Search results for "Spain"

showing 10 items of 2556 documents

Professional stakeholders' views of the use of digital technologies in Spanish long-term care

2018

Demographic change in Europe has resulted in an aging population, which presents new challenges for implementing and managing long-term care (LTC) systems. One solution aims to increase the efficiency of LTC by using digital technologies. This article focuses on professionals’ opinions of the use of digital technologies in the administration of Spain’s long-term care law (Law 39/2006, December 14, LAPAD). This qualitative research is part of SoCaTel, an H2020 project on the co-creation of LTC services in Europe. Ten focus groups were held with health professionals, care-taking relatives, and care workers, and six semistructured in-depth interviews were conducted with care recipients in Cata…

0209 industrial biotechnologySocial PsychologySocial Welfare02 engineering and technologydigitalizationLAPADsocial services020901 industrial engineering & automation0502 economics and businessdigital technologieslcsh:T58.5-58.64lcsh:Information technologybusiness.industryCommunication05 social sciencesPublic relationsHuman-Computer InteractionLong-term careSpainInformation and Communications TechnologyICTLTClong-term careBusiness050203 business & managementHuman Technology
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Urban upbringing and childhood respiratory and allergic conditions: A multi-country holistic study

2018

Objective: We integratively assessed the effect of different indoor and outdoor environmental exposures early in life on respiratory and allergic health conditions among children from (sub-) urban areas. Methods: This study included children participating in four ongoing European birth cohorts located in three different geographical regions: INMA (Spain), LISAplus (Germany), GINIplus (Germany) and BAMSE (Sweden). Wheezing, bronchitis, asthma and allergic rhinitis throughout childhood were assessed using parental-completed questionnaires. We designed “environmental scores” corresponding to different indoor, green- and grey-related exposures (main analysis, a-priori-approach). Cohort-specific…

0301 basic medicine05 Environmental SciencesIndoor exposureFirst year of lifeMicrobial loadToxicologyBiochemistryGrey spaceAllergic rhinitis03 medical and health sciences0302 clinical medicineGermanyEnvironmental healthmedicineHumansRespiratory systemChildRespiratory SoundsGeneral Environmental ScienceAsthmaSwedenGreen space2. Zero hungerbusiness.industryEnvironmental ExposureOdds ratio06 Biological Sciencesmedicine.diseaseRhinitis AllergicAsthmaConfidence intervalConfirmatory factor analysis3. Good health030104 developmental biology030228 respiratory systemSpainBronchitisEnvironmental Pollutants03 Chemical SciencesbusinessAllergic Rhinitis ; Asthma ; Green Space ; Grey Space ; Indoor Exposure ; Microbial LoadMulti countryEnvironmental Research
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Nutritional assessment of the school menus offered in Spain's Mediterranean area.

2019

Abstract Objectives The aim of this study was to perform a nutritional assessment of the menus served in school canteens and to verify their effects on the nutrition of schoolchildren. Methods We selected three collective catering companies that offered ~53 500 menus/d in 369 schools in Spain's Mediterranean area (Valencian Community). The study included four public schools with different management models as well as different supply patterns. Considering the weight of the servings, the caloric contribution of the menus was estimated. Results Great diversity was seen both in the same school throughout the week and between the four schools (School 1: 298–946 kcal; School 2: 465–1185 kcal; Sc…

0301 basic medicine2019-20 coronavirus outbreak030109 nutrition & dieteticsNutrition and DieteticsSchoolsCoronavirus disease 2019 (COVID-19)Salt contentEndocrinology Diabetes and MetabolismNutritional compositionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Food Services030209 endocrinology & metabolismValencian community03 medical and health sciences0302 clinical medicineGeographyNutrition AssessmentSpainEnvironmental healthMediterranean areaHumansProcessed meatChildEnergy IntakeNutrition (Burbank, Los Angeles County, Calif.)
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Autosomal recessive hypercholesterolemia in Spain.

