Search results for "Simulation."
showing 10 items of 4779 documents
Photoactivation of Drosophila melanogaster cryptochrome through sequential conformational transitions
2019
Time-resolved x-ray scattering reveals light-induced signal transduction in insect cryptochromes.
Experimental signature of optical wave thermalization through supercontinuum generation in photonic crystal fiber
2009
International audience; We report an experimental, numerical and theoretical study of the incoherent regime of supercontinuum generation in a two zero dispersion wavelengths fiber. By using a simple experimental setup, we show that the phenomenon of spectral broadening inherent to supercontinuum generation can be described as a thermalization process, which is characterized by an irreversible evolution of the optical field towards a thermal equilibrium state. In particular, the thermodynamic equilibrium spectrum predicted by the kinetic wave theory is characterized by a double peak structure, which has been found in quantitative agreement with the numerical simulations without adjustable pa…
Spatio-Chromatic Adaptation via Higher-Order Canonical Correlation Analysis of Natural Images
2014
Independent component and canonical correlation analysis are two general-purpose statistical methods with wide applicability. In neuroscience, independent component analysis of chromatic natural images explains the spatio-chromatic structure of primary cortical receptive fields in terms of properties of the visual environment. Canonical correlation analysis explains similarly chromatic adaptation to different illuminations. But, as we show in this paper, neither of the two methods generalizes well to explain both spatio-chromatic processing and adaptation at the same time. We propose a statistical method which combines the desirable properties of independent component and canonical correlat…
Predictive First-Principles Modeling of a Photosynthetic Antenna Protein: The Fenna–Matthews–Olson Complex
2020
High efficiency of light harvesting in photosynthetic pigment–protein complexes is governed by evolutionary-perfected protein-assisted tuning of individual pigment properties and interpigment interactions. Due to the large number of spectrally overlapping pigments in a typical photosynthetic complex, experimental methods often fail to unambiguously identify individual chromophore properties. Here, we report a first-principles-based modeling protocol capable of predicting properties of pigments in protein environment to a high precision. The technique was applied to successfully uncover electronic properties of the Fenna–Matthews–Olson (FMO) pigment–protein complex. Each of the three subunit…
Implementations of a novel algorithm for colour constancy
1997
AbstractIn agreement with the principles of the relativistic model proposed by Creutzfeldtet al., with the photometric rule (lightness anchoring rule) and with the influence of simultaneous contrast in the appearance of a visual scene, we propose a first-stage mechanism yielding substantial colour constancy. We have defined a set of first-stage colour descriptors, and to test their utility, we have performed a simulation using a Machine Vision System (MVS). The statistical stability of the descriptors for Munsell samples under different illuminants is good.
Innovative straight formulation for plate in bending
2017
In this paper it has been introduced an innovative formulation for evaluating the deflection function of a simply supported plate loaded by uniformly distributed edge moments. Framed into Line Element-less Method, this formulation allows the evaluation of solution in terms of deflection, through few lines of algorithm implemented by Mathematica software without resorting to any discretization neither in the domain nor in the boundary. Interesting savings in terms of time and computational costs are achieved. Results obtained by the proposed method are well contrasted by ones obtained by classical methods and Finite Element Method.
A new OLS-based procedure for clusterwise linear regression
2009
Data heterogeneity, within a (linear) regression framework, often suggests the use of a Clusterwise Linear Regression (CLR) procedure, which implies, among other things, the estimate of the appropriate number of clusters as well as the cluster membership of each unit. The approaches to the estimation of a CLR model are essentially based on the Ordinary Least Square (OLS) criterion or the likelihood criterion. In this paper, in a context of OLS approach, we propose an estimation of the model making use of an algorithm based on a threshold criterion for the determination coefficient of each cluster, to identify the appropriate number of clusters, and of a modified Spath's algorithm, to estima…
Cognitive factors in the evaluation of synthetic speech
1998
Abstract This paper illustrates the importance of various cognitive factors involved in perceiving and comprehending synthetic speech. It includes findings drawn from the relative psychological and psycholinguistic literature together with experimental results obtained at the Fondazione Ugo Bordoni laboratory. Overall, it is shown that listening to and comprehending synthetic voices is more difficult than with a natural voice. However, and more importantly, this difficulty can and does decrease with the subjects' exposure to said synthetic voices. Furthermore, greater workload demands are associated with synthetic speech and subjects listening to synthetic passages are required to pay more …
Modeling Listeners’ Emotional Response to Music
2012
An overview of the computational prediction of emotional responses to music is presented. Communication of emotions by music has received a great deal of attention during the last years and a large number of empirical studies have described the role of individual features (tempo, mode, articulation, timbre) in predicting the emotions suggested or invoked by the music. However, unlike the present work, relatively few studies have attempted to model continua of expressed emotions using a variety of musical features from audio-based representations in a correlation design. The construction of the computational model is divided into four separate phases, with a different focus for evaluation. T…
Accounting for haplotype phase uncertainty in linkage disequilibrium estimation
2007
The characterization of linkage disequilibrium (LD) is applied in a variety of studies including the identification of molecular determinants of the local recombination rate, the migration and population history of populations, and the role of positive selection in adaptation. LD suffers from the phase uncertainty of the haplotypes used in its calculation, which reflects limitations of the algorithms used for haplotype estimation. We introduce a LD calculation method, which deals with phase uncertainty by weighting all possible haplotype pairs according to their estimated probabilities as evaluated by PHASE. In contrast to the expectation-maximization (EM) algorithm as implemented in the HA…