Search results for "Signs and Symptoms"

showing 10 items of 178 documents

Patients' and physicians' preferences for type 2 diabetes mellitus treatments in Spain and Portugal: a discrete choice experiment.

2015

Objective: To assess Spanish and Portuguese patients' and physicians' preferences regarding type 2 diabetes mellitus (T2DM) treatments and the monthly willingness to pay (WTP) to gain benefits or avoid side effects. Methods: An observational, multicenter, exploratory study focused on routine clinical practice in Spain and Portugal. Physicians were recruited from multiple hospitals and outpatient clinics, while patients were recruited from eleven centers operating in the public health care system in different autonomous communities in Spain and Portugal. Preferences were measured via a discrete choice experiment by rating multiple T2DM medication attributes. Data were analyzed using the cond…

:Geographicals::Geographic Locations::Europe::Portugal [Medical Subject Headings]cardiovascular riskHbA1cendocrine system diseases:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index [Medical Subject Headings]:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Hypoglycemia [Medical Subject Headings]:Disciplines and Occupations::Health Occupations::Medicine::Public Health [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]:Named Groups::Persons::Occupational Groups::Health Personnel::Physicians [Medical Subject Headings]HbA(1c)HbA:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Body Weight Changes::Weight Loss [Medical Subject Headings]:Diseases::Cardiovascular Diseases [Medical Subject Headings]preferences:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]diabetesnutritional and metabolic diseasesPeso corporalweightPérdida de peso:Health Care::Health Care Facilities Manpower and Services::Health Facilities::Ambulatory Care Facilities [Medical Subject Headings]Diabetes mellitus tipo 2:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Signs and Symptoms Digestive::Nausea [Medical Subject Headings]hypoglycemia:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight [Medical Subject Headings]:Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus Type 2 [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Hypoglycemic Agents [Medical Subject Headings]Enfermedades cardiovascularesHipoglucemiawillingness to pay:Check Tags [Medical Subject Headings]discrete choice model
researchProduct

Pain Neuroscience Education and Physical Therapeutic Exercise for Patients with Chronic Spinal Pain in Spanish Physiotherapy Primary Care: A Pragmati…

2020

Producción Científica

:Health Care::Health Services Administration::Patient Care Management::Delivery of Health Care [Medical Subject Headings]lcsh:MedicineChronic painEnsayo clínico controlado aleatoriolaw.invention:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Nervous System Physiological Phenomena::Central Nervous System Sensitization [Medical Subject Headings]0302 clinical medicineRandomized controlled triallawphysical exerciseNeuroscience educationHealth care:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor Activity [Medical Subject Headings]030212 general & internal medicine:Health Care::Population Characteristics::Health::Mental Health [Medical Subject Headings]education.field_of_study:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Neurologic Manifestations::Pain::Chronic Pain [Medical Subject Headings]Chronic pain:Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Nervous System Physiological Phenomena::Nervous System Physiological Processes::Sensation::Pain::Pain Threshold [Medical Subject Headings]General MedicinePrimary care:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Personal Satisfaction [Medical Subject Headings]Ejercicio físico:Health Care::Health Services Administration::Patient Care Management::Comprehensive Health Care::Primary Health Care [Medical Subject Headings]Randomized controlled trialchronic painchronic spinal painmedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Methods::Research Design::Control Groups [Medical Subject Headings]PopulationChronic spinal painPhysical exerciseArticleEducación neurocientífica03 medical and health sciencesprimary careQuality of life (healthcare)medicine:Humanities::Humanities::Philosophy::Life::Quality of Life [Medical Subject Headings]educationpain neuroscience educationPain neuroscience educationbusiness.industry:Diseases::Musculoskeletal Diseases::Muscular Diseases::Musculoskeletal Pain [Medical Subject Headings]Public healthlcsh:RPhysical exerciseDolor crónicoAtención primariamedicine.diseaseClinical trialrandomized controlled trialPhysical therapy:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Neurologic Examination::Pain Measurement [Medical Subject Headings]businessNeuroscience030217 neurology & neurosurgeryJournal of Clinical Medicine
researchProduct

Assessment of brainstem function in Chiari II malformation utilizing brainstem auditory evoked potentials (BAEP), blink reflex and masseter reflex

2000

Brainstem dysfunction was evaluated in 67 patients with myelomeningocele and Chiari II malformation using brainstem auditory evoked potentials (BAEP), blink reflex (BR) and masseter reflex (MR). Signs and symptoms related to Chiari II malformation were observed in 18 patients while 49 patients had normal brainstem findings. BAEP and BR showed a higher sensitivity of brainstem involvement than MR (BAEP=1.0, BR=0.83, MR=0.50). BR, and in particular, MR were of higher accuracy (BR=0.52, MR=0.72) than BAEP (0.39) in separating patients with brainstem signs and symptoms related to Chiari II malformation. We feel that this is due to anatomic and physiologic peculiarities of the brainstem structur…

