Search results for "Sleep Apnea"

showing 10 items of 257 documents

Lipid peroxidation and nitric oxide metabolites in a group of subjects with obstructive sleep apnea syndrome.

2015

It is known that in OSAS the plasma lipid peroxidation has an opposite behavior in comparison with nitric oxide metabolites. In the re-examination of our survey of OSAS subjects we calculated the ratio between thiobarbituric acid reactive substances (TBARS) and nitric oxide metabolites (NOx) in relation to OSAS severity. The study has regarded 48 OSAS subjects subdivided in two subgroups according to the apnea/hypopnea index - AHI- (Low = 21 subjects with AHI30 and High = 27 subjects with AHI30). From the obtained data it is evident that the TBARS/NOx ratio is significantly higher in the H subgroup compared to L subgroup as well as this ratio is reduced in L subgroup in comparison with the …

Malemedicine.medical_specialtyPhysiologyThiobarbituric acidobstructive sleep apnea syndrome030204 cardiovascular system & hematologyNitric OxideNitric oxideLipid peroxidation03 medical and health scienceschemistry.chemical_compound0302 clinical medicinestomatognathic systemnitric oxide metabolitePhysiology (medical)Internal medicineTBARSLipid peroxidation; nitric oxide metabolites; obstructive sleep apnea syndrome; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Nitric Oxide; Sleep Apnea Obstructive; Physiology; Hematology; Cardiology and Cardiovascular Medicine; Physiology (medical)MedicineHumansNOxSleep Apnea Obstructivebusiness.industryApneaHematologyMiddle Agedmedicine.diseasenervous system diseasesrespiratory tract diseasesObstructive sleep apneaEndocrinology030228 respiratory systemchemistryFemaleLipid Peroxidationmedicine.symptomCardiology and Cardiovascular MedicinebusinessHypopneaHumanClinical hemorheology and microcirculation
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Metabolic Syndrome and Vitamin D Levels in Patients with Obstructive Sleep Apnea Syndrome

2018

Numerous studies have indicated that obstructive sleep apnea syndrome (OSAS), may contribute to the development of metabolic syndrome (MetS) and diabetes. Moreover, OSAS has been associated with lowered vitamin D (Vit D) levels, but reports are inconclusive. Aim of the study was to compare Vit D levels according to the presence of MetS and its components in OSAS patients.The presence of MetS was evaluated and serum 25-hydroxy vitamin D [25(OH)D] levels were measured in consecutive newly diagnosed, by polysomnography, subjects with OSAS.A total of 107 subjects (88 men) with OSAS were included in the study. Patients were divided into group A (OSAS with MetS group: 55 subjects) and group B (OS…

Malemedicine.medical_specialtyPolysomnographyEndocrinology Diabetes and MetabolismBlood Pressure030209 endocrinology & metabolismPolysomnographySeverity of Illness IndexGastroenterologyGroup BBody Mass Index03 medical and health sciences0302 clinical medicineDiabetes mellitusInternal medicineInternal MedicineVitamin D and neurologyHumansMedicineVitamin DAgedMetabolic SyndromeSleep Apnea ObstructiveAnthropometrymedicine.diagnostic_testbusiness.industryEpworth Sleepiness ScaleVitaminsMiddle AgedVitamin D Deficiencymedicine.diseasenervous system diseasesrespiratory tract diseasesObstructive sleep apneaFemaleMetabolic syndromebusinessBody mass index030217 neurology & neurosurgeryMetabolic Syndrome and Related Disorders
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A survey around the Italian pediatric units on current clinical practice for Sleep Disordered Breathing (SDB)

2019

Background During recent years, interest on Sleep Disordered Breathing (SDB) in pediatric age has increased, due to the impact on quality of life, psycho-physical attitude and other serious morbidities if undiagnosed and untreated. Methods Italian Pediatric Respiratory Diseases Society (SIMRI) SDB-Working Group carried out an exploratory survey in Italy, from January to December 2016, to assess the diagnostic and therapeutic pathways, perception and relevance of SDB in Italian Hospitals. Results A questionnaire was sent to 180 Pediatric Units (PUs) distributed throughout the Italy; 102 Pediatric Units (PUs; 56.6%) answered and among them 57% dealt with SDB, and 94% recognized SDB as a major…

Malemedicine.medical_specialtyPractice PatternsPolysomnographyChildren; Italy; Pediatric units; Sleep disordered breathing; Survey; Child; Female; Humans; Italy; Male; Practice Patterns Physicians'; Sleep Apnea Syndromes; Surveys and QuestionnairesChildren; Italy; Pediatric units; Sleep disordered breathing; Survey03 medical and health sciencesExploratory surveySleep Apnea Syndromes0302 clinical medicineQuality of lifeSurveys and Questionnaires030225 pediatricsmental disordersmedicineHumanscardiovascular diseases030212 general & internal medicinePractice Patterns Physicians'ChildPediatric unitsSurveyChildrenPhysicians'medicine.diagnostic_testSleep disordered breathingPediatric respiratory diseasesbusiness.industryResearchlcsh:RJ1-570lcsh:PediatricsPediatric agenervous system diseasesrespiratory tract diseasesNorthern italyClinical PracticeItalyEmergency medicineSleep disordered breathingFemalebusinessItalian Journal of Pediatrics
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Efficacy of mandibular advancement device in the treatment of obstructive sleep apnea syndrome: A randomized controlled crossover clinical trial

