Search results for "Small"

showing 10 items of 2441 documents

Correlation between fecal calprotectin and inflammation in the surgical specimen of Crohn's disease

2016

Background: An accurate assessment of the inflammatory activity is crucial to establish the most appropriate treatment in Crohn's disease (CD). The present study aimed to evaluate the utility of preoperative fecal calprotectin (FC) measurement in small bowel CD and its relationship with inflammatory activity in surgical pathology specimens. Methods: This was a prospective observational study including all the patients with small bowel CD operated on at our center between March 2011 and September 2013. Preoperative laboratory and stool tests were performed. A meticulous exploration of entire small bowel was performed during surgery, and the resected bowel (or a sample of whole intestinal wal…

AdultMalemedicine.medical_specialtyPathologymedicine.medical_treatmentInflammationGastroenterologySensitivity and SpecificitySeverity of Illness IndexSurgical pathology03 medical and health sciencesFeces0302 clinical medicineFecal calprotectinCrohn DiseaseInternal medicineIntestine SmallmedicineStrictureplastyHumansProspective StudiesSurgical pathologyProspective cohort studyAgedAged 80 and overCrohn's diseaseLeukocyte L1 Antigen Complexbusiness.industryBiomarkerMiddle Agedmedicine.diseaseSmall bowel Crohn's disease030220 oncology & carcinogenesisPreoperative PeriodBiomarker (medicine)030211 gastroenterology & hepatologySurgeryFemalemedicine.symptomCalprotectinbusinessLeukocyte L1 Antigen ComplexBiomarkers
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Early clinical outcomes after small incision lenticule extraction surgery (SMILE)

2018

Abstract Purpose Dry eye is known to impact on clinical outcomes after laser vision correction and the use of a newer ‘all femtosecond laser’ surgical approach may be associated with less impact on the ocular surface post-operatively. The purpose of this study was to evaluate the early clinical outcomes and tear instability after the first small incision lenticule extraction (SMILE) cases undertaken by three surgeons at a single site in the UK. Methods Retrospective audit. Seventy-one eyes of 37 patients underwent SMILE surgery using the Zeiss VisuMax laser system (Carl Zeiss Meditec, Germany). Uncorrected and corrected distance visual acuity, spherical equivalent refraction, fluorescein en…

AdultMalemedicine.medical_specialtyVisual acuityDistance visual acuitygenetic structuresCorneal Surgery LaserCorneal StromaVisual AcuityRefraction Ocularlaw.invention03 medical and health sciences0302 clinical medicineSingle sitelawOphthalmologyMyopiamedicineHumansSmall incision lenticule extractionSmile surgeryRetrospective StudiesSurgical approachKeratometerbusiness.industryCorneal TopographyGeneral Medicineeye diseasesSurgeryOphthalmologyTears030221 ophthalmology & optometryFemaleLasers Excimersense organsmedicine.symptombusinessOcular surface030217 neurology & neurosurgeryOptometry
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Combined effects of increasing maternal age and nulliparity on hypertensive disorders of pregnancy and small for gestational age

2019

The mean age of women delivering for the first time is increasing, and this combination could lead to an increased risk of perinatal complications.The objective was to evaluate the potential combined effects of nulliparity and increasing maternal age on small for gestational age (SGA  10th percentile) and hypertensive disorders of pregnancy (HDP).A population-based cohort study was conducted using data routinely collected on all births in 11 hospitals in the Burgundy perinatal network between 2007 and 2016. Pregnant women with singleton deliveries aged 20 years or older were included at delivery and divided into groups according to maternal age (20 to 24-year-old group as a reference). Mult…

AdultMalemedicine.medical_specialty[SDV]Life Sciences [q-bio]PopulationLogistic regressionCohort StudiesYoung Adult03 medical and health sciences0302 clinical medicinePregnancyRisk FactorsInternal MedicinemedicineHumans030212 general & internal medicineRisk factoreducation2. Zero hungereducation.field_of_studyPregnancy030219 obstetrics & reproductive medicinebusiness.industryObstetricsAge FactorsInfant NewbornObstetrics and GynecologyHypertension Pregnancy-InducedMiddle Agedmedicine.disease3. Good health[SDV] Life Sciences [q-bio]ParityLogistic ModelsInfant Small for Gestational AgeSmall for gestational ageFemaleFrancebusinessParity (mathematics)Body mass indexMaternal AgeCohort studyPregnancy Hypertension
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Forty-slice MDCT enteroclysis: evaluation after oral administration of isotonic solution in Crohn's disease.

