Search results for "Separation method"

showing 8 items of 18 documents

Evanescent wave-initiated photopolymerisation as a new way to create monolithic open-tubular capillary columns: use as enzymatic microreactor for on-…

2010

Evanescent wave-initiated photopolymerisation in an optically wave guiding PTFE-coated fused silica capillary using light-emitting diode as a light source, is established here as a way to fabricate monolithic porous layer open-tubular capillary columns with a potential in capillary separation methods; application of the obtained open-tubular columns as enzymatic microreactors for on-line protein digestion is demonstrated.

Evanescent waveUltraviolet RaysProtein digestionCapillary actionBiochemistryMass SpectrometryAnalytical ChemistryBioreactorsLight sourceCapillary ElectrochromatographyElectrochemistryAnimalsEnvironmental ChemistryHorsesPorous layerPolytetrafluoroethyleneSpectroscopyChromatographyMyoglobinChemistryProteinsSilicon DioxidePepsin ALine (electrical engineering)EnzymesChemical engineeringSeparation methodMicroreactorPorosityThe Analyst
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The effect of alertness and attention on the modulation of the beta rhythm to tactile stimulation

2021

Abstract Beta rhythm modulation has been used as a biomarker to reflect the functional state of the sensorimotor cortex in both healthy subjects and patients. Here, the effect of reduced alertness and active attention to the stimulus on beta rhythm modulation was investigated. Beta rhythm modulation to tactile stimulation of the index finger was recorded simultaneously with MEG and EEG in 23 healthy subjects (mean 23, range 19–35 years). The temporal spectral evolution method was used to obtain the peak amplitudes of beta suppression and rebound in three different conditions (neutral, snooze, and attention). Neither snooze nor attention to the stimulus affected significantly the strength of…

MalePhysiologyEvent related synchronization030204 cardiovascular system & hematology0302 clinical medicinevigilanceAttentionEEGkosketusevent-related synchronizationMEGneuropsykologiaEvent related desynchronization1184 Genetics developmental biology physiologyMagnetoencephalographyElectroencephalographyBAND OSCILLATIONSvireysstimulointiFemaleOriginal ArticleSensorimotor CortexPsychologyaivotArousalCORTICAL OSCILLATIONSevent‐related desynchronizationAdultFREQUENCY ACTIVITYMU RHYTHMMental fatigueELECTRICAL-ACTIVITYLibrary sciencesensomotoriikkatuntoaistibeta oscillation03 medical and health sciencesMOVEMENTYoung Adultevent‐related synchronizationSPACE SEPARATION METHODPhysiology (medical)Physical StimulationHumansMENTAL FATIGUEtarkkaavaisuusFunding AgencyPRIMARY MOTOR CORTEXOriginal ArticlesAlertnessaivokuoriTouchCortical oscillationsBeta Rhythm030217 neurology & neurosurgeryevent-related desynchronization
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Supramolecular complexation for environmental control

2012

Supramolecular complexes offer a new and efficient way for the monitoring and removal of many substances emanating from technical processes, fertilization, plant and animal protection, or e.g. chemotherapy. Such pollutants range from toxic or radioactive metal ions and anions to chemical side products, herbicides, pesticides to drugs including steroids, and include degradation products from natural sources. The applications involve usually fast and reversible complex formation, due to prevailing non-covalent interactions. This is of importance for sensing as well as for separation techniques, where the often expensive host compounds can then be reused almost indefinitely. Immobilization of …

Models MolecularPollutantMacrocyclic CompoundsOrganic chemicalsChemistryComplex formationSupramolecular chemistryNew materialsNanotechnologyEquipment DesignGeneral ChemistryMetalsAnimalsHumansSeparation methodEnvironmental PollutantsOrganic ChemicalsEnvironmental Restoration and RemediationEnvironmental MonitoringChemical Society Reviews
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ChemInform Abstract: Supramolecular Complexation for Environmental Control

2012

Supramolecular complexes offer a new and efficient way for the monitoring and removal of many substances emanating from technical processes, fertilization, plant and animal protection, or e.g. chemotherapy. Such pollutants range from toxic or radioactive metal ions and anions to chemical side products, herbicides, pesticides to drugs including steroids, and include degradation products from natural sources. The applications involve usually fast and reversible complex formation, due to prevailing non-covalent interactions. This is of importance for sensing as well as for separation techniques, where the often expensive host compounds can then be reused almost indefinitely. Immobilization of …

