Search results for "Soysal P."

showing 10 items of 50 documents

Sarcopenia and health-related outcomes: an umbrella review of observational studies

2019

Key summary pointsAimTo investigate associations of sarcopenia with adverse health-related outcomes, through an umbrella review method.FindingsSarcopenia appears to be significantly associated with several adverse outcomes in older people, with a strong evidence for increased risk of mortality, disability, and falls.MessageSarcopenia is associated with several adverse health-related outcomes in older people, indicating the need of assessing this condition in daily practice. AbstractBackgroundThe clinical relevance of sarcopenia has increasingly been recognized. However, whether it is associated with the development of other medical conditions is still unclear. Therefore, we aimed to capture…

GerontologySarcopeniaan umbrella review of observational studies- EUROPEAN GERIATRIC MEDICINE cilt.10 ss.853-862 2019 [Veronese N. Demurtas J. SOYSAL P. Smith L. Torbahn G. Schoene D. Schwingshackl L. Sieber C. Bauer J. Cesari M. et al. -Sarcopenia and health-related outcomes]Psychological intervention03 medical and health sciencesUmbrella review0302 clinical medicinemedicineFallClinical significanceMeta-analysi030212 general & internal medicineMortalityDisability030214 geriatricsbusiness.industryHealth relatedOdds ratiomedicine.diseaseConfidence intervalIncreased riskHealthSarcopeniaObservational studyRisk factorbusinesshuman activities
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Role of physical activity in ameliorating neuropsychiatric symptoms in Alzheimer disease: A narrative review

2019

Objective: Neuropsychiatric symptoms (NPs) affect almost all patients with Alzheimer disease (AD). Because of the complications associated with the pharmacological treatment, nonpharmacological treatment (such as physical activity) can be considered as an additional complementary treatment option for NPs. The aim of this review is to evaluate the impact of physical activity on NPs in patients with AD. Methods: We searched Pubmed and Google Scholar for potential eligible articles until March 1, 2018. Results: Although there are contradictory results showing the impact of physical exercise on NPs, most of them reported that it had a significant effect on depression and sleep disturbances in p…

Hypothalamo-Hypophyseal SystemPituitary-Adrenal SystemPhysical exerciseDiseaseBioinformatics03 medical and health sciences0302 clinical medicineNeurotrophic factorsAlzheimer DiseasemedicineHumansApathyExerciseDepression (differential diagnoses)030214 geriatricsbusiness.industryMental DisordersAlzheimer disease neuropsychiatric symptoms physical activity physical exercisemedicine.diseaseExercise TherapyPsychiatry and Mental healthDisinhibitionA narrative review- INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY cilt.34 sa.9 ss.1316-1325 2019 [Veronese N. Solmi M. Basso C. Smith L. SOYSAL P. -Role of physical activity in ameliorating neuropsychiatric symptoms in Alzheimer disease]AnxietyGeriatrics and Gerontologymedicine.symptomAlzheimer's diseasebusiness
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Survival time and differences between dementia with Lewy bodies and Alzheimer’s disease following diagnosis: a meta-analysis of longitudinal studies.

2019

Objective: To synthesize the evidence across longitudinal studies comparing survival in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). Methods: We conducted a systematic review and meta-analysis of studies comparing survival in clinically diagnosed DLB to AD. Longitudinal cohort studies were identified through a systematic search of major electronic databases from inception to May 2018. A random effects meta-analysis was performed to calculate survival time and relative risk of death. Results: Overall, 11 studies were identified including 22,952 patients with dementia: 2029 with DLB (mean diagnosis age 76.3; 47% female) compared with 20,923 with AD (mean diagnosis age 77.2; 6…

Lewy Body DiseaseMale0301 basic medicineAgingmedicine.medical_specialtyDiseaseBiochemistryLewy bodie03 medical and health sciences0302 clinical medicineA meta-analysis of longitudinal studies.- Ageing research reviews cilt.50 ss.72-80 2019 [MUELLER C. Soysal P. RONGVE A. ISIK A. THOMPSON T. MAGGI S. SMITH L. Basso C. STEWART R. BALLARD C. et al. -Survival time and differences between dementia with Lewy bodies and Alzheimer-s disease following diagnosis]Alzheimer DiseaseInternal medicinemental disordersmedicineHumansDementiaLongitudinal StudiesLongitudinal cohortMortalityMolecular BiologyAgedDementia with Lewy bodiesbusiness.industryCognitive scoreAlzheimer's diseaseRandom effects modelmedicine.diseaseSurvival RateObservational Studies as Topic030104 developmental biologyNeurologyMeta-analysisRelative riskFemaleDementiabusinessLewy bodiesAlzheimer’s disease030217 neurology & neurosurgeryBiotechnology
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Sociodemographic and behavioural correlates of lifetime number of sexual partners: findings from the English Longitudinal Study of Ageing.

