Search results for "Silicon"

Highly selective and sensitive chromo-fluorogenic detection of the Tetryl explosive using functional silica nanoparticles

2011

Silica nanoparticles containing polyamines and thiol groups have been used as probes for the selective detection of Tetryl. © 2011 The Royal Society of Chemistry.

Extracting parameters from semi-log plots of polycrystalline silicon PV modules outdoor I–V data: Double-exponential model revisited

2010

This paper presents a method for extracting physically meaningful parameters from measured I–V curves of PV modules. The 7-parameter double-exponential model is applied in the modeling. The method is based on linear fitting of semi-logarithmic plots. The paper demonstrates a new technique to estimate the series resistance of a module with high accuracy from such plots. As a result, also the reverse saturation current and the quality factor of the diffusion diode can be determined. The method is applied to outdoor I–V data from a test station with three similar, but not identical, polycrystalline-Si modules. The values of the series resistances found with this method deviate somewhat from th…

Elastomeric Organosilicon Micronetworks

1997

Trifunctional methyltrimethoxysilane and bifunctional dimethyldimethoxysilane monomers were cocondensed in water in the presence of surfactant. Strictly spherical micronetworks of narrow size distribution were obtained for particle sizes 10 nm < R < 30 nm. By special “endcapping” reactions all reactive SiOH groups were removed quantitatively, and the resulting micronetworks become soluble in common organic solvents like toluene, THF, or chloroform. For contents of trifunctional monomer larger than 50 mol % the particles do not swell irrespective of the choice of the solvent, whereas for lower mole fractions of trimethoxysilane an increasing swelling ratio is observed. Below 2.5 mol % trifun…

Plasma Polymer Membranes for Immobilising Metalloporphyrins

2013

Atmospheric pressure dielectric barrier discharge formation of organosilicon thin films loaded with zinc 5,10,15,20-tetraphenylporphyrin (Zn(TPP)) was investigated for different deposition conditions. UV–visible spectroscopy and scanning electron microscopy revealed the effects of the metalloporpyhrins injection parameters and the plasma polymerisation conditions can affect the dispersion of the metalloporphyrins and the morphology of the coatings. The stability of the embedded Zn(TPP) molecules was investigated by orbitrap mass spectrometry.

Surface molecularly imprinted silica for selective solid-phase extraction of biochanin A, daidzein and genistein from urine samples

2015

Selective molecularly imprinted silica polymer (SiO2MIP) for extraction of biochanin A, daidzein and genistein was synthesized using the surface molecular imprinting technique with the silica gel as a support. Biochanin A (BCA) was used as a template, 3-aminopropyltriethoxysilane (APTES) as a functional monomer, and tetraethoxysilicane (TEOS) as a cross-linker. Non-imprinted polymer with the sol–gel process (SiO2NIP) was also prepared for comparison. The synthesized polymers were characterized by Fourier transform infrared spectrometry (FTIR), scanning electron microscopy (SEM) and a standard Brunauer-Emett-Teller (BET) and Barret–Joyner–Halenda (BJH) analysis. The obtained results indicate…

Selective chemisorption of carbon monoxide by organic-inorganic hybrid materials incorporating cobalt(III) corroles as sensing components.

2007

Twenty-one hybrid materials incorporating cobalt(III) corrole complexes were synthesized by a sol–gel process or by grafting the metallocorrole onto a mesostructured silica of the SBA-15 type. All the materials show an almost infinite selectivity for carbon monoxide with respect to dinitrogen and dioxygen in the low-pressure domain where the chemisorption phenomenon is predominant. This peculiar property is of prime importance for an application as a CO sensor. The selectivity slightly decreases at high pressures where nonselective physisorption phenomena mainly occur. The percentage of active sites for CO chemisorption ranges from 22 to 64 %. This low percentage may be attributable to inte…

Multifunctional hybrid Polyoxometalates for silicone gels with improved thermal and mechanical properties

2014

Caspase 3 Targeted Cargo Delivery in Apoptotic Cells Using Capped Mesoporous Silica Nanoparticles

2015

[EN] Excessive apoptotic cell death is at the origin of several pathologies, such as degenerative disorders, stroke or ischemia-reperfusion damage. In this context, strategies to improve inhibition of apoptosis and other types of cell death are of interest and may represent a pharmacological opportunity for the treatment of cell-death-related disorders. In this scenario new peptide-containing delivery systems (solids S1-P1and S1-P2) are described based on meso-porous silica nanoparticles (MSNs) loaded with a dye and capped with the KKGDEVDKKARDEVDK (P1) peptide that contains two repeats of the DEVD target sequence that are selectively hydrolyzed by caspase3 (C3). This enzyme plays a central…

Immunoproteasome and Non-Covalent Inhibition: Exploration by Advanced Molecular Dynamics and Docking Methods

2021

The selective inhibition of immunoproteasome is a valuable strategy to treat autoimmune, inflammatory diseases, and hematologic malignancies. Recently, a new series of amide derivatives as non-covalent inhibitors of the β1i subunit with Ki values in the low/submicromolar ranges have been identified. Here, we investigated the binding mechanism of the most potent and selective inhibitor, N-benzyl-2-(2-oxopyridin-1(2H)-yl)propanamide (1), to elucidate the steps from the ligand entrance into the binding pocket to the ligand-induced conformational changes. We carried out a total of 400 ns of MD-binding analyses, followed by 200 ns of plain MD. The trajectories clustering allowed identifying thre…

Ultrahigh-Throughput Proteomics Using Fast RPLC Separations with ESI-MS/MS

2005

We describe approaches for proteomics analysis using electrospray ionization-tandem mass spectrometry coupled with fast reversed-phase liquid chromatography (RPLC) separations. The RPLC separations used 50-microm-i.d. fused-silica capillaries packed with submicrometer-sized C18-bonded porous silica particles and achieved peak capacities of 130-420 for analytes from proteome tryptic digests. When these separations were combined with linear ion trap tandem mass spectrometry measurements, approximately 1000 proteins could be identified in 50 min from approximately 4000 identified tryptic peptides; approximately 550 proteins in 20 min from approximately 1800 peptides; and approximately 250 prot…