Search results for "Simulation"
showing 10 items of 5095 documents
Energy modelling studies of thermochromic glazing
2010
Theoretically thermochromic glazing has the potential to reduce energy consumption in buildings by allowing visible light for day lighting, reducing unwanted solar gain during the cooling season, whilst allowing useful solar gain in the heating season. In this study building simulation is used to predict the savings made by novel thermochromic glazing coatings compared to standard products, for locations with different climates. The results suggest that thermochromic glazing can have a significant energy saving effect compared to current approaches.
A PHENOMENOLOGICAL OPERATOR DESCRIPTION OF INTERACTIONS BETWEEN POPULATIONS WITH APPLICATIONS TO MIGRATION
2013
We adopt an operatorial method based on the so-called creation, annihilation and number operators in the description of different systems in which two populations interact and move in a two-dimensional region. In particular, we discuss diffusion processes modeled by a quadratic hamiltonian. This general procedure will be adopted, in particular, in the description of migration phenomena. With respect to our previous analogous results, we use here fermionic operators since they automatically implement an upper bound for the population densities.
Immune activation promotes evolutionary conservation of T-cell epitopes in HIV-1.
2013
The immune system should constitute a strong selective pressure promoting viral genetic diversity and evolution. However, HIV shows lower sequence variability at T-cell epitopes than elsewhere in the genome, in contrast with other human RNA viruses. Here, we propose that epitope conservation is a consequence of the particular interactions established between HIV and the immune system. On one hand, epitope recognition triggers an anti-HIV response mediated by cytotoxic T-lymphocytes (CTLs), but on the other hand, activation of CD4(+) helper T lymphocytes (TH cells) promotes HIV replication. Mathematical modeling of these opposite selective forces revealed that selection at the intrapatient l…
Testing for goodness rather than lack of fit of an X–chromosomal SNP to the Hardy-Weinberg model
2019
The problem of checking the genotype distribution obtained for some diallelic marker for compatibility with the Hardy-Weinberg equilibrium (HWE) condition arises also for loci on the X chromosome. The possible genotypes depend on the sex of the individual in this case: for females, the genotype distribution is trinomial, as in the case of an autosomal locus, whereas a binomial proportion is observed for males. Like in genetic association studies with autosomal SNPs, interest is typically in establishing approximate compatibility of the observed genotype frequencies with HWE. This requires to replace traditional methods tailored for detecting lack of fit to the model with an equivalence test…
Computer-aided detection of cerebral microbleeds in susceptibility-weighted imaging.
2014
Susceptibility-weighted imaging (SWI) is recognized as the preferred MRI technique for visualizing cerebral vasculature and related pathologies such as cerebral microbleeds (CMBs). Manual identification of CMBs is time-consuming, has limited reliability and reproducibility, and is prone to misinterpretation. In this paper, a novel computer-aided microbleed detection technique based on machine learning is presented: First, spherical-like objects (potential CMB candidates) with their corresponding bounding boxes were detected using a novel multi-scale Laplacian of Gaussian technique. A set of robust 3-dimensional Radon- and Hessian-based shape descriptors within each bounding box were then ex…
Interactive simulation of one-dimensional flexible parts
2006
Computer simulations play an ever growing role for the development of automotive products. Assembly simulation, as well as many other processes, are used systematically even before the first physical prototype of a vehicle is built in order to check whether particular components can be assembled easily or whether another part is in the way. Usually, this kind of simulation is limited to rigid bodies. However, a vehicle contains a multitude of flexible parts of various types: cables, hoses, carpets, seat surfaces, insulations, weatherstrips... Since most of the problems using these simulations concern one-dimensional components and since an intuitive tool for cable routing is still needed, w…
A heuristic model-based approach for compensating wind effects in ski jumping.
2021
Wind influences the jump length in ski jumping, which raises questions about the fairness. To counteract the wind problem, the International Ski Federation has introduced a wind compensation system in 2009: time-averaged wind velocity components tangential to the landing slope are obtained from several sites along the landing slope, and these data are used in a linear statistical model for estimating the jump length effect of wind. This is considered in the total score of the ski jump. However, it has been shown that the jump length effect estimates can be inaccurate and misleading. The present manuscript introduces an alternative mathematical wind compensation approach that is based on an …
Advances in the enumeration of foldable self-avoiding walks
2020
<font color="#336633">Self-avoiding walks (SAWs) have been studied for a long time due to their intrinsic importance and the many application fields in which they operate. A new subset of SAWs, called foldable SAWs, has recently been discovered when investigating two different SAW manipulations embedded within existing protein structure prediction (PSP) software. Since then, several attempts have been made to find out more about these walks, including counting them. However, calculating the number of foldable SAWs appeared as a tough work, and current supercomputers fail to count foldable SAWs of length exceeding ≈ 30 steps. In this article, we present new progress in this enumeration, bo…
Advanced Stochastic Petri Net Modeling with the Mercury Scripting Language
2017
Formal models are widely used in performance and dependability studies of computational systems. Graphical modeling tools allow users to compose such models with ease, but they complicate the creation of models with a dynamic/complex structure, the hierarchical arrangement of different models, and the automatic execution of models with different parameter configurations. To overcome this problem, we created a scripting language for the Mercury tool that supports the combination of different modeling approaches (e.g., Stochastic Petri Nets and Reliability Block Diagrams) in a single project. In this paper, we focus on the extensions developed to improve the capabilities of Generalized Stocha…
Horizons: Nuclear Astrophysics in the 2020s and Beyond
2022
Nuclear astrophysics is a field at the intersection of nuclear physics and astrophysics, which seeks to understand the nuclear engines of astronomical objects and the origin of the chemical elements. This white paper summarizes progress and status of the field, the new open questions that have emerged, and the tremendous scientific opportunities that have opened up with major advances in capabilities across an ever growing number of disciplines and subfields that need to be integrated.We take a holistic view of the field discussing the unique challenges and opportunities in nuclear astrophysics in regards to science, diversity, education, and the interdisciplinarity and breadth of the field…