Search results for "Static"

“Bevacizumab (Bev) with irinotecan (IRI), folinic acid (FA), and 5-fluorouracil (FU) i.v. every 2 weeks (BIFF regimen) as first-line treatment for me…

2009

“Bevacizumab (BEV),irinotecan (IRI), folinic acid (FA) and fluorouracil (FU) every 2 weeks (BIFF regimen) as first-line treatment for metastatic colo…

2009

Weekly docetaxel (wDOC) for the treatment of metastatic breast cancer (MBC): A literature based meta-analysis

2010

“Evaluating the prognostic role of serum extracellular domain (ECD) of HER-2/neu (s-HER2) in patients (PTS) with metastatic (M) breast cancer (BC): r…

2009

Dynamic autostatic implant for inguinal hernia repair. Early results in an explorative cohort of patients

2010

Acknowledging the need to further improve outcomes and reduce complications in inguinal hernia repair, our group has been developing new surgical implants for this condition. Our primary considerations are to reduce complications associated with invasive fixation, and improve the quality of the tissue ingrowth within the implant. We have developed a new type of 3D dynamic, self retaining implant to achieve these effects. This newly designed implant was previously experimentally tested in porcine model, showing excellent outcomes. Above all, the results concerning the quality of tissue ingrowth and the nearby absence of shrinkage in the long term were excellent. In this report we describe th…

Studio dell'infiltrato linfocitario peritumorale e dei linfociti circolanti in pazienti affetti da melanoma cutaneo

2014

I linfociti T γδ sono un gruppo di effettori “natural killer” del sistema immunitario innato che hanno rappresentato un interessante oggetto di studio nel corso degli ultimi anni. Il Dipartimento di Discipline Chirurgiche, Oncologiche ed Odontostomatologiche del Policlinico Universitario di Palermo, da anni attivo nei confronti della ricerca scientifica, ha recentemente condotto uno studio mirato alla conoscenza del potenziale effetto immunoterapeutico di questa popolazione linfocitaria verso i melanomi in stadio avanzato. Sulla base della classificazione della American Joint Committee on Cancer (AJCC) i pazienti affetti da melanoma maligno in stadio IV con neoplasia metastatica hanno una p…

[Letter to the Editor] Bipolar radiofrequency ablation for metastatic spinal tumors: an evolving paradigm in palliative care

2015

I read with great interest the article by Wallace and col- laborators focusing on the combination of radiofrequency ablation (RFA) and vertebral augmentation for palliation of painful spinal metastases [1]. In a retrospective approach the authors reviewed a group of patients who underwent RFA for vertebral metastases in a period spanning almost 2 years. In a cohort of 110 patients, 72 RFA procedures were performed. Interestingly, 81 % of the metastatic lesions involved the posterior vertebral body and 45 % the pedicles. In almost all the cases, vertebral augmentation was performed following the ablation procedure.

Alteration of the structural properties of inulin gels

2019

Abstract In this work, inulin particle gels, prepared with a type of long chain inulin, were examined in terms of their structural properties and mechanical response, depending on the applied shear rates and temperature during gel preparation. The results are interpreted on the basis of a particle gel model, which takes into account the varying gel structure, depending on the sample preparation parameters. X-ray measurements of the inulin powder, used for the experiments, revealed a mostly amorphous powder. The temperature profiles for the sample preparation, chosen from 25 °C to 60 °C with constant stirring at 600 rpm, yielded viscoelastic particle gels with decreasing hardness. By applica…

Sequence stratigraphy of a mesozoic carbonate platform-to-basin system in Western sicily

2009

Abstract Sequence stratigraphic studies of the Triassic through Paleogene carbonate successions of platform, slope and basin in western Sicily (Palermo and Termini Imerese Mountains) have identified a sedimentary cyclicity mostly caused by relative oscillations of sea level. The stratigraphic successions of the Imerese and Panormide palaeogeographic domains of the southern Tethyan continental margin were studied with physical-stratigraphy and facies analysis to reconstruct the sedimentary evolution of this platform-to-basin system. The Imerese Basin is characterized by a carbonate and siliceous-calcareous succession, 1200–1400m thick, Late Triassic to Eocene in age. The strata display a typ…

Implementation of preventive and predictive BRCA testing in patients with breast, ovarian, pancreatic, and prostate cancer: a position paper of Itali…

2022

Constitutional BRCA1/BRCA2 pathogenic or likely pathogenic variants (PVs) are associated with an increased risk for developing breast and ovarian cancers. Current evidence indicates that BRCA1/2 PVs are also associated with pancreatic cancer, and that BRCA2 PVs are associated with prostate cancer risk. The identification of carriers of constitutional PVs in the BRCA1/2 genes allows the implementation of individual and family prevention pathways, through validated screening programs and risk-reducing strategies. According to the relevant and increasing therapeutic predictive implications, the inclusion of BRCA testing in the routine management of patients with breast, ovarian, pancreatic and…