2015

Background Evaluation of the efficacy and safety of a mandibular advancement device (MAD) (KlearwayTM) in the treatment of mild-to-moderate obstructive sleep apnea and chronic roncopathy. Material and Methods A randomized, placebo-controlled, double blinded, and crossover clinical trial was conducted. Placebo device (PD) defined as a splint in the centric occlusion that did not induce a mandibular advancement served as a control. The mandible was advanced to the maximum tolerable distance or to a minimum of 65% of the maximum protrusion. After each sequence of treatment, patients were assessed by questionnaires, conventional polysomnography, and objective measurement of snoring at the patie…

Malemedicine.medical_specialtyanimal structuresOdontologíaPolysomnographyPlaceboSeverity of Illness Indexlaw.inventionRandomized controlled trialstomatognathic systemDouble-Blind MethodlawSeverity of illnessmedicineHumansGeneral DentistrySleep Apnea ObstructiveCross-Over Studiesmedicine.diagnostic_testbusiness.industryResearchSleep apneaMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in DentistryCrossover studyCiencias de la saludSurgeryrespiratory tract diseasesClinical trialObstructive sleep apneaTreatment OutcomeOtorhinolaryngologyAnesthesiaUNESCO::CIENCIAS MÉDICASSurgeryFemalebusinessMandibular AdvancementMedicina Oral, Patología Oral y Cirugía Bucal
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Obstructive sleep apnoea independently predicts lipid levels: Data from the European Sleep Apnea Database

2018

Background and objective: Obstructive sleep apnoea (OSA) and dyslipidaemia are independent risk factors for cardiovascular disease. This study investigates the association between OSA and plasma lipid concentrations in patients enrolled in the European Sleep Apnea Database (ESADA) cohort. Methods: The cross-sectional analysis included 8592 patients without physician-diagnosed hyperlipidaemia or reported intake of a lipid-lowering drug (age 50.1 ± 12.7 years, 69.1% male, BMI: 30.8 ± 6.6 kg/m2, mean apnoea–hypopnoea index (AHI): 25.7 ± 25.9 events/h). The independent relationship between measures of OSA (AHI, oxygen desaturation index (ODI), mean and lowest oxygen saturation) and lipid profil…

MaleobesityDatabases Factualcholesterol dyslipidemia hypoxia obesity sleep apnoeaGastroenterologyCohort Studieschemistry.chemical_compound0302 clinical medicineRisk FactorsHypolipidemic AgentsOxygen saturation (medicine)Sleep Apnea Obstructivemedicine.diagnostic_testSleep apneaMiddle AgedEuropeQuartileCardiovascular DiseasesCohortFemalelipids (amino acids peptides and proteins)AdultPulmonary and Respiratory Medicinemedicine.medical_specialtySettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesInternal medicinemedicineHumansTriglyceridesDyslipidemiashypoxiaCholesterolbusiness.industryCholesterol HDLdyslipidemiacholesterolCholesterol LDLta3121medicine.diseaseObesitynervous system diseasesrespiratory tract diseasesCross-Sectional Studies030228 respiratory systemchemistryLipid profilebusinesssleep apnoea030217 neurology & neurosurgeryDyslipidemiaRespirology
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Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study

2019

[No abstract available]

MaleobesityLetterDatabases FactualDownload[SDV]Life Sciences [q-bio]cigarette smokingPolysomnographycancer riskdisease burdenapnea hypopnea indexsleep disordered breathingstudy design0302 clinical medicinepolysomnographyRisk FactorsNothingcancer diagnosisNeoplasmsmiddle agedgenderPrevalence030212 general & internal medicineSleep studyobstructive sleep apneaSleep Apnea Obstructiveeducation.field_of_studyanthropometryquantitative analysismedicine.diagnostic_testadultrisk assessmentclinical trialcohort analysisprostate cancerpulse oximetry[SDV] Life Sciences [q-bio]Europenot availablecomorbidityagedfemalewaist hip ratiocolon cancerpriority journalrisk factorfactual databasedisease severitycerebrovascular accidentPulmonary and Respiratory Medicinemedicine.medical_specialtyalcohol consumptionintermittent hypoxiaPopulationMEDLINElymphomaSettore MED/10 - Malattie Dell'Apparato Respiratoriomalignant neoplasmcancer growth03 medical and health sciencesmelanomamedicinecancercross-sectional studyHumanscontrolled studyhumaneducationCancer prevalencehypoxiabusiness.industrystatistical modelConflict of interestpredictionmajor clinical studybody massoxygen saturationlung cancermulticenter studyCross-Sectional StudiesLogistic Modelsage030228 respiratory systemdisease severity assessmentFamily medicineoxygen desaturation indexhead and neck cancerHuman medicinebusinessneoplasmEuropean Respiratory Journal
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Effects of mandibular setback surgery on upper airway dimensions and their influence on obstructive sleep apnoea - a systematic review.

