Search results for "Sequence"

showing 10 items of 4987 documents

X!TandemPipeline: a tool to manage sequence redundancy for protein inference and phosphosite identification

2017

X!TandemPipeline is a software designed to perform protein inference and to manage redundancy in the results of phosphosite identification by database search. It provides the minimal list of proteins or phosphosites that are present in a set of samples using grouping algorithms based on the principle of parsimony. Regarding proteins, a two-level classification is performed, where groups gather proteins sharing at least one peptide and subgroups gather proteins that are not distinguishable according to the identified peptides. Regarding phosphosites, an innovative approach based on the concept of phosphoisland is used to gather overlapping phosphopeptides. The graphical interface of X!Tandem…

0106 biological sciences0301 basic medicinePhosphopeptidesProteomicsphosphopeptideComputer sciencecomputer.internet_protocolcomputer.software_genre01 natural sciencesBiochemistrydatabase search03 medical and health sciencesSearch engineUser-Computer InterfaceRedundancy (information theory)SoftwareTandem Mass Spectrometry[ INFO.INFO-BI ] Computer Science [cs]/Bioinformatics [q-bio.QM]HumansDatabase search engineAmino Acid SequenceDatabases ProteinGraphical user interfacemass spectrometrybusiness.industrysoftwareprotein inferenceProteinsGeneral ChemistrybioinformaticsSearch EngineBenchmarking030104 developmental biologyComputingMethodologies_PATTERNRECOGNITIONProtein inferenceData mining[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]businesscomputerXMLAlgorithms010606 plant biology & botany
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Multilocus sequence typing analysis of Italian Xanthomonas campestris pv. campestris strains suggests the evolution of local endemic populations of t…

2019

Xanthomonas campestris pv. campestris (Xcc) is the causal agent of black rot in Brassicaceae. It is widespread in Italy and severe outbreaks occur under conditions that favour disease development. In this study a multilocus sequence typing approach (MLST) based on the partial sequence of seven loci was applied to a selection of strains representative of the main areas of cultivation and hosts. The aim was to investigate whether the long tradition of brassica crops in Italy has influenced the evolution of different Xcc populations. All loci were polymorphic; 14 allelic profiles were identified of which 13 were unique to Italian strains. Based on the seven loci, the most common genotype withi…

0106 biological sciences0301 basic medicinePlant ScienceBiologyHorticulture01 natural sciencesXanthomonas campestris pv. campestris03 medical and health sciencesRace (biology)PhylogeneticsGenotypeGeneticsrace designationXanthomonas campestris pv. campestrisEndemismPathogenGeneticspopulation diversityblack rot of Brassicaceae MLST population diversity race designation Xanthomonas campestris pv. campestris Agronomy and Crop Science Genetics Plant Science HorticultureBlack rot of Brassicaeae Xanthomonas campestris pv. campestris MLST race designation population diversity.Outbreakbiology.organism_classificationBlack rot of Brassicaeae030104 developmental biologyMultilocus sequence typingblack rot of BrassicaceaeAgronomy and Crop ScienceXanthomonas campestris pv. campestri010606 plant biology & botanyMLST
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The evolution of dwarf shrubs in alpine environments: a case study ofAlchemillain Africa

2015

BACKGROUND AND AIMS Alpine and arctic environments worldwide, including high mountains, are dominated by short-stature woody plants (dwarf shrubs). This conspicuous life form asserts considerable influence on local environmental conditions above the treeline, creating its own microhabitat. This study reconstructs the evolution of dwarf shrubs in Alchemilla in the African tropical alpine environment, where they represent one of the largest clades and are among the most common and abundant plants. METHODS Different phylogenetic inference methods were used with plastid and nuclear DNA sequence markers, molecular dating (BEAST and RelTime), analyses of diversification rate shifts (MEDUSA and BA…

0106 biological sciences0301 basic medicinePleistoceneved/biology.organism_classification_rank.speciesPlant Science010603 evolutionary biology01 natural sciencesShrub03 medical and health sciencesRosoideaeAlchemillaEcosystemPhylogenyGeographybiologyEcologyved/biologyTemperatureGenetic VariationSequence Analysis DNAOriginal Articlesbiology.organism_classificationBiological Evolution030104 developmental biologyArcticAfricaBiological dispersalAdaptationAlchemillaWoody plantAnnals of Botany
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Simultaneous speciation in the European high mountain flowering plant genus Facchinia (Minuartia s.l., Caryophyllaceae) revealed by genotyping-by-seq…

2017

Understanding the relative importance of different mechanisms of speciation in a given lineage requires fully resolved interspecific relationships. Using Facchinia, a genus of seven species centred in the European Alps, we explore whether the polytomy found by Sanger sequencing analyses of standard nuclear (ITS) and plastid markers (trnQ-rps16) is a hard or soft polytomy by substantially increasing the amount of DNA sequence data, generated by genotyping-by-sequencing. In comparison to 142 phylogenetically informative sites in the Sanger sequences the GBS sequences yielded 3363 phylogenetically informative sites after exclusion of apparently oversaturated SNPs. Maximum parsimony, maximum li…

