Search results for "SoMe"

Extraction, Characterization and Incorporation of Hypericum scruglii Extract in Ad Hoc Formulated Phospholipid Vesicles Designed for the Treatment of…

2020

An extract of Hypericum scruglii, an endangered endemic plant of Sardinia (Italy), was prepared and characterized. It was loaded in special phospholipid vesicles, glycerosomes, which were modified by adding maltodextrin (glucidex) and a polymer (gelatin or hyaluronan). The corresponding liposomes were also prepared and used as reference. The vesicles disclosed suitable physicochemical features for skin delivery. Indeed, their mean diameter ranged from 120 to 160 nm, they were homogeneously dispersed (polydispersity index &le

Unilateral Maximal Isometric Hex Bar Pull Test: Within-Session Reliability and Lower Body Force Production in Male and Female Freeski Athletes

2021

The aim of the study was to (1) assess the within-session reliability of a unilateral isometric hex bar pull (UIHBP) maximal voluntary contraction (MVC) test and, (2) determine unilateral isometric absolute peak force (PFabs) and relative peak force (PF) values in freeski athletes. Twenty-one male and eight female academy to national team freeskiers performed the novel UIHBP MVC task on a force plate and PFabs and relative PF were assessed (1000 Hz). Within-session measures of PFabs offered high reliability on left and right limbs for males (ICC = 0.91–0.94, CV = 2.6–2.2%) and females (ICC = 0.94–0.94, CV = 1.4–1.6%), while relative PF measures showed good to high reliability in both left a…

Effect of exosomes released from K562 CML cell line on gamma-delta T cells function

2012

Università in scena. Il campo dei Gasometri "nuovo porto" sulla direttrice nord-ovest

2016

Nel progetto per il nuovo insediamento della Bovisa prende corpo il confronto tra due scale, due misure del progetto di architettura. La prime, quella "dell'idea di città" riferita al principio ordinatore della direttrice nord-ovest; infatti, come altrove rimarcato, Milano è da sempre città di dimensioni contenute ma di rapporti territoriali estesi, storicamente radicata a un sistema di itinerari e direttrici di lunga e breve distanza, che si riflette nella compresenza delle diverse scale, appunto, con progetti e realizzazioni che evocano i grandi spazi congeniali a questo carattere di portualità.

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS

2007

Membrane fission is an essential process in membrane trafficking and other cellular functions. While many fissioning and trafficking steps are mediated by the large GTPase dynamin, some fission events are dynamin independent and involve C-terminal-binding protein-1/brefeldinA-ADP ribosylated substrate (CtBP1/BARS). To gain an insight into the molecular mechanisms of CtBP1/BARS in fission, we have studied the role of this protein in macropinocytosis, a dynamin-independent endocytic pathway that can be synchronously activated by growth factors. Here, we show that upon activation of the epidermal growth factor receptor, CtBP1/BARS is (a) translocated to the macropinocytic cup and its surroundi…

Binocular vision alterations after refractive and cataract surgery: a review.

2018

To review binocular and accommodative disorders documented after corneal or intraocular refractive surgery, in normal healthy prepresbyopic patients. A bibliographic revision was performed; it included works published before 1st July 2017 where accommodation and/or binocularity was assessed following any type of refractive surgical procedure. The search in Pubmed yielded 1273 papers, 95 of which fulfilled the inclusion criteria. Few publications reporting binocular vision and/or accommodative changes after refractive surgery in normal subjects were found. The reduction in fusional vergence is the most frequently reported alteration. Anisometropia is an important risk factor for postoperativ…

Intrachromosomal Telomeric Sequences Distribution in Ceboidea Can Reveal Insights into the Chromosomal Evolution in New World Primates

2015

Seed dispersal by ants: are seed preferences influenced by foraging strategies or historical constraints?

2003

Summary The objective of this study was to quantify preferences of ants for seeds of different plant species and to test if these preferences were caused by foraging strategies or by historical constraints. We compared seed removal rates of ten different ant-dispersed plant species found in temperate forests, along forest edges and in grassland. We found significant differences in seed removal rates among the ten species. To test if these differences were caused by foraging strategies we examined the relationship between seed and elaiosome size and seed removal rate. We found that seeds with larger elaiosomes had significantly higher removal rates. To test the historical constraint hypothes…

Morphometric indices as indicators of tectonic, fluvial and karst processes in calcareous drainage basins, South Menorca Island, Spain

2007

This study proposes using morphometric indices to discriminate the processes that shape calcareous drainage basins. To illustrate this, a DEM of the southern part of Menorca Island (Migjorn) was created and basin slope, drainage density, hypsometric curve and integral, and the area occupied by open and closed dolines were extracted from it. These indices show an important dependence on tectonics, which govern the morphology of these drainage basins and encourage the predominance of karst and/or fluvial processes in the different sectors. The morphometric indices are clearly influenced by the geological Migjorn structure, a carbonate Upper Miocene reef platform gently folded as an asymmetric…

1,4 dihidropiridinski derivati povećavaju ekspresiju gena Psma3, Psmb5 i Psmc6 u glasničkoj RNA štakora

2021

The ubiquitin-proteasome system modifies different cellular and protein functions. Its dysregulation may lead to disrupted proteostasis associated with multiple pathologies and aging. Pharmacological regulation of proteasome functions is already an important part of the treatment of several diseases. 1,4-dihydropyridine (1,4-DHP) derivatives possess different pharmacological activities, including antiaging and neuroprotective. The aim of this study was to investigate the effects of several 1,4-DHP derivatives on mRNA expression levels of proteasomal genes Psma3, Psmb5, and Psmc6 in several organs of rats. Rats were treated with metcarbatone, etcarbatone, glutapyrone, styrylcarbatone, AV-153…