2018

BackgroundNo current data are available on correlates of lifetime sexual partners at older ages. This study aimed to explore correlates of the lifetime number of sexual partners in a sample of older adults.MethodData were from 3054 men and 3867 women aged ≥50 years participating in the English Longitudinal Study of Ageing. Participants reported their lifetime number of sexual partners and a range of sociodemographic characteristics and health behaviours. Multivariable multinomial logistic regression was used to examine correlates of lifetime number of sexual partners, with analyses performed separately for men and women and weighted for non-response.ResultsYounger age, being separated/divor…

Longitudinal studyYounger ageSocial Sciences and HumanitiesSocial Sciences (SOC)Sosyal Bilimler ve Beşeri BilimlerEthnic groupOBSTETRICS & GYNECOLOGYSağlık BilimleriDoğum ve JinekolojiClinical Medicine (MED)SOCIAL SCIENCES BIOMEDICAL0302 clinical medicineSociologyKADIN HASTALIKLARI & DOĞUMSurgery Medicine SciencesKlinik Tıp (MED)030212 general & internal medicineHomosexuality1506older adultsmedia_commonMultinomial logistic regressionKlinik TıpObstetrics and GynecologyGeneral Social SciencesKadın Hastalıkları ve DoğumTıpnumber of sexual partnersCerrahi Tıp BilimleriLife course approachMedicineAİLE ÇALIŞMALARISosyal Bilimler (SOC)0305 other medical sciencePsychologySOSYAL BİLİMLER BİYOMEDİKSELmedia_common.quotation_subjectSOCIAL SCIENCES GENERALnumber of sexual partnerHome Economics03 medical and health sciencesfindings from the English Longitudinal Study of Ageing- BMJ Sex Reprod Health cilt.4 ss.2018-2020 2019 [Jackson S. E. YANG L. López Sánchez G. Veronese N. KOYANAGI A. Grabovac I. SOYSAL P. Smith L. -Sociodemographic and behavioural correlates of lifetime number of sexual partners]Health SciencesGenel Sosyal BilimlerSosyal ve Beşeri BilimlerSocial Sciences & Humanitiessolder adultSosyoloji030505 public healthEv EkonomisiResearchSosyal Bilimler GenelCLINICAL MEDICINEFormer SmokerpredictorsReproductive MedicineAgeingFAMILY STUDIESDemographyBMJ sexualreproductive health
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Mild cognitive impairment is associated with fall-related injury among adults aged ≥65 years in low- and middle-income countries.

2021

Abstract Objectives There is a scarcity of data on the association between mild cognitive impairment (MCI) and falls, especially from low- and middle-income countries (LMICs) where 70% of all older adults reside. Thus, we investigated the association between MCI and fall-related injury among older adults residing in six LMICs (China, Ghana, India, Mexico, Russia, South Africa). Design Cross-sectional, community-based data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. Methods The definition of MCI was based on the National Institute on Ageing-Alzheimer's Association criteria, and information on past 12-month fall-related injury was also collected. Multivariable l…

Male0301 basic medicineChinaAgingIndiaPoison controlLogistic regressionGhanaBiochemistrySuicide preventionOccupational safety and healthRussiaOdds*Low-and-middle-income countriesSouth Africa03 medical and health sciencesOlder adults.0302 clinical medicineEndocrinologyRisk FactorsFall-related injuryInjury preventionmental disorders*Fall-related injuryPrevalenceGeneticsHumansMedicine*Mild cognitive impairmentCognitive DysfunctionDeveloping CountriesMexicoMolecular BiologyAged*Older adultsbusiness.industryConfoundingMild cognitive impairmentHuman factors and ergonomicsSmith L. Jacob L. Kostev K. Butler L. Barnett Y. Pfeifer B. Soysal P. Grabovac I. López-Sánchez G. F. Veronese N. et al. -Mild cognitive impairment is associated with fall-related injury among adults aged ≥65 years in low- and middle-income countries.- Experimental gerontology ss.111222 2020Cell BiologyCross-Sectional Studies030104 developmental biologyLow-and-middle-income countrieAccidental FallsFemalebusiness030217 neurology & neurosurgeryDemography
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The relationship between Polypharmacy and Trajectories of Cognitive Decline in People with Dementia: a large representative cohort study