2007

Objective. The aim of this study was to evaluate the accuracy of multidetector computed tomography (MDCT) enteroclysis after oral hyperhydration with isotonic solution in detecting bowel wall alterations in patients with Crohn’s disease. Materials and methods. Twenty-eight patients with a diagnosis of Crohn’s disease established by ileocolonoscopy and histology were enrolled in the study; 15 patients with negative ileocolonoscopy served as controls. In all cases, MDCT enteroclysis was performed after oral administration of 2,000 ml of isotonic solution and intravenous administration of N-butylscopolamine. Axial, isotropic multiplanar and volume-rendered reconstructions were used to evaluate…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentAdministration OralContrast MediaIntestino tenueSensitivity and SpecificityPolyethylene GlycolsCrohn DiseaseOral administrationPatologie gastrointestinaliIntestine SmallMedicineIntubationHumansRadiology Nuclear Medicine and imagingNeuroradiologyTC multidetettoreCrohn's diseasemedicine.diagnostic_testbusiness.industryCatharticsMultidetector CTUltrasoundInterventional radiologyGeneral MedicineEnemamedicine.diseaseGastrointestinal diseaseSmall boweldigestive system diseasesSpiral computed tomographyIopamidolFemaleRadiologyIsotonic SolutionsbusinessTomography X-Ray ComputedLa Radiologia medica
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Crohn's disease: A comparative prospective study of transabdominal ultrasonography, small intestine contrast ultrasonography, and small bowel enema

2005

Background: Small intestine contrast ultrasonography (SICUS), when performed after distention of the small bowel lumen with an iso-osmolar polyethylene glycol electrolyte-balanced solution, shows high sensitivity (100%) and specificity (97%) in detecting small bowel abnormalities in patients who have not received a diagnosis but in whom there is a suspicion of intestinal diseases. The diagnostic yield of SICUS remains to be established in detecting small bowel lesions in patients with proven Crohn's disease (CD) in comparison with transabdominal ultrasonography (TUS), and in relationship to the experience of the operator, using small bowel enema (SBE) as the “gold standard.” Aim: The aim of…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentContrast MediaSmall bowel enemaLumen (anatomy)EnemaSensitivity and SpecificityGastroenterologyPolyethylene GlycolsDiagnosis DifferentialJejunumSettore MED/12Professional CompetenceCrohn DiseaseInternal medicineAbdomenIntestine SmallmedicineHumansImmunology and AllergyProspective cohort studyUltrasonographyCrohn's diseaseSicusbiologybusiness.industryGastroenterologyEnemaMiddle AgedSmall bowelmedicine.diseasebiology.organism_classificationSmall intestineCrohn's diseaseStenosismedicine.anatomical_structureSolventsFemalebusinessDilatation Pathologic
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Liver "Compliance": A previously unrecognized preoperative predictor of small-for-size syndrome in adult living donor liver transplantation

2008

The purpose of this study was to investigate the effect of liver compliance on computed tomography (CT) volumetry and to determine its association with postoperative small-for-size syndrome (SFSS).Unenhanced, arterial, and venous phase CT images of 83 consecutive living liver donors who underwent graft hepatectomy for adult-to-adult living donor liver transplantation (ALDLT) were prospectively subjected to three-dimensional (3-D) CT liver volume calculations and virtual 3-D liver partitioning. Graft volume estimates based on 3-D volumetry, which subtracted intrahepatic vascular volume from the "smallest" (native) unenhanced and the "largest" (venous) CT phases, were subsequently compared wi…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentLiver transplantationHepatic VeinsliverLiver massLiver ctUser-Computer InterfacemedicineLiving DonorsHumansSurvivorsRetrospective StudiesTransplantationSmall for size syndromebusiness.industryMortality rateBody WeightOrgan SizeMiddle AgedSurvival AnalysisLiver TransplantationCompliance (physiology)Tissue and Organ HarvestingSurgeryFemaleRadiologyHepatectomyLiving donor liver transplantationbusinessTomography X-Ray Computed
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An extended theory of planned behavior for parent-for-child health behaviors: A meta-analysis

2020

OBJECTIVE: To conduct a meta-analysis of studies examining the determinants of behaviors performed by parents to promote the health of their child, termed "parent-for-child health behaviors," based on an extended theory of planned behavior. Specifically, the study aimed to meta-analyze correlations among theory of planned behavior constructs, planning, and past behavior, and use them to test theory predictions and effects of salient moderators. METHOD: A systematic search identified 46 studies that provided correlations between at least one theory construct and intention or behavior for parent-for-child behaviors. Theory predictions were tested using meta-analytic structural equation modeli…

AdultMaleterveyspsykologiaHealth BehaviorPsycINFOStructural equation modelingDevelopmental psychologyvanhempi-lapsisuhde03 medical and health scienceskäyttäytymismallitSocial cognitionHumansParent-Child RelationsChildQualitative ResearchApplied Psychology030505 public healthmeta-analyysisosiaalinen kognitioInfant NewbornTheory of planned behaviorInfantMiddle AgedTest theoryModerationPsychiatry and Mental healthHealth promotionChild PreschoolterveyskäyttäytyminenFemale0305 other medical scienceConstruct (philosophy)Psychology
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Oral versus intravenous vinorelbine: clinical safety profile

