Search results for "Spinal"
showing 10 items of 906 documents
Calcitonin gene related peptide gene expression in collagen-induced arthritis
1995
On a evalue par hybridation in situ semi-quantitative les variations de l'expression genique du peptide lie au gene de la calcitonine (CGRP) dans les motoneurones spinaux et dans les ganglions des racines dorsales (GRD) de rats chez lesquels l'arthrite a ete induite par l'administration de collagene II (AIC). On a examine les effets d'un traitement systemique avec le corticosteroide budesonide sur l'expression basale du CGRP ainsi que sur ses variations dans des conditions d'inflammation. Dans les GRD, l'AIC a induit une augmentation significative des taux d'ARNm du CGRP. Le budesonide a reduit les taux d'ARNm du CGRP constitutif de ces GRD comparativement a ceux des rats temoins non traite…
How a Fish’s Brain May Move a Fish’s Body
1990
The brainstem of the electric fish Eigenmannia virescens contains a small number of neural networks projecting directly onto the motoneuron pools of the spinal cord such that each segment is reached by at least one neuron of all the networks. Quantitative data of movement patterns, recorded from freely moving animals as well as elicited by electrical stimulation of the single networks, suggest that each network contains a full program for a particular movement, e. g. bending of the body axis to one side. By virtue of the structural relationship the programs are executable with a small number of segments. Mixing of small pieces of programs along the body axis allows for a far larger variety …
Defective carbohydrate metabolism in multiple sclerosis
2015
La esclerosis múltiple (EM) es una enfermedad crónica del sistema nervioso central (SNC) en el que episodios repetidos de inflamación (bortes), dan lugar a inflamación que conduce a la interrupción de la vaina de mielina por daños producidos en la misma. Junto a este fenómeno de inflación focal, existe una inflamación difusa en el SNC, que unida a la anterior, dará lugar a que aparezca un proceso de neurodegeneración, que será el responsable último de la afectación axonal y neuronal difusa que es la que va a condicionar la discapacidad en los pacientes afectos de EM. La enfermedad es una causa importante de discapacidad neurológica y de disfunción neurológica en adultos jóvenes que afecta a…
Acute effects of static and dynamic stretching on the neuromuscular system
2019
Stretching is traditionally incorporated into pre-exercise routines in health, rehabilitation and sporting environments to condition the neuromuscular system for exercise. While a large body of evidence reported that stretching may acutely impair the subsequent muscular performance, some conflicting results highlight possible mitigating factors of neuromuscular responses variability. Because the limited data available do not present a clear consensus, the aim of this thesis was to investigate the effects of different factors on neuromuscular responses to stretch: the muscle group, the stretch duration and modality. By means of four studies, it has been shown that static stretching may alter…
What effect can manual therapy have on a patient's pain experience?
2015
Manual therapy (MT) is a passive, skilled movement applied by clinicians that directly or indirectly targets a variety of anatomical structures or systems, which is utilized with the intent to create beneficial changes in some aspect of the patient pain experience. Collectively, the process of MT is grounded on clinical reasoning to enhance patient management for musculoskeletal pain by influencing factors from a multidimensional perspective that have potential to positively impact clinical outcomes. The influence of biomechanical, neurophysiological, psychological and nonspecific patient factors as treatment mediators and/or moderators provides additional information related to the proces…
The effect of experimental and clinical musculoskeletal pain on spinal and supraspinal projections to motoneurons and motor unit properties in humans…
2021
Background and Objective Numerous studies have examined the influence of pain on spinal reflex excitability, motor unit behaviour and corticospinal excitability. Nevertheless, there are inconsistencies in the conclusions made. This systematic review sought to understand the effect of pain on spinal and supraspinal projections to motoneurons and motor unit properties by examining the influence of clinical or experimental pain on the following three domains: H-reflex, corticospinal excitability and motor unit properties. Databases and Data Treatment MeSH terms and preselected keywords relating to the H-reflex, motor evoked potentials and motor unit decomposition in chronic and experimental pa…
Shortness of filum terminale represents an anatomical specific feature in fibromyalgia: a nuclear magnetic resonance and clinical study
2015
Background we aimed to assess whether shortness of filum terminale (FT) can represent a specific feature of fibromyalgia. Therefore we investigated benefits coming from FT section with a mini-invasive technique in patients with fibromyalgia. Filum terminale disease (FD), described firstly in 1996, is consequence of an abnormal traction exerted on spinal cord since FT is shorter than usual. Fibromyalgia syndrome (FS) is featured by chronic widespread musculoskeletal pain associated with stiffness and extra-skeletal symptoms affecting many organs and systems. Filum terminale disease and fibromyalgia syndrome share common clinical features in at least one subset of patients. Methods we evaluat…
Presacral Myelolipoma
2014
Many reports have described adrenal myelolipomas but there have been only a few reports of extra-adrenal myelolipomas. We describe a 74-year-old woman who came to our observation for MRI of the lumbar spine for typical lumbar back pain. In addition to signs of mild scoliosis and spondylo disc arthrosis, MR imaging revealed a presacral mass showing a heterogeneously high signal in all pulse sequences and almost completely suppressed on inversion recovery sequences for fat tissue. CT imaging confirmed the fatty nature of the lesion and no signs of bone involvement. These findings were most consistent with a diagnosis of a rare presacral myelolipoma as confirmed at histopathologic analysis. T…
Effectiveness of Physical Therapy in Patients with Tension-type Headache: Literature Review
2014
Background: Tension-type headache (TTH) is a disease with a great incidence on quality of life and with a significant socioeconomic impact. Objectives: The aim of this review is to determine the effectiveness of physical therapy by using manual therapy (MT) for the relief of TTH. Data sources: A review was done identifying randomized controlled trials through searches in MEDLINE, PEDro, Cochrane and CINAHL (January 2002 – April 2012). Study selection: English-language studies, with adult patients and number of subjects not under 11, diagnosed with episodic tension-type headache (ETTH) and chronic tension-type headache (CTTH) were included. Data extraction: Initial search was undertaken with…
NECK DISSECTIONS: MISCONCEPTIONS, MALPRACTICE AND COMMON CONTROVERSIES
2007
B a c k g ro u n d. Neck metastases are the single most important prognostic factor in Head and Neck Squamous Cell Carcinoma. Wise approach to neck treatment is then mandatory to give a chanche for cure. Still, there are some issues about neck dissection that need to be clarified. M e t h o d s. Through a review of the literature and of everyday clinical observations, the following issues are discussed: Functional Neck Dissection, biopsies, nodal levels, Selective Neck Dissections, Spinal Accessory Nerve, neck dissection classification. R e s u l t s. Integration of historical, anatomical, clinical and surgical concepts and up-to-date knowledge can allow to understand how to behave in diver…