2019

Polypharmacy, defined through the number of medications prescribed, has been linked to a range of adverse health outcomes in people with dementia. It is however unclear whether a numerical threshold of concurrently prescribed drugs is a suitable predictor for cognitive decline. We aimed to test associations between polypharmacy and both short-term (six months) and long-term (three years) cognitive trajectories in patients with incident dementia. Using data from a large mental health and dementia care database in South London, a cohort of 12,148 patients (mean age = 80.7 years, 61.1% female, mean MMSE = 18.6) clinically diagnosed with dementia was identified. We determined the number of medi…

Male0301 basic medicineGerontologyAgingCognitive declineBiochemistryCohort Studies03 medical and health sciencesCognitionCommunity care0302 clinical medicineEndocrinologyA large representative cohort study.- Experimental gerontology cilt.120 ss.62-67 2019 [Soysal P. Perera G. Isik A. Onder G. Petrovic M. Cherubini A. Maggi S. Shetty H. Molokhia M. Smith L. et al. -The relationship between polypharmacy and trajectories of cognitive decline in people with dementia]mental disordersGeneticsmedicineHumansDementiaCognitive DysfunctionCognitive declineassociations between polypharmacyMolecular BiologyAgedAged 80 and overPolypharmacypeople with dementia.Mini–Mental State Examinationmedicine.diagnostic_testbusiness.industryCognition; Cognitive decline; Community care; Dementia; PolypharmacyCognitionlong-term (three years)Cell BiologyMental Status and Dementia Testsmedicine.diseaseComorbidity030104 developmental biologyCohortPolypharmacyFemaleDementiabusinessshort-term (six months)030217 neurology & neurosurgeryCohort study
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Physical multimorbidity predicts the onset and persistence of anxiety: A prospective analysis of the Irish Longitudinal Study on Ageing.

2022

Background: The aims of the present study were to examine prospective associations of multimorbidity (i.e., >= 2 chronic conditions) at baseline with incident and persistent anxiety over a two-year follow-up period among Irish older adults, and to quantify the extent to which sleep, pain, and disability mediate the multimorbidity-anxiety relationship.& nbsp;Methods: Data from The Irish Longitudinal Study on Aging (TILDA) conducted between 2009 and 2011 with a follow-up after two years were analyzed. Anxiety referred to score >=& nbsp;8 on the anxiety section of the Hospital Anxiety and Depression Scale. Lifetime diagnosis of 14 chronic conditions was obtained. Outcomes were in…

MaleAgingA prospective analysis of the Irish Longitudinal Study on Ageing.- Journal of affective disorders 2022 [Smith L. Shin J. I. Jacob L. Schuch F. Pizzol D. López Sánchez G. F. Soysal P. Tully M. A. Butler L. T. Barnett Y. et al. -Physical multimorbidity predicts the onset and persistence of anxiety]MultimorbidityPainAnxietyPsychiatry and Mental healthClinical PsychologyChronic DiseaseHumansFemaleAnxiety Cohort Epidemiology Multimorbidity Older adultsLongitudinal StudiesAged
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Urinary incontinence and quality of life: a longitudinal analysis from the English Longitudinal Study of Ageing

2022

Objectives-\ud To explore the longitudinal association between urinary incontinence (UI) and quality of life (QoL) in the English Longitudinal Study on Ageing, a large study of older UK adults with ten years of follow-up.\ud Study design-\ud Cohort study.\ud Main outcomes interest-\ud To determine the presence of UI, participants reported whether they had lost urine beyond their control in the last 12 months. Participants also reported whether UI lasted more than one month, indicating a more chronic problem. QoL was measured using the CASP (control, autonomy, self-realisation and pleasure)-19, with higher values indicating a higher QoL.\ud Results-\ud Of the 8028 participants (mean age: 65.…

