Search results for "Standard"
showing 10 items of 3299 documents
016: Evidence of systemic plaque vulnerability in acute coronary syndromes with FDG-positron emission tomography and computed tomographic angiography…
2013
PurposeAtherosclerotic plaque vulnerability is a systemic phenomenon and is often associated with severe plaque infiltration with inflammatory cells. 18-Fluoro-deoxyglucose (FDG) accumulates in inflammatory cells of atherosclerotic plaques. The aim of this study was to assess whether 1) FDG uptake in the aorta and carotid arteries measured by positron emission tomography (PET) is higher in patients with acute coronary syndromes (ACS) than in patients with stable coronary artery disease (CAD) and; 2) associated with morphological markers of plaque instability detected with computed tomography angiography (CTA).MethodsPatients with ACS (n=50) or stable CAD (n=28) underwent a PET 90 minutes af…
Consensus on nomenclature for clinical staging models in bipolar disorder: A narrative review from the International Society for Bipolar Disorders (I…
2021
Objectives Clinical staging is widely used in medicine to map disease progression, inform prognosis and guide treatment decisions; in psychiatry, however, staging remains a hypothetical construct. To facilitate future research in bipolar disorders (BD), a well-defined nomenclature is needed, especially since diagnosis is often imprecise with blurred boundaries, and a full understanding of pathophysiology is lacking. Methods Under the auspices of the International Society of Bipolar Disorders, a Task Force of international experts was convened to review, discuss, and integrate findings from the scientific literature relevant to the development of a consensus staging model and standardize a t…
Joint protection in haemophilia
2011
Haemarthroses (intra-articular haemorrhages) are a frequent finding typically observed in patients with haemophilia. Diagnosis and treatment of these bleeding episodes must be delivered as early as possible. Additionally, treatment should ideally be administered intensively (enhanced on-demand treatment) until the resolution of symptoms. Joint aspiration plays an important role in acute and profuse haemarthroses as the presence of blood in the joint leads to chondrocyte apoptosis and chronic synovitis, which will eventually result in joint degeneration (haemophilic arthropathy). Ultrasonography (US) is an appropriate diagnostic technique to assess the evolution of acute haemarthrosis in hae…

 Interventions to Reduce Platelet Prophylactic Transfusions in Patients with Hypoproliferative Thrombocytopenia: Providing Patients with the Fu…
2013
SUMMARY To reduce the infectious and immunologic complications of platelet transfusions in patients with hypoproliferative thrombocytopenia, three interventions have aimed to decrease the number of prophylactic platelet transfusions received by such patients for the prevention of bleeding. These are the reduction of the platelet count threshold triggering prophylactic transfusion, the administration of low-dose (as opposed to standard-dose) platelet transfusions, and the administration of therapeutic (as opposed to prophylactic) platelet transfusions. We demonstrate that—in terms of absolute risk reduction in all infectious and some immunologic complications of transfusion— patients can ben…
Composition en acides gras des hémisphères cérébraux de rats spontanément hypertendus allaités par des femelles Wistar
2003
Total lipid fatty acid composition was investigated in brain hemispheres of male Spontaneously Hypertensive Rats (SHR), compared with normotensive Wistar Kyoto rats (WKY) used as controls. Both strains were suckled by adoptive Wistar mothers, and then fed a standard diet after weaning. No difference was observed between the two hemispheres of WKY killed either at 10 or 30 days. In SHR killed at 10 days, the two hemispheres showed differences, SHR left hemispheres exhibiting greater fatty acid composition changes than those of WKY, phenomenon that toned down at 30 days. Hence, SHR pups showed a different total lipid fatty acid composition of their brain hemispheres when compared with their W…
New Hope in Brain Glioma Surgery: The Role of Intraoperative Ultrasound. A Review
2018
Maximal safe resection represents the gold standard for surgery of malignant brain tumors. As regards gross-total resection, accurate localization and precise delineation of the tumor margins are required. Intraoperative diagnostic imaging (Intra-Operative Magnetic Resonance-IOMR, Intra-Operative Computed Tomography-IOCT, Intra-Operative Ultrasound-IOUS) and dyes (fluorescence) have become relevant in brain tumor surgery, allowing for a more radical and safer tumor resection. IOUS guidance for brain tumor surgery is accurate in distinguishing tumor from normal parenchyma, and it allows a real-time intraoperative visualization. We aim to evaluate the role of IOUS in gliomas surgery and to ou…
Standard treatment of female patients with breast cancer decreases substantially for women aged 70 years and older: a German clinical cohort study
2010
Standard treatment of patients with breast cancer decreases with age and older persons are mostly excluded from clinical trials. We hypothesized that non-adherence to treatment guidelines occurs for women agedor =70 years and changes overall survival (OAS) and disease-free survival (DFS).We enrolled 1922 women agedor =50 years with histologically confirmed invasive breast cancer treated at the University of Ulm from 1992 to 2005. Adherence to guidelines and effects on OAS and DFS for women agedor =70 years was compared with that for younger women (50-69 years).Women70 years less often received recommended breast-conserving therapy (70-79 years: 74%-83%;79 years: 54%) than women agedor =69 y…
The influence of Kinesiology Taping on the volume of lymphoedema and manual dexterity of the upper limb in women after breast cancer treatment.
2015
The aim of our study was to evaluate the effect of Kinesiology Taping (KT) on the size of lymphoedema and manual dexterity of the upper limb in women after breast cancer treatment. We also examined whether the application of KT can replace the traditional and standard multilayered bandaging in the treatment of upper extremity lymphoedema. Group A comprised of 22 patients who underwent KT as well as pneumatic and manual lymphatic drainage. Then, group B comprised of 23 patients who were treated with quasi-KT as well as pneumatic and manual lymphatic drainage. In contrast, group C had 25 patients subjected only to the standard procedure - pneumatic and manual lymphatic drainage and multilayer…
Color discrimination under mesopic conditions in cats and humans
1995
The ability to discriminate colors under various levels of mesopic illumination was studied in three cats using colored papers as stimuli and with a computer controlled training schedule. Discrimination based on brightness differences was prevented using a new method in which illuminant color was varied. The luminance threshold for color discrimination in cats was found to be 0.5 cd/m2, close to the cone threshold reported by others from ganglion cell recordings. The same experiment was carried out with human subjects and revealed a luminance threshold of 0.00042 cd/m2 for color discrimination.
Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical tri…
2019
Background Bromelain is a cysteine protease isolated from pineapple with a range of biological properties including platelet aggregation inhibition and anti-inflammatory effects. Recent studies have evaluated the clinical implications of bromelain in reducing postoperative inflammatory complications after third molar surgery, but the results are contrasting. This systematic review and meta-analysis evaluated the effects of bromelain on health outcomes in patients submitted to third molar surgery. Material and Methods The study was conducted following the PRISMA statement. Searches were conducted in six electronic databases and Google Scholar from inception to May 2018. The following element…