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showing 10 items of 4920 documents

Synthesis, characterization, crystal structures and biological screening of 4-amino quinazoline sulfonamide derivatives

2019

Three quinazolin-4-ylamino derivatives containing phenylbenzenesulfonamides (7a-7c) were synthesized by reacting (E)-N'-(2-cyanophenyl)-N,N-dimethyl formamidine (6) with different 4- amino-N-(phenyl)benzenesulfonamides (4a-4c) and characterized by different techniques such as HRMS, IR, 1H NMR and 13C NMR spectroscopy. The structural properties were further examined by single crystal X-ray diffraction method. The X-ray data shows that compounds 7a and 7c contain two molecules and 7b contains one molecule in the asymmetric unit. Comparison of conformation of two distinct molecules, “A” and “B”, in the asymmetric unit of 7a and 7c were studied with the aid of reported literature. The in vitro …

antiproliferative activitycrystal structurearomaattiset yhdisteetStereochemistryX-ray-diffractionCrystal structure010402 general chemistry01 natural sciencesAnalytical ChemistryInorganic Chemistrychemistry.chemical_compoundQuinazolineMoleculeta116Spectroscopychemistry.chemical_classificationantimikrobiset yhdisteetkemiallinen synteesi010405 organic chemistryOrganic Chemistryta1182Antimicrobialquinazoline-sulfonamide0104 chemical sciencesSulfonamidechemistryX-ray crystallographysolunsalpaajatProton NMRantimicrobialSingle crystal
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Snellimento dell'appello?

2021

The paper analyses the reform project on criminal process presented by the previous Minister of Justice "Bonafede", with particular regard to the appeal stage.

appealSettore IUS/16 - Diritto Processuale Penalesingle judgecamera proceeding
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Application Development from Prototype to Beta : A Case Study of the Application SeafarerCV

2018

Master's thesis Multimedia and Educational Technology MM500 - University of Agder 2018 When the prototype of a software product is completed and approved, development of a betaready resource is often the natural step toward a future final release. This process contains many steps that may prove vital to the eventual success or downfall of a future product. Technologies must be chosen, design methodologies must be followed, and care must be given to provide the final product with a solid foundation to build upon. This thesis follows such a development process for the development of resources for beta-testing. This process, as well as the human centered design approaches, and the resulting re…

application success factorshuman-centered designsingle authentication serviceMM500Application developmentdevelopment processVDP::Teknologi: 500::Informasjons- og kommunikasjonsteknologi: 550
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Theoretical and experimental studies of some main group compounds : from closed shell interactions to singlet diradicals and stable radicals

2012

Acquiring knowledge of different interactions within and between molecules is a fascinating undertaking as it not only deepens our understanding of chemical bonding but also offers insight into electronic structures, molecular properties and the connections between these two. This dissertation combines together three main group chemistry related topics within the aforementioned theme. Research presented in the first third of this dissertation describes wave function and density functional theory studies of weak inter- and intramolecular interactions in pnictogen-based dimers X3Pn···PnX3 (Pn = N-Bi; X = F-I), dithallenes RTlTlR (R = H, Me, tBu, Ph) and octachalcogen dications Ch82+ (Ch = S, …

atomitkemialliset sidoksetstable radicalssynthesisintermolecular interactionskemiatheoretical and computational chemistrysinglet diradical characterintramolecular interactionsmolekyylitsynteesimain group chemistryclosed shell interactions
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Type 1 Diabetes and Autoimmune Thyroid Disease—The Genetic Link

2021

Type 1 diabetes (T1D) and autoimmune thyroid disease (AITD) are the most frequent chronic autoimmune diseases worldwide. Several autoimmune endocrine and non-endocrine disorders tend to occur together. T1D and AITD often cluster in individuals and families, seen in the formation of autoimmune polyendocrinopathy (AP). The close relationship between these two diseases is largely explained by sharing a common genetic background. The HLA antigens DQ2 (DQA1*0501-DQB1*0201) and DQ8 (DQA1*0301-DQB1*0302), tightly linked with DR3 and DR4, are the major common genetic predisposition. Moreover, functional single nucleotide polymorphisms (or rare variants) of various genes, such as the cytotoxic T-lym…

autoimmune polyendocrinopathyendocrine system diseasestype 1 diabetesEndocrinology Diabetes and MetabolismSingle-nucleotide polymorphismGenome-wide association studyCLEC16AHuman leukocyte antigenReviewBiologyPolymorphism Single Nucleotidelcsh:Diseases of the endocrine glands. Clinical endocrinologyPTPN22single nucleotide polymorphismsEndocrinologyimmune system diseasesGenetic predispositionHumansGenetic Predisposition to Diseasesusceptibility genesHLA antigensgenetic linkGeneticslcsh:RC648-665Thyroiditis AutoimmuneFOXP3nutritional and metabolic diseasesAutoimmune polyendocrinopathyDiabetes Mellitus Type 1autoimmune thyroid diseaseFrontiers in Endocrinology
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Single-trial-based temporal principal component analysis on extracting event-related potentials of interest for an individual subject.

