Search results for "Spermatocyte"

showing 9 items of 19 documents

Organometallic complexes with biological molecules. XVII. Triorganotin(IV) complexes with amoxicillin and ampicillin.

2002

Novel triorganotin(IV) complexes of two β-lactamic antibiotics, 6-[D-(-)-β-amino-p-hydroxyphenyl-acetamido]penicillin (=amoxicillin) and 6-[D-(-)-α-aminobenzyl]penicillin (=ampicillin), have been synthesized and investigated both in solid and solution states. The complexes corresponded to the general formula R3Sn(IV)antib·H2O (R=Me, n-Bu, Ph; antib=amox=amoxicillinate or amp=ampicillinate). Structural investigations about configuration in the solid state have been carried out by interpreting experimental IR and 119Sn Mössbauer data. In particular, IR results suggested polymeric structures both for R3Sn(IV)amox·H2O and R3Sn(IV)amp·H2O. Moreover, both antibiotics appear to behave as monoanion…

MaleMagnetic Resonance SpectroscopySpectrophotometry InfraredOrganotin(IV) complexeAmoxicillinPenicillinBiochemistryBiological moleculeChromosomesBivalviaInorganic ChemistrySolutionsStructure-Activity RelationshipSettore CHIM/03 - Chimica Generale E InorganicaSpermatocytesThermogravimetryOrganotin CompoundsAnimalsAmpicillinDNA DamageJournal of inorganic biochemistry
researchProduct

Virus-like particles, bacteria and microsporidia affect spindle-associated membranes in spermatocytes of Lepidoptera species.

1997

SummaryLarval testes of four Lepidoptera species were examined using electron microscopy. The testes of one species, the Mediterranean mealmothEphestia kuehniella(Pyralidae), were devoid of intracellular pathogens and serve as a control. In this species, metaphase spindles of primary spermatocytes showed a thick layer of perispindle membranes. The membranes were structurally very similar to the agranular endoplasmic reticulum. Membranes of this type occurred also at high frequency throughout the spindle matrix. The analysis of larval testes ofPieris brassicae(Pieridae) revealed virus-like particles within spermatocytes. In another species,Philudoria potatoria(Lasiocampidae), the spermatocyt…

MalePieris brassicaebiologyBacteriaMicrosporidaVirionCell BiologySpindle matrixIntracellular MembranesSpindle ApparatusMothsbiology.organism_classificationCell biologyLepidoptera genitaliaMicroscopy ElectronMembraneMeiosisSpermatocytesMicrosporidiaBotanyTestisAnimalsSpermatogenesisMetaphaseDevelopmental BiologyZygote (Cambridge, England)
researchProduct

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination

2015

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM

MaleProgrammed cell deathMicrocephalyGeneral Physics and AstronomyCell Cycle ProteinsDwarfismBiologyReal-Time Polymerase Chain ReactionArticleGeneral Biochemistry Genetics and Molecular BiologyMice03 medical and health sciences0302 clinical medicineChromosome structureSpermatocytesmedicineAnimalscentrioleHomologous Recombination030304 developmental biologyRecombination GeneticfertilityGeneticsCentrosomeMeiotic recombination0303 health sciencesMultidisciplinarySperm CountProtein cep63FaciesGeneral Chemistrymedicine.diseaseBiología y Biomedicina / BiologíaImmunohistochemistryNeural stem cell3. Good healthCEP63MeiosisSeckel syndromeCentrosomeMicrocephalyTumor Suppressor Protein p53Homologous recombinationmicrocephaly ; DNA damage ; centrosome ; meiosis030217 neurology & neurosurgeryDNA Damage
researchProduct

Repetitive DNAs in the slug Milax nigricans: association of ribosomal (18S–28S and 5S rDNA) and (TTAGGG)n telomeric sequences) in the slug M. nigrica…

