Search results for "Smut"

showing 10 items of 493 documents

Raman signal reveals the rhombohedral crystallographic structure in ultra-thin layers of bismuth thermally evaporated on amorphous substrate

2021

Under the challenge of growing a single bilayer of Bi oriented in the (111) crystallographic direction over amorphous substrates, we have studied different thicknesses of Bi thermally evaporated onto silicon oxide in order to shed light on the dominant atomic structures and their oxidation. We have employed atomic force microscope, X-ray diffraction, and scanning electron microscope approaches to demonstrate that Bi is crystalline and oriented in the (111) direction for thicknesses over 20 nm. Surprisingly, Raman spectroscopy indicates that the rhombohedral structure is preserved even for ultra-thin layers of Bi, down to $\sim 5$ nm. Moreover, the signals also reveal that bismuth films expo…

Materials scienceXRDFOS: Physical scienceschemistry.chemical_element02 engineering and technologySubstrate (electronics)Crystal structure01 natural sciencesBismuthsymbols.namesakeFísica AplicadaMesoscale and Nanoscale Physics (cond-mat.mes-hall)0103 physical sciencesGeneral Materials Science010306 general physicsRamanCondensed Matter - Materials ScienceThin layersCondensed Matter - Mesoscale and Nanoscale PhysicsMechanical EngineeringThermal evaporationMaterials Science (cond-mat.mtrl-sci)Trigonal crystal system021001 nanoscience & nanotechnologyCondensed Matter PhysicsEngineering physicsAmorphous solidchemistryMechanics of MaterialsBisymbolsChristian ministry0210 nano-technologyRaman spectroscopyUltra-thin layer
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Low Temperature, Vacuum-Processed Bismuth Triiodide Solar Cells with Organic Small-Molecule Hole Transport Bilayer

2021

Herein, the preparation of fully vacuum-processed bismuth triiodide solar cells with low annealing temperature is reported. Planar n-i-p devices are prepared using a thin compact SnO2 layer as the electron extraction layer and an electron blocking/hole extraction bilayer consisting of an intrinsic and doped organic hole-transport molecule. Using this configuration, herein, higher fill-factors and overall power conversion efficiencies than with conventional solution-processed hole transport materials are achieved.

Materials sciencebusiness.industryBilayerchemistry.chemical_elementPhotochemistrySmall moleculeBismuthchemistry.chemical_compoundGeneral EnergychemistryPhotovoltaicsEnergiaTriiodidebusinessCèl·lules fotoelèctriques
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¿Por qué la literatura?

2021

In poetry, as well as in a good part of prose works, the rhythm of words is the music that governs reason and emotion. Literature occupies an important place in my creation. In this article I describe the different procedures in which I configure its presence in my music and the main themes in four of my works: Envoi, Como el viento, Maya and Transmutación.

Maya and Transmutación. 574 584UNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASComo el vientoas well as in a good part of prose worksrevista de investigación musical: territorios para el arte 590908 2021 7 8182087 ¿Por qué la literatura? Rodríguez Hernández2386-8260 13268 ItamarRosa María In poetrythe rhythm of words is the music that governs reason and emotion. Literature occupies an important place in my creation. In this article I describe the different procedures in which I configure its presence in my music and the main themes in four of my works: Envoi
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Anti-proliferative and pro-apoptotic activities of hydroxytyrosol on different tumour cells: the role of extracellular production of hydrogen peroxide

2011

Several recently published data suggest that the anti-proliferative and pro-apoptotic properties of hydroxytyrosol [3,4-dihydroxyphenyl ethanol (3,4-DHPEA)] on HL60 cells may be mediated by the accumulation of hydrogen peroxide (H2O2) in the culture medium. The aim of this study was to clarify the role played by H2O2 in the chemopreventive activities of 3,4-DHPEA on breast (MDA and MCF-7), prostate (LNCap and PC3) and colon (SW480 and HCT116) cancer cell lines and to investigate the effects of cell culture medium components and the possible mechanisms at the basis of the H2O2-producing properties of 3,4-DHPEA. The proliferation was measured by the MTT assay and the apoptosis by both fluores…