2005

The availability of chemotherapeutic drugs administrable by oral route represents a step forward in the management of cancer patients. Among oral agents, vinorelbine is particularly interesting for its pharmacological characteristics and clinical efficacy. Oral vinorelbine is rapidly absorbed (1.5-3 hours) with an elimination half-life of approximately 40 hours. It shows a low level of binding to plasma proteins (13%), is highly bound to platelets (78%) and has a hepatic metabolism and an absolute bioavailability of 40% with a moderate and similar interpatient variability for the two forms. Food has no influence on the pharmacokinetic profile of oral vinorelbine even if nausea/vomiting is l…

AdultNauseaAdministration OralBiological AvailabilityPharmacologyVinblastineVinorelbineAbsorptionEatingTherapeutic indexCytochrome P-450 Enzyme SystemPharmacokineticsOral administrationNeoplasmsmedicineHumansPharmacology (medical)Infusions IntravenousAgedbreast cancer non-small cell lung cancer (NSCLC) oral vinorelbinebusiness.industryStandard treatmentAge FactorsVinorelbineGeneral MedicineMiddle AgedAntineoplastic Agents PhytogenicLiverVomitingmedicine.symptombusinessDrug metabolismHalf-Lifemedicine.drug
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Solid variant of mammary "adenoid cystic carcinoma with basaloid features" merging with "small cell carcinoma"

2005

We describe a rare case of a solid variant of a mammary adenoid cystic carcinoma with basaloid features (sbACC) and its coexistence with a "small cell" carcinoma (SCC), identified and confirmed by histological and immunohistochemical observations: the absence of glandular structures and PAS-positive globules, positivity for neuroendocrine markers (NSE, synaptophysin and chromogranin), and negativity for 34betaE12 and SMA actin were the aspects suggesting the presence of SCC. Furthermore, positivity for CD10 was found both in sbA CC and in SCC, supporting the hypothesis that the two components share the same histogenetic myoepithelial origin and represent an example of dedifferentiation alon…

AdultPathologymedicine.medical_specialtyAdenoid cystic carcinoma2734Breast NeoplasmsBiologyHistogenesisSettore MED/08 - Anatomia PatologicaMastectomy SegmentalSmall-cell carcinomaPathology and Forensic MedicineNeoplasms Multiple PrimaryBiomarkers TumormedicineCarcinomaHumansBreastCarcinoma Small CellneoplasmsSmall cell carcinomaMyoepithelial cellChromogranin ABasaloid adenoid cystic carcinomaCell BiologyPeriodic Acid-Schiff Reactionmedicine.diseaseCarcinoma Adenoid CysticImmunohistochemistrystomatognathic diseasesSettore MED/18 - Chirurgia GeneraleCarcinoma Basal CellChemotherapy AdjuvantAxillaSynaptophysinbiology.proteinLymph Node ExcisionImmunohistochemistryFemaleBasaloid adenoid cystic carcinoma; Breast; Small cell carcinoma; Adult; Axilla; Biomarkers Tumor; Breast Neoplasms; Carcinoma Adenoid Cystic; Carcinoma Basal Cell; Carcinoma Small Cell; Chemotherapy Adjuvant; Female; Humans; Immunohistochemistry; Lymph Node Excision; Mastectomy Segmental; Neoplasms Multiple Primary; Periodic Acid-Schiff Reaction; 2734Breast NeoplasmHuman
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Risk of infection and adverse outcomes among pregnant working women in selected occupational groups: A study in the Danish National Birth Cohort

2010

Abstract Background Exposure to infectious pathogens is a frequent occupational hazard for women who work with patients, children, animals or animal products. The purpose of the present study is to investigate if women working in occupations where exposure to infections agents is common have a high risk of infections and adverse pregnancy outcomes. Methods We used data from the Danish National Birth Cohort, a population-based cohort study and studied the risk of Infection and adverse outcomes in pregnant women working with patients, with children, with food products or with animals. The regression analysis were adjusted for the following covariates: maternal age, parity, history of miscarri…

AdultPediatricsmedicine.medical_specialtyDenmarkHealth PersonnelHealth Toxicology and MutagenesisPopulationCongenital AbnormalitiesMiscarriageCohort Studieslcsh:RC963-969PregnancyRisk FactorsOccupational ExposuremedicineFood IndustryHumansChild CarePregnancy Complications InfectiousChildeducationeducation.field_of_studyPregnancybusiness.industryTeachingResearchlcsh:Public aspects of medicineInfant NewbornPregnancy OutcomeAbsolute risk reductionPublic Health Environmental and Occupational Healthlcsh:RA1-1270medicine.diseaseOccupational DiseasesSick leaveWorkforcelcsh:Industrial medicine. Industrial hygieneSmall for gestational ageFemalePregnant WomenbusinessBody mass indexCohort studyDemographyEnvironmental Health
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