AdultMaleMeningomyeloceleAdolescentgenetic structuresCentral nervous systemSigns and symptomsSensitivity and SpecificityCentral nervous system diseaseDevelopmental NeuroscienceReflexEvoked Potentials Auditory Brain Stemotorhinolaryngologic diseasesmedicineHumansCorneal reflexChildBlinkingMasseter Musclebusiness.industryGeneral Medicinemedicine.diseaseArnold-Chiari Malformationmedicine.anatomical_structureChild PreschoolAnesthesiaPediatrics Perinatology and Child HealthReflexFemaleNeurology (clinical)BrainstembusinessJaw jerk reflexNormal brainstemBrain StemHydrocephalusBrain and Development
researchProduct

The spontaneous burst activity of peripheral blood monocytes in patients with acute polyradiculoneuritis, lymphocytic meningoencephalitis, and multip…

1986

Abstract The course of the spontaneous burst activity (BA) of peripheral blood monocytes was examined in patients with acute polyradiculoneuritis (PN), lymphocytic meningoencephalitis (LE), and multiple sclerosis (MS) and the BA was compared with the clinical course. In 4 patients with postinfectious acute PN the BA was significantly increased up to values around 60000 counts/10 s. The BA and the clinical course were closely correlated in these patients (mean of r = 0.83). In 4 patients with lymphocytic LE the BA initially was moderately increased to values between 4000 and 5000 counts/10 s and showed again a very close correlation with the clinical course (mean of r = 0.99) In 13 MS patien…

AdultMalePathologymedicine.medical_specialtyMultiple SclerosisAdolescentPolyradiculoneuropathySigns and symptomsMonocytesMeningoencephalitisHumansMedicineIn patientLymphocytesbusiness.industryMultiple sclerosisClinical courseMiddle Agedmedicine.diseasePeripheral bloodLymphocytic meningoencephalitisNeurologyAcute DiseaseLuminescent MeasurementsFemaleNeurology (clinical)businessJournal of the Neurological Sciences
researchProduct

Acute effects of strength exercises and effects of regular strength training on cell free DNA concentrations in blood plasma.

2017

Creatine kinase (CK) is a marker for muscle cell damage with limited potential as marker for training load in strength training. Recent exercise studies identified cell free DNA (cfDNA) as a marker for aseptic inflammation and cell damage. Here we overserved in a pilot study the acute effects during strength exercise and chronic effects of regular strength training on cfDNA concentrations over a period of four weeks in three training groups applying conservation training (CT) at 60% of the 1 repetition maximum, high intensity-low repetition training (HT) at 90% of the 1 repetition maximum and differential training (DT) at 60% of the 1 repetition maximum. EDTA-plasma samples were collected b…

AdultMalePhysiologyeducationImmunologylcsh:MedicinePilot ProjectsPathology and Laboratory Medicine796 Athletic and outdoor sports and gamesBlood PlasmaYoung AdultSigns and SymptomsDiagnostic MedicineMedicine and Health SciencesHumansPublic and Occupational HealthSports and Exercise Medicinelcsh:ScienceCreatine KinaseExerciseImmune ResponseInflammation796 SportCell-Free SystemOrganic Compoundslcsh:ROrganic ChemistryChemical CompoundsBiology and Life SciencesResistance TrainingDNAPhysical ActivityCreatineAdaptation PhysiologicalSports ScienceBody FluidsCapillariesChemistryBloodPhysical FitnessStrength TrainingPhysical SciencesPhysical EnduranceCardiovascular AnatomyBlood Vesselslcsh:QAnatomyDNA DamageResearch ArticlePloS one
researchProduct

The Decreasing Prevalence of the Arcuate Foramen

2018

[Background]: The arcuate foramen (AF), or ponticulus posticus, is an anatomic variant of the first cervical vertebra that consists of a complete or partial osseous bridge over the groove for the vertebral artery and extends from the posterior aspect of the superior articular facet to the superior lateral border of the posterior arch. The AF has been associated with clinical symptoms, such as headache, migraine, neck pain, shoulder pain, arm pain, and vertebral artery dissection. We aimed to test whether the prevalence of the AF has decreased in the modern human population over the past centuries as a result of reduction in inbreeding and endogamy.

AdultMaleRural Populationmusculoskeletal diseases0301 basic medicinemedicine.medical_specialtyUrban PopulationVertebral artery dissectionVertebral arteryPopulationConsanguinityYoung Adult03 medical and health sciences0302 clinical medicinemedicine.arteryHumansMedicineProspective StudiesVertebral arteryeducationSigns and symptomsAgedAged 80 and overArcuate forameneducation.field_of_studyNeck painbusiness.industryAnatomic VariationMiddle Agedmusculoskeletal systemmedicine.diseaseConfidence intervalSpineSurgeryBridge (graph theory)ArchaeologyMigraineRisk factorsCervical atlasFemaleSurgery030101 anatomy & morphologyNeurology (clinical)medicine.symptomAnatomybusiness030217 neurology & neurosurgery
researchProduct

