Search results for "Solubility"
showing 10 items of 681 documents
Probleme polnischer Moraltheologen mit dem nachsynodalen apostolischen Schreiben von Papst Franziskus Amoris laetitia
2020
Amoris laetitia, the post-synodal Exhortation of Pope Francis, provoked varied reactions among theologians. Especially controversial is the question of the admission of divorced people living in civil partnership to the sacraments of penance and reconciliation and the Eucharist. The present text presents the main arguments of Polish moral theologians, which came to the fore during the discussion on the practice of sacrament for divorced and remarried people. The Polish theologians’ arguments cited are not limited to simply quoting the teachings of Pope John Paul II, but refer to important arguments from the theology of marriage, theology of sacraments and moral theology. The author indicate…
Hyaluronan Graft Copolymers Bearing Fatty-Acid Residues as Self-Assembling Nanoparticles for Olanzapine Delivery
2019
In order to evaluate the potential of a technology platform based on hyaluronan copolymers grafted with propargylated ferulate fluorophores (HA-FA-Pg) in the development of drug delivery systems, the propargyl groups of HA-FA-Pg derivatives were employed with oleic acid (OA) or stearic acid (SA) residues across a biocompatible hexa(ethylene glycol) (HEG) spacer. The designed materials (i.e., HA-FA-HEG-OA or HA-FA-HEG-SA) showed clear-cut aggregation features in an aqueous environment, as confirmed by dynamic light scattering (DLS) and transmission electron microscopy (TEM), generating nanoaggregate systems. In fact, HA-FA-HEG-OA and HA-FA-HEG-SA derivatives showed the property to create sel…
Ethyl hexanoate transfer in paper and plastic food packaging by sorption and permeation experiments
2008
The barrier properties of one treated paper packaging and one standard plastic film (bi-oriented polypropylene, biOPP) were assessed for ethyl hexanoate. Three methods based either on sorption (gravimetry and micro-atmosphere-derived method) or permeation kinetic determination were used in controlled conditions of aroma vapor concentration (107 Pa), temperature (25 degrees C) and relative humidity (about 0 %). Ethyl hexanoate solubility values were on the same range of magnitude for both packaging films in spite of their different nature and composition. Ethyl hexanoate affinity for both films was well predicted by their respective solubility parameters. Solubility values were different acc…
In Vitro Evaluation of Poly(lactide-co-glycolide) In Situ Forming Gels for Bedaquiline Fumarate Salt and Pharmacokinetics Following Subcutaneous Inje…
2021
This study evaluated in vitro and in vivo drug release of bedaquiline from in situ forming gels (ISGs) containing 200 mg eq./g bedaquiline fumarate salt prepared with four different grades of poly(d,l-lactide) (PDLLA) or poly(d,l-lactide-co-glycolide) (PLGA) with a lactide/glycolide ratio of 50/50 or 75/25 and acid (A) or ester (E) end-capping in N-methyl-2-pyrrolidone at a polymer/solvent ratio of 20/80% (w/w). Mean in vitro drug release in 0.05 M phosphate buffer pH 7.4 with 1% (w/v) sodium lauryl sulphate was 37.3, 47.1, 53.3, and 62.3% within 28 days for ISGs containing PLGA5050A, PDLLA, PLGA7525A, and PLGA7525E, respectively. The data suggested that drug release was primarily controlle…
Physico-chemical characterisation of a non-conventional food protein source from earthworms and sensory impact in arepas
2009
International audience; This study aimed to characterise a non-conventional protein source: a powder made from earthworms, and to evaluate its potential use as human food. The way it was prepared led to low solubility and wide particle size distribution. Sensory analysis was used to assess the acceptability and the organoleptic properties of maize-based pan-cakes fortified with this novel protein powder. Satisfying products were obtained with a substitution level of 5.5% (w/w) earthworm powder in pan-cakes. GC-MS allowed the identification of more than seventy volatile compounds that may be responsible for the off-odour of the powder. The most abundant chemical groups found in the volatile …
Proteins in Ionic Liquids: Reactions, Applications, and Futures
2019
Biopolymer processing and handling is greatly facilitated by the use of ionic liquids, given the increased solubility, and in some cases, structural stability imparted to these molecules. Focussing on proteins, we highlight here not just the key drivers behind protein-ionic liquid interactions that facilitate these functionalities, but address relevant current and potential applications of protein-ionic liquid interactions, including areas of future interest.
The dissolution of gypsum of Disueri reservoir left bank
2011
Results of a laboratory research programme on the rate of dissolution of selenitic gypsum are reported and discussed. The tested gypsum samples have been recovered from boreholes drilled in a thick layer outcropping on the left bank of Disueri reservoir located near Gela in Sicily. The tests carried out demonstrate that the rate of dissolution Rd depends essentially upon the velocity v of water flowing over the surface of the gypsum. Values of Rd range from 0.94 to 3 kg/(m2 • day) for v values from 0.05 to 0.20 m/s. Such high rates can account both for the rapid evolution of the existing cavities and for the creation of new caves within the gypsum mass subsequent to the impounding of the re…
A fluorescence study of the loading and time stability of doxorubicin in sodium cholate/PEO-PPO-PEO triblock copolymer mixed micelles
2019
Abstract Hypothesis Doxorubicin hydrochloride (DX) is one of the most powerful anticancer agents though its clinical use is impaired by severe undesired side effects. DX encapsulation in nanocarrier systems has been introduced as a mean to reduce its toxicity. Micelles of the nonionic triblock copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) (PEO-PPO-PEO), are very promising carrier systems. The positive charge of DX confines the drug to the hydrophilic corona region of the micelles. The use of mixed micelles of PEO-PPO-PEO copolymers and a negatively charged bile salt should favour the solubilization of DX in the apolar core region of the micelles. Experiments We st…
Structural Motifs of Alkali Metal Superbases in Non‐coordinating Solvents
2020
Abstract Lochmann–Schlosser superbases (LSB) are a standard reagent in synthetic chemistry to achieve an exchange of a proton on an organic framework with an alkali metal cation, which in turn can be replaced by a wide range of electrophilic groups. In standard examples, the deprotonating reagent consists of an equimolar mixture of n‐butyllithium and potassium t‐butoxide. However, the nature of the reactive species could not be pinned down either for this composition or for similar mixtures with comparable high reactivity. Despite the poor solubility and the fierce reactivity, some insights into this mixture were achieved by some indirect results, comparison with chemically related systems,…
Uzasadnienie nierozerwalności małżeństwa w ujęciu protestanckim
2017
Obchody 500. rocznicy Reformacji są okazją do refleksji nad istotnymi treściami tradycji i teologii protestanckiej. Jedną ze szczegółowych kwestii jest nauka o nierozerwalności małżeństwa, która w powszechnym przekonaniu charakteryzuje katolickie rozumienie małżeństwa. W odróżnieniu od tego przyjmuje się, że w protestantyzmie dopuszczalne są rozwody. Analizując wypowiedzi ojców Reformacji, a także teksty teologów i dokumenty Kościołów tradycji poreformacyjnej, dochodzimy do przekonania, że istotnym elementem rozumienia małżeństwa jest jego nierozerwalność i trwałość, choć jednocześnie w określonych okolicznościach dopuszczalne są rozwody i możliwe jest zawarcie ponownego małżeństwa z błogos…