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showing 10 items of 4920 documents

Assessment of proneness to distraction: English adaptation and validation of the Attention-Related Driving Errors Scale (ARDES) and cross-cultural eq…

2016

Abstract Prior research developed the Attention-Related Driving Errors Scale (ARDES), a 19-item questionnaire aimed at evaluating the drivers’ predisposition to attentional error, and also provided validity evidence of ARDES measures across two countries: Argentina and Spain. In the current work we adapt the Spanish version of the ARDES to the English language and the culture, traffic regulations and driving habits of the UK, and then provide new evidence of the cross-cultural equivalence of the scale. First, an improved forward and backward translation design was used to translate the Spanish ARDES into English. A committee-approach review process was also performed during the translation …

050210 logistics & transportationPsychometrics05 social sciencesSingle factorApplied psychologyHuman errorTransportationCross cultural equivalenceEnglish languageCronbach's alphaDistraction0502 economics and businessAutomotive Engineering0501 psychology and cognitive sciencesPsychologySocial psychologyEquivalence (measure theory)050107 human factorsApplied PsychologyCivil and Structural EngineeringTransportation Research Part F: Traffic Psychology and Behaviour
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Base-Controlled Regiospecific Mono-Benzylation/Allylation and Diallylation of 4-Aryl-5-indolyl-1,2,4-triazole-3-thione : Thio-Aza Allyl Rearrangement

2023

The regiospecific S-benzylation/allylation of two 4-aryl-5-indolyl-1,2,4-triazole-3-thione precursors was carried out using Et3N as a base. Allyl group migration from exocyclic sulfur to the triazole nitrogen (N3) was successfully achieved in a short time via thermal fusion without the need for any catalyst. The allylation of indole nitrogen, along with exocyclic sulfur or triazole nitrogen (N3), was carried out using K2CO3 as stronger base. S,N-Diallylated products were converted to N,N-diallylated analogues using a simple fusion approach. Structural analyses of the two newly synthesized hybrids 2b and 5b investigated via the X-ray diffraction of a single crystal combined with Hirshfeld ca…

124-triazole-3-thioneX-ray single-crystal analysisthio-aza allyl rearrangementheterosykliset yhdisteetallylationorgaaniset yhdisteetröntgenkristallografia
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Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme

2018

Syphilis is an important public health problem and an increasing incidence has been noted in recent years. Characterization of strain diversity through molecular data plays a critical role in the epidemiological understanding of this re-emergence. We here propose a new high-resolution multilocus sequence typing (MLST) scheme for Treponema pallidum subsp. pallidum (TPA). We analyzed 30 complete and draft TPA genomes obtained directly from clinical samples or from rabbit propagated strains to identify suitable typing loci and tested the new scheme on 120 clinical samples collected in Switzerland and France. Our analyses yielded three loci with high discriminatory power: TP0136, TP0548, and TP…