2015

Abstract Background Mandibular setback used to be the traditional treatment of choice for correcting mandibular prognathism. Nowadays, bimaxillary surgery is preferred. Several authors have asserted that mandibular setback causes a relative narrowing of the upper airway (UA) that could trigger obstructive sleep apnoea (OSA); however, its potential role in OSA development is still much debated. Another controversial subject is whether changes in airway space caused by the procedure are permanent. Objectives To ascertain the consequences for UA size and shape of mandibular setback surgery in comparison with bimaxillary surgery (maxillary advancement with Le Fort I and mandibular setback), and…

Mandibular setback surgerymedicine.medical_treatmentOrthognathic surgeryMEDLINEMandibular OsteotomyDentistryOropharynxstomatognathic systemNasopharynxmedicineMaxillaHumansOsteotomy Le FortOximetryOrthodonticsSleep Apnea Obstructivebusiness.industryClinical trialHypopharynxSystematic reviewMandibular prognathismOtorhinolaryngologyCohortPharynxSurgeryOral SurgerybusinessAirwayJournal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
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Perioperative Adverse Events in Obstructive Sleep Apnea and Use of Noninvasive Mechanical Ventilation: Key Topics and Clinical Implications

2016

Obstructive sleep apnea (OSA) is a common public health care problem and, yet, the perioperative management of OSA remains inadequate. Patients affected by this condition are prone to early postoperative complications, in part due to the negative effects of sedative, analgesic, and anesthetic agents on pharyngeal tone and arousal responses to hypoxia, hypercapnia, and obstruction. The use of opioids may also contribute to late adverse events, mainly by suppressing the rapid eye movement phase of sleep. As a result, preoperative screening of patients at high risk of OSA, as well as the implementation of a perioperative strategy to reduce the risk of complications, should lead to early periop…

Mechanical ventilationmedicine.medical_specialtymedicine.drug_classbusiness.industrymedicine.medical_treatmentPerioperativeHypoxia (medical)medicine.diseaserespiratory tract diseasesObstructive sleep apneaSedativeObstructive sleep apnea Perioperative complications Noninvasive ventilation Noninvasive positive pressure ventilation Continuous positive airway pressuremedicineContinuous positive airway pressuremedicine.symptomIntensive care medicineAdverse effectbusinessHypercapnia
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The Role of Modified Expansion Sphincter Pharyngoplasty in Multilevel Obstructive Sleep Apnea Syndrome Surgery

2017

Introduction Obstructive sleep apnea syndrome (OSAS) is a sleep disorder caused by an excessive narrowing of the pharyngeal airway that also collapses during inspiration, with an important role played by the lateral pharyngeal wall in the development of the obstruction. Objective To describe our surgical experience with modified expansion sphincter pharyngoplasty (MESP) in the management of lateral collapse in upper airway multilevel surgery. Methods A total of 20 patients with moderate to severe OSAS were recruited in the Ear, Nose and Throat (ENT) Department of the University of Palermo, Italy. All of the enrolled patients refused the ventilatory therapy. The subjects were evaluated for …

Müller's maneuvermedicine.medical_specialtymedicine.medical_treatmentlcsh:Medicineobstructive sleep apnea syndromenasopharyngeal disease03 medical and health sciences0302 clinical medicinemedicinesleep apnea syndromesnasopharyngeal diseasessleep apnea syndrome030223 otorhinolaryngologyNoseOriginal ResearchSleep disordersoft palateobstructive sleep apnea hypopnea syndromeSoft palatebusiness.industryOtorhinolaryngology2734 Pathology and Forensic Medicinesleep-disordered breathinglcsh:RSleep apnea030206 dentistrymedicine.diseaselcsh:Otorhinolaryngologylcsh:RF1-547Surgeryrespiratory tract diseasesObstructive sleep apneamedicine.anatomical_structureOtorhinolaryngologySphincterAirwaybusinessInternational Archives of Otorhinolaryngology
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Fusion of the

2015

Chronic obstructive pulmonary disease, COPD, affects the condition of the entire human organism and causes multiple comorbidities. Pathological lung changes lead to quantitative changes in the composition of the metabolites in different body fluids. The obstructive sleep apnea syndrome, OSAS, occurs in conjunction with chronic obstructive pulmonary disease in about 10–20 % of individuals who have COPD. Both conditions share the same comorbidities and this makes differentiating them difficult. The aim of this study was to investigate whether it is possible to diagnose a patient with either COPD or the OSA syndrome using a set of selected metabolites and to determine whether the metabolites t…

NMR spectroscopyOriginal ArticleChronic obstructive pulmonary disease (COPD)ChemometricsObstructive sleep apnea syndrome (OSAS)Discriminant modelsrespiratory tract diseasesMetabolomics : Official journal of the Metabolomic Society
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