2003

Spermatocyte chromosomes of the slug Milax nigricans (Mollusca: Gastropoda: Pulmonata) were studied using silver staining (Ag-NOR) and fluorescent in situ hybridization (FISH) with four repetitive DNA probes [18S rDNA, 5S rDNA, (TTAGGG)n and (GATA)n]. Silver impregnation was inadequate to localize the chromosome sites of nucleolus organizer regions (NORs) since no silver dots occurred on the chromosomes at spermatogonial metaphase and a diffuse silver stainability could be observed on the bivalents at metaphase-I. Unlike silver staining, single-colour rDNA FISH consistently mapped major ribosomal sites (18S-28S rDNA) on two small-sized chromosomes in spermatogonial cells and on the correspo…

MaleSilverNucleolusGeneral Physics and AstronomyBiologyDNA RibosomalBivalent (genetics)Silver stainSpermatocytesStructural BiologyRNA Ribosomal 28SNucleolus Organizer RegionRNA Ribosomal 18SAnimalsGeneral Materials ScienceRepeated sequenceMetaphaseIn Situ Hybridization FluorescenceRepetitive Sequences Nucleic AcidGeneticsBase SequenceStaining and LabelingRNA Ribosomal 5SChromosomeDNACell BiologyTelomereRibosomal RNAMolecular biologyMolluscaNucleolus organizer regionMicron
researchProduct

Organometallic complexes with biological molecules. XVIII. Alkyltin(IV) cephalexinate complexes: synthesis, solid state and solution phase investigat…

2004

Abstract Dialkyltin(IV) and trialkyltin(IV) complexes of the deacetoxycephalo-sporin-antibiotic cephalexin [7-( d -2-amino-2-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid] (Hceph) have been synthesized and investigated both in solid and solution phase. Analytical and thermogravimetric data supported the general formula Alk 2 SnOHceph · H 2 O and Alk 3 Snceph · H 2 O (Alk=Me, n -Bu), while structural information has been gained by FT-IR, 119 Sn Mossbauer and 1 H, 13 C, 119 Sn NMR data. In particular, IR results suggested polymeric structures both for Alk 2 SnOHceph · H 2 O and Alk 3 Snceph · H 2 O. Moreover, cephalexin appears to behave as monoanionic tridentate ligand coordinating th…

MaleThermogravimetric analysisDenticitySpectrophotometry InfraredStereochemistryMolecular Conformationchemistry.chemical_elementorganotin(IV)proton nuclear magnetic resonanceBiochemistryMedicinal chemistryChromosomesMossbauerInorganic ChemistrySpectroscopy Mossbauerchemistry.chemical_compoundantibiotic; cephalexin; organotin(IV); Mossbauer; cytotoxicitySpermatocytescomplex formationantibioticMössbauer spectroscopyOrganotin CompoundsAnimaliaAnimalsMoietyBrachidontes pharaoniCarboxylateNuclear Magnetic Resonance BiomolecularCephalexinMolecular StructureChemistryarticlesolid stateNuclear magnetic resonance spectroscopycarbon nuclear magnetic resonanceBivalviaAnti-Bacterial AgentsspermatocyteSettore CHIM/03 - Chimica Generale E InorganicaMolluscaThermogravimetryMössbauercytotoxicitycefalexinorganometallic compoundChromosome breakagedrug synthesiTinMutagensJournal of Inorganic Biochemistry
researchProduct

The murine nuclear orphan receptor GCNF is expressed in the XY body of primary spermatocytes

1998

AbstractWe have studied the expression of the nuclear orphan receptor GCNF (germ cell nuclear factor) on the mRNA and protein level in pubertal and adult mouse testes. We show by Northern and Western blot analyses and by in situ hybridization that GCNF is expressed in spermatocytes and round spermatids of adult mouse testis suggesting that GCNF may be a transcriptional regulator of spermatogenesis. Since the GCNF protein is accumulated in the XY body of late pachytene spermatocytes, it may be involved in transcriptional inactivation of sex chromosomes.

