Search results for "State."
showing 10 items of 8943 documents
Authenticity as a mental state: A primer
2014
Highlights Philosophy of mind offers a new philosophical foundation for authenticity. Philosophy of mind studies mental states, whose defining property is intentionality. Intentionality is an essential trait in any characterization of authenticity. Experiencing authenticity is a mental state. Authenticity’s role as a theoretical construct is strengthened and amplified.
Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer
2019
Este es el artículo que se ha publicado de forma definitiva en: https://molecularautism.biomedcentral.com/articles/10.1186/s13229-019-0262-8 En este artículo también participa Joan Climent, Vera Pancaldi, Lourdes Fañanás, Celso Arango, Mara Parellada, Anaïs Baudot, Daniel Vogt, John L. Rubenstein, Alfonso Valencia y Rafael Tabarés-Seisdedos. Background: Epidemiological and clinical evidence points to cancer as a comorbidity in people with autism spectrum disorders (ASD). A significant overlap of genes and biological processes between both diseases has also been reported. Methods: Here, for the first time, we compared the gene expression profiles of ASD frontal cortex tissues and 22 cancer t…
Imaging of LED-excited autofluorescence photobleaching rates for skin diagnostics
2019
The aim of this study is to develop a novel non-invasive approach for skin cancer (melanoma, basal cell and squamous cell carcinomas) diagnostics by mapping the AF intensity decrease (photo-bleaching) rates under continuous 405 nm LED excitation. For parametric mapping of skin AF intensity decrease rates a sequence of filtered AF imaging under 405 nm LED excitation for 20 seconds at a power density of ~7 mW/cm2 with a frame rate 0.5 fps was recorded and analyzed by cloud-based prototype device. Several clinical cases and potential future applications of the proposed autofluorescence photobleaching rate imaging technique are discussed.
Decomposing and Interpreting Spatial Effects in Spatio-Temporal Analysis: Evidences for Spatial Data Pooled Over Time
2017
Empirical applications using individual spatial data pooled over time usually neglect the fact that such data are not only spatially localized: they are also collected over time, i.e. temporally localized. So far, little effort has been devoted to proposing a global way for dealing with spatial data (cross-section) pooled over time, such as real estate transactions, business start-up, crime and so on. However, the spatial effect, in such a context, can be decomposed in two different components: a multidirectional spatial effect (same time period) and a unidirectional spatial effect (previous time period). Based on real estate literature, this chapter presents different spatio-temporal autor…
A Comprehensive Spatiotemporal Framework for Hedonic Pricing: Integrating the Comparable Sales Approach and Minimizing Spatial Omitted Variable Bias
2019
This paper develops a theoretical and methodological framework that integrates Hedonic Pricing (HP), grid comparable sales approach (CSA), and nearest neighbors into a general spatiotemporal specification. By explicitly providing a theoretical justification for introducing spatial (or spatiotemporal) econometrics to HP, this approach is not only relevant to house price forecasting and automated valuation models (AVM) but also to valuing environmental goods capitalized in housing and to all other fields employing house pricing models. The resulting econometric CSA and spatiotemporal Durbin models provide higher prediction accuracy and reliability to alternatives by reducing the spatially-del…
Sguardo di ascolto: note di ricerca sul film Aylesbury Estate (2020)
2022
Aylesbury Estate (2020) è un lungometraggio documentario sul noto complesso abitativo di social housing londinese, nel quale ho abitato per alcuni anni. Il film, da me diretto tra il 2017 e il 2020, segue il percorso esistenziale ed emotivo di alcuni residenti dell’Aylesbury mentre si fa strada il lungo processo di demolizione dello stesso. Nel ripercorrere il processo di realizzazione del film e attraverso l’analisi di alcune sequenze del film finito, questo articolo propone uno ‘sguardo di ascolto’ per condurre ricerca sul campo attraverso il mezzo filmico.
Stepwise formation of a pentanuclear Ni4Cu heterometallic complex exhibiting a vertex-sharing defective double-cubane core and diphenoxo- and phenoxo…
2013
Sequential reaction of a N5O3 octadentate tripodal ligand with Ni(2+) and subsequently with Cu(2+) and azide ligand afforded the first example of a heterobridged (phenoxo/μ(1,1)-azido) pentanuclear heterometallic (Ni4Cu) compound, which exhibits a centrosymmetric vertex-sharing defective double-cubane structure. The study of the magnetic properties reveals that the compound shows ferromagnetic interaction interactions, leading to an S = 9/2 spin ground state. Density functional theory calculations on the X-ray structure and model compounds predict ferromagnetic interactions through the magnetic exchange pathways involving each couple of metal ions.
Novel azobenzene precursors for NLO active polyuretanes: Synthesis, quantum chemical and experimental characterization
2009
Abstract For the development of electro optical active polyurethanes six new derivatives of 2-{(2-hydroxyethyl)-[4-(4-nitrophenylazo)phenyl]amino}ethanol and two of 2-{(2-hydroxyethyl)-[4-(5-nitropyridin-2-ylazo)phenyl]amino}ethanol were synthesized by azocoupling reaction. Molecular geometry, hyperpolarizability βFF and ground state dipole moment μg were acquired by RHF ab initio (6–31G∗∗) calculations using HyperChem software package. To characterize NLO performance of synthesized azo compounds second order non linear coefficients d31 and d33 were measured as function of chromophore load in guest–host films (PMMA). Eight synthesized compounds can be grouped in four similar gross formula p…
Observation of an Excited $B^{\pm}_c$ Meson State with the ATLAS Detector
2014
A search for excited states of the B±c meson is performed using 4.9 fb-1 of 7 TeV and 19.2 fb-1 of 8 TeV pp collision data collected by the ATLAS experiment at the LHC. A new state is observed through its hadronic transition to the ground state, with the latter detected in the decay B±c→J/ψπ±. The state appears in the m(Bc±π+π-)-m(Bc±)-2m(π±) mass difference distribution with a significance of 5.2 standard deviations. The mass of the observed state is 6842±4±5 MeV, where the first error is statistical and the second is systematic. The mass and decay of this state are consistent with expectations for the second S-wave state of the B±c meson, B±c(2S).
Bile acid–cysteamine conjugates: Structural properties, gelation, and toxicity evaluation
2011
Abstract Design, synthesis, and characterization of six novel bile acid–cysteamine conjugates together with investigation of their structural studies, gelation properties, and preliminary toxicity evaluation, are reported. Solid state properties of selected compounds were studied by means of X-ray diffraction and 13C CPMAS NMR spectroscopy. N-(2-thioethyl)-3α,7α,12α-trihydroxy-5β-cholan-24-amide was shown to exhibit (pseudo)polymorphism, and a single crystal structure of its non-stoichiometric hydrate is reported herein. Cholyl and dehydrocholyl derivatives bearing three functionalities in their steroidal backbone were shown to undergo self-assembly leading to gelation in certain organic so…