10207 Department of AnthropologyArtificial Gene Amplification and ExtensionGene mutationPathology and Laboratory MedicineFrance/epidemiologyBiochemistryPolymerase Chain Reactionlaw.inventionSwitzerland/epidemiologylcsh:SciencePhylogenyMammalsBacterialEukaryotaGeneral MedicineMacrolides/pharmacologyMultilocus Sequence Typing/methods3. Good healthBacterial PathogensNucleic acidsMedical MicrobiologyLeporidsMacrolidesAlleles; Anti-Bacterial Agents/pharmacology; DNA Bacterial/genetics; France/epidemiology; Genome Bacterial; Genotype; Globus Pallidus; Macrolides/pharmacology; Multilocus Sequence Typing/methods; Phylogeny; Polymorphism Single Nucleotide; RNA Ribosomal 23S/genetics; Sequence Analysis DNA/methods; Switzerland/epidemiology; Syphilis/epidemiology; Treponema pallidum/geneticsGeneral Agricultural and Biological SciencesSwitzerlandGenotypeSequence analysis030106 microbiologySexually Transmitted Diseases1100 General Agricultural and Biological SciencesGlobus PallidusMicrobiologyAnti-Bacterial Agents/pharmacology10127 Institute of Evolutionary Biology and Environmental Studies03 medical and health sciences1300 General Biochemistry Genetics and Molecular Biology23S ribosomal RNAGeneticsTypingSyphilisPolymorphismNon-coding RNAMolecular Biology TechniquesMicrobial PathogensMolecular BiologyAllelesRibosomal1000 MultidisciplinaryGenitourinary Infectionslcsh:ROrganismsBiology and Life SciencesDNATropical DiseasesTreponema pallidum/genetics030104 developmental biologyGenetic LociGeneral Biochemistrylcsh:QMultilocus Sequence Typing0301 basic medicineBacterial DiseasesBacterial/geneticslcsh:MedicineTreponematosesGeographical LocationslawGenotypeMedicine and Health Sciences23S/geneticsTreponema PallidumPolymerase chain reactionGeneticsMultidisciplinaryTreponemaGenome10177 Dermatology ClinicSingle NucleotideAnimal Models10218 Institute of Legal MedicineAnti-Bacterial AgentsDNA/methodsEuropeRNA Ribosomal 23SInfectious DiseasesRibosomal RNAExperimental Organism SystemsVertebratesFranceRabbitsPathogensSequence AnalysisResearch ArticleNeglected Tropical DiseasesDNA BacterialCell biologyCellular structures and organellesUrology610 Medicine & healthGenetics and Molecular BiologyBiologyResearch and Analysis MethodsPolymorphism Single NucleotideAnimalsEuropean Unionddc:613Syphilis/epidemiologySequence Analysis DNAbiology.organism_classificationddc:616.8People and PlacesAmniotesMultilocus sequence typingRNARibosomesGenome BacterialPLoS ONE
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First measurement of the W-boson mass in run II of the Tevatron.

2007

7 pages, 4 figures.-- PACS nrs.: 14.70.Fm; 13.38.Be; 13.85.Qk.-- ISI Article Identifier: 000250140600014.-- ArXiv pre-print available at: http://arxiv.org/abs/0707.0085.-- et al.

13.38.Be 14.70.Fm 12.15.Ji 13.85.QkParticle physicsSingle measurementPhysics MultidisciplinaryTevatronFOS: Physical sciencesGeneral Physics and AstronomyElementary particleData recordingddc:500.201 natural sciencesParticle detectorHigh Energy Physics - ExperimentNuclear physicsHigh Energy Physics - Experiment (hep-ex)[PACS] Decays of W bosons0103 physical sciences[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]W-boson massFermilabMeasurement theory010306 general physicsNuclear Experiment[PACS] Hadron-induced inclusive production with identified leptons photons or other nonhadronic particles (energy > 10 GeV)BosonsBosonPhysics010308 nuclear & particles physicsPhysicsHigh Energy Physics::PhenomenologyDetectorsTevatron[PACS] W bosonsHigh Energy Physics::ExperimentBar (unit)
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Effects of clopidogrel, prasugrel and ticagrelor on endothelial function, inflammatory and oxidative stress parameters and platelet function in patie…

2014

Introduction Particularly in the setting of acute coronary syndromes, the interplay between vascular and platelet function has been postulated to have direct clinical implications. The present trial is designed to test the effect of clopidogrel, prasugrel and ticagrelor on multiple parameters of vascular function, platelet aggregation, oxidative and inflammatory stress before and up to 4 weeks after coronary artery stenting. Methods and analysis The study is designed as a three-arm, parallel design, randomised, investigator-blinded study. Patients with unstable angina or non-ST elevation myocardial infarction undergoing coronary intervention with a drug-eluting stent will be randomised to r…

1683AdultBlood PlateletsMaleTicagrelorAdenosineTiclopidineAdolescent610 MedizinCardiovascular MedicineYoung AdultPercutaneous Coronary Intervention610 Medical sciencesProtocolHumansSingle-Blind Method1506Prospective StudiesAcute Coronary Syndrome1707AgedDrug-Eluting StentsMiddle AgedClopidogrelOxidative StressTreatment OutcomePurinergic P2Y Receptor AntagonistsFemaleEndothelium VascularPrasugrel HydrochloridePlatelet Aggregation InhibitorsFollow-Up Studies
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Conformational properties of cyanomethoxy calix[4]arenes.

