Search results for "Spine."

showing 10 items of 390 documents

Thirty years of synaptosome research.

1993

Detached synapses (synaptosomes), first isolated by the author in 1958 and identified as such in 1960, are sealed presynaptic nerve terminals often with a portion of the target cell--sometimes amounting to a complete dendritic spine--adhering to their external surface. They can be prepared in high yield from brain tissue and also in decreasing yield from spinal cord, retina, sympathetic ganglia, myenteric plexus and electric organs. They are sealed structures which, under metabolizing conditions, respire, take up oxygen and glucose, extrude Na+, accumulate K+, maintain a normal membrane potential and, on depolarization, release transmitter in a Ca(2+)-dependent manner. They thus provide an …

SynaptosomeNervous systemMembrane potentialNeurotransmitter AgentsHistologyDendritic spineGeneral NeuroscienceResearchModels NeurologicalDepolarizationCell BiologyBiologySynaptic vesicleSynapsemedicine.anatomical_structureSynapsesmedicineBiophysicsCentrifugation Density GradientAnimalsAnatomyNeuroscienceMyenteric plexusSynaptosomesJournal of neurocytology
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Differential evolution of PSA-NCAM expression during aging of the rat telencephalon

2007

Changes in the ability of neuronal networks to undergo structural remodeling may be involved in the age-associated cognitive decline. The polysialylated form of the neural cell adhesion molecule (PSA-NCAM) declines dramatically during postnatal development, but persists in several regions of the young-adult rat telencephalon, where it participates, through its anti-adhesive properties, in neuronal structural plasticity. However, PSA-NCAM expression during aging has only been studied in the dentate gyrus and the piriform cortex layer II, where it is strongly downregulated in adult (middle-aged) individuals. Using immunohistochemistry, we have observed that in most of the telencephalic areas …

TelencephalonAgingDendritic SpinesDown-RegulationHippocampusCell CountNeural Cell Adhesion Molecule L1BiologyPiriform cortexCell AdhesionLimbic SystemmedicineNeuropilAnimalsCognitive declineCerebral CortexNeuronsNeuronal PlasticityNeocortexGeneral NeuroscienceDentate gyrusAmygdalaImmunohistochemistryRats Inbred F344RatsDisease Models Animalmedicine.anatomical_structurenervous systemSialic AcidsFemaleNeural cell adhesion moleculeNeurology (clinical)Geriatrics and GerontologyNeuroscienceBiomarkersDevelopmental BiologyStratum lucidumNeurobiology of Aging
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Thermal stability and reactivity in oxygen of potassium ferrites with spinel structure

1990

The potassium content really incorporated in the spinel lattice of the magnetite determined by thermogravimetric analysis in vacuum or in oxygen was about 2.45 wt%. In spite of this low content, the potassium strongly stabilises the defect spinel structure resulted by the potassium-substituted magnetite oxidation and increases the transformation temperature of the defect phases into α-Fe2O3 or KFe11O17.

Thermogravimetric analysisPotassiumSpinelKineticsInorganic chemistrychemistry.chemical_elementengineering.materialOxygenThermogravimetrychemistry.chemical_compoundchemistryengineeringThermal stabilityMagnetiteJournal of Thermal Analysis
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Analysis of the oxidation process and mechanical evolution in nanosized copper spinel ferrites. Role of stresses on the coercivity

1997

Isothermal oxidations of the iron(II) and copper(I) cations in nanosized copper spinel ferrites which were oxidized in cation-deficient spinels have been studied by thermogravimetric analysis. The low temperature kinetics of oxidation of each oxidizable cation has been explained on the basis of a diffusion-induced stress effect, these stresses being generated in the ferrite particles by the chemical gradient induced during the oxidation process where the cations at the surface are more oxidized than those in the bulk. A reaction mechanism coupling the chemical and the mechanical effects has been proposed. When the Cu-ferrites contain some Co-cations, it has also been revealed that the stres…

Thermogravimetric analysisReaction mechanismMaterials scienceSpinelKineticsInorganic chemistrychemistry.chemical_elementCoercivityengineering.materialCondensed Matter PhysicsCopperIsothermal processchemistryengineeringFerrite (magnet)General Materials ScienceMaterials Chemistry and Physics
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Use of Machine Learning and Artificial Intelligence to Drive Personalized Medicine Approaches for Spine Care

2020

Personalized medicine is a new paradigm of healthcare in which interventions are based on individual patient characteristics rather than on “one-size-fits-all” guidelines. As epidemiological datasets continue to burgeon in size and complexity, powerful methods such as statistical machine learning and artificial intelligence (AI) become necessary to interpret and develop prognostic models from underlying data. Through such analysis, machine learning can be used to facilitate personalized medicine via its precise predictions. Additionally, other AI tools, such as natural language processing and computer vision, can play an instrumental part in personalizing the care provided to patients with …

Traumatic spinal cord injuryPrognosiPsychological interventionPatient characteristicsDiseaseSpinal cord injuryMachine learningcomputer.software_genreSpinal DiseaseMachine Learning03 medical and health sciences0302 clinical medicineArtificial IntelligenceHealth careFunctional StatuMedicineHumansSpine carePrecision MedicineDegenerative cervical myelopathyPrognostic modelsSpinal Cord InjuriesNatural Language ProcessingSpinal Cord Injuriebusiness.industryPrognosisPersonalized medicineFunctional Status030220 oncology & carcinogenesisSurgeryFunctional statusSpinal DiseasesNeurology (clinical)Personalized medicineArtificial intelligenceSpondylosisbusinesscomputerSpinal Cord Compression030217 neurology & neurosurgeryHuman
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Correlation between oxidation states of transition metal ions and variation of the coercivity in mixed-valence defect spinel ferrites

