Search results for "Spain"

showing 10 items of 2556 documents

Dietary therapy and non-surgical periodontal treatment in obese patients with chronic periodontitis.

2018

Aim The effect of dietary weight loss intervention on periodontal therapy is unknown. Therefore, we aimed to evaluate whether weight loss improves the response of obese subjects to non-surgical periodontal treatment. Materials and methods This interventional study in obese patients was conducted at the University Hospital Dr. Peset (Valencia, Spain). Patients were divided into two groups with and without dietary therapy. All participants received non-surgical periodontal treatment. Periodontal, anthropometric and biochemical parameters were assessed at baseline and 12 weeks. Results A total of 78 patients were re-evaluated after intervention. All periodontal parameters improved in both grou…

medicine.medical_specialtyDiet therapy030209 endocrinology & metabolismSystemic inflammationGastroenterology03 medical and health sciences0302 clinical medicineWeight lossInternal medicinePeriodontal Attachment LossWeight LossMedicineHumansObesityPeriodontitisComplement component 3business.industry030206 dentistryAnthropometrymedicine.diseaseChronic periodontitisObesitySpainChronic PeriodontitisPeriodonticsmedicine.symptomPeriodontal IndexbusinessJournal of clinical periodontology
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Air pollution exposure during pregnancy and reduced birth size: a prospective birth cohort study in Valencia, Spain

2010

Abstract Background Maternal exposure to air pollution has been related to fetal growth in a number of recent scientific studies. The objective of this study was to assess the association between exposure to air pollution during pregnancy and anthropometric measures at birth in a cohort in Valencia, Spain. Methods Seven hundred and eighty-five pregnant women and their singleton newborns participated in the study. Exposure to ambient nitrogen dioxide (NO2) was estimated by means of land use regression. NO2 spatial estimations were adjusted to correspond to relevant pregnancy periods (whole pregnancy and trimesters) for each woman. Outcome variables were birth weight, length, and head circumf…

medicine.medical_specialtyEmbarazoBirth weightHealth Toxicology and MutagenesisNitrogen Dioxidelcsh:RC963-969PregnancyEstudios prospectivosmedicine:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Air Pollutants [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Maternal Exposure [Medical Subject Headings]Birth WeightBody SizeHumansContaminantes del aireProspective StudiesProspective cohort study:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]Vehicle Emissions:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]PregnancyAir PollutantsInhalation Exposurebusiness.industryObstetricslcsh:Public aspects of medicineResearchPublic Health Environmental and Occupational HealthInfant Newbornlcsh:RA1-1270Odds ratioAnthropometrymedicine.disease:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Prospective Studies [Medical Subject Headings]Exposición maternaMaternal ExposureSpainCohortInfant Small for Gestational Agelcsh:Industrial medicine. Industrial hygieneSmall for gestational ageFemaleValenciabusinessCohort studyEnvironmental Monitoring
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Anthropometric parameters and permanent remission of comorbidities 10 years after open gastric bypass in a cohort with high prevalence of super-obesi…

2017

Abstract Background and aim Roux-en-Y gastric bypass (RYGB) is an effective treatment for weight loss in patients with morbid obesity. However, few studies have assessed its long-term efficacy in super-obese patients. The study objective was to analyse the long-term effectiveness of RYGB and its effect on improvement of comorbidities after 10 years of follow-up, and to compare the results depending on baseline BMI ( 2 vs ≥50 kg/m 2 ). Patients and methods A retrospective study was conducted in 63 patients referred for RYGB with a 10-year or longer follow-up period. Mean BMI before surgery was 55 kg/m 2 . Results Mean BMI decreased to 38.1 kg/m 2 at 10 years of follow-up. The success rates a…

medicine.medical_specialtyEndocrinology Diabetes and MetabolismGastric bypassGastric Bypass030209 endocrinology & metabolismComorbidityBody Mass Index03 medical and health sciencesPostoperative Complications0302 clinical medicineEndocrinologyWeight lossDiabetes mellitusInternal medicineWeight LossPrevalencemedicinePostoperative Period030212 general & internal medicineDyslipidemiasSleep Apnea ObstructiveNutrition and Dieteticsbusiness.industryRemission Inductionnutritional and metabolic diseasesSleep apneaRetrospective cohort studymedicine.diseaseComorbidityObesity MorbidSurgeryTreatment OutcomeDiabetes Mellitus Type 2SpainHypertensionCohortmedicine.symptombusinessDyslipidemiaFollow-Up StudiesEndocrinología, Diabetes y Nutrición
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Prevalence and comorbidity of attention deficit hyperactivity disorder in Spain: study protocol for extending a systematic review with updated meta-a…

