Search results for "Sign"
showing 10 items of 14733 documents
Co-développement d'un modèle d'aide à la décision pour la gestion intégrée de la flore adventice. Méta-modélisation et analyse de sensibilité d'un mo…
2018
The main threat to agricultural crops are weeds with herbicides being the primary cropping management practice. Due to the negative impact of herbicides on health and environment, their use must be reduced. To replace herbicides, numerous cropping practices need to be implemented. This makes weed management more complicated and, together with necessity of scheduling operations at long-term and the multiplicity of cropping system impacts, explains why models are so useful for designing innovative cropping systems. The aim of this thesis was to develop a Decision Support System (DSS) intended for crop advisors to help design cropping systems that are less dependent on herbicides. Our approach…
Appel nullité. Ordonnance du président du Tribunal de commerce refusant de procéder à la désignation d'un arbitre, Excès de pouvoir, Délai pour agir,…
1998
International audience; (Cass. 2e civ., Bull. civ. II, n° 20, p. 13 ; Rev. arb. 1998. 113, note A. Hory, Consorts Bailly c/ Sté Ets H. Binetruy)
Design, synthesis and biological evaluation of new anticancer drugs: FGFR inhibitors
2021
Fibroblast growth factor receptors (FGFRs) constitute a family of tyrosine kinases receptors (RTKs) that exert pivotal physiological functions in human embryonic and adult tissues. Hyperactivated FGFR signaling drives tumorigenesis in multiple cancer types, including lung and brain cancers. Great effort has been laid on the development of new compounds that specifically target the FGFR axis. However, cancer cell- based and microenvironmental resistance mechanisms against FGFR inhibitors often arise and are currently poorly understood. Furthermore, FGFR-targeted therapy often presents different side effects, e due to the broad biological spectrum of the FGFR signaling axis as well as to its …
Effect of two distinct implant macro-designs on the osseointegration of bicortically installed implants in two topographic sites. A histomorphometric…
2019
Antecedentes científicos y objetivos de estudio: El uso de implantes dentales como alternativa para la rehabilitación oral ha demostrado su eficacia y mostrando altas tasas de supervivencia. Un aspecto clave de la osteointegración del implante dental está relacionado con la obtención de una estabilidad primaria adecuada, asegurada por el enclavamiento mecánico entre el tejido óseo y la interfaz del implante, la cual depende en parte de la geometría del implante, la rugosidad de la superficie y la técnica quirúrgica para la preparación del lecho implantario. Varios factores están involucrados en la interacción entre la superficie del implante y el hueso nativo circundante durante la osteoint…
A Viscoelastic Model for the Long-Term Deflection of Segmental Prestressed Box Girders
2017
Most of segmental prestressed concrete box girders exhibit excessive multidecade deflections unforeseeable by past and current design codes. To investigate such a behavior, mainly caused by creep and shrinkage phenomena, an effective finite element (FE) formulation is presented in this article. This formulation is developed by invoking the stationarity of an energetic principle for linear viscoelastic problems and relies on the Bazant creep constitutive law. A case study representative of segmental prestressed concrete box girders susceptible to creep is also analyzed in the article, that is, the Colle Isarco viaduct. Its FE model, based on the aforementioned energetic formulation, was succ…
Identification and Experimental Validation of an Induction Motor Thermal Model for Improved Drivetrain Design
2017
The ability of an electric powertrain to perform according to mechanical specifications is equally important as assessing its thermal protection limits, which are affected by its electrical and thermal properties. Although rated parameters (such as power, torque, etc.) are easily accessible in catalogs of equipment producers, more specific properties like mass/length of copper winding, heat dissipation factor, etc., are not available to customers. Therefore, an effective selection of drivetrain components is limited due to the lack of sufficient data and the need to consult critical design decisions with suppliers. To overcome this limitation, we propose a method to estimate the temperature…
Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor
2002
Ciliary neurotrophic factor (CNTF) displays neurotrophic activities on motor neurons and neural cell populations both in vivo and in vitro. On target cells lacking intrinsic expression of specific receptor alpha subunits cytokines of the IL-6 family only act in the presence of their specific agonistic soluble receptors. Here, we report the construction and expression of a CNTF/soluble CNTF-receptor (sCNTF-R) fusion protein (Hyper-CNTF) with enhanced biological activity on cells expressing gp130 and leukemia inhibitory factor receptor (LIF-R), but not membrane-bound CNTF-R. At the cDNA level, the C-terminus of the extracellular domain of human CNTF-R (amino acids 1-346) was linked via a sing…
Hyperfine interaction in the Autler-Townes effect: The formation of bright, dark, and chameleon states
2017
This paper is devoted to clarifying the implications of hyperfine (HF) interaction in the formation of adiabatic (i.e., ``laser-dressed'') states and their expression in the Autler-Townes (AT) spectra. We first use the Morris-Shore model [J. R. Morris and B. W. Shore, Phys. Rev. A 27, 906 (1983)] to illustrate how bright and dark states are formed in a simple reference system where closely spaced energy levels are coupled to a single state with a strong laser field with the respective Rabi frequency ${\mathrm{\ensuremath{\Omega}}}_{S}$. We then expand the simulations to realistic hyperfine level systems in Na atoms for a more general case when non-negligible HF interaction can be treated as…
Tuning four-wave mixing through temperature in ethanol-filled photonic crystal fiber
2016
In this paper, continuous tuning of four-wave mixing bands in an ethanol-filled photonic crystal fiber is investigated. A wide tuning range of the parametric bands, from 745 nm to 920 nm (signal) and from 1260 nm to 1710 nm (idler), is achieved through the thermo-optic effect. This corresponds to a frequency tuning range higher than 2000 cm−1; such wide range can be particularly useful in applications that require broadband wavelength conversion, e.g., CARS microscopy. Numerical calculations are in good agreement with experimental measurements.
Ridge-line optimal detector
2000
Image processing techniques have seen many developments in recent years. Starting from the pioneering work of Canny, Deriche developed a second order recursive filter capable of detecting stepped contours. However, there are other contour shapes that those filters struggle to detect. We describe a new optimal filter sensu Canny for detecting ridge-line contours. This is a third order recursive and even filter. It is dependent on three parameters by which detection accuracy is adjusted. The results obtained by applying this filter to (possibly noise- affected) images are compared with those in the work by Ziou. © 2000 Society of Photo-Optical Instrumentation Engineers. (S0091-3286(00)00706-6)