Proposal for a new staging system for osteoradionecrosis of the mandible

2014

A new staging system for osteoradionecrosis of the mandible has been retrospectively applied to a group of 31 patients. In this system clinicoradiographic signs and symptoms are incorporated in a simplified manner. For imaging purposes the use of plain radiographs such as periapical films and panoramic radiographs is recommended, mainly because of their readily availability. The presented staging system seems well reproducible, facilitating the comparison of study groups dealing with the various issues of osteoradionecrosis of the mandible. It is yet to be evaluated whether the presently proposed staging system is useful for management purposes. Key words:Osteoradionecrosis, jaw bones, mand…

AdultMaleStudy groupsOsteoradionecrosisRadiographyDentistrySigns and symptomsOdontologíaSeverity of Illness IndexSDG 3 - Good Health and Well-beingmedicineHumansMandibular DiseasesGeneral DentistryStaging systemAgedRetrospective StudiesAged 80 and overOrthodonticsOral Medicine and Pathologybusiness.industryResearchMandibleMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOsteoradionecrosisOtorhinolaryngologyMandibular DiseasesUNESCO::CIENCIAS MÉDICAS/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleSurgeryPlain radiographsbusiness
researchProduct

Complex regional pain syndrome: evidence for warm and cold subtypes in a large prospective clinical sample.

2016

Limited research suggests that there may be Warm complex regional pain syndrome (CRPS) and Cold CRPS subtypes, with inflammatory mechanisms contributing most strongly to the former. This study for the first time used an unbiased statistical pattern recognition technique to evaluate whether distinct Warm vs Cold CRPS subtypes can be discerned in the clinical population. An international, multisite study was conducted using standardized procedures to evaluate signs and symptoms in 152 patients with clinical CRPS at baseline, with 3-month follow-up evaluations in 112 of these patients. Two-step cluster analysis using automated cluster selection identified a 2-cluster solution as optimal. Resul…

AdultMalemedicine.medical_specialtyDatabases FactualPopulationStatistical patternSigns and symptoms610 Medicine & health03 medical and health sciences0302 clinical medicine030202 anesthesiologyInternal medicinemedicineHumansIn patientProspective StudieseducationProspective cohort studyPain MeasurementInflammationeducation.field_of_studyPain durationbusiness.industry10051 Rheumatology Clinic and Institute of Physical MedicineMiddle Agedmedicine.diseaseAnesthesiology and Pain MedicineComplex regional pain syndrome2728 Neurology (clinical)PhenotypeNeurologyAnesthesia2808 Neurology10046 Balgrist University Hospital Swiss Spinal Cord Injury CenterFemaleNeurology (clinical)2703 Anesthesiology and Pain Medicinebusiness030217 neurology & neurosurgeryComplex Regional Pain SyndromesPain
researchProduct

Alterations in speech and voice in patients with mucopolysaccharidoses.

2013

The mucopolysaccharidoses are a group of lysosomal disorders characterized by abnormal accumulation of glycosaminoglycans within cell lysosomes leading to a variety of signs and symptoms including alterations in speech and voice production. These changes were analysed in 44 patients with mucopolysaccharidosis (MPS) types I, II, and VI using standardized protocols. Compared to healthy individuals the diadochokinetic rate for the fast repetition of syllables was slower and more irregular, the voice-onset time for the voiceless consonant /p/ was shorter, and most patients had a hoarse voice. The fundamental frequency (F0) of sustained spoken vowels was in the normal range for most women and ch…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentVoice QualityMucopolysaccharidosisSigns and symptomsAudiologySpeech AcousticsSpeech and HearingYoung AdultSex FactorsArts and Humanities (miscellaneous)PhonationSpeech Production MeasurementmedicineHumansIn patientChildHoarsenessVoice Disordersbusiness.industryVoice-onset timeEnzyme replacement therapyAcousticsMiddle AgedMucopolysaccharidosesLPN and LVNVoice productionmedicine.diseaseHoarse voiceCase-Control StudiesChild PreschoolVoiceAudiometry Pure-ToneFemalemedicine.symptombusinessLogopedics, phoniatrics, vocology
researchProduct

Somatosensory evoked potentials in Arnold-Chiari malformation.

2002

Abstract Nearly all patients with repaired myelomeningoceles have an Arnold–Chiari (AC) malformation and about 20% of these patients develop clinical signs of brainstem dysfunction. The management of symptomatic AC malformation is still controversial and techniques are needed to provide an objective assessment of brainstem function. We recorded somatosensory evoked potentials (SEPs) in 52 patients aged between 8 months and 20 years (median 7.3 years) with AC malformation, to determine whether the SEPs discriminate patients with symptomatic AC malformation from those without symptoms. The subcortical far-field components P13, P14 and N18, which are generated within the brainstem, were record…

AdultYounger ageMeningomyeloceleAdolescentNeural ConductionSigns and symptomsLate onsetSomatosensory systemSensitivity and SpecificityDevelopmental NeurosciencePredictive Value of TestsEvoked Potentials SomatosensoryMedicineHumansIn patientChildbusiness.industryInfantReproducibility of ResultsGeneral MedicineArnold-Chiari MalformationSpinal CordSomatosensory evoked potentialAnesthesiaChild PreschoolPediatrics Perinatology and Child HealthNeurology (clinical)BrainstemArnold chiaribusinessBrain StemBraindevelopment
researchProduct