6533b7d7fe1ef96bd1267ab9

RESEARCH PRODUCT

Anti-SARS-CoV-2 IgA and IgG in human milk after vaccination is dependent on vaccine type and previous SARS-CoV-2 exposure: a longitudinal study

Maria Carmen ColladoCarles LerinFrancisco J. Pérez-canoChristine BäuerlAnna Parra-llorcaCecilia Martínez-costaDesirée Mena-tudelaMarta Selma-royoLaia Aguilar-camprubí

subject

AdultLongitudinal studyBreast milkCOVID-19 VaccinesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BreastfeedingimmunoglobulinsImmunoglobulinsBreast milkAntibodies ViralVacunesAntibodiesVirusPersistence (computer science)ChAdOx1 nCoV-19GeneticsHumansLactationMedicineantibodiesLongitudinal Studiesskin and connective tissue diseasesMolecular BiologyBNT162 VaccineGenetics (clinical)Milk Humanbiologybusiness.industrySARS-CoV-2VaccinationInfant Newbornfood and beveragesInfantCOVID-19vaccinesImmunoglobulin AVaccinationLlet maternaImmunoglobulin GImmunologybiology.proteinMolecular Medicinebreast milkFemaleAntibodybusiness

description

Breast milk is a vehicle to transfer protective antibodies from the lactating mother to the neonate. After SARS-CoV-2 infection, virus-specific IgA and IgG have been identified in breast milk, however, there are limited data on the impact of different COVID-19 vaccine types in lactating women. This study is aimed to evaluate the time course of induction of SARS-CoV-2-specific IgA and IgG in breast milk after vaccination.

10.1186/s13073-022-01043-9