1997

Abstract Due to the very high dispersion of mixed-valence spinel ferrites prepared by ‘soft chemistry’ it becomes possible to oxidize in the spinel lattice, not only ferrous ions but also different transition metal ions (Cr 3+ , Mn 2+ , Mn 3+ , Mo 3+ , Mo 4+ V 2+ , V 3+ , Cu + ), by ‘soft’ oxidation between 150 and 500°C, under formation of non-stoichiometric spinels cation vacancies. The oxidation state with the coordination and the oxidation temperature of the cations have been determined in coppermanganese ferrites by derivative thermogravimetry (DTG), based on the specific solid-state reactivity of cations in the redox reaction. For Co-modified non-stoichiometric spinels, which present…

Valence (chemistry)ChemistryInorganic chemistrySpinelGeneral ChemistryCoercivityengineering.materialCondensed Matter PhysicsRedoxSoft chemistryThermogravimetryCrystallographyOxidation stateengineeringGeneral Materials ScienceIron oxide cycle
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Exploring wet chemistry approaches to ZnFe2O4 spinel ferrite nanoparticles with different inversion degrees: A comparative study

2019

Zinc ferrite (ZnFe2O4) spinel nanocrystals were synthesised through three different low-temperature routes, namely hydrothermal, combined miniemulsion/hydrothermal, and microwave-assisted non-aqueous sol–gel synthesis. With the aim of studying the influence of the respective approach on the structural evolution of the compounds during the synthetic process, the samples were prepared with different processing times. The resulting nanoparticles were inspected with a wide range of analytical techniques, both with regards to the local (X-ray absorption spectroscopy – XAS) and the long-range (Raman spectroscopy, X-ray diffraction – XRD) order.

X-ray absorption spectroscopyMaterials scienceAbsorption spectroscopySpinel02 engineering and technologyengineering.material010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesHydrothermal circulation0104 chemical sciencesInorganic ChemistryMiniemulsionsymbols.namesakeZinc ferriteChemical engineeringsymbolsengineering0210 nano-technologyRaman spectroscopyWet chemistry
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On the classification of Kim and Kostrikin manifolds

2006

International audience; We completely classify the topological and geometric structures of some series of closed connected orientable 3-manifolds introduced by Kim and Kostrikin in [20, 21] as quotient spaces of certain polyhedral 3-cells by pairwise identifications of their boundary faces. Then we study further classes of closed orientable 3-manifolds arising from similar polyhedral schemata, and describe their topological properties.

[ MATH.MATH-GT ] Mathematics [math]/Geometric Topology [math.GT]3-manifolds; group presentations; spines; orbifolds; polyhedral schemata; branched coveringsAlgebra and Number TheorySeries (mathematics)010102 general mathematicsBoundary (topology)spines0102 computer and information sciences01 natural sciencesgroup presentations3-manifoldsCombinatoricspolyhedral schemata010201 computation theory & mathematics[MATH.MATH-GT]Mathematics [math]/Geometric Topology [math.GT]Pairwise comparisonorbifoldsbranched coverings0101 mathematicsQuotient[MATH.MATH-GT] Mathematics [math]/Geometric Topology [math.GT]Mathematics
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Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites

2005

The transmembrane form of agrin (TM-agrin) is primarily expressed in the CNS, particularly on neurites. To analyze its function, we clustered TM-agrin on neurons using anti-agrin antibodies. On axons from the chick CNS and PNS as well as on axons and dendrites from mouse hippocampal neurons anti-agrin antibodies induced the dose- and time-dependent formation of numerous filopodia-like processes. The processes appeared within minutes after antibody addition and contained a complex cytoskeleton. Formation of processes required calcium, could be inhibited by cytochalasine D, but was not influenced by staurosporine, heparin or pervanadate. Time-lapse video microscopy revealed that the processes…

animal structuresDendritic spineTime FactorsNeuriteCytochalasin BGrowth ConesVideo microscopyChick EmbryoBiologyNervous SystemAntibodiesCellular and Molecular NeuroscienceMicemedicineNeuritesAnimalsAgrinPseudopodiaGrowth coneCytoskeletonMolecular BiologyCells CulturedCytoskeletonAgrinMicroscopy VideoDose-Response Relationship DrugCell MembraneCell DifferentiationCell BiologyDendritesCell biologymedicine.anatomical_structurenervous systemAnimals NewbornNeuronFilopodia
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The change of volume of the lumbar vertebrae along with aging in asymptomatic population: a preliminary analysis

2018

Previous studies have demonstrated that the length of the lumbar spine is decreasing with age. Despite considerable research based on sagittal measurements, little is known about the changes in the volume of vertebrae. The objective of this study was to evaluate the changes in the volume of either column of the spine with age. Materials and methods: Computed tomography scans of 62 asymptomatic subjects, performed for thoracolumbar trauma evaluation were used to create virtual 3D models. At least 10 patients were assigned to every decade of life from third to eight. We used a novel technique to measure the volume of anterior column (AC) and posterior column (PC) per each segment (a total of …

asymptomatic populationaginglumbar spine alignmentVoxel-based morphometrylumbar spine alignment Voxel-based morphometry aging asymptomatic population
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