Medicine (miscellaneous)ApoptosisAntioxidantsCulture Media Serum-FreeSuperoxide dismutaseInhibitory Concentration 50chemistry.chemical_compoundCell Line TumorNeoplasmsPyruvic AcidLNCaPExtracellularHumansMTT assayHydroxytyrosolTumour cellsHydrogen peroxideCell ProliferationNutrition and DieteticsbiologyApoptosiOlive oil Tumour cellsHydrogen-Ion ConcentrationPhenylethyl AlcoholOxidantsHydrogen peroxideAntineoplastic Agents PhytogenicOxygenKineticsHydroxytyrosol; Apoptosis; Hydrogen peroxide; Olive oil; Tumour cellsBiochemistrychemistryDrug Resistance NeoplasmCell cultureCatalaseCulture Media Conditionedbiology.proteinSettore BIO/14 - FarmacologiaHydroxytyrosolOxidoreductasesOxidation-ReductionOlive oil
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Synthesis, characterization and electrochemistry of bismuth porphyrins: X-ray crystal structure of (OEP)Bi(SO3CF3)

2000

The metalation of several free base porphyrins by the bismuth salts Bi(NO3)3 and Bi(SO3CF3)3 in DMF or pyridine is described. The resulting stable Bi(III) porphyrin complexes are characterized by electrochemistry, 1H NMR and UV-vis spectroscopy. The structure of ( OEP ) Bi ( SO 3 CF 3) was also determined by single-crystal X-ray diffraction and shows that ( OEP ) Bi ( SO 3 CF 3) exists as a dimer which is stabilized by electrostatic interactions in which the two [(OEP)Bi]+ cations are linked via oxygen atoms of two symmetrically related [Formula: see text] anions, leading to a heptacoordinated bismuth center. Electrochemical oxidation of ( OEP ) Bi ( SO 3 CF 3) and ( T p TP ) Bi ( SO3CF3 )…

MetalationDimerInorganic chemistrychemistry.chemical_elementFree baseGeneral ChemistryCrystal structureElectrochemistryPorphyrinBismuthchemistry.chemical_compoundCrystallographychemistryPyridineJournal of Porphyrins and Phthalocyanines
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Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications

2017

Mitochondria play a key role in maintaining cellular metabolic homeostasis. These organelles have a high plasticity and are involved in dynamic processes such as mitochondrial fusion and fission, mitophagy and mitochondrial biogenesis. Type 2 diabetes is characterised by mitochondrial dysfunction, high production of reactive oxygen species (ROS) and low levels of ATP. Mitochondrial fusion is modulated by different proteins, including mitofusin-1 (MFN1), mitofusin-2 (MFN2) and optic atrophy (OPA-1), while fission is controlled by mitochondrial fission 1 (FIS1), dynamin-related protein 1 (DRP1) and mitochondrial fission factor (MFF). PARKIN and (PTEN)-induced putative kinase 1 (PINK1) partici…

