Search results for "Severe acute respiratory syndrome"

showing 10 items of 566 documents

A Trial of Lopinavir–Ritonavir in Covid-19

2020

Adult2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralLopinavir/ritonavirPharmacologyLopinavirBetacoronavirusmedicineHumansPandemicsRitonavirBetacoronaviruPandemicCoronavirus InfectionSARS-CoV-2business.industryCOVID-19LopinavirGeneral MedicineCOVID-19 Drug TreatmentRitonavirCoronavirus InfectionsbusinessCoronavirus InfectionsHumanmedicine.drugNew England Journal of Medicine
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Impact of coronavirus disease 2019 (COVID-19) outbreak on radiology research: An Italian survey

2021

Abstract Purpose To understand how COVID-19 pandemic has changed radiology research in Italy. Methods A questionnaire (n = 19 questions) was sent to all members of the Italian Society of Radiology two months after the first Italian national lockdown was lifted. Results A total of 327 Italian radiologists took part in the survey (mean age: 49 ± 12 years). After national lockdown, the working-flow came back to normal in the vast majority of cases (285/327, 87.2%). Participants reported that a total of 462 radiological trials were recruiting patients at their institutions prior to COVID-19 outbreak, of which 332 (71.9%) were stopped during the emergency. On the other hand, 252 radiological tri…

Adult2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ArticleTrialSurveys and QuestionnairesPandemicSurveys and QuestionnaireHumansMedicineRadiology Nuclear Medicine and imagingPandemicsPractice Policy & EducationPandemicSARS-CoV-2business.industryResearchOutbreakMean ageMiddle AgedItalyRadiology Nuclear Medicine and imagingRadiologistRadiological weaponCommunicable Disease ControlRadiologyRadiologyCovid-19businessHumanClinical Imaging
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Thinking of future as an older individual increases perceived risks for age‐related diseases but not for COVID‐19

2022

Actively thinking of one's future as an older individual could increase perceived risk and risk aversion. This could be particularly relevant for COVID-19, if we consider the common representation of the risk of being infected by COVID-19 as associated with being older. Increased perceived risk could bear consequences on the adoption of preventive behaviours. Thus, we investigated whether increasing the salience of individuals' future as an older adult would impact on their perceived risk for COVID-19 and medical conditions varying for age-relatedness. One hundred and forty-four Italian adults (Mage = 27.72, range: 18–56) were randomly assigned to either a future as older adult thinking or …

AdultAging2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)050109 social psychology050105 experimental psychologyDevelopmental psychologyArts and Humanities (miscellaneous)COVID‐19risk perceptionAge relatedAge priming; Age-related diseases; COVID-19; Future-oriented thinking; Risk perceptionHumansAge‐related diseases0501 psychology and cognitive sciencesGeneral PsychologyAgedage-related diseaseSalience (language)SARS-CoV-2Risk aversion05 social sciencesCOVID-19General MedicineFuture‐oriented thinkingRisk perceptionfuture-oriented thinkingCross-Sectional StudiesItalyRegular Empirical ArticleRegular Empirical ArticlesPsychologyAge-related diseasesage primingInternational Journal of Psychology
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The Quest for Predictors of Shunt-Dependent Chronic Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage: Toward a Tailored Approach for Permanent …

2021

AdultAneurysmal subarachnoid hemorrhage Cerebrospinal fluid (CSF) output External ventricular drainage Hydrocephalus Adult Cerebrospinal Fluid Shunts Chronic Disease Aged Humans Hydrocephalus Ventriculoperitoneal Shunt Predictive Value of Tests Middle Aged Subarachnoid Hemorrhage Risk Assessment Prognosis Treatment OutcomeCerebrospinal fluid (CSF) output2019-20 coronavirus outbreakmedicine.medical_specialtySubarachnoid hemorrhageCoronavirus disease 2019 (COVID-19)Aneurysmal subarachnoid hemorrhageSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Risk AssessmentVentriculoperitoneal ShuntPredictive Value of TestsmedicineHumansAgedbusiness.industryExternal ventricular drainageMiddle AgedSubarachnoid Hemorrhagemedicine.diseasePrognosisChronic hydrocephalusCerebrospinal Fluid ShuntsHydrocephalusShunt (medical)SurgeryTreatment OutcomeChronic DiseaseSurgeryNeurology (clinical)businessHydrocephalus
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Addressing the impact of SARS-CoV-2 infection in persons with congenital bleeding disorders: The Italian MECCOVID-19 study

2021

congenital bleeding disorders

AdultInheritedMalePediatricsmedicine.medical_specialty2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)congenital bleeding disorderscongenital bleeding disorderSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)haemophiliaHemorrhageHaemophiliaLetter to the EditorsSARS‐CoV‐2Young AdultBlood Coagulation Disorders InheritedCOVID‐19congenital bleeding disorders; COVID-19; epidemiology; haemophilia; observational study; SARS-CoV-2; Adult; Aged; Blood Coagulation Disorders Inherited; COVID-19; Child Preschool; Disease Management; Female; Hemorrhage; Humans; Italy; Male; Middle Aged; SARS-CoV-2; Young AdultEpidemiologymedicineHumansYoung adultDisease management (health)ChildPreschoolLetter to the EditorGenetics (clinical)Agedbusiness.industrySARS-CoV-2COVID-19Disease ManagementHematologyGeneral MedicineBlood Coagulation DisordersMiddle Agedmedicine.diseaseItalySARS-CoV-2.Child PreschoolObservational studyepidemiologyobservational studyFemalebusiness
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Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study

2022

Breast milk is a vehicle to transfer protective antibodies from the lactating mother to the neonate. After SARS-CoV-2 infection, virus-specific IgA and IgG have been identified in breast milk, however, there are limited data on the impact of different COVID-19 vaccine types in lactating women. This study is aimed to evaluate the time course of induction of SARS-CoV-2-specific IgA and IgG in breast milk after vaccination.

