Search results for "Shock"
showing 10 items of 1248 documents
Decreased temperature increases the expression of a disordered bacterial late embryogenesis abundant (LEA) protein that enhances natural transformati…
2021
Late embryogenesis abundant (LEA) proteins are important players in the management of responses to stressful conditions, such as drought, high salinity, and changes in temperature. Many LEA proteins do not have defined three-dimensional structures, so they are intrinsically disordered proteins (IDPs) and are often highly hydrophilic. Although LEA-like sequences have been identified in bacterial genomes, the functions of bacterial LEA proteins have been studied only recently. Sequence analysis of outer membrane interleukin receptor I (BilRI) from the oral pathogen Aggregatibacter actinomycetemcomitans indicated that it shared sequence similarity with group 3/3b/4 LEA proteins. Comprehensive …
Identifying conserved genes involved in crop tolerance to cold stress
2022
Low temperature is a limiting factor for crop productivity in tropical and subtropical climates. Cold stress response in plants involves perceiving and relaying the signal through a transcriptional cascade composed of different transduction components, resulting in altered gene activity. We performed a meta-analysis of four previously published datasets of cold-tolerant and cold-sensitive crops to better understand the gene regulatory networks and identify key genes involved in cold stress tolerance conserved across phylogenetically distant species. Re-analysing the raw data with the same bioinformatics pipeline, we identified common cold tolerance-related genes. We found 236 and 242 common…
Polarization and Spectacle in the Spanish Political Talk Show ‘La Sexta Noche’ During the 2019 European Elections
2021
This article analyses how in the main political talk show on television in Spain, La Sexta Noche, the main themes of the European agenda were silenced or conditioned by the themes of the national, regional and local agenda during the last European elec-tions. The media debate was oriented towards an analysis of the results of national elections and the campaign for regional and local elections that al-lowed for a greater spectacle, thanks to the shock effect of such polarized ideol-ogies and the trivialization of national politics. This research has studied all the shows of the programme broad-cast as of the national elections on 28th April 2019 up until the European elections held on 26th …
Complex singularities in KdV solutions
2016
In the small dispersion regime, the KdV solution exhibits rapid oscillations in its spatio-temporal dependence. We show that these oscillations are caused by the presence of complex singularities that approach the real axis. We give a numerical estimate of the asymptotic dynamics of the poles.
A numerical treatment of wet/dry zones in well-balanced hybrid schemes for shallow water flow
2012
The flux-limiting technology that leads to hybrid, high resolution shock capturing schemes for homogeneous conservation laws has been successfully adapted to the non-homogeneous case by the second and third authors. In dealing with balance laws, a key issue is that of well-balancing, which can be achieved in a rather systematic way by considering the 'homogeneous form' of the balance law.The application of these techniques to the shallow water system requires also an appropriate numerical treatment for the wetting/drying interfaces that appear initially or as a result of the flow evolution. In this paper we propose a numerical treatment for wet/dry interfaces that is specifically designed f…
Probing the role of water in protein conformation and function
2004
Life began in a bath of water and has never escaped it. Cellular function has forced the evolution of many mechanisms ensuring that cellular water concentration has never changed significantly. To free oneself of any conceptual distinction among all small molecules, solutes and solvents, means that experiments to probe water's specific role in molecular function can be designed like any classical chemical reaction. Such an ‘osmotic stress’ strategy will be described in general and for an enzyme, hexokinase. Water behaves like a reactant that competes with glucose in binding to hexokinase, and modulates its conformational change and activity. This ‘osmotic stress’ strategy, now applied to ma…
Decipher the mechanisms of protein conformational changes induced by nucleotide binding through free-energy landscape analysis: ATP binding to Hsp70.
2013
ATP regulates the function of many proteins in the cell by transducing its binding and hydrolysis energies into protein conformational changes by mechanisms which are challenging to identify at the atomic scale. Based on molecular dynamics (MD) simulations, a method is proposed to analyze the structural changes induced by ATP binding to a protein by computing the effective free-energy landscape (FEL) of a subset of its coordinates along its amino-acid sequence. The method is applied to characterize the mechanism by which the binding of ATP to the nucleotide-binding domain (NBD) of Hsp70 propagates a signal to its substrate-binding domain (SBD). Unbiased MD simulations were performed for Hsp…
Riemann solvers in relativistic astrophysics
1999
AbstractOur contribution reviews High Resolution Shock Capturing methods (HRSC) in the field of relativistic hydrodynamics with special emphasis on Riemann solvers. HRSC techniques achieve highly accurate numerical approximations (formally second order or better) in smooth regions of the flow, and capture the motion of unresolved steep gradients without creating spurious oscillations. One objective of our contribution is to show how these techniques have been extended to relativistic hydrodynamics, making it possible to explore some challenging astrophysical scenarios. We will review recent literature concerning the main properties of different special relativistic Riemann solvers, and disc…
A Polynomial Approach to the Piecewise Hyperbolic Method
2003
In this paper, a local (third-order accurate) shock capturing method for hyperbolic conservation laws is presented. The method has been made with the same idea as the PHM method, but with a simpler reconstruction. A comparison with the classic high order methods is discussed.
Search, Nash bargaining and rule-of-thumb consumers
2011
Abstract This paper analyses the effects of introducing two typical Keynesian features, namely rule-of-thumb (RoT) consumers and consumption habits, into a standard labour market search model. RoT consumers use the margin that hours and wage negotiation provides them to improve their lifetime utility, by narrowing the gap in utility with respect to Ricardian consumers. This margin for intertemporal optimisation has not been studied yet, because this class of restricted agents has been mainly used in models with no equilibrium unemployment. Our approach allows for a deeper study of the effects of shocks on vacancies, unemployment, hours, wages and how they interact. As habits increase, RoT c…