MiD51 mitochondrial dynamics proteins of 51 kDaΔΨm mitochondrial membrane potential0301 basic medicineMitochondrial fission factorClinical BiochemistryMitochondrial DegradationMFN2Review ArticleTXNIP thioredoxin interacting proteinMitochondrial DynamicsBiochemistryAdenosine TriphosphateGRP78 78 kDa glucose-regulated proteinMFF mitochondrial fission factorMFN2 mitofusin 2TRX2 thioredoxin 2Redox biologylcsh:QH301-705.5NF-κB nuclear factor kappa Blcsh:R5-920MitophagyType 2 diabetesDRP1 dynamin-related protein 1FIS1 fission protein 1BNIP3 BCL2/adenovirus E1B 19 kDa interacting protein 3MitochondriaOPA1 optic atrophy 1SIRT1/3 sirtuin 1/3Biochemistrymitochondrial fusionTGF-β1 transforming growth factor-β1Mitochondrial fissionOMM outer mitochondrial membranelcsh:Medicine (General)MiD49 mitochondrial dynamics proteins of 49Nox 4 NADPH oxidase-4IMM inner mitochondrial membraneFIS1ATF6 activating transcription factor 6PINK1mTOR mammalian target of rapamycinCHOP C/EBP homologous proteinBiologymdivi-1 mitochondrial division inhibitor-1Mitochondrial Proteins03 medical and health sciencesROS reactive oxygen speciessXBP1 spliced X-box binding protein 1UCP-1 uncoupling protein-1MFN1 mitofusin 1SOD superoxide dismutaseLC3 1 A/1B-light chain 3HumansPINK1 (PTEN)-induced putative kinase 1S3 15-OxospiramilactoneOrganic ChemistrymtDNA mitochondrial DNAAMPK AMP-activated protein kinase030104 developmental biologyDiabetes Mellitus Type 2Mitochondrial biogenesislcsh:Biology (General)Oxidative stressp38 MAPK p38 mitogen-activated protein kinasep62/SQSTM1 ubiquitin and sequestosome-1Reactive Oxygen SpeciesRedox Biology
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Genes, Ageing and Longevity in Humans: Problems, Advantages and Perspectives.

2006

Many epidemiological data indicate the presence of a strong familial component of longevity that is largely determined by genetics, and a number of possible associations between longevity and allelic variants of genes have been described. A breakthrough strategy to get insight into the genetics of longevity is the study of centenarians, the best example of successful ageing. We review the main results regarding nuclear genes as well as the mitochondrial genome, focusing on the investigations performed on Italian centenarians, compared to those from other countries. These studies produced interesting results on many putative "longevity genes". Nevertheless, many discrepancies are reported, l…

Mitochondrial DNAAgingProteasome Endopeptidase ComplexNuclear geneApolipoproteins geneticsInsulin-Like Growth Factor I geneticsmedia_common.quotation_subjectApolipoprotein E4LongevityBiologyGenetic polymorphisms ageing longevity centenarians association studies mitochondrial DNABiochemistryDNA MitochondrialInflammation geneticsApolipoprotein E4 geneticsCytokines geneticsAnimalsHumansAlleleInsulin-Like Growth Factor ILongevity geneticsGenemedia_commonGenetic associationGeneticsAged 80 and overInflammationPolymorphism GeneticAryldialkylphosphataseSuperoxide DismutaseLongevitySuperoxide Dismutase geneticsGeneral MedicineClusterin geneticsPoly(ADP-ribose) Polymerases geneticsAging geneticsApolipoproteinsClusterinTumor Suppressor Protein p53 geneticsGenesEvolutionary biologyTraitCytokinesGene poolPoly(ADP-ribose) PolymerasesTumor Suppressor Protein p53Aryldialkylphosphatase geneticsDNA Mitochondrial geneticsProteasome Endopeptidase Complex physiology
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Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD+/-): a novel approach to assess the role of oxidative stress for the develo…

2005

Nitroglycerin (GTN)-induced tolerance was reported to be associated with increased levels of reactive oxygen species (ROS) in mitochondria. In the present study, we further investigated the role of ROS for the development of nitrate tolerance by using heterozygous manganese superoxide dismutase knock-out mice (Mn-SOD+/-). Mn-SOD is acknowledged as a major sink for mitochondrial superoxide. Vasodilator potency of mouse aorta in response to acetylcholine and GTN was assessed by isometric tension studies. Mitochondrial ROS formation was detected by 8-amino-5-chloro-7-phenylpyrido[3,4-d]pyridazine-1,4-(2H,3H)dione sodium salt (L-012)-enhanced chemiluminescence and mitochondrial aldehyde dehydro…

