Search results for "Soma"
showing 10 items of 2624 documents
"Mitä sä luulet olevas?" : Suomessa asuvien ja yhteiskunnallisesti aktiivisten somalinaisten kamppailu identiteeteistään
2010
Tutkimuksessa on tarkasteltu Suomessa asuvia ja yhteiskunnallisesti aktiivisia somalinaisia tarkoituksena selvittää, kuinka naisten eri toimintaympäristöt vaikuttavat heidän identiteetteihinsä. Suomalainen yhteiskunta, Suomen somaliyhteisö sekä Somalia/Somalimaa muodostavat ne kolme toimintaympäristöä, joissa naiset toimivat ja joissa heidän identiteettinsä joutuvat kyseenalaistetuiksi. Tutkimuksen näkökulman mukaan identiteettimme ovat jatkuvassa muutoksessa ja yksilöinä peilaamme omaa identiteettiämme ympäristöstämme tulevia vaatimuksia ja odotuksia vastaan. Tämä ”kamppailu” identiteeteistä ilmenee niin taisteluna legitimaation ja tunnustuksen saamiseksi muilta ryhmiltä kuin kieltäytymise…
Targeting the tumor mutanome for personalized vaccination therapy
2012
Next generation sequencing enables identification of immunogenic tumor mutations targetable by individualized vaccines. In the B16F10 melanoma system as pre-clinical proof-of-concept model, we found a total of 563 non-synonymous expressed somatic mutations. Of the mutations we tested, one third were immunogenic. Immunization conferred in vivo tumor control, qualifying mutated epitopes as source for effective vaccines.
Impact of pharmacological and environmental manipulations on neuronal structural plasticity and dynamics
2017
El sistema nervioso de vertebrados es uno de los más estudiados, aunque peor comprendidos, del organismo de mamíferos. Desde que Ramón y Cajal postuló su teoría celular de este sistema (Ramón y Cajal 1909), la neurona se ha postulado como su unidad funcional. Sin embargo, durante las últimas décadas se ha revolucionado la visión que se tenía de éste. Una de las percepciones más asentadas era que, tras el desarrollo embrionario, el sistema nervioso se mantenía inmutable. Sin embargo, ahora sabemos que diferentes formas de plasticidad gobiernan su adaptación, que son necesarias para importantes procesos del día a día, tales como el aprendizaje y la memoria (Smythies 2002; Berlucchi and Buchte…
Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex
2014
Highlights • We characterise Sas3p and Gcn5p active HAT complexes in WT and deleted TAP-strains. • We confirm that Pdp3p interacts with NuA3, histones and chromatin regulators. • Pdp3p MS-analysis reveals its phosphorylation, ubiquitination and methylation. • Sas3p can substitute Gcn5p in acetylation of histone H3K14 but not of H3K9. • Genome-wide profiling of Sas3p supports its involvement in transcriptional elongation.
Enerģētiskā substrāta izmantojamība standartizētā augošā slodzē jaunietēm ar atšķirīgām somatotipa iezīmēm
2015
Darba mērķis bija noteikt enerģētiskā substrāta komponentu- lipīdu un ogļhidrātu, izmantojamību augošā fiziskā slodzē praktiski veselām, fiziski netrenētām jaunietēm ar atšķirīgu adipozo audu masu. Mērķa sasniegšanai tika veikti antropometriskie mērījumi, lai noteiktu indivīdu somatotipu, relatīvo tauku masu un ķermeņa masas indeksu. Ogļhidrātu un lipīdu izmantošana tika noteikta ar netiešās kalorimetrijas metodi augošas fiziskas slodzes testā. Rezultāti liecina, ka studējošo jauniešu grupā ķermeņa veidolā dominē endomorfijas un mezomorfijas pazīmes. Personām ar atšķirīgu taukaudu masu maksimālā lipīdu oksidācija fiziskas slodzes laikā tiek panākta pie atšķirīgām skābekļa patēriņa vērtībām.…
Sedentary Patterns and Sit-to-Stand Transitions in Open Learning Spaces and Conventional Classrooms among Primary School Students
2022
Educational reforms worldwide have resulted in schools increasingly incorporating open and flexible classroom designs that may provide possibilities to reduce sedentary behavior among students during lessons. Cross-sectional associations of classroom type on accelerometry assessed sedentary bout durations and sit-to-stand transitions were investigated in 191 third and fifth grade students recruited from one school with open learning spaces and two schools with conventional classrooms. A three-way ANOVA for classroom type, gender and grade level indicated that students in open learning spaces had more 1-to-4-min sedentary bouts (mean difference 1.8 bouts/h, p 10-min sedentary bouts (median 0…
Naisesimiesten työhyvinvointi vuosina 1996 ja 1999 ja sitä selittävät tekijät
2000
Análisis poblacional y filogeográfico de vectores de la enfermedad de Chagas en Perú basado en análisis multigénicos del ADN ribosomal y mitocondrial
2017
La enfermedad de Chagas, cuyo agente causal es Trypanosoma cruzi, constituye un grave problema de salud pública en toda Latinoamérica. La principal forma de transmisión es la vectorial, de la que son responsables hemípteros redúvidos de la subfamilia Triatominae adaptados a los hábitats doméstico y peridoméstico. Puesto que el parásito se mantiene en un ciclo zoonótico silvestre y es imposible de eliminar, la principal forma de lucha contra la transmisión vectorial consiste en la eliminación de las poblaciones domiciliadas del vector. Los estudios moleculares constituyen una herramienta de gran utilidad a la hora de planificar las campañas de control vectorial, puesto que permiten conocer y…
Somatic Embryogenesis and Plant Regeneration from Hypocotyl Cultures of Digitalis obscura L.
1986
Summary Hypocotyl sections from 20-day-old seedlings of Digitalis obscura L. were used to examine the effect of IAA on somatic embryogenesis. Although embryogenesis was obtained with all IAA concentrations (0.1, 0.5 and 1 ppm) and under both illumination conditions tested (16 h photoperiod and darkness), incubation in photoperiod increased yield of embryos and shortened the embryo induction time. Optimum results were obtained with 1 ppm IAA. About 30 % of the embryos obtained developed into complete plantlets when transferred to basal medium without growth regulators.
Early evolutionary colocalization of the nuclear ribosomal 5S and 45S gene families in seed plants: evidence from the living fossil gymnosperm Ginkgo…
2012
In seed plants, the colocalization of the 5S loci within the intergenic spacer (IGS) of the nuclear 45S tandem units is restricted to the phylogenetically derived Asteraceae family. However, fluorescent in situ hybridization (FISH) colocalization of both multigene families has also been observed in other unrelated seed plant lineages. Previous work has identified colocalization of 45S and 5S loci in Ginkgo biloba using FISH, but these observations have not been confirmed recently by sequencing a 1.8 kb IGS. In this work, we report the presence of the 45S–5S linkage in G. biloba, suggesting that in seed plants the molecular events leading to the restructuring of the ribosomal loci are much o…