopulationSensory OrgansMédecine humaine et pathologiemedical recordDrug Costs03 medical and health sciencesCellular and Molecular Neurosciencehealth care utilizationSeverity of illnessfollow upHumanshumanSex Distribution[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organseducationutilization reviewSettore MED/30 - Malattie Apparato Visivobusiness.industryGlaucomaeconomicssex ratiomedicine.diseasemajor clinical studyeye diseasesOphthalmologymulticenter studygeneral practitionerEmergency medicine030221 ophthalmology & optometryOptometryHuman health and pathologyVisual Fieldsbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyFollow-Up Studies
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Wavelength dependence of the optomotor response in zebrafish (Danio rerio)

2003

Abstract The action spectrum of motion detection in zebrafish (Danio rerio) was measured using the optomotor response in the light adapted state. The function has a single maximum at 550–600 nm, and is similar to the spectral sensitivity function of the L-cone type in the mid and long wavelength range. At shorter wavelengths the values of three of the five fish tested are lower. As in goldfish [Vis. Res. 36 (1996) 4025], the result indicates a dominance of the L-cone type with an inhibitory influence of M- or S-cones. Experiments with a red/green striped cylinder showed that the optomotor response was at minimum whenever the L-cone type was not modulated by the moving pattern. This demonstr…

Maleanimal structuresgenetic structuresColor visionMotion PerceptionDanioColor Vision DefectsMotionOpticsZebrafish (Danio rerio)AnimalsZebrafishZebrafishAction spectrumPhysicsbiologybusiness.industryColor visionMotion detectionbiology.organism_classificationSensory SystemsWavelengthOphthalmologySpectral sensitivityPattern Recognition VisualOptomotor responseFemalesense organsbusinessOptomotor responseColor PerceptionOptometryVision Research
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Probabilistic graphical model identifies clusters of EEG patterns in recordings from neonates

2018

Abstract Objectives In this paper we introduce a novel method for the evaluation of neonatal brain function via multivariate EEG (electroencephalography) signal processing and embedding into a probabilistic graph, the so called Chow-Liu tree. Methods Using 28 EEG recordings of preterm and term neonate infants the complex features of the EEG signals were constructed in the form of a Chow-Liu tree. The trees were embedded into a 3 dimensional Euclidean space. Clustering of specific EEG patterns was done by complete linkage algorithm. Results Our analytic tool was able to build clusters of patients with pathological EEG findings. In particular, we were able to make a visual proof on a 3d multi…

Malebrain monitoringComputer scienceautomated detectionModels Neurologicalmulti-dimensional scalingElectroencephalographyChow-Liu tree050105 experimental psychologyChow–Liu tree03 medical and health sciences0302 clinical medicineNeonatePhysiology (medical)medicineHumans0501 psychology and cognitive sciencesGraphical modelMultidimensional scalingCluster analysismedicine.diagnostic_testbusiness.industry05 social sciencesProbabilistic logicInfant NewbornBrainPattern recognitionTree (graph theory)Brain WavesSensory SystemsComplete linkageNeurologyFemaleNeurology (clinical)Artificial intelligencebusiness030217 neurology & neurosurgeryelectroencephalography
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