2017

Abstract Background and aims Autosomal recessive hypercholesterolemia (ARH) is a very rare disease, caused by mutations in LDL protein receptor adaptor 1 (LDLRAP1). It is characterized by high levels of low-density lipoprotein cholesterol (LDL-C) and increased risk of premature cardiovascular disease. We aimed to characterize ARH in Spain. Methods Data were collected from the Dyslipidemia Registry of the Spanish Atherosclerosis Society. A literature search was performed up to June 2017, and all diagnostic genetic studies for familial hypercholesterolemia of Spain were reviewed. Results Seven patients with ARH were identified, 6 true homozygous and one compound heterozygous with a novel muta…

0301 basic medicineAdultGenetic MarkersMalemedicine.medical_specialtyHeterozygoteHypercholesterolemiaDiseaseFamilial hypercholesterolemia030204 cardiovascular system & hematologyCompound heterozygosity03 medical and health sciences0302 clinical medicineInternal medicinemedicinePrevalenceHumansGenetic Predisposition to DiseaseRegistriesChildAdaptor Proteins Signal TransducingHypolipidemic Agentsbusiness.industryGenetic heterogeneityHomozygoteInfantCholesterol LDLMiddle Agedmedicine.diseaseAtherosclerosisUp-Regulation030104 developmental biologyEndocrinologyPhenotypeAutosomal Recessive HypercholesterolemiaSpainChild PreschoolCohortMutationDisease ProgressionFemaleCardiology and Cardiovascular MedicinebusinessDyslipidemiaRare diseaseAtherosclerosis
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Occupational Heat Exposure and Breast Cancer Risk in the MCC-Spain Study.

2021

Background: Mechanisms linking occupational heat exposure with chronic diseases have been proposed. However, evidence on occupational heat exposure and cancer risk is limited. Methods: We evaluated occupational heat exposure and female breast cancer risk in a large Spanish case-control study. We enrolled 1,738 breast cancer cases and 1,910 frequency-matched population controls. A Spanish job exposure matrix, MatEmEsp, was used to assign estimates of the proportion of workers exposed (P greater than or equal to 25% for at least one year) and work time with heat stress (wet bulb globe temperature ISO 7243) for each occupation. We used three exposure indices: ever vs. never exposed, lifetime c…

0301 basic medicineAdultHot TemperatureEpidemiologyPopulationJob-exposure matrixCumulative ExposureBreast NeoplasmsDisease03 medical and health sciences0302 clinical medicineBreast cancerRisk FactorsEnvironmental healthOccupational ExposureMedicineHumanseducationAgedAged 80 and overeducation.field_of_studybusiness.industryConfoundingOdds ratioMiddle Agedmedicine.diseaseConfidence intervalOccupational Diseases030104 developmental biologyOncologySpain030220 oncology & carcinogenesisCase-Control StudiesFemalebusiness
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Measuring Orthorexia Nervosa: Psychometric Limitations of the ORTO-15.

2017

AbstractOrthorexia nervosa has recently been defined as excessive preoccupation with healthy eating, causing significant nutritional deficiencies and social and personal impairments. The ORTO-15 is the most widely used instrument to evaluate orthorexia nervosa, although previous studies obtained inconsistent results about its psychometric properties, and there are no data on the Spanish version. Thus, the main objective of the present study was to analyze the psychometric properties of the Spanish adaptation of the ORTO-15. In order to cross-validate the results, two independent samples were used (Sample 1: n = 807, 74.1% women; Sample 2: n = 242, 63.2% women). The results did not support t…

0301 basic medicineAdultMale050103 clinical psychologyLinguistics and LanguagePsychometricsHealth BehaviorHealthy eatingLanguage and LinguisticsDevelopmental psychologyFeeding and Eating Disorders03 medical and health sciencesYoung AdultInternal consistencyIndependent samplesmedicineHumans0501 psychology and cognitive sciencesGeneral PsychologyOrthorexia nervosaPsychiatric Status Rating Scales030109 nutrition & dietetics05 social sciencesReproducibility of ResultsSpanish versionmedicine.diseaseSpainFemalePsychologyPsychopathologyThe Spanish journal of psychology
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Coffee consumption and total mortality in a Mediterranean prospective cohort

2018

Background The relation of coffee consumption with total mortality is controversial, because the available evidence is still inconsistent. Objective This study aimed to assess this association in a highly educated, middle-aged Mediterranean cohort. Design We analyzed data from 201,055 person-years of follow-up arising from 19,888 participants. Coffee consumption was obtained at baseline with the use of a previously validated semiquantitative food-frequency questionnaire. Information on mortality was ascertained by permanent contact with the "Seguimiento Universidad de Navarra" (SUN) participants and their families, postal authorities, and consultation of the National Death Index. We used Co…

0301 basic medicineAdultMaleCaffeine; Coffee; Mediterranean diet; Polyphenols; Total mortality; Medicine (miscellaneous); Nutrition and DieteticsMediterranean dietUniversitiesMedicine (miscellaneous)Lower riskDiet MediterraneanNational Death IndexDiet SurveysCoffee03 medical and health sciences0302 clinical medicineRisk FactorsCause of DeathCaffeineMediterranean dietMedicineHumans030212 general & internal medicineProspective StudiesProspective cohort studyCause of deathProportional Hazards Models030109 nutrition & dieteticsNutrition and DieteticsTotal mortalityProportional hazards modelbusiness.industryMediterranean RegionConfoundingAge FactorsPolyphenolsFeeding BehaviorMiddle AgedDietSpainCohortEducational StatusFemalebusinessDemographyFollow-Up Studies
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Genetics of Wilson disease and Wilson-like phenotype in a clinical series from eastern Spain.

