Search results for "Spinal"

showing 10 items of 906 documents

The early changes in trunk muscle strength and disability following lumbar spine fusion

2012

To analyze trunk muscle function pre- and postoperatively in patients undergoing lumbar spine fusion. Associations between changes in trunk muscle strength and disability were also studied.A total of 114 patients undergoing lumbar spine fusion participated in the study. The flexion and extension strength of the trunk was measured preoperatively and 3 months after surgery using a strain-gauge dynamometer. Disability and pain during the past week was evaluated with the Oswestry disability index (ODI) and visual analog scale (VAS), respectively.Preoperative trunk extension and flexion strength levels were 319 N and 436 N in males, respectively, and 160 N and 214 N in females, respectively. In …

musculoskeletal diseasesAdultMaleMuscle Strength Dynamometermedicine.medical_specialtyTime FactorsLumbar spine fusionVisual analogue scaleMuscle Strength DynamometerDisability EvaluationSurveys and QuestionnairesMedicineHumansDisabled PersonsMuscle StrengthProspective StudiesRange of Motion ArticularProspective cohort studyMuscle SkeletalAgedPain MeasurementPain PostoperativeLumbar Vertebraebusiness.industryRehabilitationTorsota3141Recovery of FunctionTorsoMiddle AgedTrunkSurgeryOswestry Disability Indexmedicine.anatomical_structureSpinal FusionTreatment OutcomeBack PainFemalebusinessRange of motionFollow-Up StudiesDisability and Rehabilitation
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Transdermal nitroglycerine treatment of shoulder tendinopathies in patients with spinal cord injuries.

2011

A clinical blind study was conducted to determine the efficacy of transdermal nitroglycerine treatment on the awareness of shoulder pain. This study aims to determine the effects of transdermal nitroglycerine on shoulder pain and on functional shoulder movement in patients with spinal cord injuries and shoulder tendinopathies. A second aim is to establish the side effects of the treatment. Hospital “La Fe” in Valencia, Spain. A total of 45 spinal cord injury patients, all of whom are wheelchair users with shoulder tendinopathy, were randomly divided into two groups: placebo (n=12) and experimental (n=33). The experimental group (EG) received transdermal treatment for 6 months in the form of…

musculoskeletal diseasesAdultMaleShouldersVasodilator AgentsTransdermal PatchPlaceboNitroglycerinDouble-Blind MethodShoulder PainmedicineHumansSpinal cord injuryFunctional movementSpinal Cord InjuriesTransdermalbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseSpinal cordPlacebo Effectmedicine.anatomical_structureTreatment OutcomeNeurologyAnesthesiaTendinopathyFemaleNeurology (clinical)TendinopathybusinessRange of motionhuman activitiesSpinal cord
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Rates of Upper Facet Joint Violation in Minimally Invasive Percutaneous and Open Instrumentation: A Comparative Cohort Study of Different Insertion T…

2017

Background Minimally invasive pedicle screw placement may have a higher incidence of violation of the superior cephalad unfused facet joint. Study Aims We investigated the incidence and risk factors of upper facet joint violation in percutaneous robot-assisted instrumentation versus percutaneous fluoroscopy-guided and open transpedicular instrumentation. Methods A retrospective study including all consecutive patients who underwent lumbar instrumentation, fusion, and decompression for spondylolisthetic stenosis and degenerative disk disease was conducted between January 2012 and January 2016. All operations were performed by the same surgeon; the patients were divided into three groups acc…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyPercutaneousDecompressionIntervertebral Disc DegenerationSurgical planningNeurosurgical ProceduresZygapophyseal JointFacet joint03 medical and health sciences0302 clinical medicineLumbarSpinal StenosisPedicle ScrewsRisk FactorsmedicineHumansInstrumentation (computer programming)AgedRetrospective Studies030222 orthopedicsLumbar Vertebraebusiness.industryRetrospective cohort studyMiddle Agedmusculoskeletal systemmedicine.diseaseSurgeryStenosismedicine.anatomical_structureSpinal FusionTreatment OutcomeSurgeryFemaleNeurology (clinical)business030217 neurology & neurosurgeryJournal of neurological surgery. Part A, Central European neurosurgery
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A comparison of lumbopelvic motion patterns and erector spinae behavior between asymptomatic subjects and patients with recurrent low back pain durin…

