Search results for "Simulation."
showing 10 items of 4779 documents
MMGBSA As a Tool To Understand the Binding Affinities of Filamin–Peptide Interactions
2013
Filamins (FLN) are large dimeric proteins that cross-link actin and work as important scaffolds in human cells. FLNs consist of an N-terminal actin-binding domain followed by 24 immunoglobulin-like domains (FLN1-24). FLN domains are divided into four subgroups based on their amino acid sequences. One of these subgroups, including domains 4, 9, 12, 17, 19, 21, and 23, shares a similar ligand-binding site between the β strands C and D. Several proteins, such as integrins β2 and β7, glycoprotein Ibα (GPIbα), and migfilin, have been shown to bind to this site. Here, we computationally estimated the binding free energies of filamin A (FLNa) subunits with bound peptides using the molecular mechan…
Topology management in unstructured P2P networks using neural networks
2007
Resource discovery is an essential problem in peer-to-peer networks since there is no centralized index in which to look for information about resources. In a pure P2P network peers act as servers and clients at the same time and in the Gnutella network for example, peers know only their neighbors. In addition to developing different kinds of resource discovery algorithms, one approach is to study the different topologies or structures of the P2P network. In many cases topology management is based on either technical characteristics of the peers or their interests based on the previous resource queries. In this paper, we propose a topology management algorithm which does not predetermine fa…
Attracting sets in network regulatory theory
2016
Modern telecommunication networks are very complex and they should be able to deal with rapid and unpredictable changes in traffic flows. Virtual Network Topology is used to carry IP traffic over Wavelength-division multiplexing optical network. To use network resources in the most optimal way, there is a need for an algorithm, which will dynamically re-share resources among all devices in the particular network segment, based on links utilization between routers. Attractor selection mechanism could be used to dynamically control such Virtual Network Topology. The advantage of this algorithm is that it can adopt to very rapid, unknown and unpredictable changes in traffic flows. This mechani…
A Logical Architecture for Active Network Management
2006
This paper focuses on improving network management by exploiting the potential of “doing” of the Active Networks technology, together with the potential of “planning,” which is typical of the artificial intelligent systems. We propose a distributed multiagent architecture for Active Network management, which exploits the dynamic reasoning capabilities of the Situation Calculus in order to emulate the reactive behavior of a human expert to fault situations. The information related to network events is generated by programmable sensors deployed across the network. A logical entity collects this information, in order to merge it with general domain knowledge, with a view to identifying the roo…
A SIMPLE PARTICLE MODEL FOR A SYSTEM OF COUPLED EQUATIONS WITH ABSORBING COLLISION TERM
2011
We study a particle model for a simple system of partial differential equations describing, in dimension $d\geq 2$, a two component mixture where light particles move in a medium of absorbing, fixed obstacles; the system consists in a transport and a reaction equation coupled through pure absorption collision terms. We consider a particle system where the obstacles, of radius $\var$, become inactive at a rate related to the number of light particles travelling in their range of influence at a given time and the light particles are instantaneously absorbed at the first time they meet the physical boundary of an obstacle; elements belonging to the same species do not interact among themselves…
A Pedagogical Software for the Analysis of Loudspeaker Systems
2009
In this paper, a pedagogical software for the design and analysis of loudspeaker systems is presented, with emphasis on training students in the interaction between system parameters. Loudspeakers are complex electromechanical system, whose behavior is neither intuitive nor easy to understand by inexperienced students. Although commercial simulation software provides computation of the equations governing loudspeaker systems, they are mainly focused on the final product and are intended for experienced audio engineers. The proposed software was intentionally designed for education and training purposes. This software allows students to investigate loudspeaker systems that involve complex in…
Generating harmonic surfaces for interactive design
2014
Abstract A method is given for generating harmonic tensor product Bezier surfaces and the explicit expression of each point in the control net is provided as a linear combination of prescribed boundary control points. The matrix of scalar coefficients of these combinations works like a mould for harmonic surfaces. Thus, real-time manipulation of the resulting surfaces subject to modification of prescribed information is possible.
Acoustic rendering of particle-based simulation of liquids in motion
2009
In interaction and interface design, the representation of continuous processes often uses liquid metaphors, such as dripping or streaming. When an auditory display of such processes is required, an approach to sound-synthesis based on the physics of liquids in motion would be the most convincing, especially when real-time interaction is into play. In order to bridge the complexity of fluid-dynamic simulations with the needs of interactive sonification, we propose a multi-rate sound synthesis of liquid phenomena. Low-rate smoothed-particle hydrodynamics is used to model liquids in motion and to trigger sound-emitting events. Such events, such as solid-liquid collision, or bubble formation, …
Analysis of the new submarine interconnection system between Italy and Malta: Simulation of transmission network operation
2016
In this paper, some simulations of the interconnected Sicilian and Maltese transmission systems are performed, in order to assess this new system configuration. The HVAC submarine interconnection between Italy and Malta came into operation in 2015 and is part of a European programme for transmission grid interconnection improvement. This new line has been built in order to allow a better management of the power system of both the islands. Firstly, a brief description of the interconnection system is given. Moreover, the transmission systems of Sicily and Malta are depicted and their structures are shown. The simulations are carried out by means of a model of the interconnected system create…
VEF Traces: A Framework for Modelling MPI Traffic in Interconnection Network Simulators
2015
Simulation is often used to evaluate the behaviour and measure the performance of computing systems. Specifically, in high-performance interconnection networks, the simulation has been extensively considered to verify the behaviour of the network itself and to evaluate its performance. In this context, network simulation must be fed with network traffic, also referred to as network workload, whose nature has been traditionally synthetic. These workloads can be used for the purpose of driving studies on network performance, but often such workloads are not accurate enough if a realistic evaluation is pursued. For this reason, other non-synthetic workloads have gained popularity over last dec…