2019

© The Author(s) 2019.

medicine.medical_specialtyEpidemiological studyPopulationMEDLINElcsh:MedicineMedicine (miscellaneous)ComorbidityPsycINFOImpulsivityAttention deficit hyperactivity disorder03 medical and health sciences0302 clinical medicineMeta-Analysis as Topicmental disordersProtocolPrevalencemedicineHumansAttention deficit hyperactivity disorder030212 general & internal medicineeducationPsychiatryeducation.field_of_studybusiness.industry030503 health policy & serviceslcsh:Rmedicine.diseaseComorbidityObservational Studies as TopicMeta-analysisCross-Sectional StudiesAttention Deficit Disorder with HyperactivityResearch DesignSpainMeta-analysisSystematic reviewObservational studymedicine.symptom0305 other medical sciencebusinessSystematic Reviews as TopicSystematic Reviews
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Evidence-based Guidelines for the Management of Exocrine Pancreatic Insufficiency After Pancreatic Surgery

2016

Objective: To provide evidence-based recommendations for the management of exocrine pancreatic insufficiency (EPI) after pancreatic surgery. Background: EPI is a common complication after pancreatic surgery but there is certain confusion about its frequency, optimal methods of diagnosis, and when and how to treat these patients. Methods: Eighteen multidisciplinary reviewers performed a systematic review on 10 predefined questions following the GRADE methodology. Six external expert referees reviewed the retrieved information. Members from Spanish Association of Pancreatology were invited to suggest modifications and voted for the quantification of agreement. Results: These guidelines analyz…

medicine.medical_specialtyEvidence-based practicediagnosisMEDLINEGuidelines030230 surgeryGastroenterologyPancreatic surgerysurgery03 medical and health sciencesPostoperative Complications0302 clinical medicineInternal medicineparasitic diseasesmedicineHumansGuidelines Management Exocrine Pancreatic Insufficiency Pancreatic SurgerypancreasguidelinesExocrine pancreatic insufficiencyPancreatic SurgeryConfusionpancreatic exocrine insufficiencyEvidence-Based Medicinetreatmentbusiness.industryPancreatic DiseasesEvidence-based medicinemedicine.diseaseManagementSurgerySpainpancreaticPractice Guidelines as TopicExocrine Pancreatic Insufficiency030211 gastroenterology & hepatologySurgerymedicine.symptomComplicationOptimal methodsbusinessAnnals of Surgery
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Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.

2010

PURPOSE. The purpose of this study was to test the ability of the genotyping microarray for Usher syndrome (USH) to identify the mutations responsible for the disease in a cohort of 183 patients with USH. METHODS. DNA from 183 patients with Usher syndrome from the Spanish population was analyzed using a genotyping microarray containing 429 previously identified disease-associated variants in eight USH genes. Mutations detected by the array were confirmed by direct sequencing. Haplotype analysis was also performed in families carrying common Spanish mutations. RESULTS. The genotyping microarray identified 43 different variants, divided into 32 disease causative and 11 probably non-pathologic…

medicine.medical_specialtyGenotypeMicroarrayUsher syndromeDNA Mutational AnalysisCadherin Related ProteinsCell Cycle ProteinsNerve Tissue ProteinsMyosinsBiologymedicine.disease_causePolymerase Chain ReactionReceptors G-Protein-CoupledMolecular geneticsGenotypemedicineotorhinolaryngologic diseasesHumansGenotypingAllelesAdaptor Proteins Signal TransducingOligonucleotide Array Sequence AnalysisGeneticsExtracellular Matrix ProteinsMutationGene Expression ProfilingHaplotypeMembrane ProteinsCadherinsmedicine.diseaseGene expression profilingCytoskeletal ProteinsSpainMyosin VIIaMutationUsher Syndromes
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Molecular Surveillance of HIV-1 in Madrid, Spain: a Phylogeographic Analysis ▿