2019

Wilson's disease (WD) is an autosomal recessive disorder caused by ATP7B mutations. Subjects with only one mutation may show clinical signs and individuals with biallelic changes may remain asymptomatic. We aimed to achieve a conclusive genetic diagnosis for 34 patients clinically diagnosed of WD. Genetic analysis comprised from analysis of exons to WES (whole exome sequencing), including promoter, introns, UTRs (untranslated regions), besides of study of large deletions/duplications by MLPA (multiplex ligation-dependent probe amplification). Biallelic ATP7B mutations were identified in 30 patients, so that four patients were analyzed using WES. Two affected siblings resulted to be compound…

0301 basic medicineAdultMaleNerve Tissue Proteins030105 genetics & heredityBiologymedicine.disease_causeCompound heterozygosityGenetic analysis03 medical and health sciencesExonHepatolenticular DegenerationExome SequencingGeneticsmedicineHumansGenetic Predisposition to DiseaseMultiplex ligation-dependent probe amplificationGenetic TestingGenetics (clinical)Exome sequencingGeneticsMutationExonsmedicine.diseaseWilson's disease030104 developmental biologyPhenotypeCopper-Transporting ATPasesSpainMutationFemaleCongenital disorder of glycosylationClinical geneticsREFERENCES
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Characterisation of a household norovirus outbreak occurred in Valencia (Spain)

2016

Background Human noroviruses (NoVs) are the main cause of non-bacterial gastroenteritis worldwide. Several studies have linked human susceptibility to NoVs with the expression of histo-blood group antigens (HBGAs). In January 2012, a NoV gastroenteritis outbreak affected a household in Valencia, Spain, and the personal susceptibility to NoV was investigated. Methods To reach this aim 8 members of the affected household were recruited for this study and their secretor status, ABO and Lewis antigens were determined. NoV-specific saliva IgA and serum IgG antibody titers were analyzed. Their capacity to block viral binding to saliva receptors was analyzed, using virus-like particles (VLPs) of t…

0301 basic medicineAdultMaleSalivaGenotypeIgGFUT2030106 microbiologyHisto-blood group antigensBiologymedicine.disease_causeDisease Outbreaks03 medical and health sciencesSecretorFecesfluids and secretionsstomatognathic systemABO blood group systemGenotypemedicineHumansChildSalivaCaliciviridae InfectionsBlood typeBinding assayFamily CharacteristicsNorovirusAntibody titerOutbreakVirus-like particlesMiddle AgedVirologyGastroenteritis030104 developmental biologyInfectious DiseasesSusceptibilitySpainImmunologybiology.proteinNorovirusFemaleAntibodyIgAResearch ArticleBMC Infectious Diseases
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Temporal association between the influenza virus and respiratory syncytial virus (RSV): RSV as a predictor of seasonal influenza.

2016

SUMMARYEpidemiologists agree that there is a prevailing seasonality in the presentation of epidemic waves of respiratory syncytial virus (RSV) infections and influenza. The aim of this study is to quantify the potential relationship between the activity of RSV, with respect to the influenza virus, in order to use the RSV seasonal curve as a predictor of the evolution of an influenza virus epidemic wave. Two statistical tools, logistic regression and time series, are used for predicting the evolution of influenza. Both logistic models and time series of influenza consider RSV information from previous weeks. Data consist of influenza and confirmed RSV cases reported in Comunitat Valenciana (…

0301 basic medicineAdultMaleTime FactorsMultinomial logistic modelAdolescentEpidemiologyBinomial regression030106 microbiologyRespiratory Syncytial Virus InfectionsBiologyLogistic regressionmedicine.disease_causeVirusSeasonal influenza03 medical and health sciencesYoung AdultInfluenza HumanmedicineHumansChildEpidemicsAgedAged 80 and overInfant Newbornvirus diseasesInfantMiddle AgedOrthomyxoviridaeVirologyOriginal PapersInfectious DiseasesRespiratory syncytial virus (RSV)Logistic ModelsSpainChild PreschoolRespiratory Syncytial Virus HumanFemaleSeasonsEpidemiology and infection
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