Search results for "Single equation"
showing 3 items of 13 documents
QSAR multi-target in drug discovery: a review.
2013
The main purpose of the present review is to summarize the most significant works up to date in the field of multi-target QSAR (mt-QSAR), in order to emphasize the importance that this technique has acquired over the last decade. Unlike traditional QSAR techniques, mt-QSAR permits to calculate the probability of activity of a given compound against different biological or pharmacological targets. In simple terms, a single equation for multiple outputs. To emphasize more the importance of the mt-QSAR in the field of drug discovery, we also present a novel mt-QSAR model, made on purpose by our research group, for the prediction of the susceptibility of Gram + and Gram - anaerobic bacteria.
Interactions, spillovers de connaissance et croissance des économies modernes. Faut-il préférer la globalisation ou la proximité géographique ?
2009
Globalisation and metropolisation in modern economies induce some locational strategies of knowledge based activities towards cities and deeply increase trade and move of ideas across cities. In that context, we study the way knowledge spillovers have influenced the economic growth of 82 European Metropolises over the 1990-2005 period. We model knowledge spillovers across cities according to three specific interaction patterns depending either on geography or on global advanced services or thought a combination of these patterns. We show that the mixed pattern matters the best for economic growth of cities in Europe.
Analysis of the determinants of entrepreneurial intention: the case of Burkina Faso
2018
International audience; In this study, we propose to analyze students' entrepreneurial intention, drawing on Lazear's (2004) self-selection model. This model captures the role of "human capital" in employment assignment and emphasizes the importance of the variety of skills in the individual's entrepreneurial orientation. For this purpose, we have a database collected in 2017 from over 1000 students at Ouaga I and Ouaga II universities in Burkina Faso. The results of estimates obtained using the quantile regression method show a positive and significant effect of the diversity of skills on the intention score, mainly at the median level. Even if the effect is not strong, this result support…