Mitochondrial ROSHeterozygoteAldehyde dehydrogenaseMitochondrionPharmacologymedicine.disease_causeMitochondria HeartSuperoxide dismutaseMiceNitroglycerinDrug tolerancemedicineAnimalsEndothelial dysfunctionAortaPharmacologychemistry.chemical_classificationReactive oxygen speciesbiologySuperoxide DismutaseDrug ToleranceAldehyde Dehydrogenasemedicine.diseaseEnzyme ActivationMice Inbred C57BLOxidative StresschemistryBiochemistrycardiovascular systembiology.proteinMolecular MedicineOxidative stresscirculatory and respiratory physiologyMolecular pharmacology
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Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dys…

2008

AimsImbalance between pro- and antioxidant species (e.g. during aging) plays a crucial role for vascular function and is associated with oxidative gene regulation and modification. Vascular aging is associated with progressive deterioration of vascular homeostasis leading to reduced relaxation, hypertrophy, and a higher risk of thrombotic events. These effects can be explained by a reduction in free bioavailable nitric oxide that is inactivated by an age-dependent increase in superoxide formation. In the present study, mitochondria as a source of reactive oxygen species (ROS) and the contribution of manganese superoxide dismutase (MnSOD, SOD-2) and aldehyde dehydrogenase (ALDH-2) were inves…

Mitochondrial ROSMaleAgingPhysiologyVasodilator AgentsMitochondrionVascular dysfunctionmedicine.disease_causeMitochondria HeartMuscle Smooth Vascularchemistry.chemical_compoundMiceEndothelial dysfunctionAortachemistry.chemical_classificationMice KnockoutbiologySuperoxideAldehyde Dehydrogenase MitochondrialAge FactorsVasodilationBiochemistryCardiology and Cardiovascular MedicineMitochondrial aldehyde dehydrogenasemedicine.medical_specialty8-oxodGOxidative phosphorylationDNA MitochondrialSuperoxide dismutaseManganese superoxide dismutaseddc:570Physiology (medical)Internal medicinemedicineAnimalsReactive oxygen speciesDose-Response Relationship DrugSuperoxide DismutaseMitochondrial oxidative stressOriginal ArticlesAldehyde Dehydrogenasemedicine.diseaseMice Inbred C57BLOxidative StressEndocrinologychemistrybiology.proteinEndothelium VascularReactive Oxygen SpeciesOxidative stressDNA DamageCardiovascular research
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Mitochondrial oxidative stress and nitrate tolerance – comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD+/- mice

2006

Abstract Background Chronic therapy with nitroglycerin (GTN) results in a rapid development of nitrate tolerance which is associated with an increased production of reactive oxygen species (ROS). According to recent studies, mitochondrial ROS formation and oxidative inactivation of the organic nitrate bioactivating enzyme mitochondrial aldehyde dehydrogenase (ALDH-2) play an important role for the development of nitrate and cross-tolerance. Methods Tolerance was induced by infusion of wild type (WT) and heterozygous manganese superoxide dismutase mice (Mn-SOD+/-) with ethanolic solution of GTN (12.5 μg/min/kg for 4 d). For comparison, the tolerance-free pentaerithrityl tetranitrate (PETN, 1…

Mitochondrial ROSMaleHeterozygotelcsh:Diseases of the circulatory (Cardiovascular) systemVasodilator AgentsAldehyde dehydrogenaseOxidative phosphorylationMitochondrionPharmacologyIn Vitro Techniquesmedicine.disease_causeDrug Administration ScheduleMitochondria HeartCell LineSuperoxide dismutaseMiceNitroglycerinmedicineAnimalsHumansPentaerythritol TetranitrateRNA MessengerRats WistarHeart metabolismAortachemistry.chemical_classificationReactive oxygen speciesbiologybusiness.industrySuperoxide DismutaseAldehyde Dehydrogenase MitochondrialBilirubinDrug ToleranceFree Radical ScavengersAldehyde DehydrogenaseAcetylcholineRatsVasodilationOxidative Stresschemistrylcsh:RC666-701Anesthesiabiology.proteinCardiology and Cardiovascular MedicinebusinessReactive Oxygen SpeciesOxidative stressHeme Oxygenase-1Research ArticleBMC Cardiovascular Disorders
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