Search results for "State"

showing 10 items of 9165 documents

On the N1-H and N3-H Bond Dissociation in Uracil by Low Energy Electrons: A CASSCF/CASPT2 Study.

2015

The dissociative electron-attachment (DEA) phenomena at the N1-H and N3-H bonds observed experimentally at low energies (<3 eV) in uracil are studied with the CASSCF/CASPT2 methodology. Two valence-bound π(-) and two dissociative σ(-) states of the uracil anionic species, together with the ground state of the neutral molecule, are proven to contribute to the shapes appearing in the experimental DEA cross sections. Conical intersections (CI) between the π(-) and σ(-) are established as the structures which activate the DEA processes. The N1-H and N3-H DEA mechanisms in uracil are described, and experimental observations are interpreted on the basis of two factors: (1) the relative energy of …

010304 chemical physicsChemistryHydrogen bondUracilElectronBond breaking010402 general chemistry01 natural sciencesDissociation (chemistry)0104 chemical sciencesComputer Science ApplicationsCrystallographychemistry.chemical_compoundLow energyComputational chemistry0103 physical sciencesPhysical and Theoretical ChemistryGround stateNeutral moleculeJournal of chemical theory and computation
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A QM/MM Approach Using the AMOEBA Polarizable Embedding: From Ground State Energies to Electronic Excitations

2016

International audience; A fully polarizable implementation of the hybrid Quantum Mechanics/Molecular Mechanics approach is presented, where the classical environment is described through the AMOEBA polarizable force field. A variational formalism, offering a self-consistent 1 relaxation of both the MM induced dipoles and the QM electronic density is used for ground state energies and extended to electronic excitations in the framework of Time-Dependent Density Functional Theory combined with a state specific response of the classical part. An application to the calculation of the solvatochromism of the pyridinium N-phenolate betaine dye used to define the solvent ET30 scale is presented. Th…

010304 chemical physicsChemistryPolarizable force fieldSolvatochromismQuantum Chemistry010402 general chemistryElementary chargeQM/MM01 natural sciences0104 chemical sciencesComputer Science Applications[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistryQM/MMQM/MM; Polarisable embedding; Physical and Theoretical ChemistryPolarizabilityQuantum mechanics0103 physical sciencesPolarisable embeddingDensity functional theorypolarizable force field AMOEBAPhysical and Theoretical ChemistryGround stateExcitationElectronic densityJournal of Chemical Theory and Computation
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Origin of Enzymatic Kinetic Isotope Effects in Human Purine Nucleoside Phosphorylase

2017

Here we report a study of the effect of heavy isotope labeling on the reaction catalyzed by human purine nucleoside phosphorylase (hPNP) to elucidate the origin of its catalytic effect and of the enzymatic kinetic isotope effect (EKIE). Using quantum mechanical and molecular mechanical (QM/MM) molecular dynamics (MD) simulations, we study the mechanism of the hPNP enzyme and the dynamic effects by means of the calculation of the recrossing transmission coefficient. A free energy surface (FES), as a function of both a chemical and an environmental coordinate, is obtained to show the role of the environment on the chemical reaction. Analysis of reactive and nonreactive trajectories allows us …

010304 chemical physicsChemistryPurine nucleoside phosphorylasevariational transition state theoryGeneral Chemistry010402 general chemistryenzyme catalysis01 natural sciencesChemical reactionCatalysis0104 chemical sciencesEnzyme catalysisCatalysisSolventMolecular dynamicsComputational chemistryenzymatic kinetic isotope effect0103 physical sciencesKinetic isotope effectMoleculeQM/MM methodsprotein motionsACS Catalysis
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A quantum dynamics study of the benzopyran ring opening guided by laser pulses

2014

Abstract The ring-opening photoisomerization of benzopyran, which occurs via a photochemical route involving a conical intersection, has been studied with quantum dynamics calculations using the multi-configuration time-dependent Hartree method (MCTDH). We introduce a mechanistic strategy to control the conversion of benzopyran to merocyanine with laser pulses. We use a six-dimensional model developed in a previous work for the potential energy surfaces (PES) based on an extension of the vibronic-coupling Hamiltonian model (diabatization method by ansatz), which depends on the most active degrees of freedom. The main objective of these quantum dynamics simulations is to provide a set of str…

010304 chemical physicsChemistryQuantum dynamicsDegrees of freedom (physics and chemistry)General Physics and AstronomyHartreeConical intersection010402 general chemistry01 natural sciencesPotential energyMolecular physics0104 chemical sciences[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistrysymbols.namesakeStark effectComputational chemistry0103 physical sciences[ CHIM.THEO ] Chemical Sciences/Theoretical and/or physical chemistrysymbolsPhysical and Theoretical ChemistryGround stateAdiabatic processComputingMilieux_MISCELLANEOUS
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Full-dimensional control of the radiationless decay in pyrazine using the dynamic Stark effect

2014

We present a full quantum-mechanical study of the laser control of the radiationless decay between the B3u(nπ(*)) and B2u(ππ(*)) states of pyrazine using the dynamic Stark effect. In contrast to our previous study [Sala et al., J. Chem. Phys. 140, 194309 (2014)], where a four-dimensional model was used, all the 24 degrees of freedom are now included in order to test the robustness of the strategy of control. Using a vibronic coupling Hamiltonian model in a diabatic representation, the multi-layer version of the multi-configuration time-dependent Hartree method is exploited to propagate the corresponding wave packets. We still observe a trapping of the wavepacket on the B2u(ππ(*)) potential …