2015

Objectives: The purpose of this study was to determine the patterns of lumbopelvic motion and erector spinae (ES) activity during trunk flexion-extension movements and to compare these patterns between patients with recurrent low back pain (LBP) in their pain-free periods and matched asymptomatic subjects. Methods: Thirty subjects participated (15 patients with disc herniation and recurrent LBP in their pain-free periods and 15 asymptomatic control subjects). A 3-dimensional videophotogrammetric system and surface electromyography (EMG) were used to record the angular displacements of the lumbar spine and hip in the sagittal plane and the EMG activity of the ES during standardized trunk fle…

musculoskeletal diseasesAdultMalemedicine.medical_specialtyPeriodicityMovementMuscle RelaxationLumbar RegionPostureParaspinal MusclesLumbar vertebraeElectromyographyAsymptomaticLumbarImaging Three-DimensionalRecurrenceReference ValuesMedicineHumansRange of Motion ArticularAgedLumbar Vertebraemedicine.diagnostic_testbusiness.industryElectromyographyLumbosacral RegionMiddle Agedmusculoskeletal systemTrunkLow back painSagittal planeBiomechanical Phenomenabody regionsmedicine.anatomical_structureMuscle relaxationCase-Control StudiesPhysical therapyFemaleChiropracticsmedicine.symptombusinessLow Back PainJournal of manipulative and physiological therapeutics
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Transverse fracture-dislocation of the sacrum: a diagnostic pitfall and a surgical challenge.

2002

Transverse fracture-dislocations of the sacrum are rare. Associated lesions of the lumbosacral spine as well as neurological injuries are common. Conventional radiographs of the pelvis often fail to clearly visualize the fracture. Delayed diagnosis increases the risk of progressive neurological disfunction. True lateral sacral views and CT-scans with 3-dimensional reconstructions are very helpful in establishing the full extent of the injury. These examinations should be considered in all patients with a history of high energy trauma and clinical signs indicating lumbosacral injury, such as severe low back pain and neurological disturbances of the lower extremities. The management of transv…

musculoskeletal diseasesAdultMalemedicine.medical_specialtySacrumNerve rootBone ScrewsJoint DislocationsFracture Fixation InternalDeformityMedicineHumansSpinal canalPelvisPalsyLumbar Vertebraebusiness.industryGeneral Medicinemusculoskeletal systemSacrumLow back painInternal FixatorsSurgeryRadiographymedicine.anatomical_structureSpinal FracturesSurgeryFemalemedicine.symptomNervous System DiseasesbusinessLumbosacral jointActa chirurgica Belgica
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Phenotypic spectrum and genomics of undiagnosed arthrogryposis multiplex congenital

2022

BackgroundArthrogryposis multiplex congenita (AMC) is characterised by congenital joint contractures in two or more body areas. AMC exhibits wide phenotypic and genetic heterogeneity. Our goals were to improve the genetic diagnosis rates of AMC, to evaluate the added value of whole exome sequencing (WES) compared with targeted exome sequencing (TES) and to identify new genes in 315 unrelated undiagnosed AMC families.MethodsSeveral genomic approaches were used including genetic mapping of disease loci in multiplex or consanguineous families, TES then WES. Sanger sequencing was performed to identify or validate variants.ResultsWe achieved disease gene identification in 52.7% of AMC index pati…

musculoskeletal diseasesArtrogriposi múltiple congènitaSettore BIO/18 - GENETICAhuman geneticsneuromuscular diseasesGenomicsBiologyCONTRACTURESCLASSIFICATIONdiseasessymbols.namesakeDiagnòsticGene mappingarthrogryposis multiplex congenitaExome SequencingOF-FUNCTION MUTATIONSGeneticsMedicine and Health SciencesgenomicsHumansGenetics (clinical)Exome sequencingArthrogryposisSanger sequencingGeneticsArthrogryposis multiplex congenitaGenetic heterogeneitySPINAL MUSCULAR-ATROPHYProteinsnervous system malformationsDYSTROPHYDisease gene identificationGENEHuman geneticsPedigreeETIOLOGYPhenotypesymbolsneuromuscularGenèticaTranscription Factors
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Central Neural Blocks

1988

The spinal column consists of vertebral bodies which together form 7 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 4 coccygeal vertebrae (see Transparency 1). A typical vertebra consists of two basic parts: the ventral vertebral body and the dorsal vertebral arch. Between the vertebral bodies are the intervertebral disks, which give the spinal column its flexibility. Together, the vertebral bodies and the intervertebral disks form a strong column supporting the head and trunk, while the vertebral arch protects the spinal cord. When the spinal column is viewed from the side, four flexures are visible: the thoracic and the sacrococcygeal flexures are concave ventrally, while the cervical and…

musculoskeletal diseasesCoccygeal Vertebrabusiness.industryAnatomySpinal cordTrunkSpinal columnEpidural spaceVertebraIntervertebral diskmedicine.anatomical_structureLumbarMedicinebusiness
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Biomechanical testing of different posterior fusion devices on lumbar spinal range of motion.