PollutantChemistryComplex formationSupramolecular chemistrySeparation methodNew materialsGeneral MedicineBiochemical engineeringChemInform
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Capillary electroendoosmotic chromatography of peptides

2000

This review focuses on the current state of peptide separation by capillary electroendoosmotic chromatography (CEC). When carried out under optimised conditions, peptide separation by CEC methods represents an orthogonal and complementary technique to micro-HPLC (micro-HPLC) and high-performance capillary zone electrophoresis (HPCZE). The origin of the selectivity differences that can be achieved with these three separation techniques (CEC, micro-HPLC and HPCZE), respectively are discussed, and the current limits of performance with CEC methods documented. Peptide separations by CEC methods with n-alkyl bonded silicas or mixed-mode phases are also illustrated. The development of different v…

chemistry.chemical_classificationPeptide fragmentChromatographyChemistryCapillary actionOrganic ChemistryAnalytical chemistryElectrophoresis CapillaryPeptideGeneral MedicineMass spectrometryBiochemistryHigh-performance liquid chromatographyAnalytical ChemistryCapillary electrophoresisElectrochromatographyTerminology as Topiccardiovascular systemSeparation methodAmino AcidsPeptidesChromatography High Pressure LiquidJournal of Chromatography A
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Polymer- and template-related factors influencing the efficiency in molecularly imprinted solid-phase extractions

1999

Abstract This review identifies the factors of importance in the development of molecularly imprinted polymers for use in solid-phase extractions and summarizes the results obtained to date in the area of bioanalysis, pharmaceutical analysis and environmental analysis.

chemistry.chemical_classificationRelated factorsBioanalysisChromatographychemistryEnvironmental analysisPhase (matter)Molecularly imprinted polymerSeparation methodPolymerSolid phase extractionSpectroscopyAnalytical ChemistryTrAC Trends in Analytical Chemistry
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Determining nanomaterials in food

2011

Abstract Nanotechnology has emerged as one of the most innovative technologies and has the potential to improve food quality and safety. However, there are a few studies demonstrating that nanomaterials (NMs) are not inherently benign. This review highlights some current applications of NMs in food, food additives and food-contact materials, and reviews analytical approaches suitable to address food-safety issues related to nanotechnology. We start with a preliminary discussion on the current regulatory situation with respect to nanotechnology in relation to foods. We cover sample preparation, imaging techniques (e.g., electron microscopy, scanning electron microscopy and X-ray microscopy),…

food.ingredientFood securityChemistryFood additivedigestive oral and skin physiologyAnalytical chemistryNanotechnologyConsumer safetyFood AnalysisAnalytical ChemistryCharacterization (materials science)NanomaterialsFood packagingfoodSeparation methodSpectroscopyTrAC Trends in Analytical Chemistry
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SUBFRACTIONS AND SUBPOPULATIONS OF HDL: AN UPDATE

2014

High-density lipoproteins (HDL) are classified as atheroprotective because they are involved in transport of cholesterol to the liver, known as "reverse cholesterol transport (RCT)" exerting antioxidant and anti-inflammatory activities. There is also evidence for cytoprotective, vasodilatory, antithrombotic, and anti-infectious activities for these lipoproteins. HDLs are known by structural, metabolic and biologic heterogeneity. Thus, different methods are able to distinguish several subclasses of HDL. Different separation techniques appear to support different HDL fractions as being atheroprotective or related with lower cardiovascular (CV) risk. However, HDL particles are not always prote…

medicine.medical_specialtyPharmacologyBiologySystemic inflammationBiochemistrychemistry.chemical_compoundRisk FactorsInternal medicineDrug DiscoveryAntithromboticmedicineAnimalsHumansHdl functionalityPharmacologyCholesterolOrganic ChemistryReverse cholesterol transportBiomarker (cell)EndocrinologychemistryCardiovascular DiseasesMolecular MedicineSeparation methodlipids (amino acids peptides and proteins)Hdl subfractionscardiovascular risk electrophoresis high-density lipoprotein nuclear magnetic resonance proteome subclasses subfractions ultracentrifugation.medicine.symptomLipoproteins HDL
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