Search results for "Sign"

Approximation of measurements results of „EMERGENCY” signal reception probability

2017

W artykule przedstawiono wyniki aproksymacji przykładowych danych pomiaru prawdopodobieństwa odbioru sygnału NIEBEZPIECZEŃSTWO. Prawdopodobieństwo to rozpatruje się jako funkcję odległości pomiędzy statkiem powietrznym a systemem naziemnym w ustalonych warunkach pomiaru. Aproksymację danych pomiarowych zrealizowano korzystając z własności funkcji logistycznej. Prawdopodobieństwo jako funkcja odległości pozwala na określenie zasięgu sygnału NIEBEZPIECZEŃSTWO dla zadanego poziomu ufności.

Optical quality of hyperopic and myopic phakic intraocular lenses

2013

Aims: To assess and compare the optical quality of the myopic and hyperopic implantable collamer lens (ICL) from its wavefront aberrations for different powers and pupil diameters. Settings and Design: Prospective study. Material and Methods: The wavefront aberrations of two myopic (−3 and −6 diopters (D)) and two hyperopic V4b ICLs (+3 and +6D) were measured in vitro . To assess and compare the optical quality of different powers of ICLs, we analyzed the root mean square (RMS) of total higher order aberrations (HOAs), trefoil, coma, tetrafoil, secondary astigmatism, and spherical aberration at 3- and 4.5-mm pupil. In addition, the point spread functions (PSFs) of each ICL evaluated were ca…

Mesoangioblast stem cells membrane vesicles are carriers for molecules involved in autocrine and paracrine signals

2015

Architecture of dissonance : a study on the strategic management process of higher education internationalization

2018

In this study I analyze the neglected notion of organizational architecture in the strategic process of internationalization in the context of higher education. I examine the internationalization process through the development and management of international master’s degree programmes and their relation to the broader strategy of one particular Finnish university. I interviewed acting coordinators and directors of the programmes regarding their view on the administrative work, as well as the structures and resources, related to the programmes. Strategy documents, internal evaluations, and statistics were also analyzed. The omission of an explicit strategy and strategic program for internat…

Conception de documents numériques : Parcours méthodologique

2009

There is a strong social demand for studies of digital document. Yet our models of society and education are struggling to integrate issues related to these types of documents. However, the subject is less than half a century old, and so it is hardly surprising that the writing and training practices are just being developed. Like the book, the digital document involves many different skills and techniques in its development. The list of jobs tends to grow steadily: ergonomists, referencing specialists, information architects, programmers, designers, integrators ... It is therefore difficult to have a global view on all this know-how and the related methodologies. This special edition seeks…

Design, synthesis and structure-activity relationship of 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]furan derivatives as a novel class of inhibitors of t…

2009

The biological importance of microtubules in mitosis and cell division makes them an interesting target for the development of anticancer agents. Small molecules such as benzo[b]furans are attractive as inhibitors of tubulin polymerization. Thus, a new class of inhibitors of tubulin polymerization based on the 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[b]furan molecular skeleton, with electron-donating (Me, OMe or OH) or electron-withdrawing (F, Cl and Br) substituents on the benzene ring, was synthesized and evaluated for antiproliferative activity, inhibition of tubulin polymerization and cell cycle effects. Adding a methyl group at the C-3 position resulted in increased activity. The most prom…

Towards a Guidance System to Aid in the Dosimetry Calculation of Intraoperative Electron Radiation Therapy

2015

In Intraoperative Electron Radiation Therapy (IOERT), the lack of specific planning tools limits its applicability, the need for accurate dosimetry estimation and application during the therapy being the most critical. Recently, some works have been presented that try to overcome some of the limitations for establishing planning tools, though still an accurate guidance system that tracks, in real-time, the applicator and the patient is needed. In these surgical environments, the acquisition of an accurate 3D shape of the patient’s tumor bed in real-time is of high interest, as current systems make use of a 3D model acquired before the treatment. In this paper, an optical-based system is pre…

Effect of two distinct implant macro-designs on the osseointegration of bicortically installed implants in two topographic sites. A histomorphometric…

2019

Antecedentes científicos y objetivos de estudio: El uso de implantes dentales como alternativa para la rehabilitación oral ha demostrado su eficacia y mostrando altas tasas de supervivencia. Un aspecto clave de la osteointegración del implante dental está relacionado con la obtención de una estabilidad primaria adecuada, asegurada por el enclavamiento mecánico entre el tejido óseo y la interfaz del implante, la cual depende en parte de la geometría del implante, la rugosidad de la superficie y la técnica quirúrgica para la preparación del lecho implantario. Varios factores están involucrados en la interacción entre la superficie del implante y el hueso nativo circundante durante la osteoint…

The balance model of honest sexual signaling

2022

Costly signalling theory is based on the idea that individuals may signal their quality to potential mates and that the signal's costliness plays a crucial role in maintaining information content (‘honesty’) over evolutionary time. Whereas costly signals have traditionally been described as ‘handicaps’, here we present mathematical results that motivate an alternative interpretation. We show that under broad conditions, the multiplicative nature of fitness selects for roughly balanced investments in mating success and viability, thereby generating a positive correlation between signal size and quality. This balancing tendency occurs because selection for increased investment in a fitness co…

Sulfonamide moiety as "molecular chimera" in the design of new drugs.

2021

Background: The -SO2NH- group is of great significance in modern pharmaceutical use since, in sulfa-drugs, it is possible to introduce easily chemical modifications, and even small changes may lead to an improved version of an already existing drug. Objective: This paper aims to describe updated information in the sulfonamide field with a particular focus on new mechanisms of action, especially if discovered by employing computational approaches. Methods: Research articles that focused on the use of the sulfonamide moiety for the design, synthesis, and in vitro/in vivo tests of various diseases were collected from various search engines like PubMed, Science Direct, Google Scholar, and Scop…