010304 chemical physicsChemistryWave packetDiabaticGeneral Physics and AstronomyHartree010402 general chemistry01 natural sciencesPotential energy0104 chemical sciences[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistryVibronic couplingsymbols.namesakeStark effectQuantum mechanicsExcited state[ CHIM.THEO ] Chemical Sciences/Theoretical and/or physical chemistry0103 physical sciencesPotential energy surfacesymbolsPhysics::Atomic PhysicsPhysics::Chemical PhysicsPhysical and Theoretical ChemistryAtomic physicsComputingMilieux_MISCELLANEOUSThe Journal of Chemical Physics
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Germanium Dicarbide: Evidence for a T-Shaped Ground State Structure

2017

The equilibrium structure of germanium dicarbide GeC2 has been an open question since the late 1950s. Although most high-level quantum calculations predict an L-shaped geometry, a T-shaped or even a linear geometry cannot be ruled out because of the very flat potential energy surface. By recording the rotational spectrum of this dicarbide using sensitive microwave and millimeter techniques, we unambiguously establish that GeC2 adopts a vibrationally averaged T-shaped structure in its ground state. From analysis of 14 isotopologues, a precise r0 structure has been derived, yielding a Ge–C bond length of 1.952(1) A and an apex angle of 38.7(2)°.

010304 chemical physicsChemistrychemistry.chemical_elementLinear molecular geometryGermanium02 engineering and technology021001 nanoscience & nanotechnology01 natural sciencesMolecular physicsBond lengthCrystallography0103 physical sciencesPotential energy surfaceGeneral Materials ScienceMillimeterIsotopologuePhysical and Theoretical Chemistry0210 nano-technologyGround stateMicrowaveThe Journal of Physical Chemistry Letters
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Dynamic Polarizability and Higher-Order Electric Properties of Fluorene, Carbazole, and Dibenzofuran

2019

Static electric properties, from the dipole moment to the second-hyperpolarizability tensor γ, of the 3-membered, isoelectronic ring molecules, fluorene (FL), carbazole (CR), and dibenzofuran (DBF), have been calculated at various levels of approximation. The electron correlation effects have been included at the coupled-cluster (CC) level, using CCSD and CC2 versions of the method. DFT calculations with the CAM-B3LYP functional have also been performed, and the results are compared to the CC values. The electric property-tailored Pol basis set and its more compact Z3Pol version have been employed in all static calculations. Differences between dipole polarizability values computed at the P…

010304 chemical physicsElectronic correlationChemistryCarbazoleFluorene010402 general chemistry01 natural sciencesMolecular physics0104 chemical scienceschemistry.chemical_compoundDipolePolarizabilityExcited state0103 physical sciencesPhysical and Theoretical ChemistryBasis setExcitationJournal of Physical Chemistry A
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Gas-Phase Synthesis of the Elusive Trisilicontetrahydride Species (Si3H4)

2016

The bimolecular gas-phase reaction of ground-state atomic silicon (Si; 3P) with disilane (Si2H6; 1A1g) was explored under single-collision conditions in a crossed molecular beam machine at a collision energy of 21 kJ mol–1. Combined with electronic structure calculations, the results suggest the formation of Si3H4 isomer(s) along with molecular hydrogen via indirect scattering dynamics through Si3H6 collision complex(es) and intersystem crossing from the triplet to the singlet surface. The nonadiabatic reaction dynamics can synthesize the energetically accessible singlet Si3H4 isomers in overall exoergic reaction(s) (−93 ± 21 kJ mol–1). All reasonable reaction products are either cyclic or …

010304 chemical physicsElectronic structure010402 general chemistryPhotochemistry01 natural sciences0104 chemical sciencesChemical DynamicsCrossed molecular beamchemistry.chemical_compoundIntersystem crossingchemistryReaction dynamics0103 physical sciencesGeneral Materials ScienceSinglet stateDisilanePhysical and Theoretical ChemistryIsomerizationThe Journal of Physical Chemistry Letters
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Steering the excited state dynamics of a photoactive yellow protein chromophore analogue with external electric fields

2014

Abstract The first excited state of the Photoactive Yellow Protein chromophore exhibits a strong charge transfer character and the dipole moments of the excited and ground states differ significantly. Furthermore, the excited state charge distribution changes during the isomerization of this chromophore. These observations suggest that external electric fields can be used to control photo-isomerization, providing a new concept for developing photochromic devices, such as e-paper or optical memory. To test this idea, we performed excited state dynamics simulations and static calculations of a PYP chromophore analogue (pCK − ) in an external electric field. By adjusting direction and strength…

010304 chemical physicsField (physics)ChemistryCharge densitySurface hoppingChromophore010402 general chemistryCondensed Matter PhysicsPhotochemistry01 natural sciencesBiochemistryMolecular physics0104 chemical sciencesPhotochromismDipoleElectric fieldExcited state0103 physical sciencesPhysics::Atomic and Molecular ClustersPhysics::Chemical PhysicsPhysical and Theoretical Chemistryta116ComputingMilieux_MISCELLANEOUS
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Dynamics of the excited-state hydrogen transfer in a (dG)·(dC) homopolymer: intrinsic photostability of DNA

2018

Multiscale molecular dynamics simulations reveal out-of-plane distortions that favour DNA photostability. A novel photostability mechanism involving four proton transfers and triggered by a nearby Na+ ion is also unveiled.

010304 chemical physicsProtonChemistryBase pairGuanineGeneral ChemistryHydrogen atom010402 general chemistry01 natural sciences0104 chemical sciencesNucleobase[CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistrychemistry.chemical_compoundChemistryChemical physicsExcited state0103 physical sciencesMolecule[CHIM]Chemical SciencesGround stateComputingMilieux_MISCELLANEOUS
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