Search results for "Sonia"
showing 10 items of 86 documents
Mesonia oceanica sp. Nov., isolated from oceans during the tara oceans expedition, with a preference for mesopelagic waters
2020
10 pages, 4 figures, 3 tables
In vitro activity of linezolid, clarithromycin and moxifloxacin against clinical isolates of Mycobacterium kansasii
2005
To compare the activity of linezolid with a range of drugs used in the treatment of Mycobacterium kansasii infections.The percentages of resistant isolates against isoniazid, rifampicin and ethambutol were 2.9%, 1.9% and 2.9%, respectively. All isolates were susceptible to clarithromycin and moxifloxacin both with MIC(90) values of 0.125 mg/L. Linezolid was active against all isolates with MIC(50) and MIC(90) values of 0.5 and 1 mg/L, respectively, both below the susceptibility breakpoint established for mycobacteria.Linezolid, clarithromycin or moxifloxacin, could be used as alternative drugs for treatment of infections due to rifampicin-resistant isolates as well as short-course or interm…
Die synergistische Wirkung von INH und 6-(Sulfanilamido)-2,4-dimethylpyrimidin gegen resistente Tuberkelbakterienstämme (in vitro-Versuche)
1954
INH (Rimifon) und 6-(Sulfanilamido)-2,4-Dimethylpyrimidin (Aristamid) haben eine synergistische Wirkung gegen sensible und gegen streptomycin- und INH-resistente Tuberkelbakterien-Stamme.
Phylogeny and inflorescences of Berberidaceae — a morphological survey
1995
The 13 genera of Berberidaceae are investigated morphologically and cladistically in order to examine the phylogenetic relationships among the extant taxa. Cladistic analysis of 59 morphological characters using PAUP resulted in one most parsimonious tree. In the present paper main emphasis is put on inflorescence morphological features, which contributes eight characters to the current data matrix. The analysis resulted in four major clades. Nandina has a basal position, and the next clade includes Berberis and Mahonia. Ranzania is sister genus to Jeffersonia, Diphylleia/Podophyllum and Leontice/Bongardia. These all form the sister group to a clade in which Achlys is sister taxon to Epimed…
Learning to synthesize contradictions: An Austrian Approach to Bridging Time Concepts in the Theory of the Firm
2008
By analysing the implcit assumptions regarding time underlying the theories of the resource based firm, and analysing the views they portray, we propose a theoretical framework which allows to bridge balue creation and value appropriation issues in strategy studies.
Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants.
2010
Mutations in the DJ-1 gene cause autosomal recessive, early-onset Parkinsonism. The DJ-1 protein exerts a protective role against oxidative stress damage, working as a cellular oxidative stress sensor, and it seems to regulate gene expression at different levels. In Drosophila, two DJ-1 orthologs have been identified: DJ-1β and DJ-1β. Several studies have shown that loss of DJ-1β function causes Parkinson's disease (PD)-like phenotypes in flies such as age-dependent locomotor defects, reduced lifespan, and enhanced sensitivity to toxins that induce oxidative stress, like the herbicide paraquat. However, no dopaminergic neurodegeneration is observed. These results suggested that both locomot…
Imaging of Substantia Nigra in Parkinson's Disease: A Narrative Review.
2021
Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized by motor and non-motor symptoms due to the degeneration of the pars compacta of the substantia nigra (SNc) with dopaminergic denervation of the striatum. Although the diagnosis of PD is principally based on a clinical assessment, great efforts have been expended over the past two decades to evaluate reliable biomarkers for PD. Among these biomarkers, magnetic resonance imaging (MRI)-based biomarkers may play a key role. Conventional MRI sequences are considered by many in the field to have low sensitivity, while advanced pulse sequences and ultra-high-field MRI techniques have brought many advantages, partic…
Pisa syndrome after rasagiline therapy in a patient with Parkinson’s disease
2015
Dear Editor, We have read with interest comments by Solla et al. [1] regarding our Letter to the Editor published in NeurologicalSciences titled ‘‘Insidious onset of Pisa Syndrome afterrasagiline therapy in a patient with Parkinson’s Disease’’[2]. We thank the authors for their interest in our paper, but we think it is necessary to make some clarifications regarding the temporal relationship between the onset of Pisa Syndrome (PS) and rasagiline therapy. PS occurred in fact after and not before rasagiline treatment as stated by Solla et al. In particular, PS occurred after a time interval of 6–12 months and anyway after rasagiline was added to patient’s therapy. This long time interval is o…
Severe tuberculous meningoencephalitis in a 30-year old woman with active systemic lupus erythematosus.
1997
Tuberculosis is a significant cause of morbidity and mortality in immunocompromising diseases such as systemic lupus erythematosus (SLE). It often is difficult to distinguish between central nervous system (CNS) involvement and infectious complications in SLE. We report the case of a 30-year-old woman with active SLE and severe tuberculous meningoencephalitis. The diagnosis of tuberculous meningoencephalitis was confirmed by cerebrospinal fluid culture examination, which revealed mycobacterium tuberculosis and typical findings for tuberculous meningoencephalitis on magnetic resonance imaging. Despite treatment with isoniazid, rifampicin, ethambutol, streptomycin, and prednisone, the patient…
Behavioural studies on rats injected with l-cycloserine and other compounds
1964
l-cycloserine, a cyclic derivative of O-substituted hydroxylamine, causes the suppression of the conditioned avoidance reaction in the rat. The subsequent injection of equimolar amounts of pyridoxine hydrochloride is responsible for a complete reversal of this suppression. The suppression of the conditioned response is not observed with the d-isomer of cycloserine. Isoniazid is a strong antagonist of l-cycoserine. Changes in the brain level of GABA under several conditions are described. These changes suggest though do not establish a relationship between the block of the conditioned response and the elevation of the aminoacid above its physiological concentration.