2011

ABSTRACT The molecular epidemiology of HIV-1 is constantly changing, mainly as a result of human migratory flows and the high adaptive ability of the virus. In recent years, Spain has become one of Europe's main destinations for immigrants and one of the western European countries with the highest rates of HIV-positive patients. Using a phylogeographic approach, we have analyzed the relationship between HIV-1 variants detected in immigrant and native populations of the urban area of Madrid. Our project was based on two coincidental facts. First, resistance tests were extended to naïve and newly diagnosed patients, and second, the Spanish government legislated the provision of legal status t…

medicine.medical_specialtyGenotypemedia_common.quotation_subjectImmunologyImmigrationMolecular Sequence DataHuman immunodeficiency virus (HIV)HIV InfectionsBiologyDestinationsmedicine.disease_causeMicrobiologylaw.invention03 medical and health sciences0302 clinical medicinePopulation GroupslawVirologyEpidemiologymedicinePrevalenceCluster AnalysisHumans030212 general & internal medicine030304 developmental biologymedia_commonTransients and Migrants0303 health sciencesMolecular EpidemiologyMolecular epidemiologySequence Analysis DNA3. Good healthPhylogeographyPhylogeographyTransmission (mechanics)Genetic Diversity and EvolutionSpainpol Gene Products Human Immunodeficiency VirusInsect ScienceCohortHIV-1Demography
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Sequential evolution of genotype GII.4 norovirus variants causing gastroenteritis outbreaks from 2001 to 2006 in Eastern Spain.

2008

Noroviruses are the most common cause of outbreaks of viral gastroenteritis worldwide. Norovirus outbreaks were surveyed in Catalonia and the region of Valencia (Eastern Spain) between January 2001 and December 2006 as part of the European Union funded network "Food-borne viruses in Europe". During this time the etiology and epidemiological features of 194 outbreaks of acute non-bacterial gastroenteritis were investigated and norovirus was identified as causing 169 (87.1%) of them. Molecular epidemiology of viral strains was studied by RT-PCR and sequencing part of the RNA polymerase gene in ORF1 from 153 outbreak strains. The most commonly identified norovirus genotype was GII.4 (71.9% of …

medicine.medical_specialtyGenotypevirusesBiologymedicine.disease_causeMicrobiologyDisease OutbreaksEvolution MolecularFecesfluids and secretionsVirologyGenotypeGenetic variationEpidemiologymedicinemedia_common.cataloged_instanceHumansEuropean unionPhylogenymedia_commonCaliciviridae InfectionsMolecular epidemiologyNorovirusvirus diseasesOutbreakGenetic VariationVirologyGastroenteritisInfectious DiseasesSpainNorovirusEtiologySeasonsJournal of medical virology
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Determinants of Knowledge of Pain among Nurses in a Tertiary Hospital in Spain.

2020

Poorly controlled pain in patients is related to several complications, such as increased nosocomial infections and mortality, where nurses play a crucial role.To analyze determinants of pain as well as nurses' knowledge and attitudes towards pain in the inpatient services of a tertiary center in the Spanish public health network.The Knowledge and Attitudes Survey Regarding Pain questionnaire was administered to all nurses in the center from January to March 2019. Additional sociodemographic variables, such as gender, age, employment status, work experience, professional group, and academic degree, were collected and analyzed. Item Response Theory was used for discriminant analysis of each …

medicine.medical_specialtyHealth Knowledge Attitudes PracticeAttitude of Health PersonnelMEDLINENursesPainNursing Staff HospitalTertiary Care Centers03 medical and health sciences0302 clinical medicineIntensive careSurveys and QuestionnairesItem response theorymedicineHumansIn patient030212 general & internal medicineAdvanced and Specialized Nursing030504 nursingbusiness.industryPublic healthControlled painWork experienceSpainFamily medicineClinical Competence0305 other medical sciencebusinessProfessional groupPain management nursing : official journal of the American Society of Pain Management Nurses
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Effects of lindane on fish carbohydrate metabolism.

1991

Exposure of the European eel (Anguilla anguilla) to a high sublethal concentration of 0.335 ppm (0.50 of the 96-hr LC50) of lindane for 6, 12, 24, 48, 72, and 96 hr affected carbohydrate metabolism. Muscle glycogen levels decreased significantly (P less than 0.05) at 6, 12, 24, 48, 72, and 96 hr; liver glycogen content did not decline at any time. Muscle glucose levels in fish were elevated at 6, 12, 24, 48, 72, and 96 hr but in liver, the levels increased only at 96 hr. Mean values of muscle and liver pyruvate were elevated significantly (P less than 0.05) at 6, 12, 24, 48, and 72 hr. Muscle lactate levels increased at 6, 12, 24, and 48 hr in pesticide-treated fish. Liver lactate levels we…

medicine.medical_specialtyHealth Toxicology and MutagenesisCarbohydrate metabolismBiologychemistry.chemical_compoundInternal medicinemedicineAnimalsGlycogenMusclesPublic Health Environmental and Occupational HealthGeneral MedicinePesticideCarbohydrateAnguillaPollutionEndocrinologychemistryLiverSpainToxicityFish <Actinopterygii>Carbohydrate MetabolismPyruvic acidLindaneHexachlorocyclohexaneEcotoxicology and environmental safety
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