MaleAgingCohortObstetrics and GynecologyA longitudinal analysis from the English Longitudinal Study of Ageing- MATURITAS cilt.160 ss.11-15 2022 [Veronese N. Smith L. Pizzol D. SOYSAL P. Maggi S. Ilie P. Dominguez L. J. Barbagallo M. -Urinary incontinence and quality of life]ELSAAgeing; Cohort; ELSA; Longitudinal; Quality of life; Urinary incontinence; Aged; Aging; Cohort Studies; Female; Humans; Longitudinal Studies; Male; Surveys and Questionnaires; Quality of Life; Urinary IncontinencehumanitiesUrinary incontinence Quality of life ELSA Ageing Longitudinal CohortGeneral Biochemistry Genetics and Molecular BiologyCohort StudiesAgeingUrinary IncontinenceSurveys and QuestionnairesLongitudinalQuality of LifeHumansFemaleLongitudinal StudiesAged
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Association between food insecurity and fall-related injury among adults aged ≥65 years in low- and middle-income countries: The role of mental healt…

2021

Purpose:\ud \ud We investigated the association between food insecurity and fall-related injury among older adults from six low- and middle-income countries (LMICs), and the extent to which this association is mediated by mental health.\ud \ud Methods:\ud \ud Cross-sectional, community-based, nationally representative data from the WHO Study on global AGEing and adult health (SAGE) were analyzed. Past 12-month food insecurity was assessed with two questions on frequency of eating less and hunger due to lack of food. Fall-related injury referred to those that occurred in the past 12 months. Multivariable logistic regression analysis and mediation analysis were conducted to assess association…

MaleAgingHealth (social science)*Low- and middle-income countriesPsychological interventionLogistic regressionFood SupplyOdds03 medical and health sciencesOlder adults.0302 clinical medicineFall-related injuryEnvironmental health*Fall-related injuryPrevalenceHumansMedicine030212 general & internal medicineDeveloping CountriesDepression (differential diagnoses)Aged*Older adults2. Zero hungerLow- and middle-income countries030214 geriatricsFood insecuritybusiness.industry[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyConfoundingCognitionMESH: Accidental Falls Aged Cross-Sectional Studies Developing Countries Female Food Insecurity Food Supply Humans Male Mental Health PrevalenceMental health3. Good healthCross-Sectional StudiesMental HealthLow- and middle-income countrie*Food insecurityOlder adultsAnxietyAccidental FallsFemaleGeriatrics and Gerontologymedicine.symptombusinessGerontologyThe role of mental health conditions.- Archives of gerontology and geriatrics cilt.96 ss.104438 2021 [Smith L. Shin J. I. López-Sánchez G. F. Veronese N. Soysal P. Oh H. Grabovac I. Barnett Y. Jacob L. Koyanagi A. -Association between food insecurity and fall-related injury among adults aged ≥65 years in low- and middle-income countries]
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Sleep Quality, Duration, and Associated Sexual Function at Older Age: Findings from the English Longitudinal Study of Ageing

2019

Abstract Introduction One factor that may plausibly be associated with sexual dysfunction is sleep disturbance. Like sexual problems, complaints of sleep disturbance increase with age and are commonly reported by older adults. Aims To examine associations between sleep quality, duration, and a range of sexual problems in a large, representative sample of older adults. Methods Data were from 2,568 men and 1,376 women (age ≥50 years) participating in Wave 6 of the English Longitudinal Study of Ageing (2012–2013). Sleep quality, duration, and problems with erectile function, sexual arousal, and orgasmic experience were self-reported; associations were examined using logistic regression models.…

MaleAgingLongitudinal studySexual DysfunctionSexual BehaviorUrologyEndocrinology Diabetes and Metabolismmedia_common.quotation_subjectSexual arousal030232 urology & nephrologyOrgasmSexual Activity03 medical and health sciences0302 clinical medicineEndocrinologyErectile DysfunctionSleep ProblemmedicineHumansLongitudinal StudiesFindings from the English Longitudinal Study of Ageing.- The journal of sexual medicine cilt.16 ss.427-433 2019 [SMITH L. GRABOVAC I. VERONESE N. Soysal P. ISIK A. STUBBS B. YANG L. JACKSON S. -Sleep Quality Duration and Associated Sexual Function at Older Age]OrgasmExerciseAgedmedia_commonSleep disorder030219 obstetrics & reproductive medicineDepressionbusiness.industrySmokingSleep DurationOdds ratioMiddle Agedmedicine.diseaseSexual Dysfunction PhysiologicalPsychiatry and Mental healthCross-Sectional StudiesSexual PartnersSexual dysfunctionErectile dysfunctionReproductive MedicineFemaleSelf Reportmedicine.symptomSleepbusinessSexual functionDemography
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