Search results for "Spinal"

LE DISRAFIE SPINALI CISTICHE: casistica e attuali orientamenti terapeutici in età neonatale

1990

Gli Autori riportano la loro esperienza sul trattamento delle disrafie spinali cistiche in età neonatale e, dopo una revisione della letteratura, ne sottolineano gli aspetti deontologici, clinici e terapeutici

[Letter to the Editor] Bipolar radiofrequency ablation for metastatic spinal tumors: an evolving paradigm in palliative care

2015

I read with great interest the article by Wallace and col- laborators focusing on the combination of radiofrequency ablation (RFA) and vertebral augmentation for palliation of painful spinal metastases [1]. In a retrospective approach the authors reviewed a group of patients who underwent RFA for vertebral metastases in a period spanning almost 2 years. In a cohort of 110 patients, 72 RFA procedures were performed. Interestingly, 81 % of the metastatic lesions involved the posterior vertebral body and 45 % the pedicles. In almost all the cases, vertebral augmentation was performed following the ablation procedure.

Spinal cord compression in HIV infection

2007

Emergency Surgery ina a patient with large spontaneous epidurl hematoma determinig exellent neurological recovery: review of the literature

2014

Study Design: Case report Objectives: we report a case of a 75-year-old woman suffering voluminous idiopathic spontaneous spinal epidural hematomas (SSEH) that was rapidly diagnosed and successfully treated Methods: Clinical presentation was characterized by sudden and intense back pain that rapidly evolved into plegia of the right leg and severe paresis of the left leg. Hypoesthesia below T6 and urinary retention were also present. The MRI showed a significant posterior spinal compression from T6 through L3 caused by an epidural hematoma that involved 10 metameric levels, extending for approximately 20 cm, with a maximum thickness of 1.6 cm from T12 to L1. Results: Within 12 hours, emergen…

Vertebral fracture, function and cognitive status in osteoporotic hip fractured women: The FOCUS study

2017

Osteoporosis is characterizated by low bone mass and microarchitectural modifications of bone tissue with a consequent increase in fragility fracture.

Is there a relationship between idiopathic scoliosis and body 2 mass? A scoping review

2022

The etiopathogenesis of idiopathic scoliosis remains unknown, although genetic or hered- 12 itary factors, neurological disorders, hormonal and metabolic dysfunctions, biomechanical factors, 13 and environmental factors seem to be involved. Several studies have found that patients with scoli- 14 osis have common characteristics of taller stature, lower body mass index (BMI), and low systemic 15 bone mass. We conducted a scoping review to analyze the association between idiopathic scoliosis 16 and BMI. The search for articles was performed on PubMed and Cochrane, including the English 17 language, full-text and free-full-text articles published from December 31st, 2011 to December 31st, 18 2…

Prevalence of Spinal Muscular Atrophy in the Era of Disease-Modifying Therapies: An Italian Nationwide Survey.

2022

ObjectiveSpinal muscular atrophy (SMA) is a neurodegenerative disorder caused by mutations in the SMN1 gene. The aim of this study was to assess the prevalence of SMA and treatment prescription in Italy.MethodsAn online survey was distributed to 36 centers identified by the Italian government as referral centers for SMA. Data on the number of patients with SMA subdivided according to age, type,SMN2copy number, and treatment were collected.ResultsOne thousand two hundred fifty-five patients with SMA are currently followed in the Italian centers with an estimated prevalence of 2.12/100,000. Of the 1,255, 284 were type I, 470 type II, 467 type III, and 15 type IV with estimated prevalence of 0…

Apolipoprotein A1 in Cerebrospinal Fluid Is Insufficient to Distinguish Alzheimer's Disease from Other Dementias in a Naturalistic, Clinical Setting.

2020

Apolipoprotein A1 (ApoA1) is the major protein component of the high-density lipoprotein and involved in cholesterol transport. Disruption of cholesterol homeostasis has been identified as a contributing factor for Alzheimer's disease (AD). Moreover, polymorphisms of ApoA1 have been associated with higher risk of disease onset and cognitive decline. Therefore, ApoA1 has been suggested as a biomarker in AD. Here, we tested a small cohort of AD and non-AD dementia patients and measured levels of ApoA1 in cerebrospinal fluid. Our results indicate that ApoA1 might not be applicable to distinguish AD from other forms of dementia.

Validation of the use of Actigraph GT3X accelerometers to estimate energy expenditure in full time manual wheelchair users with spinal cord injury.

2013

Study design: Cross-sectional validation study. Objectives: The goals of this study were to validate the use of accelerometers by means of multiple linear models (MLMs) to estimate the O2 consumption (VO2) in paraplegic persons and to determine the best placement for accelerometers on the human body. Setting: Non-hospitalized paraplegics’ community. Methods: Twenty participants (age=40.03 years, weight=75.8 kg and height=1.76 m) completed sedentary, propulsion and housework activities for 10 min each. A portable gas analyzer was used to record VO2. Additionally, four accelerometers (placed on the non-dominant chest, non-dominant waist and both wrists) were used to collect second-by-second a…

New method of bone reconstruction designed for skull base surgery

2008

The direct endonasal or transoral transclival approaches to the skull base permit effective, minimally invasive surgery along the clivus. Developing long-term, effective techniques to prevent cerebrospinal fluid (CSF) leaks and their consequences (infection and delayed healing) remains a major challenge. In this study we describe a method of bone reconstruction newly developed by us, which uses a custom designed silicone plug for bone replacement after minimally invasive skull base surgery with a low incidence of postoperative CSF leaks. German Landrace pigs were used to test the efficiency of the new technique. Twelve craniotomies were performed in six pigs using a subtemporal approach and…