Search results for "Static load"

showing 3 items of 13 documents

Residential greenness-related DNA methylation changes

2021

Abstract Background Residential greenness has been associated with health benefits, but its biological mechanism is largely unknown. Investigation of greenness-related DNA methylation profiles can contribute to mechanistic understanding of the health benefits of residential greenness. Objective To identify DNA methylation profiles associated with greenness in the immediate surroundings of the residence. Methods We analyzed genome-wide DNA methylation in 1938 blood samples (982 participants) from the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). We estimated residential greenness based on normalized difference vegetation index at 30 × 30 m cell (green3…

Pathway analysisAllergyPhysical activityStress copingHealth benefitsBiologySettore MED/01 - Statistica MedicaCohort StudiesEpigenomeAir PollutionEnvironmental healthEnrichment testHumansGE1-350EWASGeneral Environmental ScienceDNAMethylationGreenness DNA methylation EWAS Enrichment test Pathway analysis Allergy Physical activity Allostatic loadDNA MethylationAllostatic loadEnvironmental sciencesDifferentially methylated regionsGreennessDNA methylationSettore SECS-S/01 - StatisticaCohort study
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A Combined Behavioral and Neuroimaging Battery to Test Positive Appraisal Style Theory of Resilience in Longitudinal Studies

2018

AbstractResilience is the maintenance or rapid recovery of mental health during and after stressor exposure. It is becoming increasingly clear that resilience results from a complex and dynamic process of adaptation to stressors involving the biological, psychological and social levels. Positive appraisal style theory of resilience (PASTOR) claims that the common final pathway to maintained mental health lies in the non-negative (non-catastrophizing, non-pessimistic) appraisal of potential stressors, permitting the organism to fine-tune stress responses to optimal levels, thus avoiding unnecessary stress, inefficient deployment of resources and concomitant deleterious allostatic load effect…

medicine.diagnostic_testmedia_common.quotation_subject05 social sciencesStressorContext (language use)CognitionExtinction (psychology)Mental health050105 experimental psychologyAllostatic load03 medical and health sciences0302 clinical medicinemedicine0501 psychology and cognitive sciencesPsychological resiliencePsychologyFunctional magnetic resonance imaging030217 neurology & neurosurgeryCognitive psychologymedia_common
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The clinical implications of cognitive impairment and allostatic load in bipolar disorder.

2011

AbstractBackgroundAllostatic load (AL) relates to the neural and bodily “wear and tear” that emerge in the context of chronic stress. This paper aims to provide clinicians with a comprehensive overview of the role of AL in patophysiology of bipolar disorder (BD) and its practical implications.MethodsPubMed searches were conducted on English-language articles published from 1970 to June 2011 using the search terms allostatic load, oxidative stress, staging, and bipolar disorder cross-referenced with cognitive impairment, comorbidity, mediators, prevention.ResultsProgressive neural and physical dysfunction consequent to mood episodes in BD can be construed as a cumulative state of AL. The con…

medicine.medical_specialtyBipolar DisorderNeuropsychologyAllostasismedicine.diseaseComorbidityAllostatic loadPsychiatry and Mental healthMoodAllostasismedicineHumansBipolar disorderCognitive declinemedicine.symptomPsychiatryPsychologyCognition DisordersManiaClinical psychologyEuropean psychiatry : the journal of the Association of European Psychiatrists
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