2019

Abstract Background Recent minimal-invasive posterior fusion devices are supposed to provide stability and obtain fusion in combination with interbody cages in the instrumented segment. The aim of the present study is to evaluate the primary stability of two minimal-invasive posterior prototypes compared to an established spinous process plate and standard pedicle screw instrumentation. Methods Seven fresh frozen human cadaver lumbar spines (L2–L5) were tested in a spinal testing device with a moment of 7.5 Nm. Spinal stability was determined as mean range of motion (RoM) in the segment L3/L4 during extension-flexion, lateral bending and axial rotation. The RoM was measured during five cond…

musculoskeletal diseasesFacet (geometry)Materials scienceRotationBiophysics03 medical and health sciencesFixation (surgical)0302 clinical medicineLumbarCadaverBone platemedicineCadaverHumansOrthopedics and Sports MedicineRange of Motion ArticularLumbar VertebraeBiomechanicsLumbosacral RegionLumbar spinal stenosis030229 sport sciencesmusculoskeletal systemmedicine.diseaseBiomechanical PhenomenaSpinal FusionRange of motionBone Plates030217 neurology & neurosurgeryBiomedical engineeringClinical biomechanics (Bristol, Avon)
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Leukodiapedesis and leukocyte migration in the leptomeninges and in the subarachnoid space.

1981

Pleocytosis in cerebrospinal fluid and infiltration of the leptomeningeal tissue have been studied after injection of ferritin into the subarachnoid space (SAS) of cats. The most important source of granulocytes in the leptomeninges are the relatively large veins of the pia mater, which have very thin walls. Passing between the lining cells of the pia mater the granulocytes leave the connective tissue space of the pia mater and reach the SAS. Leukodiapedesis has also been observed in veins crossing the SAS. During this process, gaps between the lining cells of the perivascular leptomeningeal sheath may develop. There are two possible ways for the granulocytes to pass from the vascular pia m…

musculoskeletal diseasesLeukocyte migrationDura materSubarachnoid SpaceVeinsCerebrospinal fluidCell MovementmedicineLeukocytesAnimalsintegumentary systemPia materChemistryLeptomeningesMeningesAnatomymusculoskeletal systemmedicine.diseasemedicine.anatomical_structurenervous systemNeurologyCatsPia MaterNeurology (clinical)Dura MaterSubarachnoid spaceArachnoidInfiltration (medical)Journal of neurology
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High frequency of lumbar fusion in patients denied surgical treatment of the sacroiliac joint.

2019

Purpose: Effective treatment of medical conditions relies on proper diagnosis. Clinical trials show the safety and effectiveness of sacroiliac joint (SIJ) fusion in patients with chronic SI joint dysfunction. To what extent is the condition under recognised? Objective: To determine whether under recognition of SIJ pain affects healthcare trajectories in Spanish patients with low back pain. Methods: Retrospective study of characteristics and consequences of 189 patients with persistent SIJ pain seen in an outpatient neurosurgery clinic. Results: Patients with SIJ pain who were denied surgical treatment had a longer pain duration, higher likelihood of prior lumbar fusion, and a high rate (63%…

musculoskeletal diseasesMalemedicine.medical_specialtyTime FactorsSacroiliac joint pain03 medical and health sciences0302 clinical medicineLumbarCirurgia operatòriamedicineEffective treatmentHumansIn patientSurgical treatmentRetrospective StudiesSacroiliac jointbusiness.industryLumbosacral RegionSacroiliac JointGeneral MedicineMiddle AgedLow back painArthralgiaSurgeryClinical trialmedicine.anatomical_structureSpinal FusionTreatment Outcome030220 oncology & carcinogenesisSurgeryFemaleNeurology (clinical)Lumbàlgiamedicine.symptomChronic PainbusinessLow Back Pain030217 neurology & neurosurgeryBritish journal of neurosurgery
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