2005

O-Alkylation of the dinitro calix[4]arene 2, easily available by selective ipso-nitration of the di-cyanomethyl ether 1, with allylbromide (DMF/Cs2CO3) gave tetraethers 3 and 4 with anti- and syn-orientations of the two allyl ether residues. The two possible stereoisomers of 3 in the partial cone and 1,2-alternate conformation exist as an equilibrium mixture which could be quantitatively analysed by 1H NMR spectroscopy. The temperature dependence of this equilibrium leads to ΔH0 = − 7.6 to −9.7 kJ mol−1 in different solvents (tetrachloroethane, benzene, dimethylsulfoxide). Since 3(1,2-alt) could be obtained in pure form, its isomerisation to the equilibrium mixture with 3(paco) could be fol…

1h nmr spectroscopyChemistryOrganic ChemistryEtherActivation energyKinetic energyBiochemistryTetrachloroethanechemistry.chemical_compoundOrganic chemistryPhysical chemistryPhysical and Theoretical ChemistryBenzeneSingle crystalIsomerizationOrganicbiomolecular chemistry
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Genetic and Epigenetic Factors of Takotsubo Syndrome: A Systematic Review

2021

Takotsubo syndrome (TTS), recognized as stress’s cardiomyopathy, or as left ventricular apical balloon syndrome in recent years, is a rare pathology, described for the first time by Japanese researchers in 1990. TTS is characterized by an interindividual heterogeneity in onset and progression, and by strong predominance in postmenopausal women. The clear causes of these TTS features are uncertain, given the limited understanding of this intriguing syndrome until now. However, the increasing frequency of TTS cases in recent years, and particularly correlated to the SARS-CoV-2 pandemic, leads us to the imperative necessity both of a complete knowledge of TTS pathophysiology for identifying bi…

2019-20 coronavirus outbreakTTS managementCoronavirus disease 2019 (COVID-19)DNA Copy Number VariationsQH301-705.5Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Heart VentriclesReviewBioinformaticsPolymorphism Single NucleotideCatalysisEpigenesis GeneticInorganic ChemistryGenetic Heterogeneitysystematic reviewTakotsubo CardiomyopathyMedicineHumansGenetic Predisposition to DiseaseEpigeneticsTakotsubo cardiomyopathy (TTS)Biology (General)Physical and Theoretical ChemistryMedical History TakingQD1-999Molecular BiologySpectroscopyTakotsubo syndromePostmenopausal womenbusiness.industryGenetic heterogeneitySARS-CoV-2Organic ChemistrybiomarkersCOVID-19General Medicinespecific and effective treatmentsgenetic and epigenetic factorsComputer Science ApplicationsChemistrySettore MED/03Genetic LociIdentification (biology)businessInternational Journal of Molecular Sciences
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"Table 1" of "Measurement of direct photon pair production cross sections in ppbar collisions at sqrt(s)=1.96 TeV"

2010

Single differential cross section DSIG/DM.

20477612047661InclusiveSingle Differential Cross SectionDSIG/DMPBAR P --> GAMMA GAMMA X1960.0
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"Table 3" of "Measurement of direct photon pair production cross sections in ppbar collisions at sqrt(s)=1.96 TeV"

2010

Single differential cross section DSIG/DPHI.

20477612047661InclusiveSingle Differential Cross SectionDSIG/DPHIPBAR P --> GAMMA GAMMA XAzimuthal Angular Dependence1960.0
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"Table 4" of "Measurement of direct photon pair production cross sections in ppbar collisions at sqrt(s)=1.96 TeV"

2010

Single differential cross section DSIG/DCOS(THETA).

20477612047661InclusiveSingle Differential Cross SectionPBAR P --> GAMMA GAMMA X1960.0DSIG/DCOS(THETA)Angular Dependence
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