MaleTranscription GeneticGerm cell nuclear factorBiophysicsFluorescent Antibody TechniqueReceptors Cytoplasmic and NuclearIn situ hybridizationBiologyIn Vitro TechniquesGerm cell nuclear factorBiochemistryEpitheliumMiceWestern blotStructural BiologySpermatocytesNuclear Receptor Subfamily 6 Group A Member 1TestisGeneticsTranscriptional regulationmedicineAnimalsRNA MessengerRetinoid receptor-related testis-associated receptorSpermatogenesisMolecular BiologyOrphan receptorMessenger RNAMice Inbred BALB Cmedicine.diagnostic_testCell BiologyMolecular biologySpermatidsNeuron-derived orphan receptor 1DNA-Binding ProteinsGene Expression RegulationNuclear orphan receptorSpermatogenesisNeuronal cell nuclear factorXY bodyFEBS Letters
researchProduct

Spermatocyte chromosome analysis of Helicella virgata (Pulmonata: Helicidae): silver-stained and C-banded chromosomes.

1991

Chromosome numbers of the snail Helicella virgata from the fields of Castellammare del Golfo (Sicily) are n = 26 and 2n = 52. Silver-staining analyses of testicular cells suggest that both mitotic and meiotic chromosomes are involved in nucleolus organization. A within-individual variability in NOR-banding pattern is present in each of the 20 specimens analyzed.

Malemedicine.medical_specialtySnailsMitosisChromosomesHelicidaeMeiosisSpermatocytesOxazinesGeneticsmedicineAnimalsSpermatogenesisMolecular BiologyGenetics (clinical)GeneticsbiologyStaining and LabelingCytogeneticsChromosomeKaryotypeNucleolus organizationbiology.organism_classificationMolecular biologyChromosome BandingMeiosisKaryotypingHelicellaNucleolus organizer regionBiotechnologyThe Journal of heredity
researchProduct

Nucleoside uptake in male germ cells of the polychaeteNereis virens

1997

Summary Uptake of inosine and guanosine was measured in male germ ceils of the polychaete Nereis virens at different stages of development. In spermatogonia I (spg I) and spermatid stages, total inosine uptake at 12°C and ambient concentrations of 100 μmol/1 was relatively low (10–50 nmol·ml of packed cell volume pcv−l·h−1). A rapid increase (150–300 nmol·ml of pcv-1·h−1) was found during transition from spg I to spg II with a subsequent decline to low values (10–30 nmol·ml of pcv−1·h−1) in spermatocyte and spermatid stages. This transient increase may be related to the proliferative activity of spg I stages leading to spg II stages, which increases the demand of purine precursors for nucle…

PurineTransition (genetics)SpermatidGuanosineSpermatocyteBiologyMolecular biologychemistry.chemical_compoundmedicine.anatomical_structurechemistryBiochemistrymedicineNucleic acidAnimal Science and ZoologyInosineNucleosideDevelopmental Biologymedicine.drugInvertebrate Reproduction & Development
researchProduct

Spermatocyte chromosome alterations intruncatella subcylindrica (L., 1767) (Mollusca, Mesogastropoda) following exposure to dibutyltin(IV) and tribut…

1992

In order to analyze chromosomes for possible numerical and structural alterations in response to exposure to organotin(IV) compounds, gastropod Truncatella subcylindrica specimens were treated with dibutyltin(IV) and tributyltin(IV) chloride solutions with different exposure times. Experimental evidence suggests that tributyltin(IV) chloride is more toxic to this organism than dibutyltin(IV) dichloride at low concentrations. Furthermore, the toxicity responses to these organotin(IV) derivatives seem to be proportional to both concentration and exposure time. The following structural lesions have been identified by comparative analysis of spermatocyte chromosomes from untreated specimens and…

biologyStereochemistryGeneral ChemistrySpermatocytebiology.organism_classificationChlorideStainingInorganic Chemistrychemistry.chemical_compoundmedicine.anatomical_structurechemistryToxicitymedicineTributyltinColchicineMesogastropodaOrceinNuclear chemistrymedicine.drugApplied Organometallic Chemistry
researchProduct