2023

Background: Temporal principal component analysis (tPCA) has been widely used to extract event-related potentials (ERPs) at group level of multiple subjects ERP data and it assumes that the underlying factor loading is fixed across participants. However, such assumption may fail to work if latency and phase for one ERP vary considerably across participants. Furthermore, effect of number of trials on tPCA decomposition has not been systematically examined as well, especially for within-subject PCA. New method: We reanalyzed a real ERP data of an emotional experiment using tPCA to extract N2 and P2 from single-trial EEG of an individual. We also explored influence of the number of trials (con…

back-projectionsingle-trial analysisindividual subjectprincipal component analysisGeneral Neuroscienceevent-related potentialsJournal of neuroscience methods
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Comparison between simulated and observed LHC beam backgrounds in the ATLAS experiment at E beam =4 TeV

2018

Results of dedicated Monte Carlo simulations of beam-induced background (BIB) in the ATLAS experiment at the Large Hadron Collider (LHC) are presented and compared with data recorded in 2012. During normal physics operation this background arises mainly from scattering of the 4 TeV protons on residual gas in the beam pipe. Methods of reconstructing the BIB signals in the ATLAS detector, developed and implemented in the simulation chain based on the FLUKA Monte Carlo simulation package, are described. The interaction rates are determined from the residual gas pressure distribution in the LHC ring in order to set an absolute scale on the predicted rates of BIB so that they can be compared qua…

background [beam]background: inducedPhysics::Instrumentation and DetectorsCiencias FísicasMonte Carlo method01 natural sciencesHigh Energy Physics - ExperimentSubatomär fysik//purl.org/becyt/ford/1 [https]High Energy Physics - Experiment (hep-ex)beam lossesSubatomic Physicsscattering [p p][PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]and programsInstrumentationQCMathematical PhysicsPhysicsLarge Hadron ColliderRadiation calculationsAtlas (topology)Accelerator modelling and simulations (multi-particle dynamics; single-particle dynamics)DetectorATLAS experimentSettore FIS/01 - Fisica SperimentaleSimulation methods and programBeams (radiation) Accelerator modelling and simulations (multi-particle dynamics;; single-particle dynamics); Radiation calculations; Simulation methods; and programs; DETECTOR; SEARCHObservableAccelerator modelling and simulations (multi-particle dynamicMonte Carlo [numerical calculations]ATLASNuclear & Particles PhysicsAccelerator modelling and simulationsCERN LHC Coll collimators beam: backgroundcolliding beams [p p]numerical calculations: Monte CarloCIENCIAS NATURALES Y EXACTASParticle Physics - Experimentp p: scatteringAccelerator modelling and simulations (multi-particle dynamics; Radiation calculations; Simulation methods and programs; single-particle dynamics); Instrumentation; Mathematical Physics530 PhysicsCiências Naturais::Ciências Físicas:Ciências Físicas [Ciências Naturais]FOS: Physical sciencesFísica de Partículas y CamposAccelerator Physics and InstrumentationNuclear physicsFLUKAsingle-particle dynamics)ATLAS LHC High Energy PhysicsHIGH ENERGY PHYSICSSEARCH0103 physical sciencesddc:610010306 general physicsAbsolute scaleDETECTORpressure [gas]Science & Technology010308 nuclear & particles physicsScatteringhep-exRadiation calculationscatteringAcceleratorfysik och instrumentering//purl.org/becyt/ford/1.3 [https]ghostAccelerator modelling and simulations (multi-particle dynamicsSimulation methodscorrelationinduced [background]Experimental High Energy Physicsgas: pressureSimulation methods and programsp p: colliding beamsexperimental results
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Introducing evidence-based practices to manage problem behaviours at school: The behave application

2020

In the last years, an increasing awareness amongst educator and scholastic psychologists of the relevance to manage behavioural and emotional problems applying evidence-based approaches, and quasi-experimental designs is emerging. This request, however, must come to terms with certain barriers that persist in the school environment. The introduction of quantified methods to assess and monitor student's results, to evaluate the efficacy of the intervention, to understand the evolution of the single, is not part of the usual teacher's curriculum. The present paper describes the BEHAVE (Behavioral management model across Europe) application, a tool able to support the transition of all educato…

behavioural interventionICTSingle case experimental designProblem behavioursapplicationEducationEvidence-based
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Connections Between Single-Level and Bilevel Multiobjective Optimization

2011

The relationship between bilevel optimization and multiobjective optimization has been studied by several authors and there have been repeated attempts to establish a link between the two. We unify the results from the literature and generalize them for bilevel multiobjective optimization. We formulate sufficient conditions for an arbitrary binary relation to guarantee equality between the efficient set produced by the relation and the set of optimal solutions to a bilevel problem. In addition, we present specially structured bilevel multiobjective optimization problems motivated by real-life applications and an accompanying binary relation permitting their reduction to single-level multiob…

bilevel optimizationMathematical optimizationMatematikControl and OptimizationRelation (database)Multiobjective programmingBinary relationTwo-level optimizationApplied MathematicsMulticriteriaManagement Science and Operations ResearchSingle levelmonitavoiteoptimointiMulti-objective optimizationBilevel optimizationSet (abstract data type)Reduction (complexity)Theory of computationmultiobjective optimizationMathematicsMathematics
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Performance under Pressure on the Court: Evidence from Professional Volleyball

2018

This study analyzes how psychological pressure affects performance. It refers to the discussion on differences between choking, i.e., an acute performance decline under pressure and under- performance under pressure. When performance outcomes are not defined binary even slight performance decrements can have huge consequences for future career. To study the conse- quences of psychological pressure on performance, we employ data on the serving performance of 213 professional volleyball athletes in 226 matches. We do not find any evidence for the existence of severe performance decrements under pressure (i.e. choking). However, athletes serve less effectively under pressure, i.e., they serve …

biologyAthletesAcute failureSingle groupFuture careermedicine.diseasebiology.organism_classificationGroup cohesivenessmedicinePsychological pressureTeam productionChokingPsychologySocial psychologySSRN Electronic Journal
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