0106 biological sciences0301 basic medicinePolytomyDNA PlantGenotypeGenetic SpeciationLineage (evolution)CaryophyllaceaeBiology010603 evolutionary biology01 natural sciencesCoalescent theoryEvolution Molecular03 medical and health sciencessymbols.namesakePhylogeneticsGeneticsPlastidsMolecular BiologyPhylogenyEcology Evolution Behavior and SystematicsGeneticsSanger sequencingPhylogenetic treeSequence Analysis DNAMaximum parsimony030104 developmental biologyMolecular phylogeneticssymbolsHybridization GeneticMolecular Phylogenetics and Evolution
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Blattella germanica displays a large arsenal of antimicrobial peptide genes

2020

Defence systems against microbial pathogens are present in most living beings. The German cockroach Blattella germanica requires these systems to adapt to unhealthy environments with abundance of pathogenic microbes, in addition to potentially control its symbiotic systems. To handle this situation, four antimicrobial gene families (defensins, termicins, drosomycins and attacins) were expanded in its genome. Remarkably, a new gene family (blattellicins) emerged recently after duplication and fast evolution of an attacin gene, which is now encoding larger proteins with the presence of a long stretch of glutamines and glutamic acids. Phylogenetic reconstruction, within Blattellinae, suggests …

0106 biological sciences0301 basic medicinePore Forming Cytotoxic ProteinsGenome InsectEvolutionary biology010603 evolutionary biology01 natural sciencesGenomeArticle03 medical and health sciencesProtein DomainsPhylogeneticsGene duplicationGene expressionGene familyAnimalsAmino Acid SequenceSymbiosisGenePhylogenyRegulation of gene expressionGeneticsGerman cockroachMultidisciplinarybiologyAntimicrobial responsesBlattellidaebiology.organism_classificationGenome evolution030104 developmental biologyGene Expression RegulationEntomology
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Inter- and intra-specific genomic divergence in Drosophila montana shows evidence for cold adaptation

2018

This work was supported by the Academy of Finland to AH (projects 132619 and 267244) and to MK (projects 268214 and 272927) and NERC (UK) funding to MGR (grants NE/E015255/1 and NE/J020818/1) and PhD studentship to DJP (NE/I528634/1). The genomes of species that are ecological specialists will likely contain signatures of genomic adaptation to their niche. However, distinguishing genes related to ecological specialism from other sources of selection and more random changes is a challenge. Here we describe the genome of Drosophila montana, which is the most extremely cold-adapted Drosophila species. We use branch tests to identify genes showing accelerated divergence in contrasts between col…

0106 biological sciences0301 basic medicineQH301 BiologyAcclimatizationGenome Insectcomparative genomics01 natural sciencesGenomekylmänkestävyysDrosophilia montanaPhylogenysopeutuminen0303 health scienceseducation.field_of_studybiologygenomiikkaCold TemperatureDrosophilaSynonymous substitutionResearch ArticlemahlakärpäsetNichePopulationGenomics010603 evolutionary biologyIntraspecific competitionQH30103 medical and health sciencesecological adaptationPhylogeneticsDrosophila montanaGeneticsAnimalsDrosophila (subgenus)educationGeneEcology Evolution Behavior and Systematics030304 developmental biologyComparative genomicsta1184DASMolecular Sequence Annotationcold tolerancebiology.organism_classificationDiapauseAcclimatization; Animals; Cold Temperature; Diapause; Drosophila/classification; Drosophila/genetics; Drosophila/physiology; Genome Insect; Molecular Sequence Annotation; Phylogeny030104 developmental biologyEvolutionary biologyta1181Adaptation
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Topological congruence between phylogenies of Anacanthorus spp. (Monogenea: Dactylogyridae) and their Characiformes (Actinopterygii) hosts: A case of…

2017

Cophylogenetic studies aim at testing specific hypotheses to understand the nature of coevolving associations between sets of organisms, such as host and parasites. Monogeneans and their hosts provide and interesting platform for these studies due to their high host specificity. In this context, the objective of the present study was to establish whether the relationship between Anacanthorus spp. with their hosts from the upper Paraná River and its tributaries can be explained by means of cospeciation processes. Nine fish species and 14 monogenean species, most of them host specific, were studied. Partial DNA sequences of the genes RAG1, 16S and COI of the fish hosts and of the genes ITS2, …