AdultLongitudinal studyBreast milkCOVID-19 VaccinesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BreastfeedingimmunoglobulinsImmunoglobulinsBreast milkAntibodies ViralVacunesAntibodiesVirusPersistence (computer science)ChAdOx1 nCoV-19GeneticsHumansLactationMedicineantibodiesLongitudinal Studiesskin and connective tissue diseasesMolecular BiologyBNT162 VaccineGenetics (clinical)Milk Humanbiologybusiness.industrySARS-CoV-2VaccinationInfant Newbornfood and beveragesInfantCOVID-19vaccinesImmunoglobulin AVaccinationLlet maternaImmunoglobulin GImmunologybiology.proteinMolecular Medicinebreast milkFemaleAntibodybusiness
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Epidemiological, clinical and genomic snapshot of the first 100 B.1.1.7 SARS-CoV-2 cases in Madrid

2021

A new SARS-CoV-2 variant, B.1.1.7, emerged in September in the UK, and is responsible for 76.6% of COVID-19 cases.1 This variant has also been reported in another 45 countries, 17 of them European.2,3 B.1.1.7 is considered to have higher transmissibility.4 It carries an unusually high number of specific mutations/deletions, 18, mostly non-synonymous and eight concentrate in the S gene,5 including several which might have relevant functional roles. The 69/70 deletion may be associated to immune response evasion6 and the N501Y substitution increases the affinity to the ACE2 receptor.7 These findings have raised the alarm of having to face a new variant with the potential to accelerate the spr…

AdultMale2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)AdolescentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)030231 tropical medicine03 medical and health sciencesYoung Adult0302 clinical medicineResearch LetterMedicineHumans030212 general & internal medicineUKChildB.1.1.7travelAgedAged 80 and overTravelbusiness.industrySARS-CoV-2InfantCOVID-19General MedicineGenomicsMiddle AgedSpainChild PreschoolFemalebusinessHumanitiesAcademicSubjects/MED00295
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Type I interferons as the potential mechanism linking mRNA COVID-19 vaccines to Bell's palsy

2021

Therapies - Sous presse. Epreuves corrigees par l'auteur. Disponible en ligne depuis le mardi 13 avril 2021

AdultMale2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)COVID-19 vaccines030226 pharmacology & pharmacyArticle03 medical and health sciencesPharmacovigilance0302 clinical medicineBell's palsyPhase 3 clinical trialsBell PalsymedicineType I interferonsHumansBell's palsyPharmacology (medical)Potential mechanismComputingMilieux_MISCELLANEOUSAgedCOVID-19 coronavirus disease 2019Vaccines SyntheticMessenger RNASARS-CoV-2business.industryCOVID-19Bell’s palsyMiddle Agedmedicine.diseaseVirologymRNA messenger RNA3. Good healthInterferon Type IFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusiness
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Incidence of severe COVID-19 outcomes in psoriatic patients treated with systemic therapies during the pandemic: A Biobadaderm cohort analysis

2021

AdultMale2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)prospective cohortMEDLINEDermatologyregistryimmunosuppressive agentsSeverity of Illness IndexCOVID-19 (Malaltia)ArticleCohort StudiesInternal medicinePandemicPsoriasisHumansMedicinebiologic therapyRegistriesAgedbusiness.industryIncidenceIncidence (epidemiology)COVID-19COVID-19 Psoriasis biologic therapy immunosuppressive agents pharmacovigilance prospective cohort registryMiddle AgedSpainpharmacovigilanceFemalebusinessPsoriasi -- TractamentCohort studyJournal of the American Academy of Dermatology
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Neutralizing antibodies against SARS-CoV-2 variants of concern elicited by the comirnaty COVID-19 vaccine in nursing home residents.

2022

Immunosenescence may impact the functionality and breadth of vaccine-elicited humoral immune responses. The ability of sera to neutralize the SARS-CoV-2 spike protein (S) from Beta, Gamma, Delta, and Epsilon variants of concern (VOCs) relative to the ancestral Wuhan-Hu-1 strain was compared in Comirnaty COVID-19-vaccinated elderly nursing home residents, either SARS-CoV-2 naïve (n = 22) or experienced (n = 8), or SARS-CoV-2 naïve younger individuals (n = 18) and non-vaccinated individuals who recovered from severe COVID-19 (n = 19). In all groups, except that including SARS-CoV-2-experienced nursing home residents, some participants lacked NtAb against one or more VOCs, mainly the Beta vari…

AdultMaleCOVID-19 VaccinesCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Antibodies ViralImmune systemProtein DomainsNeutralization TestsMedicineHumansBeta (finance)AgedRetrospective StudiesAged 80 and overMultidisciplinarybiologybusiness.industrySARS-CoV-2COVID-19ImmunosenescenceMiddle AgedAntibodies NeutralizingFold changeImmunity HumoralNursing HomesTiterImmunologySpike Glycoprotein Coronavirusbiology.proteinFemaleAntibodybusinessScientific reports
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