Search results for "Standard"
showing 10 items of 3299 documents
A comparison of some simple methods to identify geographical areas with excess incidence of a rare disease such as childhood leukaemia
1999
SUMMARY Six statistics are compared in a simulation study for their ability to identify geographical areas with a known excess incidence of a rare disease. The statistics are the standardized incidence ratio, the empirical Bayes method of Clayton and Kaldor, Poisson probability, a statistic based on the B statistics are compared for the proportion of true high-risk areas identi"ed in the top 1 per cent and 10 per cent of ranked areas. One of the PW statistics performed consistently well under all circumstances, although the results for the BT statistic were marginally better when only the top 1 per cent of ranked areas was considered. The standardized incidence ratio performed consistently …
Visualizing parameters from loglinear models
2004
This paper presents a graphical display for the parameters resulting from loglinear models. Loglinear models provide a method for analyzing associations between two or several categorical variables and have become widely accepted as a tool for researchers during the last two decades. An important part of the output of any computer program focused on loglinear models is that devoted to estimation of parameters in the model. Traditionally, this output has been presented using tables that indicate the values of the coefficients, the associated standard errors and other related information. Evaluation of these tables can be rather tedious because of the number of values shown as well as their r…
Empirical investigation of stock price dynamics in an emerging market
1999
Abstract We study the development of an emerging market – the Budapest Stock Exchange – by investigating the time evolution of some statistical properties of heavily traded stocks. Moving quarter by quarter over a period of two and a half years we analyze the scaling properties of the standard deviation of intra-day log-price changes. We observe scaling using both seconds and ticks as units of time. For the investigated stocks a Levy shape is a good approximation to the probability density function of tick-by-tick log-price changes in each quarter: the index of the distribution follows an increasing trend, suggesting it could be used as a measure of market efficiency.
Social capital and economic growth in Europe: nonlinear trends and heterogeneous regional effects
2016
After two decades of academic debate on the social capital-growth nexus, discussion still remains open. Most of the literature so far, however, has followed the one-size-its-all approach, neglecting that the great disparities across geographical units might have implications in this relationship. This article analyzes the role of two social capital indicators on the growth of 237 European regions in the period 1995–2007 by implementing a set of both parametric and non- parametric regressions. Whereas the former impose a linear functional form for the parameters, the latter relax this assumption providing a flexible frame in which the functional form is given by the data. The technique also …
Tests of multinormality based on location vectors and scatter matrices
2007
Classical univariate measures of asymmetry such as Pearson’s (mean-median)/σ or (mean-mode)/σ often measure the standardized distance between two separate location parameters and have been widely used in assessing univariate normality. Similarly, measures of univariate kurtosis are often just ratios of two scale measures. The classical standardized fourth moment and the ratio of the mean deviation to the standard deviation serve as examples. In this paper we consider tests of multinormality which are based on the Mahalanobis distance between two multivariate location vector estimates or on the (matrix) distance between two scatter matrix estimates, respectively. Asymptotic theory is develop…
Unacceptable implications of the left haar measure in a standard normal theory inference problem
1978
For a very common statistical problem, inference about the mean of a normal random variable, some inadmissible consequences of the left Haar invariant prior measure, which is that recommended as a suitable prior by Jeffreys’ multivariate rule and by the methods of Villegas and Kashyap, are uncovered and investigated.
On (n-l)-wise and joint independence and normality of n Random variables: an example
1981
An example is given of a vector of n random variables such that any (n-1)-dimensional subvector consists of n-1 independent standard normal variables. The whole vector however is neither independent nor normal.
Comparative Study of Human and Automated Screening for Antinuclear Antibodies by Immunofluorescence on HEp-2 Cells
2015
Background : Several automated systems had been developed in order to reduce inter-observer variability in indirect immunofluorescence (IIF) interpretation. We aimed to evaluate the performance of a processing system in antinuclear antibodies (ANA) screening on HEp-2 cells. Patients and Methods : This study included 64 ANA-positive sera and 107 ANA-negative sera that underwent IIF on two commercial kits of HEp-2 cells (BioSystems® and Euroimmun®). IIF results were compared with a novel automated interpretation system, the “ Cyclopus CADImmuno®” (CAD). Results : All ANA-positive sera images were recognized as positive by CAD (sensitivity = 100%), while 17 (15.9%) of the ANA-negative sera ima…
Testing with a nuisance parameter present only under the alternative: a score-based approach with application to segmented modelling
2016
ABSTRACTWe introduce a score-type statistic to test for a non-zero regression coefficient when the relevant term involves a nuisance parameter present only under the alternative. Despite the non-regularity and complexity of the problem and unlike the previous approaches, the proposed test statistic does not require the nuisance to be estimated. It is simple to implement by relying on the conventional distributions, such as Normal or t, and it justified in the setting of probabilistic coherence. We focus on testing for the existence of a breakpoint in segmented regression, and illustrate the methodology with an analysis on data of DNA copy number aberrations and gene expression profiles from…
On implementation of the Gibbs sampler for estimating the accuracy of multiple diagnostic tests
2010
Implementation of the Gibbs sampler for estimating the accuracy of multiple binary diagnostic tests in one population has been investigated. This method, proposed by Joseph, Gyorkos and Coupal, makes use of a Bayesian approach and is used in the absence of a gold standard to estimate the prevalence, the sensitivity and specificity of medical diagnostic tests. The expressions that allow this method to be implemented for an arbitrary number of tests are given. By using the convergence diagnostics procedure of Raftery and Lewis, the relation between the number of iterations of Gibbs sampling and the precision of the estimated quantiles of the posterior distributions is derived. An example conc…