0106 biological sciences0301 basic medicineSpeciationlcsh:MedicineAnimal PhylogeneticsCharaciformes01 natural sciencesDatabase and Informatics MethodsRNA Ribosomal 16Slcsh:ScienceDNA extractionPhylogenyData ManagementMultidisciplinaryGeographyPhylogenetic treebiologyEukaryotaPhylogenetic AnalysisPhylogeneticsFreshwater FishPhylogeographyBiogeographyVertebratesCharaciformesSequence AnalysisMonogeneaResearch ArticleComputer and Information SciencesEvolutionary ProcessesBioinformaticsContext (language use)Topology010603 evolutionary biologyHost-Parasite InteractionsElectron Transport Complex IV03 medical and health sciencesExtraction techniquesPhylogeneticsGeneticsAnimalsEvolutionary SystematicsParasite EvolutionTaxonomyHomeodomain ProteinsEvolutionary BiologyPopulation BiologyHost (biology)lcsh:REcology and Environmental SciencesOrganismsBiology and Life SciencesDNASequence Analysis DNAbiology.organism_classificationDactylogyridaeResearch and analysis methodsPhylogeographyFish030104 developmental biologyPlatyhelminthsEarth Scienceslcsh:QParasitologyZoologySequence AlignmentPopulation GeneticsPLOS ONE
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Is the ballan wrasse (Labrus bergylta) two species? Genetic analysis reveals within-species divergence associated with plain and spotted morphotype f…

2016

Abstract The ballan wrasse (Labrus bergylta) is a marine fish belonging to the family Labridae characterized by 2 main morphotypes that occur in sympatry: spotty and plain. Previous studies have revealed differences in their life‐history traits, such as growth and maturation; however, the genetic relationship between forms is presently unknown. Using 20 recently developed microsatellite markers, we conducted a genetic analysis of 41 and 48 spotty and plain ballan wrasse collected in Galicia (northwest Spain). The 2 morphotypes displayed highly significant genetic differences to each other (F ST = 0.018, P < 0.0001). A similar degree of genetic differentiation (F ST = 0.025, P < 0.0001) was …

0106 biological sciences0301 basic medicineSympatryballan wrasseShort CommunicationZoologyGenetic relationshipLabrus bergyltaDNA Mitochondrial010603 evolutionary biology01 natural sciencesGenetic analysismicrosatellitesPerciformes03 medical and health sciencesAnimalsbiologyGenetic heterogeneitycolor morphotypesSequence Analysis DNALabrus bergyltabiology.organism_classificationPerciformesSympatry030104 developmental biologyspeciationSpainWrasseMicrosatelliteAnimal Science and ZoologyMicrosatellite RepeatsIntegrative Zoology
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Characterization of a β-glucosidase isolated from an alpeorujo strain of Candida adriatica

2017

ABSTRACTA β-glucosidase-producing strain, Candida adriatica CECT13142, was isolated from olive oil wastes (alpeorujo) and identified by PCR/restriction fragment length polymorphism of the rDNA internal transcribed spacer and sequence analysis of the D1/D2 region of the 26S rRNA gene techniques. The enzyme was purified by sequential chromatography on DEAE-cellulose and Sephadex G-100. The relative molecular mass of the enzyme was estimated to be 50 kDa by SDS-PAGE. The hydrolytic activity of the β-glucosidase had an optimum pH of 8.2 and an optimum temperature of 40°C. The enzyme displayed high substrate specificity and high catalytic efficiency (Km 0.85 mM, Vmax 12.5 U/g of cells) for p-nit…

0106 biological sciences0301 basic medicinechemistry.chemical_classificationMolecular massStrain (chemistry)Sequence analysisRibosomal RNABiology01 natural sciencesApplied Microbiology and Biotechnology03 medical and health sciences030104 developmental biologyEnzymeBiochemistrychemistrySephadex010608 biotechnologyInternal transcribed spacerRestriction fragment length polymorphismFood ScienceBiotechnologyFood Biotechnology
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Genetic diversity of Rhizoctonia solani associated with potato tubers in France.

2011

Publication Inra prise en compte dans l'analyse bibliométrique des publications scientifiques mondiales sur les Fruits, les Légumes et la Pomme de terre. Période 2000-2012. http://prodinra.inra.fr/record/256699; International audience; The soilborne fungus Rhizoctonia solani is a pathogen of many plants and causes severe damage in crops around the world. Strains of R. solani from the anastomosis group (AG) 3 attack potatoes, leading to great yield losses and to the downgrading of production. The study of the genetic diversity of the strains of R. solani in France allows the structure of the populations to be determined and adapted control strategies against this pathogen to be established. …

0106 biological sciences0301 basic medicineinternal transcribed spacer polymorphic sitePhysiologyMolecular Sequence Dataanastomosis groupBiology010603 evolutionary biology01 natural sciencesamplified fragment length polymorphismRhizoctoniaRhizoctonia solani03 medical and health sciencesGenetic variationBotanyDNA Ribosomal SpacerGeneticsInternal transcribed spacerAmplified Fragment Length Polymorphism AnalysisMolecular BiologyEcology Evolution Behavior and Systematics[SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/MycologyPhylogenySolanum tuberosum2. Zero hungerGeneticsGenetic diversityPhylogenetic treeBase SequenceRhizoctonia solanifood and beveragesGenetic VariationCell BiologyGeneral Medicine030108 mycology & parasitologyRibosomal RNAbiology.organism_classificationelongation factorDNA profilingpotatoAmplified fragment length polymorphismFranceanastamoseMycologia
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