Search results for "Sleep"

4-Aminopyridine (4AP) Enhances Acetylcholine Output from the Rat Cerebral Cortex in vivo

1982

Publisher Summary This chapter discusses a study to analyze the effect of 4-aminopyridine (4AP) administration on cortical acetylcholine (ACh) output. The study was done on adult male Wistar rats under urethane or pentobarbital anesthesia. A small Perspex cylinder filled with eserinized Ringer solution was applied on the exposed cerebral cortex. The solution in the collecting cylinder was removed every 10 min and its ACh content was determined by bioassay on the dorsal muscle of the leech. In urethane anaesthetized rats, the control ACh output was 0.98 ± 0.16 ng/min/cm2 and the administration of 4AP (3 mg/kg i.p.) was followed by a rapid increase in ACh output lasting at least 40 min. The i…

Eroded enamel rehardening using two intraoral appliances designs in different times of salivary exposure.

2019

Background The aim of this study was evaluated the eroded enamel rehardening potential using upper palatal and lower buccal removable appliances in different times of salivary exposure (30 min, 1h, 2h, 12h) after a single erosive challenge event. Material and Methods After initial surface hardness evaluation, bovine enamel blocks were eroded in vitro (0.01 M hydrochloric acid, pH 2.3, 30 seconds), selected (n = 160) and randomly assigned to the two appliance designs and twenty volunteers. Four enamel blocks were inserted in each removable appliance. On the in situ phase, the volunteers were instructed to use the upper palatal and lower buccal appliances simultaneously for 12 nonconsecutive …

Uvulopalatopharyngoplasty with tonsillectomy in the treatment of severe OSAS

2009

Objective: To establish the efficacy of uvulopalatopharyngoplasty with tonsillectomy for treating selected patients with severe obstructive sleep apnea syndrome Methodology: Retrospective study of patients who underwent clinical/instrumental evaluation and surgical treatment. Setting: University ENT division with a tertiary snoring referral center Participants: Twenty-two patients with normal body mass index affected by severe obstructive sleep apnea syndrome- Main outcome measures: Pre and post operative cardiopulmonary monitoring during sleep, daytime sleepiness evaluation, post treatment complication recording. Results: Complete response to therapy was obtained in 78% of patients. Four p…

Position paper on the management of patients with obstructive sleep apnea and hypertension: joint recommendations by the European Society of Hyperten…

2012

This article is aimed at addressing the current state of the art in epidemiology, pathophysiology, diagnostic procedures and treatment options for appropriate management of obstructive sleep apnea (OSA) in cardiovascular (particularly hypertensive) patients, as well as for the management of cardiovascular diseases (particularly arterial hypertension) in OSA patients. The present document is the result of the work done by a panel of experts participating in the European Union COST (COoperation in Scientific and Technological research) ACTION B26 on OSA, with the endorsement of the European Respiratory Society (ERS) and the European Society of Hypertension (ESH). These recommendations are par…

Testing the direct and moderator effects of the stressor-detachment model over one year : A latent change perspective

2018

ABSTRACTTo test the direct and moderator effects of the stressor–detachment model from a long-term perspective, we investigated whether workload and detachment are related to changes in exhaustion and sleep difficulties over one year. We also examined whether detachment attenuates the relationship between high workload and these outcomes both cross-sectionally and over time. Questionnaire data with 1722 respondents at Time 1 and 1182 respondents at Time 2 were collected. We used a latent change score approach to analyse the data in order to identify intra-individual change among the studied constructs. Our results showed that high workload and low detachment at baseline were related to an i…

Spanish Version Of The Quebec Sleep Questionnaire (QSQ)

2010

Improved SOM Learning using Simulated Annealing

2007

Self-Organizing Map (SOM) algorithm has been extensively used for analysis and classification problems. For this kind of problems, datasets become more and more large and it is necessary to speed up the SOM learning. In this paper we present an application of the Simulated Annealing (SA) procedure to the SOM learning algorithm. The goal of the algorithm is to obtain fast learning and better performance in terms of matching of input data and regularity of the obtained map. An advantage of the proposed technique is that it preserves the simplicity of the basic algorithm. Several tests, carried out on different large datasets, demonstrate the effectiveness of the proposed algorithm in comparis…

Estimating the decomposition of predictive information in multivariate systems

2015

In the study of complex systems from observed multivariate time series, insight into the evolution of one system may be under investigation, which can be explained by the information storage of the system and the information transfer from other interacting systems. We present a framework for the model-free estimation of information storage and information transfer computed as the terms composing the predictive information about the target of a multivariate dynamical process. The approach tackles the curse of dimensionality employing a nonuniform embedding scheme that selects progressively, among the past components of the multivariate process, only those that contribute most, in terms of co…

Cognitive Deficits in Chronic Stroke Patients: Neuropsychological Assessment, Depression, and Self-Reports

2017

<b><i>Background:</i></b> Following stroke, clinicians are challenged to detect and untangle symptoms of cognitive dysfunction and mood disorders. Additionally, they need to evaluate the informative value of self-reports to identify patients in need of further attendance. <b><i>Aims:</i></b> To examine the association between neuropsychological measures, symptoms of depression, and self-reported cognitive function. <b><i>Methods:</i></b> One-hundred and five chronic stroke patients underwent assessment covering 6 cognitive domains and answered the Hospital Anxiety and Depression Scale and the Memory and Thinking Scale f…

Boosting working memory with accelerated clocks

2021

Our perception of time varies with the degree of cognitive engagement in tasks. The perceived passage of time accelerates while working on demanding tasks, whereas time appears to drag during boring situations. Our experiment aimed at investigating whether this relationship is mutual: Can manipulated announcements of elapsed time systematically affect the attentional resources applied to a cognitive task? We measured behavioral performance and the EEG in a whole report working memory paradigm with six items of different colors that each had to be reported after a short delay period. The 32 participants were informed about the current time after each 20 trials, while the clock was running at…